Abstract: Provided are compounds of Formula (II): or a pharmaceutically acceptable salt thereof, wherein R1, n, and Y1 are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (II), or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula (II), or a pharmaceutically acceptable salt thereof.

Abstract: Various embodiments of the present technology generally relate to enhancements to spreadsheet tables. More specifically, embodiments of the present technology include systems and methods for incorporating various table column operations into table columns headers, thereby simplifying the act of propagating a desired effect across a range that exactly matches the table column. In an embodiment, a spreadsheet application detects a cell event in a spreadsheet, wherein the cell event affects one or more cells of the spreadsheet, determines that a cell of the one or more cells is inside a range that makes up a table in the spreadsheet, identifies a table column of the table to which the cell belongs, identifies metadata for the table column, wherein the metadata for the table column comprises column configuration instructions, and applies the column configuration instructions to the cell.

Abstract: Among other things, a rowing technology includes a first rowing machine having an electromagnetic brake providing a resistance to a rower of the machine in each rowing stroke of a series of rowing strokes of the rower An electronic controller causes the resistance of the electromagnetic brake to vary over each rowing stroke in a profile that emulates resistance to which another rower in a shell on water or on a second rowing machine is subjected in each rowing stroke of a corresponding series of rowing strokes.

Abstract: The present disclosure is directed to emulating physical-device input for an automated-testing framework. In particular, the methods and systems of the present disclosure may: determine a physical-device input associated with an automated-test script for an automated-testing framework comprising one or more proprietary test devices; emulate, via the automated-testing framework and at least one proprietary physical input device associated with the proprietary test device(s), the physical-device input; receive, from the proprietary test device(s) and via the automated-testing framework, data generated responsive to the emulated physical-device input; and compare the data generated responsive to the emulated physical-device input with expected data specified by the automated-test script for the automated-testing framework.

Abstract: An automated video game testing framework and method includes communicatively coupling an application programming interface (API) to an agent in a video game, where the video game includes a plurality of in-game objects that are native to the video game. The agent is managed as an in-game object of the video game. A test script is executed to control the agent, via the API, to induce gameplay and interrogate a behavior of a test object. The test object is identified from the plurality of in-game objects based on a query that specifies an object attribute of the test object.

Abstract: A method that includes winding a composite fabric around a mandrel to form a plurality of layers defining an annulus extending along a central longitudinal axis, where the composite fabric includes a plurality of elongate axial fibers extending substantially in an axial direction relative to the longitudinal axis and a plurality of elongate circumferential fibers extending substantially in a circumferential direction relative to the longitudinal axis; and introducing, into at least a portion of the plurality of layers, a plurality of radial fibers extending substantially in the radial direction relative to the longitudinal axis, where the plurality of radial fibers mechanically bind one or more adjacent layers of the plurality of layers.

Abstract: An electronic device includes a microphone array to capture audio input data, a speaker array to render audio output data for playback; one or more sensors to detect an orientation of the microphone array, acoustic echo cancellation logic, and an interface. The acoustic echo cancellation logic applies acoustic echo cancellation to the audio input data to form echo-cancelled audio input data based on the orientation of the microphone array. The interface transmits the echo-cancelled audio input data over a communications channel as part of an audiovisual communication system.

Abstract: A method for calibrating a quantum-computing operation comprises: (a) providing a trial control-parameter value to the quantum computer; (b) receiving from the quantum computer a result of a characterization experiment enacted according to the trial control-parameter value; (c) computing a decoder estimate of an objective function evaluated at the trial control-parameter value based on decoding the result of the characterization experiment; (d) consuming the trial control-parameter value and the decoder estimate in a machine trained to return a model estimate of the objective function evaluated at the trial control-parameter value; and (e) selecting a new trial control-parameter value based on the model estimate.

Abstract: Various systems for the containment or delivery of a product are provided. The systems allow for the storage of products at low temperatures and include a container closure inserted into a container (10). The container closure may have an elastomeric body (12) and include a material (14) having a negative coefficient of thermal expansion. In other systems, the material having a negative coefficient of thermal expansion may be inserted between the elastomeric container closure and a seal. Other systems may include an insert at least partially embedded within the elastomeric body of a container closure, an actuator having a distal end movably attached to the insert, and a resilient element between the distal end of the actuator and the insert, wherein the resilient material expands radially upon displacing the distal end of the actuator toward the insert.

Abstract: An electronic device includes sensors configured to detect an orientation of a display, driver logic, and a speaker array. The driver logic processes the audio data received by an interface to form audio output data, and forms driver signals representing the audio output data based on the orientation of the display detected by the one or more sensors. The speaker array receives the driver signals formed orientation of the display, and renders the audio output data for playback based on the driver signals.

Abstract: An electronic device includes a microphone array configured to capture audio data, one or more sensors configured to detect an orientation of the microphone array, and digital signal processing (DSP) logic, and an interface. The DSP logic processes, based on the orientation of the microphone array detected by the one or more sensors, the audio data captured by the microphone array to form audio input data. The interface configured to transmit the audio input data over a communications channel to be output by another electronic device.

Abstract: A syringe nest assembly includes a base having a first surface and an opposing second surface and a first plate movably coupled to the base. The base includes a plurality of nesting units extending upwardly away from the first surface of the base. Each nesting unit includes a hollow body having a first open end distal from the first surface of the base and an opposing second open end. The first plate has a first surface and an opposing second surface. The first plate includes a plurality of apertures extending from the first surface to the second surface of the first plate. Each aperture of the first plate is generally aligned with a respective nesting unit of the base.

Abstract: Embodiments improve application gateway architecture by pushing secure managed service boundaries. Managed services that were previously available directly in application gateway code are separated from application gateway code and exposed to service clients in a controlled, secured manner via a RESTful API layer dedicated to the management and interaction of deployed managed services. The separation can be realized in management agents. A management agent receives a service request from an application and makes an API call to the dedicated management API layer of the managing application gateway. The application may run within a managed container on a user device. Responsive to the API call, the application gateway sends a control or configuration message to the management agent over HTTP. The management agent controls or configures the managed service to function or behave as dictated by the application gateway.

Abstract: A sidewalk shed for placement proximal to a building includes: a plurality of canopy support arrangements including base members securable to grade; a beam support structure securably disposed to upper portions of the plurality of the canopy support arrangements; and a canopy structure securably disposed to the beam support structure. The plurality of canopy support arrangements includes dual canopy support arrangements and single support arrangements. The canopy structure includes a parapet wall and a decking.

Abstract: Described herein are systems and methods for providing personalized oral care. A system for oral care comprises an oral insert. The oral insert is sized and shaped according to a user's oral cavity, and has a plurality of fluid nozzles and an effluence conduit to channel fluid out of the user's oral cavity. Pressurized fluid provided through the nozzles are directed to, for example, the interproximal spaces between the user's teeth. In some variations, a system comprises an oral insert and an elastomeric substrate that is attached to the oral insert. In some variations, the elastomeric substrate comprises a textured surface vibrates and/or mechanically agitates and/or translates along the surface of the user's teeth. In some variations, a system for oral care comprises a microbiome collection chamber. Some variations comprise dental shim devices that are used for acquiring oral structure data and alignment between the upper and lower arches.

Abstract: Embodiments improve application gateway architecture by pushing secure managed service boundaries. Managed services that were previously available directly in application gateway code are separated from application gateway code and exposed to service clients in a controlled, secured manner via a RESTful API layer dedicated to the management and interaction of deployed managed services. The separation can be realized in management agents. A management agent receives a service request from an application and makes an API call to the dedicated management API layer of the managing application gateway. The application may run within a managed container on a user device. Responsive to the API call, the application gateway sends a control or configuration message to the management agent over HTTP. The management agent controls or configures the managed service to function or behave as dictated by the application gateway.

Abstract: An electronic device includes a microphone array configured to capture audio data, one or more sensors configured to detect an orientation of the microphone array, and digital signal processing (DSP) logic, and an interface. The DSP logic processes, based on the orientation of the microphone array detected by the one or more sensors, the audio data captured by the microphone array to form audio input data. The interface configured to transmit the audio input data over a communications channel to be output by another electronic device.

Abstract: An automated video game testing framework and method includes communicatively coupling an application programming interface (API) to an agent in a video game, where the video game includes a plurality of in-game objects that are native to the video game. The agent is managed as an in-game object of the video game. A test script is executed to control the agent, via the API, to induce gameplay and interrogate one or more target objects selected from the plurality of in-game objects native to the video game. Video game data indicating a behavior of the one or more target objects during the gameplay is received. Based on the received video game data, performance of the video game is evaluated.

Abstract: An expandable porous framework, the framework containing a dry cementitious powder fill that when exposed to an aqueous media, will expand against the constraint of the framework and set to form a solid, hard and coherent material, the formwork being porous to liquids but substantially impermeable to the powder fill.