Abstract: Systems, methods, and devices are described for enabling a user to import a library into a computer program under development. The library includes a data storage interface, one or more semantic objects, and one or more data manipulation or data analysis operations. A user is able to reference code of the library within the computer program under development to generate a dataset from data obtained via the data storage interface and associate the one or more semantic objects with the dataset to generate a semantically-annotated dataset. Systems, methods, and devices enable, based on the importing: the user to invoke a semantic-guided operation of the library that utilizes the semantically-annotated dataset to infer an aspect of a data manipulation or data analysis operation to be performed on the semantically-annotated dataset; or the suggestion of a data manipulation or data analysis operation to the user based on the semantically-annotated dataset.

Abstract: In some aspects, the disclosure relates to compositions and methods useful for inhibiting SOD1 expression in cells (e.g., cells of a subject). In some embodiments, the disclosure describes isolated nucleic acids engineered to express an inhibitory nucleic acid targeting endogenous SOD1 and an mRNA encoding a hardened SOD1 protein. In some embodiments, compositions and methods described by the disclosure are useful for treating Amyotrophic Lateral Sclerosis (ALS) in a subject.

Abstract: Performance degradation of an application that is caused by another computing process that shares infrastructure with the application is detected. The application and the other computing device may execute via different virtual machines hosted on the same computing device. To detect the performance degradation that is attributable to the other computing process, certain storage segments of a data storage (e.g., a cache) shared by the virtual machines is written with data. A pattern of read operations are then performed on the segments to determine whether an increase in read access time has occurred. Such a performance degradation is attributable to another computing process. After detecting the degradation, a metric that quantifies the detected degradation attributable to the other computing process is provided to an ML model, which determines the actual performance of the application absent the degradation attributable to the other computing process.

Abstract: The present invention relates to a process for purifying a crude nitrogen-containing, sulfur-containing, halogen-containing pyrolysis oil originating from the pyrolysis of plastic waste, comprising (i) subjecting the crude pyrolysis oil to a treatment with a trapping agent selected from (a) an elemental metal of group 1, 2, 6, 7, 8, 9, 10, 11, 12, 13 of the IUPAC periodic table, a mixture or an alloy thereof; (b) an oxide of metals of group 1, 2, 6, 7, 8, 9, 10, 11, 12, 13 of the IUPAC periodic table or a mixture thereof; (c) an alkoxide of metals of group 1, 2 of the IUPAC periodic table or a mixture thereof; (d) a solid sorption agent as defined in the claims; or a combination of at least two trapping agents (a), (b), (c) or (d); (ii) separating the product obtained into a purified pyrolysis oil fraction having a reduced nitrogen, sulfur and halogen content in relation to the crude pyrolysis oil and a fraction comprising the trapping agent which has bound at least a part of the sulfur, nitrogen, halogen pre

Abstract: The present invention relates to an ethylene polymer composition comprising: (A) an ethylene polymer comprising epoxy-groups, and (B) a cross-linking agent comprising: (B1) an organo-metallic Lewis acid, and at least one of: (B2) a compound comprising at least one amino group; and (B3) a compound comprising at least one hydroxyl group.

Abstract: The present invention relates to a cross-linkable polyolefin composition comprising a first olefin polymer (A) comprising a first comonomer comprising epoxy groups, and a second olefin polymer (B) comprising a second comonomer comprising carboxylic acid groups and/or precursor thereof.

Abstract: An inclination compensating device for a carriage of a conveyor device for the horizontal transport of conveyed material, wherein a drive element is driven via the pivot drive, which drive element is fastened to an end of a pivot lever extending away from the inclination compensating element, which end is opposite the inclination compensating element, and which drive element has a drive axis arranged parallel or perpendicular to the pivot axis, wherein the drive element rolls on at least one guide, in particular extending equidistantly to the pivot axis, in particular in a force-locking or form-locking manner, which guide is mounted or formed on the holding frame.

Abstract: A polymer composition comprising: (i) at least 40 wt % LDPE; (ii) a polypropylene homopolymer; and (iii) a random heterophasic polypropylene copolymer.

Abstract: A communication device with an activated ring controller provided in both first and second subnetworks for data transmission in a redundantly operable communications network, which includes at least one first and one second subnetwork, which each include communication devices interconnected within a ring topology, wherein the subnetworks are interconnected via coupling line sections to which coupling communication devices are connected, where the coupling line section to which a selected coupling communication device is connected is operated as an inactive reserve coupling line section until a disruption occurs, whilst another coupling line section is operated as an active main coupling line section, where coupling communication devices connected to the main coupling line section transmit status datagrams to the selected coupling communication device which additionally include configuration information about whether the particular coupling communication device connected to the main coupling line section is an

Abstract: The invention provides a polyolefin composition comprising (i) a polyolefin (A) comprising epoxy groups; and (ii) a polyolefin (B) comprising carboxylic acid groups and/or precursors thereof, with the proviso that at least one of (A) and (B) is polyethylene. Preferably one of (A) and (B) is a low density polyethylene (LDPE) and the other is a polypropylene.

Abstract: The invention provides a polymer composition comprising a) a low density polyethylene (LDPE); and b) a conjugated aromatic polymer. The invention also relates to cables comprising said polymer composition and the use of the polymer composition in the manufacture of an insulation layer of cable.

Abstract: Aspects of the disclosure relate to compositions and methods for regulation of transgene (e.g., miRNAs, shRNAs or coding sequences) expression from viral vectors. In some embodiments, the disclosure provides expression constructs comprising a viral vector encoding one or more transgenes, the expression of which is regulated by a rapamycin/rapalog-based system.

Abstract: The present disclosure provides nucleic acid molecules comprising a first inverted terminal repeat (ITR), a second ITR, and a genetic cassette encoding a target sequence. In some embodiments, the first ITR and/or the second ITR is an ITR of human bocavirus. Also disclosed are methods of using the nucleic acid molecules in gene therapy applications.

Abstract: A polymer composition comprising (i) at least 70 wt% of low-density polyethylene (LDPE) homopolymer or copolymer having a density of 905 to 935 kg/m3 (ISO 1183-2) and an MFR2 of 0.1 to 10 g/10 min (ISO1133 at 190° C., 2.16 kg); (ii) 0.5 to 20 wt % of a high density polyethylene (HDPE) having a density of 940 kg/m3 or more and an MFR2 of 0.1 to 50 g/10 min; and (iii) 0.05 to 10 wt% of an aliphatic, preferably alkyl, functional inorganic nanoparticle filler.

Abstract: In an embodiment a measuring unit includes a light emitting LED component including a housing occupying a housing surface G and an LED chip located within the housing, the LED chip including a light emitting light surface L and being configured to emit light; a photodetector configured to detect reflected light reflected from a measured object originating from the LED component and output a measurement signal dependent on a detection of the reflected light; and an integrated circuit configured to evaluate the measurement signal, wherein the LED component, the photodetector, and the integrated circuit are combined into an integrated unit; and a conversion layer disposed in the housing and located above the LED chip, the conversion layer configured to convert the light into multiband light, wherein a ratio L/G of is greater than or equal to 0.8, and wherein the measuring unit is configured to optically measure at least one property of the measured object.

Abstract: The invention relates to a seal system (100, 200, 300) for an installation (400) for producing a three-dimensional workpiece by means of an additive layer manufacturing method, the seal system (100, 200, 300) comprising: a first seal (102), which is configured to seal an intermediate space (116) at a first periphery (108) between a process chamber inner wall (110) and a powder-material-supporting plate assembly (112) in a process chamber (410) of the installation (400); and a second seal (104), which is configured to seal the intermediate space (116) at a second periphery (114) between the process chamber inner wall (110) and the powder-material-supporting plate assembly (112) in the process chamber (410) of the installation (400), the first seal (102) being spaced apart from the second seal (104) such that, when the intermediate space (116) is sealed between the process chamber inner wall (110) and the plate assembly (112) by means of the first seal (102) and the second seal (104), a channel (106) is formed

Abstract: The invention relates to a highly reactive, high-purity, free-flowing and dust-free lithium sulfide powder having an average particle size between 250 and 1,500 ?m and BET surface areas between 1 and 100 m2/g. The invention, furthermore, relates to a process for its preparation, wherein in a first step, lithium hydroxide monohydrate is heated in a temperature-controlled unit to a reaction temperature between 150° C. and 450° C. in the absence of air, and an inert gas is passed over or through it, until the residual water of crystallization content of the formed lithium hydroxide is less than 5 wt. % and in a second step, the anhydrous lithium hydroxide formed in the first step is mixed, overflowed or traversed by a gaseous sulfur source from the group consisting of hydrogen sulfide, elemental sulfur, carbon disulfide, mercaptans or sulfur nitrides.

Abstract: Weighing systems and methods for dynamic loads are provided. A plurality of sensors are configured to provide force information based on a weight of a bin and a weight of a material in the bin. An IMU is coupled to the bin and configured to provide gyroscope information and accelerometer information based on orientation and movement of the bin respectively. A controller is communicatively coupled to the plurality of sensors and to the IMU. The controller is configured to receive the force information from the plurality of sensors and the gyroscope information and the accelerometer information from the IMU. The controller is configured to compensate the force information based on slope of the bin to provide slope-compensated force information, filter the slope-compensated force information using a Kalman filter to provide filtered force information, and estimate the weight of the material in the bin based on the filtered force information.

Abstract: RNAs, such as miRNA and siRNA, and their use in treating complement-mediated disorders, are described.

Abstract: The invention relates to various aspects of a ?-LED or a ?-LED array for augmented reality or lighting applications, in particular in the automotive field. The ?-LED is characterized by particularly small dimensions in the range of a few ?m.