Abstract: This invention provides 1-substituted-7-azabicyclo[2.2.1]heptyl derivatives, intermediates and methods for producing them, which are therapeutic agents useful for the prevention and treatment of central nervous system disorders and diseases mediated by a Nicotinic Acetylcholine Receptor such as Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy, pain, nicotine addiction and dementia.

Abstract: The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

Abstract: Disclosed are glucoside alkyl urethanes composed of units of the formula: A(O—CO—NH—R)s wherein A represents a glucosyl unit of a starch hydrolysate moldecule, the starch hydrolysate having a Dextrose Equivalent (D.E.) ranging from 1 to 47, (O—CO—NH—R) represents an N-alkyl aminocarbonyloxy group replacing a hydroxyl group of the glucosyl unit A, and wherein R represents a linear or branched, saturated or unsaturated alkyl group containing from 3 to 22 carbon atoms, and s represents the number of alkyl carbamate groups per glucosyl unit which number is expressed as degree of substitution (DS) with said DS value ranging from about 0.01 to about 2.0 which are useful as surface-active agents. Also disclosed are a method for their manufacture and to compositions containing one or more glucoside alkyl urethanes.

Abstract: The invention relates to the use as surfactant, for the preparation of dispersions of multiphase systems that comprise a continuous aqueous phase containing a high concentration of electrolytes, of hydrophobically modified saccharides of general formula (I) and (II) [A]n(-M)s (I) [B]m(-M)s? (II) wherein [A]n represents a fructan-type saccharide [B]m represents a starch-type saccharide (-M) represents a hydrophobic moiety that substitutes a hydrogen atom of a hydroxyl group of the fructosyl and/or glucosyl units of the fructan-type and starch-type saccharides, which is selected from the group consisting of an alkylcarbamoyl radical of formula R—NH—CO— and an alkylcarbonyl radical of formula R—CO—, wherein R represents a linear or branched, saturated or unsaturated alkyl group with from 4 to 32 carbon atoms, and s and s?, which can have the same value or not, represent the number of said hydrophobic moieties that substitute the fructosyl or glucosyl unit, expressed as average degree of substitution (av.

Abstract: In a tubular skylight, an Aluminum sheet having corrugations that may be in a waffle pattern is formed with a hole that is pressed into a curb which is fastened over the turret of a roof-mounted skylight flashing. Roof tiles above the dome of the skylight are placed onto the sheet, while below the dome the sheet is placed over roof tiles and manually conformed thereto, owing to the corrugations. Any water that leaks past tiles above the dome will be directed by the sheet around the curb and down onto the tops of tiles that are below the dome, thereby providing a water seal for the skylight. Clips can be used to hold the lower edge of the sheet onto the tiles.

Abstract: In a tubular skylight, a corrugated Aluminum sheet is formed with a hole that is pressed into a curb which is fastened over the turret of a roof-mounted skylight flashing. Roof tiles above the dome of the skylight are placed onto the sheet, while below the dome the sheet is placed over roof tiles and manually conformed thereto, owing to the corrugations. Any water that leaks past tiles above the dome will be directed by the sheet around the curb and down onto the tops of tiles that are below the dome, thereby providing a water seal for the skylight.

Abstract: In a tubular skylight, a corrugated Aluminum sheet is formed with a hole that is pressed into a curb which is fastened over the turret of a roof-mounted skylight flashing. Roof tiles above the dome of the skylight are placed onto the sheet, while below the dome the sheet is placed over roof tiles and manually conformed thereto, owing to the corrugations. Any water that leaks past tiles above the dome will be directed by the sheet around the curb and down onto the tops of tiles that are below the dome, thereby providing a water seal for the skylight.

Abstract: In a tubular skylight, an Aluminum sheet having corrugations that may be in a waffle pattern is formed with a hole that is pressed into a curb which is fastened over the turret of a roof-mounted skylight flashing. Roof tiles above the dome of the skylight are placed onto the sheet, while below the dome the sheet is placed over roof tiles and manually conformed thereto, owing to the corrugations. Any water that leaks past tiles above the dome will be directed by the sheet around the curb and down onto the tops of tiles that are below the dome, thereby providing a water seal for the skylight. Clips can be used to hold the lower edge of the sheet onto the tiles.

Abstract: A valve for selectively blocking the light passageway of a skylight includes a cylindrical shroud and first and second semicircular butterfly valve elements that pivot on respective axles within the shroud to selectively block the skylight. The axles can ride on a common motor-driven cam between a horizontal orientation to block the skylight and a vertical orientation to allow light to pass. The motor can be powered by a universal power supply that can operate at anywhere from below 100 volts to above 270 volts.