Abstract: A phantom device for in-vitro validation of radiation procedures under motion influence in consideration of an effective biological dose includes a phantom having a first biological detector with a first biological sample. The first biological sample includes a plurality of culturing and irradiation elements. Each of the culturing and irradiation elements are provided with a respective biological sub-sample so that the first biological detector is configured as a spatially resolving biological detector. A first motion device is configured to move the first biological detector so as to simulate a motion of a target volume.

Abstract: A method for irradiating a target volume includes defining a target region having a plurality of target points. The target points are individually approachable. The method includes defining a number of rescanning passes, in which the target region is scanned multiple times, such that the plurality of target points of the target region is approached variously often during the rescanning passes. At least some target points of the plurality of target points are not approached in all of the rescanning passes. The approaching of the plurality of target points is distributed among the rescanning passes such that for a target point of the plurality of target points that is not approached in all of the rescanning passes, at least one further rescanning pass, in which the target point is not approached, is located before a final rescanning pass, in which the target point is approached.

Abstract: To control of an irradiation installation, a particle beam is generated with a beam intensity, and a beam quality of the particle beam is monitored with a beam monitoring device. One of several adjustable measurement ranges is selected, wherein the measurement range of the beam monitoring device is set depending on the beam intensity of the particle beam and/or depending on a particle count to be applied.

Abstract: The invention relates to an apparatus for evaluating an activity distribution obtained in a moved target object by a beam that is generated by an irradiation device. Said apparatus comprises: a positron emission tomograph designed to record photons generated in the target object by the beam and generate measurement data representing points of origin of the photons; a movement detection device designed to generate a movement signal representing the movement of the target object; and an evaluation unit designed to associate the points of origin of the measured photons with positions in the target object with the help of the movement signal such that three-dimensional characteristics of the activity distribution actually generated in the target object can be evaluated by means of the photons generated by the beam. The invention further relates to an irradiation system and a method in which such an apparatus is used.

Abstract: A method of generating a data set defining a plurality of target points in a target volume in a body at which a particle beam is to be directed in a continuous or discontinuous process includes directing a particle beam to each of the target points so as to provide a spatial dose distribution in an area around the respective target point. The target points include a first target point having z-spacing, measured in a direction of the particle beam in a homogenous body equivalent to the body, from an adjacent second target point at a higher or lower particle energy. The method also includes defining the target points in the data set by at least one of the z-spacing and the spatial dose distribution in dependence upon a particle energy of the respective target point.

Abstract: A method for drawing up an irradiation plan includes at least one of calculating, assessing, displaying and taking into consideration effects of at least one uncertainty on the irradiation plan, at least one of at times and in certain areas.

Abstract: A radiation phantom device includes at least one movement device for moving at least one first sub-region of the radiation phantom device. The radiation phantom device has at least one of at times or in regions, radiation properties which are in conformity with a radiation phantom model.

Abstract: The invention concerns an idea of planning irradiation of two target points (81, 9) with a beam approaching target points (72) for the purpose of depositing a first target dose distribution in a first of the two target volumes (81, 92) and a second target dose distribution in a second of the two target volumes (81, 92). The idea is characterized by the following steps: assigning target points (72) to one of the target volumes (81, 92), detecting an overlap of a first deposition caused by approaching a target point (72) assigned to the first target volume (81, 92) with a second deposition caused by approaching a target point (72) assigned to the second target volume (81, 92), and adapting the planning process for at least one of the target points (72) whose approach contributes to the overlap of the first and second deposition.

Abstract: A method for drawing up an irradiation plan for a radiation-generating device that includes a plurality of irradiation positions that, at least one of partially or at times, correlate with at least one basic parameter that is present at a point in time of the implementation of the irradiation plan, includes giving greater consideration to correlations with the at least one basic parameter that are expected with greater probability for at least some of the irradiation positions.

Abstract: The invention concerns a method for irradiating a target with a beam approaching target points, involving the following steps: Measuring at least one of the parameters relating to the position of the beam and the intensity of the beam, changing the beam as a function of the at least one measured parameter, particularly as a function of a variance relating to the at least one measured parameter. The method is characterized in that the at least one measured parameter is measured at the most once per target point. Furthermore, the invention concerns a device for irradiating a target in accordance with the invention-based method and a control system for controlling such a device.

Abstract: A method of determining an actual, especially an actual effective, radiation dose distribution of a moving target volume includes detecting first and further positions of volume elements of the target volume in a first and at least one further motional state of the moving target volume, determining transformation parameters by transformation of the first positions into the further positions, irradiating the moving target volume in accordance with an irradiation plan which comprises a plurality of raster points to be irradiated, wherein during the irradiation of a raster point it is detected which of the motional states is occupied by the moving target volume, assigning raster points to subirradiation plans and determining the actual effective dose for each of the plurality of volume elements, in each case from contributions from the raster points of the subirradiation plans using the transformation parameters.

Abstract: The invention concerns a device for determining control parameters for an irradiation system by means of which a number of irradiation doses are successively deposited at different target points in a target volume.

Abstract: The invention relates to a method for checking an irradiation installation in which a dose distribution is deposited in a target object by means of a treatment beam, said method comprising the following steps: an irradiation planning data record optimised for the irradiation of a moving target volume is provided; a movement signal that reproduces a movement of the target volume is provided; a phantom is irradiated, said phantom being formed for detecting a dose distribution deposited in the phantom during or after the irradiation, using the control parameters stored at the irradiation planning data record and the movement signal; a dose distribution deposited in the phantom is determined; a dose distribution to be expected is calculated on the basis of parameters that are related to the control of the irradiation installation during the irradiation; and the determined dose distribution deposited in the phantom is compared to the calculated dose distribution to be expected.

Abstract: A control parameter is determined for a system for irradiating a predetermined target volume in a body with a particle beam. The system is constructed to direct the particle beam at a multiplicity of target points in the target volume in succession in order to produce at, each of the target points a predetermined dose distribution in a region around the target point. The control parameter controls the extent of an overlap of the dose distribution of a first target point with the dose distributions of neighboring target points. For determination of the control parameter, there is first determined a movement parameter which quantitatively characterizes the movement of the body at the first target point. The control parameter is determined in dependence on the movement parameter.

Abstract: A method actuates a device for irradiating an object that has at least one target volume to be irradiated and at least one volume to be protected. The method includes defining at least one signal dose value for the volume to be protected and irradiating the object at least one of at least at times and at least in part with hadron irradiation. A dose introduced into the volume to be protected during the irradiation of the object is determined and at least one signal is emitted as soon as the introduced dose exceeds at least one signal dose value in at least one point of the volume to be protected.

Abstract: A method for controlling dosage application during irradiation of a moveable target volume in a body with an energy beam by scanning the target volume includes, before irradiating an i-th grid position, determining a dosage during the irradiation process using the movement data, wherein the dosage already contains the i-th grid position during irradiation of the previous grid positions (1<=k<i). Depending on the determined dosage that already contains the i-th grid position during the irradiation of the previous grid positions (1<=k<i), a compensation value for the i-th grid position is calculated, and depending on the compensation value and on the nominal particle fluence for the i-th grid position, a compensated particle fluence (Fikomp) is calculated for the i-th grid position in order to irradiate the i-th grid position with the compensated particle fluence (Fikomp).

Abstract: A method for irradiating a target volume includes defining a target region having a plurality of target points. The target points are individually approachable. The method includes defining a number of rescanning passes, in which the target region is scanned multiple times, such that the plurality of target points of the target region is approached variously often during the rescanning passes. At least some target points of the plurality of target points are not approached in all of the rescanning passes. The approaching of the plurality of target points is distributed among the rescanning passes such that for a target point of the plurality of target points that is not approached in all of the rescanning passes, at least one further rescanning pass, in which the target point is not approached, is located before a final rescanning pass, in which the target point is approached.

Abstract: The present embodiments relate to a device for controlling an irradiation system for irradiating a moving target volume. The device includes an evaluation device for evaluating a substitute movement signal. The device also includes an imaging device for recording image data of the moving target volume. The imaging device is activated or deactivated by a control device according to the evaluation of the substitute movement signal. The device includes an image evaluation device for evaluating the image data recorded by the imaging device, and an irradiation device that is activated or deactivated using an irradiation control device according to the evaluation of the image data.

Abstract: A system for irradiating a predetermined target volume in a body with a particle beam is constructed to direct the particle beam at a multiplicity of target points in the body in succession, in order to produce at each of the target points a predetermined dose distribution. For the system there is determined a planning target volume by first determining, in a fictive homogeneous body, a target volume equivalent to the minimum target volume in the body. The equivalent target volume is extended by a safety margin, in order to determine the planning target volume.

Abstract: The invention relates to an apparatus for evaluating an activity distribution obtained in a moved target object by a beam that is generated by an irradiation device. Said apparatus comprises: a positron emission tomograph designed to record photons generated in the target object by the beam and generate measurement data representing points of origin of the photons; a movement detection device designed to generate a movement signal representing the movement of the target object; and an evaluation unit designed to associate the points of origin of the measured photons with positions in the target object with the help of the movement signal such that three-dimensional characteristics of the activity distribution actually generated in the target object can be evaluated by means of the photons generated by the beam. The invention further relates to an irradiation system and a method in which such an apparatus is used.