Patents by Inventor Christophe Carola
Christophe Carola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130261175Abstract: The present invention relates to the use of compounds of the formula (I) for the care, preservation or improvement of the general condition or appearance of the skin or hair, and to preparations comprising compounds of the formula (I).Type: ApplicationFiled: November 14, 2011Publication date: October 3, 2013Applicant: MERCK PATENT GMBHInventors: Christophe Carola, Tatjana Mueller
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Publication number: 20130115178Abstract: The invention relates to the use of alduronic acids and dialdehydes of the aldoses and derivatives thereof as tanning enhancers for dihydroxyacetone or for a mixture of self-tanning substances comprising dihydroxyacetone or as self-tanning substance. The invention furthermore relates to the use thereof for modulation of the hue achieved in the case of tanning with dihydroxyacetone or by the mixture or preparation comprising dihydroxyacetone. The invention furthermore relates to the use thereof as contrast reduction agent in a mixture or preparation comprising at least dihydroxyacetone as self-tanning substance. The use of such compounds enables a significantly improved colouring result of the skin.Type: ApplicationFiled: June 24, 2011Publication date: May 9, 2013Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNGInventors: Valerie Bicard-Benhamou, Christophe Carola
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Patent number: 8052963Abstract: The present invention relates to compounds of the formula (I), where R1 to R3 each, independently of one another, denote H, hydroxyl or alkoxy having 1 to 8 C atoms, R4 denotes alkyl having 1 to 4 C atoms, H, hydroxyl or alkoxy having 1 to 8 C atoms, R5 denotes H or hydroxyl, and R6 denotes H or alkyl having 1 to 18 C atoms, or salts thereof, but where all R1 to R4 together cannot be equal to H, to compositions, and to the preparation and use thereof.Type: GrantFiled: October 4, 2007Date of Patent: November 8, 2011Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Christophe Carola, Herwig Buchholz
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Patent number: 7943662Abstract: The invention relates to complexes of certain flavonoid derivatives, of the formula (I), where R1 and R2 are selected from H and OR11, where OR11 stands, independently of one another, for OH, straight-chain or branched C1- to C20-alkoxy groups, straight-chain or branched C3- to C20-alkenyloxy groups, straight-chain or branched C1- to C20-hydroxyalkoxy groups, where the hydroxyl group(s) may be bonded to a primary or secondary carbon atom in the chain and furthermore the alkyl chain may also be interrupted by oxygen, and/or C3- to C10-cycloalkoxy groups and/or C3- to C12-cycloalkenyloxy groups, where the rings may in each case also be bridged by —(CH2)n— groups, where n=1 to 3, and/or mono- and/or oligoglycosyl radicals, with the proviso that at least one radical from R1 and R2 stands for OR11, and R3 to R10 may be identical or different and stand, independently of one another, for radicals which are substantially inert with respect to the UV properties, to compositions which comprise such complexes, to corresType: GrantFiled: November 3, 2005Date of Patent: May 17, 2011Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventors: Christophe Carola, Anne Toullec, Herwig Buchholz
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Patent number: 7867993Abstract: The invention relates to novel compositions, in particular cosmetic and/or pharmaceutical compositions or food supplements, comprising at least one oxidized flavonoid derivative of the formula I, to novel oxidized flavonoid derivatives, and to novel uses of the oxidized flavonoid derivatives.Type: GrantFiled: November 2, 2005Date of Patent: January 11, 2011Assignee: Merck Patent GmbHInventors: Christophe Carola, Sylvia Huber, Herwig Buchholz
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Patent number: 7863478Abstract: The invention relates to compounds of the formula (I) or (II), to compositions which comprise such compounds, to corresponding processes for the preparation of the compounds or the compositions comprising same, and to the use thereof as light-protection filters.Type: GrantFiled: July 27, 2005Date of Patent: January 4, 2011Assignee: Merck Patent GmbHInventors: Christophe Carola, Frank Pfluecker, Herwig Buchholz, Hansjürgen Driller, Hans Neunhoeffer, Evgeniy V. Blyumin
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Patent number: 7772265Abstract: Novel compounds of the formula I in which R, X and n are as defined herein, are inhibitors of tyrosine kinase and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.Type: GrantFiled: April 1, 2008Date of Patent: August 10, 2010Assignee: Merck Patent GmbHInventors: Teresa Mujica-Fernaud, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
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Publication number: 20100028278Abstract: The invention relates to the use of compounds of the formula (I) or of a composition comprising at least one compound of the formula (I), containing radicals as described in the claims, for the care, preservation or improvement of the general state of the skin or hair.Type: ApplicationFiled: February 21, 2008Publication date: February 4, 2010Applicant: Merck Patent Gesellschaft MIT Beschrankter HaftungInventors: Christophe Carola, Ralf Rosskopf
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Publication number: 20100004209Abstract: The present invention relates to compounds of the formula (I), where R1 to each, independently of one another, denote H, hydroxyl or alkoxy having 1 to 8 C atoms, R4 denotes alkyl having 1 to 4 C atoms, H, hydroxyl or alkoxy having 1 to 8 C atoms, R5 denotes H or hydroxyl, and R6 denotes H or alkyl having 1 to 18 C atoms, or salts thereof, but where all R1 to R4 together cannot be equal to H, to compositions, and to the preparation and use thereof.Type: ApplicationFiled: October 4, 2007Publication date: January 7, 2010Applicant: MERCK PATENT GESELLSCHAFTInventors: Christophe Carola, Herwig Buchholz
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Patent number: 7588783Abstract: The invention relates to a novel flavonoid derivative, to an extract comprising the flavonoid derivative, to the cosmetic and pharmaceutical use thereof, to preparations comprising the flavonoid derivative or extract, and to a process for the preparation of the flavonoid derivative or extract.Type: GrantFiled: November 5, 2004Date of Patent: September 15, 2009Assignee: Merck Patent GmbHInventors: Herwig Buchholz, Corinna Wirth, Christophe Carola, Rosane Alves Fontes
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Publication number: 20090220438Abstract: The invention relates to the use of compounds of the formula (I), where R1 and R2 may be identical or different and stand for H, OH, OCH3, CH3, CH2OH or CH2OCH3, R3 stands for H or straight-chain or branched C1- to C20-alkyl groups, R4 stands for H or OR8, R5 and R6 may be identical or different and are selected from —H, —OH, straight-chain or branched C1 to C20-alkyl groups, straight-chain or branched C3- to C20-alkenyl groups, straight-chain or branched C1- to C20-hydroxyalkyl groups, where the hydroxyl group may be bonded to a primary or secondary carbon atom of the chain, and furthermore the allyl chain may also be interrupted by oxygen, and R8 stands for H or straight-chain or branched C1- to C20-alkyl groups, with the proviso that R2 does not denote H if R1 denotes CH3, as self-tanning agents, and to compounds and the preparation thereof.Type: ApplicationFiled: January 9, 2007Publication date: September 3, 2009Applicant: MERCK PATENT GMBHInventors: Christophe Carola, Anne Toullec, Herwig Buchholz
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Publication number: 20090209637Abstract: The invention relates to the use of chromen-4-one derivatives of the formula I where R1 and R2 may be identical or different and are selected from H, —C(?O)—R7, —C(?O)—OR7, alkyl groups, alkenyl groups, hydroxyalkyl groups and/or cycloalkyl groups and/or cycloalkenyl groups, R3 is H or alkyl groups, R4 is H or OR8, R5 and R6 are selected from —H, —OH, alkyl groups, alkenyl groups and hydroxyalkyl groups, and R7 is H, alkyl groups, a polyhydroxyl compound, such as, preferably, an ascorbic acid radical or glycosidic radicals, and R8 is H or alkyl groups, where at least two of the substituents R1, R2 and R4-R6 are different from H or at least one substituent from R1 and R2 is —C(?O)—R7 or —C(?O)—OR7, to prevent, reduce or combat signs of cellulite and/or reduce localized fatty excesses.Type: ApplicationFiled: August 30, 2006Publication date: August 20, 2009Inventors: Christophe Carola, Herwig Buchholz
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Publication number: 20080319050Abstract: The invention relates to novel compositions, in particular cosmetic and/or pharmaceutical compositions or food supplements, comprising at least one oxidised flavonoid derivative of the formula I, to novel oxidised flavonoid derivatives, and to novel uses of the oxidised flavonoid derivatives.Type: ApplicationFiled: November 2, 2005Publication date: December 25, 2008Inventors: Christophe Carola, Sylvia Huber, Herwig Buchholz
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Publication number: 20080260664Abstract: The present invention relates to particles comprising an inorganic network and organic compounds covalently bonded to the network via a spacer group, where the organic compounds are present in the interior of the particles and optionally also on the surface of the particles. The present invention furthermore relates to processes for the preparation of the particles and to the use thereof in formulations and compositions, in particular in compositions having light-protection properties.Type: ApplicationFiled: May 12, 2005Publication date: October 23, 2008Inventors: Thomas Walenzyk, Christophe Carola, Herwig Buchholz
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Publication number: 20080199414Abstract: The invention relates to cosmetic formulations, pharmaceutical preparations, food products and food supplements containing flavonoid derivatives. The flavonoid derivatives act therein, for instance, as UV filter. Some flavonoid derivatives represent novel compounds.Type: ApplicationFiled: April 22, 2008Publication date: August 21, 2008Inventors: Corinna Wirth, Herwig Buchholz, Christophe Carola
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Publication number: 20080182879Abstract: Novel compounds of the formula I in which R, X and n are as defined herein, are inhibitors of tyrosine kinase and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.Type: ApplicationFiled: April 1, 2008Publication date: July 31, 2008Inventors: Teresa MUJICA-FERNAUD, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
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Publication number: 20080112905Abstract: The invention relates to complexes of certain flavonoid derivatives, of the formula (1), where R1 and R2 are selected from H and OR11, where OR11 stands, independently of one another, for OH, straight-chain or branched C1- to C20-alkoxy groups, straight-chain or branched C3- to C20-alkenyloxy groups, straight-chain or branched C1- to C20-hydroxyalkoxy groups, where the hydroxyl group(s) may be bonded to a primary or secondary carbon atom in the chain and furthermore the alkyl chain may also be interrupted by oxygen, and/or C3- to C10-cycloalkoxy groups and/or C3- to C12-cycloalkenyloxy groups, where the rings may in each case also be bridged by —(CH2)n— groups, where n=1 to 3, and/or mono- and/or oligoglycosyl radicals, with the proviso that at least one radical from R1 and R2 stands for OR11, and R3 to R10 may be identical or different and stand, independently of one another, for radicals which are substantially inert with respect to the UV properties, to compositions which comprise such complexes, to corresType: ApplicationFiled: November 3, 2005Publication date: May 15, 2008Applicant: MERCK PATENT GMBHInventors: Christophe Carola, Anne Toullec, Herwig Buchholz
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Patent number: 7354945Abstract: Novel compounds of the formula I in which R, X and n are as defined herein, are inhibitors of tyrosine kinase and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.Type: GrantFiled: December 2, 2003Date of Patent: April 8, 2008Assignee: Merck Patent GmbHInventors: Teresa Mujica-Fernaud, Herwig Buchholz, Christophe Carola, Wilfried Rautenberg, Christian Sirrenberg
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Publication number: 20080045478Abstract: The invention relates to complexes of specific flavonoid derivatives, to preparations containing derivatives of this type, to corresponding methods for producing said derivatives or preparations containing the latter and to the use of the latter, in particular for the care, preservation or improvement of the general condition of the skin or hair.Type: ApplicationFiled: July 12, 2005Publication date: February 21, 2008Applicant: MERCK PATENT GMBHInventors: Herwig Buchholz, Ralf Rosskopf, Christophe Carola
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Publication number: 20080044364Abstract: The invention relates to compounds of the formula I where R1 to R10 may be identical or different and are selected from H, OR11, straight-chain or branched C1- to C20-alkyl groups or hydroxyalkyl groups, straight-chain or branched C3- to C20-alkenyl groups and/or C3- to C12-cycloalkenyl groups, where the rings may each also be bridged by —(CH2)n— groups, where n=1 to 3, where all OR11, independently of one another, stand for OH, C1- to C20-alkoxy groups, C3- to C20-alkenyloxy groups, straight-chain or branched C1- to C20-hydroxyalkoxy groups and/or C3- to C10-cycloalkoxy groups and/or C3- to C12-cycloalkenyloxy groups, where the rings may each also be bridged by —(CH2)n— groups, where n=1 to 3, and/or mono- and/or oligoglycosyl radicals, CD stands for a cyclodextrin molecule, o stands for the number 1 and p stands for a number from the range 0.5 to 50, with the proviso that at least 2 radicals from R1 to R7 stand for OH and that at least 1 pair of adjacent —OH groups is present in the molecule.Type: ApplicationFiled: November 4, 2005Publication date: February 21, 2008Inventors: Christophe Carola, Anne Toullec, Herwig Buchholz