Abstract: A hierarchical system architecture for controlling an automated vehicle. The hierarchical system architecture includes: a performance layer; a safety layer; a hardware layer, wherein the safety layer is arranged between the performance layer and the hardware layer; the performance layer is configured to generate a first control signal and to transmit it to the safety layer; the safety layer is configured to detect whether a safety-critical driving situation is present for the vehicle, and a first system reaction is to be carried out to bring the vehicle into a safe state by transmitting a corresponding second control signal to the hardware layer instead of the first control signal, and the safety layer includes at least one detector module which detects whether a special case is present in the safety-critical driving situation of the vehicle which requires an associated second system reaction instead of the first system reaction.

Abstract: RNAs, such as miRNA and siRNA, and their use in treating complement-mediated disorders, are described.

Abstract: A computer-implemented method for gradient delay time correction of MR data using an MR device, wherein the magnetic resonance data is recorded using a three-dimensional recording technique with linear recording trajectories which are oriented in different readout directions of a readout plane that is perpendicular to a partition direction. The method includes: in a calibration measurement using the magnetic resonance device, recording calibration data which describes readout-direction-dependent shifts, caused by delay effects, of measurement points in the k-space; determining correction data by evaluating the calibration data; correcting the MR data based on the correction data in order to compensate for the delay effects, wherein the calibration data, which covers a coverage region in partition direction is recorded in a resolved manner, and the correction data is determined and applied in a manner that is dependent on partition direction.

Abstract: Systems, methods and computer-readable memory devices are provided for greater efficiency in the configuration of a database cluster for performing a query workload. A database cluster configuration system is provided that includes a database cluster comprising one or more compute resources configured to perform database queries. A query workload comprising a plurality of queries is received. An initial workload-level configuration is applied. For each query of the query workload, a query-level configuration is generated using a query configuration model corresponding to each query in a contextual Bayesian optimization with centroid learning while also leveraging the query plan for each executing query for query characterization and including application of virtual operators. Query events are collected and used to update the corresponding query configuration model. The workload-level configuration is updated based on the query events and cached for use during a subsequent execution of the workload.

Abstract: A method including receiving, by a repeater, access link information from an access point over a backhaul link, wherein the access link information includes received power of one or more reference signals, or an indication of a spatial filter for an access link; and obtaining, by the repeater, based at least partly on the access link information, at least one spatial filter pair for the backhaul link and the access link.

Abstract: The disclosure relates to gradient delay time correction of magnetic resonance data. For recording the magnetic resonance data, use is made of a three-dimensional recording technique with linear recording trajectories oriented in different readout directions of a readout plane that is perpendicular to a partition direction. Calibration data is recorded which covers a plurality of partitions in partition direction and which describes readout-direction-dependent shifts, caused by delay effects, of measurement points, e.g. sampled k-space sections in the k-space. Correction data is determined by evaluating the calibration data, and the magnetic resonance data is corrected on the basis of the correction data in order to compensate for the delay effects. The calibration data, which covers a coverage region in partition direction, is recorded in a resolved manner in partition direction, and at least one acceleration technique is applied in the partition direction during the recording of the calibration data.

Abstract: A method, computer program product, and computing system for processing training data and prediction data as a plurality of tokens using a classification-based machine learning model. A plurality of weighting features associated with the training data and the prediction data are defined by processing the output of the machine learning model with an attention layer. The plurality of weighting features are reshaped to generate weights for a trained neural network by processing the plurality of weighting features with an attention layer.

Abstract: The invention relates to a holding system (1) for holding substrates (12) for use in a surface processing system having a covering area (20), comprising a plurality of fixing elements (2), a body (24) arranged within the covering area (20) for receiving the fixing elements (2), and a positioning element (26) for adjusting the covering and a machining area (20, 22), wherein a plurality of substrates (12) can be fixed by the fixing elements (2) and processed within the machining area (22).

Abstract: A liner system for applying to a limb or a limb stump, with an inner liner comprising an inner side facing the limb or limb stump and an outer side facing away from the limb or limb stump, and an outer liner that comprises an inner side facing the inner liner and an outer side facing away from the inner liner. The outer liner is designed to be applied over the inner liner, with a sealing element which is designed to be separate from the inner liner and the outer liner, for arranging between the outer side of the inner liner and the inner side of the outer liner.

Abstract: An optical imaging device for a microscope includes an objective and an optical system configured to interact with the objective for optically imaging an object selectively in a first operating mode and a second operating mode. The optical system includes a first optical subsystem associated with the first operating mode, and a second optical subsystem associated with the second operating mode. The first optical subsystem is configured to form a first image of the object with a first magnification. The second optical subsystem is configured to form a second image of the object with a second magnification that is less than the first magnification. The second optical subsystem includes an optical module insertable into the optical path for selecting the second operating mode. The optical module includes a lens element with a positive refractive power.

Abstract: The invention relates to a method for calibrating, in particular, sintered pressed parts, wherein a calibration procedure of each individual pressed part is controlled depending on at least one specific pressed part parameter of the respective pressed part measured before calibration and/or depending on at least one production parameter of a preceding pressing and/or sintering step of the respective pressed part.

Abstract: Various example embodiments relate to devices, methods, apparatuses and computer readable mediums for virtual cable calibration in over the air conformance testing. In an example embodiment, a terminal device may receive training signals from at least four probes, estimate a channel based on the received training signals, and transmit a representation of the estimated channel to a test equipment coupled to the at least four probes. The terminal device and the at least four probes are positioned in a testing chamber. The estimated channel includes an over the air, OTA, channel portion between the at least four probes and the terminal device. The representation of the estimated channel is transmitted to the test equipment for compensation of the OTA channel portion.

Abstract: A vaporizer cartridge for an inhaler has a hollow body with a continuous flow channel and liquid storage tank. The tank has an access opening to the channel and a vaporizer unit extending over the entire access opening. The vaporizer unit has a wick member and a heating member. The vaporizer unit is liquid-permeable such that liquid is conveyed at least initially in a capillary manner from the storage tank through the vaporizer unit in the direction of the flow channel. The wick member is formed from a plurality of granular grains which, as a result of their fill and/or formation, form microchannels which establish a fluid connection between the storage tank and the flow channel, continuously from an entry side to an exit side of the wick member. An additional securing means is provided which is holds the granular wick member in position. A corresponding inhaler is also provided.

Abstract: The invention relates to a method for producing an orthopedic device, particularly a prosthesis liner, characterized in that the orthopedic device is produced at least partially by means of an additive manufacturing process from at least one production material that is introduced into a support material in a flowable state and then hardens.

Abstract: A wafer includes a substrate and at least one intermediate layer formed on a surface of the substrate. The at least one intermediate layer covers the surface of the substrate at least partially. An outer surface of the at least one intermediate layer is directed away from the surface of the substrate. The wafer further includes nanostructures grown on the outer surface of the at least one intermediate layer. The at least one intermediate layer is formed in such a way that positions of growth of the nanostructures are predetermined on the outer surface of the at least one intermediate layer. At least one nanostructure material of the nanostructures is assembled at the positions of growth of the nanostructures.

Abstract: The invention relates to a conjugate comprising (a) an amatoxin comprising (i) an amino acid 4 with a 6?-deoxy position; and (ii) an amino acid 8 with an S-deoxy position; (b) a target-binding moiety; and (c) optionally a linker linking said amatoxin and said target-binding moiety. The invention furthermore relates to a pharmaceutical composition comprising such conjugate.

Abstract: A method for electrically conductively contacting an optoelectronic component having at least one protective layer, including: providing the optoelectronic component having the at least one protective layer with at least one busbar arranged below the at least one protective layer, forming at least one opening by at least one laser beam in the at least one protective layer, wherein at least one busbar arranged below the at least one protective layer is partly exposed, such that the at least one busbar is not damaged, introducing a low-melting solder into the at least one opening of the at least one protective layer, aligning and fixing an electrically conductive element that is flexible on a side of the at least one opening opposite the at least one busbar, and forming an electrically conductive connection element in the at least one opening.

Abstract: A method for increasing safety at a crossing system including crosswalk.

Abstract: The invention relates to various aspects of a ?-LED or a ?-LED array for augmented reality or lighting applications, in particular in the automotive field. The ?-LED is characterized by particularly small dimensions in the range of a few ?m.

Abstract: A polymer composition comprising: (i) at least 40 wt % LDPE; (ii) a polypropylene homopolymer; and (iii) a random heterophasic polypropylene copolymer.