Abstract: A drug delivery device (1) comprises a housing and an expelling assembly adapted to expel a dose of drug from a cartridge (380). The expelling assembly comprises a drive spring (135) which in an energized state is adapted to drive the expelling assembly, a rotating component (550,650) adapted to rotate relative to an axis of rotation during expelling of a dose of drug, and user actuated release means (191, 190) for releasing the drive spring to thereby expel a dose of drug. The device is provided with a brake element (575, 675) being moveable in a plane generally perpendicular to the axis of rotation, the brake element being adapted to engage the rotating component such that during rotation thereof the brake element is moved back and forth, whereby the brake element provides a braking action on the rotating component.

Abstract: The present invention concerns a medical injection device for apportioning set doses of a preservative containing liquid drug. The injection device comprises a housing supporting a cartridge containing the preservative containing liquid drug and a needle cannula for transferring the liquid drug from the cartridge and through the skin of a user. Further, a needle shield which is axially movable in relation to the housing is also present. The axially movable shield carries a cleaning reservoir for cleaning at least the tip of the needle cannula between subsequent injections and the cleaning reservoir is preferably filled with preservative containing liquid drug directly from the cartridge upon initiation of the injection device. In order to eliminate any overpressure being built up inside the cleaning reservoir during the filling process, the cleaning reservoir is provided with an outlet configured to be permanently sealed by a user activated operation.

Abstract: A single-use auto-injector includes a housing and a dosing unit in at least part of the housing. The dosing unit includes a needle, a drug container with drug, a piston movable in the container, a first mechanical power supply for moving the piston to deliver the drug, an activation mechanism, and a mechanical escapement mechanism for controlling the movement of the piston. The auto-injector has a first state in which the needle is protected from needle damage or contamination, a second state in which the needle is ready to penetrate a human body, a third state in which the needle has penetrated the human body and is ready to dose, and a fourth state in which the needle is shielded to avoid unintended needle sticks. A second mechanical power supply is configured to shift state of the auto-injector from the third state to the fourth state.

Abstract: A drug delivery device comprises a housing (201) and an expelling assembly with a piston rod (220), a drive tube (260) with an outer surface and a scale drum (270) arranged between the drive tube and the housing, the scale drum being coupled to the housing and the drive tube outer surface. The device further comprises a drive spring (255) arranged between the housing and the drive tube, and setting means (280) allowing a user to simultaneously set a dose amount to be expelled and strain the drive spring correspondingly by rotation of the drive tube. The scale drum is coupled to the drive tube via a spline connection, wherein the drive spring is arranged proximally of the spline connection when the spline connection is in its proximal-most position.

Abstract: A drug delivery device comprising a rotatable scale drum, a trigger member, an actuation member, a trigger spring acting on the trigger member and being energized by movement of the actuation member, as well as an end-of-dose switch adapted to be actuated by movement of the trigger member. The trigger member is adapted to be arranged in an axially supported position against the action of the energized trigger spring, and released from the axially supported position when the scale drum is rotated from a set position to an end-of-dose position, whereby the trigger member is moved axially by the trigger spring, the end-of-dose switch thereby being actuated.

Abstract: The present invention relates to medicament injection devices (100). A cartridge (600) with a septum and a needle unit (500) having front and rear needles (510, 520) are configured for relative movement from a state where the septum is sealed to a state where the septum is pierced by the rear needle (520). The injection device (100) may include a needle shield (350) and be configured for piercing the septum by the rear needle (520) when the front needle (510) is operated relative to the needle shield (350). The injection device (100) may also include a damping mechanism configured for limiting the speed of movement of the cartridge relative to the needle unit. The injection device (100) may also include an indicator generating a signal when a piston driver has travelled the complete stroke length, wherein the indicator has a deflection element that is deflected prior to or during movement of the cartridge relative to the housing.

Abstract: The present invention relates to a drug delivery device (100) comprising a housing (101), a threaded piston rod (102), a rotatable drive tube (103), a drive nut (104) in threaded engagement with the piston rod (102) and being rotationally locked but axially moveable relative to the drive tube (103), and a support member (105) arranged rotationally free on the piston rod (102), the support member (105) being axially locked relative to the housing (101) and arranged to allow the drive tube (103) to move axially. The device further comprises a compression drive spring (106) arranged between the piston rod (102) and the drive tube (103), the compression drive spring (106) being arranged axially between the drive nut (104) and the support member (105).

Abstract: A drug delivery system is provided including a drug expelling structure adapted to expel a set dose from a drug-filled cartridge, the expelling structure including a rotational member adapted to rotate relative to a housing and corresponding to a set and/or expelled dose, the system including a sensor adapted to detect a set and/or an expelled dose. The sensor includes a first portion mounted to and rotating with the rotational member, and a second portion including a second rotary sensor part mounted non-rotationally relative to the housing. The first portion includes electronic circuitry, and a first rotary sensor part, and the second portion includes a second rotary sensor part mounted non-rotationally relative to the housing. The first and second rotary sensor parts rotate relative to each other during setting and/or expelling of a dose of drug.

Abstract: The present invention relates to injection devices for injecting a dose of a medicament. The injection device (100) incorporates a housing (101), a needle assembly (150) and a cover (200). The needle assembly (150) comprises an injection needle (152,153) accommodated in a needle container (151) having an opening which in a storage state of the injection device (100) is sealed by a film seal (155). The cover may include sections (201,202) arranged movable relative to the housing (101). The injection device (100) is so configured that upon movement of the cover sections (201,202) relative to the housing (101) the film seal (155) is changed from a sealing state to an unsealing state for shifting the injection device (100) into a ready-to-administer state.

Abstract: A portable pen-type drug injection device (300) comprises a main portion (301) and a clip (360). The clip comprises a base portion mounted to a portion of the drug delivery device, and a clip gripping portion with a free end. The device further comprises drug expelling means having dose setting means (340) allowing a user to set a dose of drug to be expelled, and a piston rod adapted to move a piston of a loaded cartridge in a distal direction to thereby expel drug from the cartridge. Electronic circuitry comprises sensor means adapted to detect a set and/or an expelled dose, and a display (374) is provided to display dose-related values, wherein at least a portion of the display is arranged in the flexible clip main portion.

Abstract: The invention provides a drug delivery device adapted to receive a cartridge, the cartridge being adapted to receive a needle assembly. The drug delivery device comprises a front-loaded cartridge holder adapted to receive and hold a cartridge in a mounted state and being actuatable between an open loading state and a closed operational state. The drug delivery device is further provided with blocking means configured to prevent the cartridge holder from being actuated between the closed and the open state when a cartridge with a mounted needle assembly is held in a mounted position.

Abstract: A drug delivery device (1) comprises a housing and an expelling assembly adapted to expel a dose of drug from a cartridge (380). The expelling assembly comprises a drive spring (135) which in an energized state is adapted to drive the expelling assembly, a rotating component (550,650) adapted to rotate relative to an axis of rotation during expelling of a dose of drug, and user actuated release means (191, 190) for releasing the drive spring to thereby expel a dose of drug. The device is provided with a brake element (575, 675) being moveable in a plane generally perpendicular to the axis of rotation, the brake element being adapted to engage the rotating component such that during rotation thereof the brake element is moved back and forth, whereby the brake element provides a braking action on the rotating component.

Abstract: Dial up/dial down spring-driven drug delivery device comprising a rotatable driver assembly allowing a user to set a dose amount to be expelled and strain a drive spring correspondingly. A rotatable ratchet member is coupled to the driver assembly with a rotational play, the play allowing the driver assembly to release the ratchet member and thereby decrease a set dose. A helically moving scale drum is coupled to the driver assembly and comprises a stop surface preventing the driver assembly from being rotated below an initial position, whereby the driver assembly in the initial position is prevented from being rotated in the resetting direction relative to the ratchet member corresponding to the rotational play.

Abstract: A drug delivery system is provided comprising drug expelling means adapted to expel a set dose from a drug-filled cartridge, the expelling means comprising a rotational member adapted to rotate relative to a housing and corresponding to a set and/or expelled dose, the system comprising a sensor adapted to detect a set and/or an expelled dose. The sensor comprises a first portion mounted to and rotating with the rotational member, and a second portion comprising a second rotary sensor part mounted non-rotationally relative to the housing. The first portion comprises electronic circuitry, and a first rotary sensor part, and the second portion comprises a second rotary sensor part mounted non-rotationally relative to the housing. The first and second rotary sensor parts rotate relative to each other during set- ting and/or expelling of a dose of drug.

Abstract: The present invention relates to injection devices for injecting a dose of a medicament. The injection device (100) incorporates a housing (101), a needle assembly (150) and a cover (200). The needle assembly (150) comprises an injection needle (152,153) accommodated in a needle container (151) having an opening which in a storage state of the injection device (100) is sealed by a film seal (155). The cover may include sections (201,202) arranged movable relative to the housing (101). The injection device (100) is so configured that upon movement of the cover sections (201,202) relative to the housing (101) the film seal (155) is changed from a sealing state to an unsealing state for shifting the injection device (100) into a ready-to-administer state.

Abstract: The present invention relates to injection devices for injecting a dose of a medicament. The injection device (100) incorporates a housing (101), a needle assembly (150) and a cover (200). The needle assembly (150) comprises an injection needle (152, 153) accommodated in a needle container (151) having an opening which in a storage state of the injection device (100) is sealed by a film seal (155). The cover may include sections (201, 202) arranged movable relative to the housing (101). The injection device (100) is so configured that upon movement of the cover sections (201, 202) relative to the housing (101) the film seal (155) is changed from a sealing state to an unsealing state for shifting the injection device (100) into a ready-to-administer state.

Abstract: Drug delivery system comprising a cartridge with an axially displaceable piston, and a front-loaded cartridge holder adapted to axially receive and hold a cartridge in a loaded position. The cartridge comprises first coupling means arranged at the distal portion, and the cartridge holder comprises second coupling means arranged at the distal portion, wherein the first and second coupling means are configured to engage each other to thereby axially secure a cartridge mounted in the cartridge holder.

Abstract: The present invention relates to injection devices for injecting a dose of a medicament. The injection device (100) incorporates a housing (101), a needle assembly (150) and a cover (200). The needle assembly (150) comprises an injection needle (152, 153) accommodated in a needle container (151) having an opening which in a storage state of the injection device (100) is sealed by a film seal (155). The cover may include sections (201, 202) arranged movable relative to the housing (101). The injection device (100) is so configured that upon movement of the cover sections (201, 202) relative to the housing (101) the film seal (155) is changed from a sealing state to an unsealing state for shifting the injection device (100) into a ready-to-administer state.

Abstract: The present invention relates to medicament injection devices (100). A cartridge (600) with a septum and a needle unit (500) having front and rear needles (510, 520) are configured for relative movement from a state where the septum is sealed to a state where the septum is pierced by the rear needle (520). The injection device (100) may include a needle shield (350) and be configured for piercing the septum by the rear needle (520) when the front needle (510) is operated relative to the needle shield (350). The injection device (100) may also include a damping mechanism configured for limiting the speed of movement of the cartridge relative to the needle unit. The injection device (100) may also include an indicator generating a signal when a piston driver has travelled the complete stroke length, wherein the indicator has a deflection element that is deflected prior to or during movement of the cartridge relative to the housing.