Abstract: A process for purifying a pyrolysis product. for example a pyrolysis oil and/or a pyrolysis gas. originating from pyrolysis of plastic waste is provided. wherein the process comprises contacting a vaporized pyrolysis oil with one or more adsorption materials and condensing the vaporized pyrolysis oil after it has been contacted with the one or more adsorption materials.

Abstract: The present disclosure provides gene therapy that targets complement pathways for treating dry age-related macular degeneration.

Abstract: Aspects of the disclosure relate to compositions and methods for epigenetic regulation of endogenous gene expression from viral vectors. In some embodiments, the disclosure provides expression constructs comprising a viral vector encoding a transgene, the activation of which is regulated by a rapamycin/rapalog-based system, and the transgene is capable of epigenetically regulate an endogenous gene.

Abstract: A polymer composition comprising (i) 4.95 to 95.0 wt. % low density polyethylene (LDPE) (component (i), herein after); (ii) 4.95 to 95.0 wt. % of a polypropylene (component (ii), herein after); and (iii) 0.00 to 30.0 wt. % of a styrene block copolymer (component (iii), herein after); (iv) 0.05 to 10.0 wt. % of an aliphatic, preferably alkyl, functionalized inorganic nanoparticle filler (component (iv), herein after); whereby the weight percentages (wt. %) are expressed relative to the total weight of the polymer composition.

Abstract: The invention relates to a method for producing an orthopedic device, particularly a prosthesis liner, characterized in that the orthopedic device is produced at least partially by means of an additive manufacturing process from at least one production material that is introduced into a support material in a flowable state and then hardens.

Abstract: A semiconductor module arrangement includes a substrate including a dielectric insulation layer and a first metallization layer arranged on a surface of the dielectric insulation layer, wherein the first metallization layer comprises a first section, a second section, and a third section, and a first semiconductor body and an identical second semiconductor body arranged on the first metallization layer, wherein each of the first semiconductor body and the second semiconductor body has a first contact pad, a second contact pad, and a third contact pad arranged on a top side of the respective semiconductor body that faces away from the substrate, wherein the third contact pad of the first semiconductor body is electrically coupled to the third section of the first metallization layer by means of a first electrical connection element, the third contact pad of the second semiconductor body is electrically coupled to the third section of the first metallization layer by means of a second electrical connection elem

Abstract: An electronic device including a master device, the master device including an interface component to a slave device. The interface component includes a sampling circuit having a clock input, a transmit clock generator configured to generate a transmit clock, a first off-chip driver configured to receive the transmit clock and provide the transmit clock to the slave device, a second off-chip driver configured to receive the transmit clock and configured to supply the transmit clock to the clock input of the sampling circuit of the interface component and a data input configured to receive data from the slave device. The sampling circuit is configured to sample the received data in accordance with the transmit clock supplied by the second off-chip driver.

Abstract: An inclination compensating device for a carriage of a conveyor device for the horizontal transport of conveyed material, wherein a drive element is driven via the pivot drive, which drive element is fastened to an end of a pivot lever extending away from the inclination compensating element, which end is opposite the inclination compensating element, and which drive element has a drive axis arranged parallel or perpendicular to the pivot axis, wherein the drive element rolls on at least one guide, in particular extending equidistantly to the pivot axis, in particular in a force-locking or form-locking manner, which guide is mounted or formed on the holding frame.

Abstract: A computer-implemented method and a corresponding system for planning the behavior of a vehicle using a predefined set of rules with prioritized rules for assessing possible behaviors of the vehicle in a given situation. For this purpose, situation-specific information is aggregated, and an environmental model of the given situation is generated based on the aggregated situation-specific information. The set of rules includes a decision-making process structure, which represents the prioritization of the individual rules of the set of rules. On the basis of the environmental mode, boundary conditions for the possible behaviors of the vehicle are determined. The latter are then prioritized by applying the decision-making process structure to the respective boundary conditions.

Abstract: A method, computer program product, and system for detecting and mitigating ransomware using snapshot-based backups applied to a block-oriented storage device, by performing the following operations: (i) performing, in predetermined time-intervals, snapshot backups of data in a block-oriented storage device; (ii) determining at least one interval malware index value between a last snapshot backup and a next planned snapshot backup, wherein the interval malware index value is indicative of a changed block rate in stored data of storage blocks of the block-oriented storage device; and (iii) in response to determining that the interval malware index value is larger than a predefined interval malware index threshold value, triggering an emergency snapshot.

Abstract: The invention relates to isolated nucleic acids and rAAV-based compositions, methods and kits useful for treating genetic diseases (e.g., alpha-1 antitrypsin deficiency).

Abstract: A computer-implemented method for the behavior planning of an at least partially automated EGO vehicle. The method uses a database of pre-defined partial situations and an evaluation model for each partial situation, as well as a pre-defined rule set for evaluating possible behaviors of the EGO vehicle in a given situation. The EGO vehicle performs: aggregating situation-specific information; generating an environment model of the given situation based on the situation-specific information; analyzing the environment model to identify at least one partial situation in the database; generating at least one instance for each identified partial situation; analyzing all generated instances by using the evaluation model of the respectively underlying partial situation to determine boundary conditions for the possible behaviors of the EGO vehicle in the given situation; prioritizing the possible behaviors of the EGO vehicle based on the boundary conditions determined in this way in conjunction with the rule set.

Abstract: A power semiconductor module arrangement includes a substrate including a dielectric insulation layer and a first metallization layer arranged on a first side of the dielectric insulation layer, wherein the first metallization layer includes a plurality of different sections that are separate and distinct from each other, and a plurality of semiconductor bodies arranged on the first metallization layer, and including a first sub-group of semiconductor bodies and a second sub-group of semiconductor bodies, wherein the semiconductor bodies of the first sub-group differ from the semiconductor bodies of the second sub-group, wherein each of the plurality of semiconductor bodies includes a control electrode and a controllable load path between a first load electrode and a second load electrode, the first sub-group is symmetrical to the second sub-group.

Abstract: A charging device for electric vehicles, comprising at least one docking station, at least one charging unit attachable to the docking station. The docking station has plurality of recesses. The charging unit has a plurality of bars insertable into the docking station recesses, each of which comprises at least one first locking element, at least one locking module movable between a locking position and an open position which has a plurality of second locking elements corresponding to the first locking elements. In the open position of the locking module, the bars are insertable into the recesses in such a way that the bars are movable into a snapping position, In the snapping position, the locking module is movable from the open position into the closed position such that the bars are positively fixable to the docking station by an interaction of the second locking elements with the first locking elements.

Abstract: Aspects of the disclosure relate to recombinant gene editing complexes comprising a recombinant gene editing protein and guide RNA (gRNA) that specifically hybridizes to a region of a C90RF72 gene (e.g., a region flanking a G4C2 repeat or within a exonic region of the gene).

Abstract: A furniture drive includes an electric drive motor and a brake device. The drive motor has an output shaft which projects beyond a motor housing and the brake device has at least one brake element and one force accumulator. The force accumulator permanently loads a friction surface of the at least one brake element with a brake force. The force accumulator and the brake element are configured in one piece. Coefficients of static and sliding friction between the friction surface of the brake element and the output shaft differ by a factor of at least 1.3. An EMF brake is provided for the drive motor.

Abstract: A tracking server may receive, from a requester, a content request for accessing a content element on a content server. The content request includes a request URL with at least a content identifier specifying the requested content element on the content server, and a request referral identifier. If the content identifier does not refer to a content element provided on the content server, an error response is sent. If the content identifier refers to a content element provided on the content server, a new and unique referral identifier associated with the content request is generated. Further, a new and unique referral URL for the content request is generated as a response URL comprising the received content identifier and the newly generated unique referral identifier. The requested content element is then served to the requester under the response URL.

Abstract: The invention relates to a device for removing powder and/or particles from a powder bed. The device comprises a rotatably mounted roller having a porous outer wall and comprises a plurality of chambers formed inside the roller. The device also comprises a connection for negative-pressure supply that is designed to supply at least one of the chambers with negative pressure at a given point in time. The at least one of the chambers has an opening which is suitable for supplying the chamber with negative pressure.

Abstract: Techniques, described herein, include solutions for evaluating a pre-failure condition of a data link. The techniques described allow for detection of the pre-failure condition before actual failure of the data link. A device may receive a first set of training data and compare the first set of training data to a pre-determined set of training data to obtain a first set of values at a first time. The process may be repeated at a second time with a second set of training data and a second set of values respectively. First and second quality metrics may be obtained using the first and second set of values respectively. Based on the first and second quality metrics and a time interval between the first and second times, the pre-failure condition may be determined.

Abstract: Systems, methods, and devices are described for enabling a user to import a library into a computer program under development. The library includes a data storage interface, one or more semantic objects, and one or more data manipulation or data analysis operations. A user is able to reference code of the library within the computer program under development to generate a dataset from data obtained via the data storage interface and associate the one or more semantic objects with the dataset to generate a semantically-annotated dataset. Systems, methods, and devices enable, based on the importing: the user to invoke a semantic-guided operation of the library that utilizes the semantically-annotated dataset to infer an aspect of a data manipulation or data analysis operation to be performed on the semantically-annotated dataset; or the suggestion of a data manipulation or data analysis operation to the user based on the semantically-annotated dataset.