Abstract: The present invention is related to agents capable of binding to and inhibiting or antagonizing the action of IL-11 and/or or IL-11RA for the treatment and/or prevention of abnormal uterine bleeding, which comprises heavy menstrual bleeding, prolonged bleeding, altered bleeding pattern, dysmenorrhea, as well as of the underlying diseases leiomyoma and endometriosis and the use of the agent to inhibit menstruation. Furthermore, the invention provides novel IL-11 antibodies.

Abstract: A method for determining a concentration of a target gas in blood of a human or animal animate being. The method includes the steps of: generating electromagnetic excitation radiation having a carrier frequency, wherein the carrier frequency is selected such that the target gas and an absorbing gas absorb the excitation radiation, modulating an amplitude or the carrier frequency of the excitation radiation with a modulation frequency, illuminating an absorption path superficial to a skin of the animate being with the excitation radiation, generating a sound wave by an absorption of the excitation radiation in the absorption gas, and detecting at least one of an amplitude and a phase of the sound wave as a measure of a concentration of the target gas on the absorption path. Also provided is a photoacoustic sensor for determining a concentration of a target gas in blood of a human or animal animate being.

Abstract: The disclosure relates to a diffusor for a gas generator of an airbag module, comprising a substantially tubular base body with a longitudinal axis, a baffle cap axially connected to the base body at a first end of the diffusor and a connecting device configured at a second end of the diffusor opposite to the first end. At least one outflow opening is formed in an outer wall of the tubular base body such that gas can flow out of an interior of the diffusor substantially in parallel to a longitudinal axis in the direction of the first end and the second end from the diffusor. The baffle cap is free from an outflow opening. The disclosure further relates to a gas generator comprising such a diffusor, as well as an airbag module including such a gas generator. Moreover, a method for manufacturing the diffusor is also proved.

Abstract: A method including providing an acoustic resonator having an absorption element with a surface portion, providing a sample fluid or a fluid mixture containing the sample fluid with at least one absorption fluid or particles such that the acoustic resonator is filled with the same, the surface portion of the absorption element being in contact with the sample fluid. Irradiating the surface portion of the absorption element with a first electromagnetic radiation such that the absorption element at least partly absorbs the first electromagnetic radiation in the region of the surface portion, or irradiating the fluid mixture with a first electromagnetic radiation such that the absorption fluid or the absorption particles at least partly absorb(s) the first electromagnetic radiation, and so, by way of the absorption, pressure energy is generated in the sample fluid or the fluid mixture, with the first electromagnetic radiation being amplitude modulated or frequency modulated with a modulation frequency.

Abstract: An elevator installation erection method includes installing in an elevator shaft: a construction phase elevator system having a self-propelled elevator car whose usable lifting height is adapted to an increasing elevator shaft height; at least one guide rail in the elevator shaft guiding the elevator car along its travel path; and a drive system driving the elevator car and including a primary part attached to the elevator car and a secondary part attached along the elevator car travel path, wherein the guide rail and the secondary part are gradually extended upwards during the construction phase, wherein the self-propelled elevator car transports persons and/or material for the construction of the building and passengers and freight for floors already used as residential or business premises, and wherein after the elevator shaft has reached its final height the construction phase elevator system is replaced by a final elevator system.

Abstract: The present invention relates to a process for the separation of propylene from a gas mixture (GM) comprising propylene and propane by means of a membrane (M) comprising a polyarylene ether sulfone polymer (P) prepared by converting a reaction mixture (RG) comprising at least one aromatic dihalogen sulfone and at least one dihydroxy component comprising trimethylhydroquinone.

Abstract: The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer, said method comprising: (a) determining in a tumor sample from said patient the RNA expression levels of at least 2 of the following 9 genes: UBE2C, BIRC5, RACGAP1, DHCR7, STC2, AZGP1, RBBP8, IL6ST, and MGP (b) mathematically combining expression level values for the genes of the said set which values were determined in the tumor sample to yield a combined score, wherein said combined score is indicative of a prognosis of said patient; and kits and systems for performing said method.

Abstract: A method for teaching an electronic computing device includes at least a machine learning algorithm for predicting a position-based propagation of radio waves in an environment, including the steps of: providing a mathematical model for the position-based propagation, wherein the mathematical model includes at least a physical model for the position-based propagation in the environment generating training data for the machine learning algorithm including a propagation field and/or a propagation domain; training the machine learning algorithm by fitting the training data to a partial derivative of the machine learning algorithm; and obtaining a prediction of a propagation loss by a weighted sum of multiple evaluations of the trained machine learning algorithm. Furthermore, provided is a computer program product, a computer-readable storage medium as well as an electronic computing device.

Abstract: The present invention relates to the medical use of a zwitterionic antifouling hydrogel. The hydrogel may be used in prevention of and protection against inflammation of tissue or in stabilization of a tissue implant.

Abstract: A method and a device for the detection of transglutaminases, in particularly of blood coagulation factor XIII (FXIII). The method is based on a rapid, point-of-care compatible test principle for transglutaminases and allows an exact determination of FXIII in a short time and with simple handling.

Abstract: Method and apparatus for industrial scale production of a suspension for a battery, wherein an input material is processed via ball milling in a rotating chamber of a device that is effected as a continuous process with a continuously controlled addition of the input material and with a continuously controlled delivery of the processed output material, where state parameters of the input material and process parameters of the manufacturing installation are acquired as first parameters during production of the suspension, results of laboratory analyses about the state or quality of the manufactured suspension are acquired as second parameters in a learning phase during production, the first and the second parameters are used in the learning phase for training a model for predicting the state or quality via machine learning, and where the device is open-loop or closed-loop controlled outside the learning phase via the first parameters and the trained model.

Abstract: Systems and methods involving implants positioned within implant pockets through minimally invasive entrance incisions, along with related neurostimulatory implants. In some implementations, implants may be folded, rolled, or otherwise compressed to fit within subcutaneous implant pockets, after which they may be decompressed to fit within an implant pocket having one or more dimensions substantially larger than the entrance incision. Such implants may be used for a variety of purposes, including generating electrical energy for various other implants, including neurostimulatory implants located throughout the body.

Abstract: The present disclosure provides a computer implemented method for facilitating a teaching surgeon to teach or assist a learning surgeon in minimally invasive interventions using a surgical instrument including displaying endoscopic images of an intervention site in real time on a display device, said endoscopic images being captured using a camera associated with an endoscopic instrument, and tracking a movement of one or both hands of said teaching surgeon and/or a device held by said teaching surgeon, using a real-time tracking apparatus, wherein said real-time tracking apparatus comprises a tracking system and a computing device, wherein said tracking of said movement comprises recording a sequence of tracking information of one or both hands of said teaching surgeon and/or the device held by said teaching surgeon.

Abstract: A controller for a technical system is trained using a machine learning method. For this purpose, a chronological sequence of training data is detected for the machine learning method, the training data including both state data as well as control action data of the technical system. A change in the control action data over time is detected specifically and correlated with changes in the state data over time within different time windows, wherein a time window specific correlation value is ascertained in each case. A resulting time window is then ascertained on the basis of the ascertained correlation values, and the training data which is found within the resulting time window is extracted in a time window-specific manner. The controller is trained by means of the machine learning method using the extracted training data and thereby configured to control the technical system.

Abstract: Provided is an apparatus and method for cooperative controlling wind turbines of a wind farm, wherein the wind farm includes at least one pair of turbines aligned along a common axis approximately parallel to a current wind direction and having an upstream turbine and a downstream turbine. The method includes the steps of: a) providing a data driven model trained with a machine learning method and stored in a database, b) determining a decision parameter for controlling at least one of the upstream turbine and the downstream turbine by feeding the data driven model with the current power production of the upstream turbine which returns a prediction value indicating whether the downstream turbine will be affected by wake, and/or the temporal evolvement of the current power production of the upstream turbine; c) based on the decision parameter, determining control parameters for the upstream turbine and/or the downstream turbine.

Abstract: A computer-implemented method for determining at least one remaining time value, to be determined, for a system is provided, having the following steps: a. providing at least one known input data record containing a multiplicity of input elements for at least one determined time; b. providing at least one associated known remaining time value for the at least one input data record; c. determining the at least one remaining time value to be determined by applying an error function to the at least one input data record and the at least one associated remaining time value; and d. providing an output data record containing the at least one determined remaining time value and an associated reliability value. The invention furthermore targets a corresponding determination unit and computer program product.

Abstract: Real state information, which influences the switching times of a light signal system, is supplied as input signals to a first neural network in a fixed time cycle. The first neural network calculates estimated state information as a replacement for real state information or parts of the real state information which are not received in good time or are received incorrectly in the fixed time cycle. This estimated state information is output to artificial intelligence which predicts the switching times. The first neural network allows the artificial intelligence to also make good predictions for the switching times of signal groups when one of the many communication paths involved fails or is overloaded. It is therefore possible to predict signal group states in the fixed time cycle in real time with a high degree of robustness and tolerance with respect to gaps in the time cycle of the real state information provided.

Abstract: Various embodiments include a method for producing a quality test system executing a quality test model with a filter mask and a quality model to determine a quality feature of a battery cell. The system has an electrochemical impedance spectroscopic unit for capturing test data relating to the battery within a frequency range. The method includes: creating the model; and producing the system. Creating the model includes: capturing spectroscopic learning data; creating the filter mask using a first machine learning method with analysis data from part of the frequency range by consulting the filter mask and creating the model using a second machine learning method. The first and the second learning method are coupled based on the learning data. The first machine learning method creates a filter mask determining the analysis data such that the second machine learning method creates a quality model optimized with respect to maximizing the quality.

Abstract: Various embodiments include a sensor module for providing a sensor module signal comprising information representative of a physical quantity measured by the sensor module. The sensor module may include: a first sensor providing a signal representative of the physical quantity; a first processing device processing the first signal; a second sensor providing a signal representative of the physical quantity; a second processing device processing the second signal; a control device generating the sensor module signal based on the processed first sensor signal and the processed second sensor signal; and a checking device checking the sensor module signal, the processed first sensor signal, and the processed second sensor signal for coherency, and providing a check result signal representative of a result of the check.

Abstract: The invention is directed to a vehicle pneumatic tire wherein strengthening plies are provided with steel cords running parallel to one another. The belt plies can be used, as isolated electrically conductive plates, for supplying electricity to electrical consumers such as sensors and actuators installed in the tire. Adjacent belt plies can be connected by puncture sensors to be able to identify damage to the belt caused by metallic parts penetrating from the outside, such as nails, on the basis of a change in the electrical resistance.