Abstract: A medical treatment planning system includes a computer including a processor and memory, data stored in the memory, said data including a priori of information relating to medical conditions, medical treatments and treatment results, and treatment planning logic stored in the memory and executable by the processor. The treatment planning logic includes logic that obtains pre-treatment patient data describing the patient's medical condition, logic that analyzes the pre-treatment patient data relative to the a priori of information and, based on the analysis, formulates a first treatment plan for treating the patient, and logic that outputs the first treatment plan for evaluation by medical personnel.

Abstract: A method for planning an infusion into hepatic tissue into a patient includes: obtaining anatomical and/or physiological patient data of the patient's liver or a region of the liver; determining at least one patient parameter from the patient data; planning the infusion using the anatomical patient data, physiological patient data, and/or at least one patient parameter, wherein planning includes determining how an administered substance is distributed in the tissue and/or how the administered substance influences physiological properties of the tissue; and determining a distribution and/or effectiveness of a therapeutic agent administered with the substance or after the substance.

Abstract: A method for determining and representing possible entry and/or target areas for positioning catheters in an area on the basis of functional data and/or structural and/or anatomical data of the area, includes: indicating at least one entry area of the catheter or at least one target area of the catheter; determining at least one target area of the catheter based on the at least one indicated entry area of the catheter and taking into consideration specified catheter positioning guidelines and the functional data and/or structural and/or anatomical data of the area, or at least one entry area of the catheter based on the at least one indicated target area of the catheter and taking into consideration specified catheter positioning guidelines and the functional data and/or structural and/or anatomical data of the area; and representing the functional data and/or structural and/or anatomical data with the at least one indicated entry area and the at least one determined target area, or representing the functiona

Abstract: A multi-layered representation and/or simulation of disease dissemination that may be complemented with consideration of therapy dissemination includes the creation of a multi-layered representation system that includes two or more of the following layers: a) a disease dissemination layer; b) a therapy dissemination layer; c) an interface layer; d) a dynamization layer; e) a solution layer; and f) a display layer.

Abstract: A catheter having an outer profile which is formed such that a path length along an outer surface of the catheter is greater than the corresponding length of the catheter, and to a method for determining the shape of a catheter, and wherein the elasticity and/or conductivity of the tissue into which the catheter is to be introduced is taken into account in order to determine the outer profile of the catheter.

Abstract: A method for determining the location of electrical activity or hyperactivity of nerve cells in an anatomical structure of a body, wherein an electrical conductivity model of the anatomical structure is generated and electrical impulses are detected by at least one electrode. Using the model and the detected electrical impulses, the location or locations of the electrical activity in the anatomical structure are determined.

Abstract: A system and method for treating Alzheimer's disease by delivery of an agent within the brain. At least one image of a target region is acquired, and at least one magnetic resonance diffusion tensor imaging (MR-DTI) scan of the target region is acquired. A diffusion tensor is calculated from the at least one MR-DTI scan, and at least one of an agent distribution and an agent concentration from the images and the calculated diffusion tensor is calculated. Using at least one of the calculated diffusion tensor, the images, the calculated agent distribution, and the calculated agent concentration, the placement of a delivery instrument is planned to deliver the agent to the target region to achieve a desired agent concentration and/or agent distribution within the target region.

Abstract: A system and method for treating Amyotrophic Lateral Sclerosis (ALS) by delivery of an agent within the brain. At least one image of a target region is acquired, and at least one magnetic resonance diffusion tensor imaging (MR-DTI) scan of the target region is acquired. A diffusion tensor is calculated from the at least one MR-DTI scan, and at least one of an agent distribution and an agent concentration from the images and the calculated diffusion tensor is calculated. Using at least one of the calculated diffusion tensor, the images, the calculated agent distribution, and the calculated agent concentration, the placement of a delivery instrument is planned to deliver the agent to the target region to achieve a desired agent concentration and/or agent distribution within the target region.

Abstract: A system and method for treating Parkinson's disease by delivery of an agent within the brain. At least one image of a target region is acquired, and at least one magnetic resonance diffusion tensor imaging (MR-DTI) scan of the target region is acquired. A diffusion tensor is calculated from the at least one MR-DTI scan, and at least one of an agent distribution and an agent concentration from the images and the calculated diffusion tensor is calculated. Using at least one of the calculated diffusion tensor, the images, the calculated agent distribution, and the calculated agent concentration, the placement of a delivery instrument is planned to deliver the agent to the target region to achieve a desired agent concentration and/or agent distribution within the target region. Delivery of the agent can be coordinated with an applied electrical stimulation.

Abstract: A method for planning to treat tissue by administering a substance which emits energy or can interact with administered energy to a body, such as body tissue, wherein a dispersion of the substance in the body is simulated, and to a system or device for planning administering a substance and administering energy to a body or in body tissue.

Abstract: The visualization of procedural guidelines for a medical procedure, in which a medical instrument is shown in an image representation of a body portion including an area in which a medical procedure is to be carried out, wherein, in the vicinity of the functional portion of the instrument, regions or locations are indicated which are of special relevance to the procedure according to established guidelines for said procedure.

Abstract: This document discusses, among other things, systems, devices, and methods that include a hollow-tube stylet shaped and sized for insertion into a flexible infusion catheter for use as a guiding stylet during insertion of the stylet and catheter toward a subject. Fluid is loaded into the hollow tube stylet, and released upon withdrawal of the stylet from the infusion catheter. This avoids air from occupying the infusion catheter upon withdrawal of the stylet, which could disturb the infusion of the agent.

Abstract: A method for identifying advantageous and non-advantageous infusion regions in the tissue includes capturing at least one of (i) functional anatomical data and (ii) structural anatomical data. The captured anatomical data is evaluated with computer assistance. Based on the evaluating step, the method includes determining infusion distribution information, such as directional and velocity information.

Abstract: A method for positioning at least one catheter on a body in which a fluid is present includes performing a body-specific detection of anatomical structure and/or tissue structure. A position of the fluid in the body and/or the amount of fluid in the body are detected and at least one catheter is positioned such that at least a part of the fluid can be drained from the body. A method for simulating drainage of a fluid from an interstice of a body includes performing a body-specific detection of anatomical structure and/or tissue structure. A position of the fluid in the body and/or the amount of fluid in the body are detected and a location of at least one catheter on the body is set.

Abstract: A method for determining migration pathways of cells includes capturing data on a body using an imaging method. Information relevant to migration pathways is obtained from the captured data and migration pathways are individually calculated for said body. A device for determining migration pathways of cells includes a device for carrying out an imaging method and an evaluation unit for individually ascertaining migration pathways in a body, based on the data provided by the device.

Abstract: The present invention relates to: a method for planning an infusion, wherein patient data are captured and the infusion to be carried out is planned using the captured patient data; and to a computer program which may be loaded in the memory of a computer and which includes sections of software code with which the method is performed when the program is running on a computer; and to a device for planning an infusion, comprising a patient data capturing system and a computer system for carrying out planning based on the captured patient data; to a method for carrying out an infusion, wherein the infusion is planned and then carried out; and to a device for carrying out an infusion, comprising a verification device for comparing planned infusion data with actual infusion data.