Abstract: A 3D camera uses a modulated visible light source for depth imaging and includes a processor operable to perform time multiplexing between image detection and depth or time-of-flight (ToF) detection using the same photodetectors. The camera can alternate between the image detection mode and the ToF detection mode to produce a continuous stream of color and depth images that can be overlaid without the need for any post-processing software. The camera can also be configured to determine time-of-flight using analog integration modules, thereby minimizing the circuitry necessary for analog-to-digital conversions and ToF calculations in the digital domain.

Abstract: A water reservoir for an apparatus for humidifying a flow of breathable gas includes a reservoir base including a cavity structured to hold a volume of liquid and a conductive portion provided to the base. The conductive portion is adapted to thermally engage with a heater plate to allow thermal transfer of heat from the heater plate to the volume of liquid. The conductive portion includes a thin film comprising a non-metallic material, and the thin film includes a wall thickness less than about 1 mm.

Abstract: Closed-loop systems and methods for controlling pH. The system includes a working electrode, a counter electrode, a reference electrode, a first ion-sensitive field-effect transistor (ISFET), a second ISFET, and an electronic controller. The working electrode, the counter electrode, the reference electrode, and a first sensing terminal of the first ISFET are immersible in an active solution. A second sensing terminal of the second ISFET is immersible in a reference solution. The electronic controller is configured to apply a first amount of current or voltage to the working electrode and determine a differential voltage between the first ISFET and the second ISFET. The electronic controller is also configured to set a second amount of current or voltage to reduce a difference between the differential voltage and a target voltage. The electronic controller is further configured to apply the second amount of current or voltage to the working electrode.

Abstract: An electromagnetic force-compensation direct measuring system (100) has a load receiver (101), which is connected to a force-compensation device (120) via a power-transmission linkage. The system has a multipart parallel guide mechanism, which has at least two parallel-guiding members (131, 132) spaced apart by the power-transmission linkage. The force-compensation device has at least one permanent magnet (121) and a coil (122) electrically connected to a controllable electrical circuit. At least one parallel-guiding member is electrically integrated in the controllable electrical circuit. The power-transmission linkage is designed as a single-part coil body (110) such that the coil is arranged on the coil body between the parallel-guiding members and is electrically connected to the controllable electrical circuit.

Abstract: A method for detecting an amount of an analyte in a solution includes adding an electrochemically active agent to the solution; applying an electrical current to a working electrode in contact with the solution to initiate the electrochemical redox reaction to change a pH of the solution from a first pH value to a second pH value; incubating the solution at the second pH value to allow the analyte to dissociate from the other molecules in the solution and to bind to a capture molecule connected to the working electrode via a linker; reacting a detecting probe with the analyte to allow the detecting probe to bind to the analyte, the detecting probe having a signaling tag attached thereto and configured to produce a signal at the second pH value; and collecting the signal to calculate the amount of the analyte in the solution.

Abstract: A system and method of quantitating the concentration of a molecule of interest in one embodiment includes establishing a plurality of test environments at a plurality of test sites, each of the plurality of test environments associated with one of a plurality of response curves, each of the plurality of response curves different from the other of the plurality of response curves, storing a combined response curve resulting from a summation of the plurality of response curves, exposing the plurality of test sites to a sample having a concentration of a molecule of interest, obtaining a plurality of quantitation signals, each of the plurality of quantitation signals associated with one of the plurality of test sites, associating a summation of the plurality of quantitation signals with the stored combined response curve, and generating a signal related to the concentration of the molecule of interest based upon the association.

Abstract: A 3D camera uses a modulated visible light source for depth imaging and includes a processor operable to perform time multiplexing between image detection and depth or time-of-flight (ToF) detection using the same photodetectors. The camera can alternate between the image detection mode and the ToF detection mode to produce a continuous stream of color and depth images that can be overlaid without the need for any post-processing software. The camera is configured to determine time-of-flight using analog integration modules, thereby minimizing the circuitry necessary for analog-to-digital conversions and ToF calculations in the digital domain.

Abstract: A device to electrochemically sequence DNA that includes a redox species includes at least one edge electrode, at least one stack of insulator material, and a pair of DNA translocation electrodes including a DNA translocation working electrode and a DNA translocation counter electrode, where the thickness of the at least one edge electrode is about 0.5 nanometers, and the thickness of the at least one stack of insulator material is about 10 nanometers. Methods of electrochemically sequencing a strand of DNA are also provided.

Abstract: The present technology relates to a pad for forming a seal forming structure against a user's skin for use with a patient interface, the pad comprising, a base layer, a fibre layer comprising a plurality of fibers for contacting a patient's skin, and a connection layer for connecting the fibers to the base material, wherein the base layer and/or the fibre layer is/are adapted to act as a reservoir for substances. Furthermore, it relates to a set of pads, a kit and a patient interface.

Abstract: The invention relates to a patient ventilation or breathing device and components therefore for use in all forms of respiratory apparatus ventilation systems including invasive and non-invasive ventilation, positive airway pressure therapy, Continuous Positive Airway Pressure (CPAP), and particularly Bi-Level therapy and treatment for sleep disordered breathing (SDB) conditions such as Obstructive Sleep Apnea (OSA), and for various other respiratory disorders and diseases. The invention particularly relates to a blower, to a blade, to a gasket, to a cable, to an impeller, to a gas inlet and inlet member, to an improved air path or fluid flow path and components thereof, and/or to a modular ventilation or breathing device as referred to above and particularly incorporating one or more of the other aspects of the invention.

Abstract: A blower for a respiratory apparatus includes an impeller configured to rotate to pressurize the supply of gas. The impeller includes a shroud with a plurality of vanes extending from a surface of the shroud toward the gas inlet. Each vane radiates outwards from a hub in the shroud that is configured to receive a motor shaft. The outer diameter of the shroud varies between maximum portions with a maximum outer diameter and minimum portions with a minimum outer diameter. The maximum portions are located at the vanes and the minimum portions are located between the vanes. In addition, each vane has an intermediate point located a predetermined distance from the hub that marks the beginning of a curvature of the vane in the direction of the impeller's rotation. The curvature of the vane is located between the intermediate point and the radially outermost end of the vane.

Abstract: The present technology relates to a pad for forming a seal forming structure against a user's skin for use with a patient interface, the pad comprising, a base layer, a fibre layer comprising a plurality of fibers for contacting a patient's skin, and a connection layer for connecting the fibers to the base material, wherein the base layer and/or the fibre layer is/are adapted to act as a reservoir for substances. Furthermore, it relates to a set of pads, a kit and a patient interface.

Abstract: An apparatus to detect more than one analyte in a solution comprising at least one electrode in contact with the solution, at least two dyes including a first dye and a second dye, and an electrochemically active agent, where the solution has a pH, the electrode is configured to modulate the pH of the solution by oxidizing or reducing the electrochemically active agent, the first dye and the second dye fluoresce at different pH levels, fluorescence of the first dye is used to indicate the presence of a first analyte, and fluorescence of the second dye is used to indicate the presence of a second analyte. Methods of detecting multiple analytes in a solution are also provided.

Abstract: A 3D camera uses a modulated visible light source for depth imaging and includes a processor operable to perform time multiplexing between image detection and depth or time-of-flight (ToF) detection using the same photodetectors. The camera can alternate between the image detection mode and the ToF detection mode to produce a continuous stream of color and depth images that can be overlaid without the need for any post-processing software. The camera is configured to determine time-of-flight using analog integration modules, thereby minimizing the circuitry necessary for analog-to-digital conversions and ToF calculations in the digital domain.

Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.

Abstract: The present disclosure relates to systems, devices, and methods for nucleic acid sequencing including polynucleotide strands having a nucleotide(s) modified with a redox label(s) attached thereto or capable of receiving the modified nucleotide(s) with a redox label(s) attached thereto. The systems, devices, and methods include a dielectric member with an attached translocating protein positioned between oxidizing and reducing electrodes.

Abstract: An interleaved ring oscillator includes a first ring oscillator having n stages, and a second ring oscillator having n stages, wherein each stage includes a nth first gated inverter in the first ring oscillator and a nth second gated inverter in the second ring oscillator, such that output from the nth first gated inverter enables the nth second gated inverter, and output from the nth second gated inverter enables the nth first gated inverter.

Abstract: A phase-shifter for a light-transmitting waveguide is segmented into multiple segments that can be calibrated to the overall length of a conventional single phase-shifter. Each segment receives a control signal, which can be a single bit signal, with the phase-shift capability of the segmented phase-shifter controlled by which segment(s) receive(s) a control signal. In one implementation, a binary weighting is applied to determine segment lengths. Smaller segments can be increased in length to achieve a 2? offset of the phase shift produced by the segment while maintaining the same binary relationship among segments. In another embodiment, multiple segments of uniform lengths can be used for a single phase-shifter with each segment controlled by an n-bit signal.

Abstract: A boost converter includes a clock generator, a switching converter, a hysteretic controller, and a power tracking module. The clock generator configured to output a clock signal; The switching converter configured to operate at a frequency based on the clock signal. The hysteretic controller configured to regulate an intermediate output from the switching converter. The power tracking module configured to change a frequency control signal that is sent to the clock generator, the change in frequency is based on a current flowing into an output capacitor such that a charge time of the capacitor is minimized when the current is maximized.