Abstract: Disclosed are compounds of Formula 1, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating Type I hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with BTK.

Abstract: The subject matter disclosed herein provides methods for presenting glucose level data. Glucose data for a patient may be received. A current glucose level and a rate of change of the current glucose level may be determined based on the received glucose data. A first interface may be displayed on a screen of a device. The first interface may include a unitary icon. The unitary icon may display the current glucose level and a visualization of the rate of change. Related apparatus, systems, techniques, and articles are also described.

Abstract: A continuous glucose monitor for wirelessly transmitting data relating to glucose value to a plurality of displays is disclosed, as well as systems and methods for limiting the number of display devices that can connect to a continuous glucose transmitter. In addition, security, including hashing techniques and a changing application key, can be used to provide secure communications between the continuous glucose transmitter and the displays. Also provided is a continuous glucose monitor and techniques for authenticating multiple displays, providing secure data transmissions to multiple displays, and coordinating the interaction of commands and data updates between multiple displays.

Abstract: Systems and methods for a continuous monitoring of analyte values received from an analyte sensor system are provided. One method for a wireless data communication between an analyte sensor system and a mobile device involves storing identification information associated with a transceiver of the analyte sensor system, the identification information entered by a user of the mobile device via a custom application running on the mobile device; causing the custom application to enter a background mode; searching for advertisement signals; receiving an advertisement signal from the transceiver; authenticating the transceiver based on the identification information; prompting the user to bring the custom application to a foreground mode; causing the custom application to request a confirmation from the user that a data connection with the transceiver is desired; receiving the confirmation from the user; and completing the data connection with the transceiver.

Abstract: The present disclosure provides polymeric systems that are able to undergo fast hydration and are useful for maintaining particle dispersions for extended periods of time.

Abstract: Implementations provide an in-person communication experience by generating a changable virtual viewpoint for a participant in an online communication. For instance, techniques described herein capture visual data about participants in an online communication, and create a realistic geometric proxy from the visual data. A virtual scene geometry is generated that mimics an arrangement of an in-person meeting for the online communication. According to various implementations, a virtual viewpoint displays a changing virtual viewpoint, such as based on a change in position of a participants face.

Abstract: In some aspects, the invention relates to a inflation independent sports ball comprising a foam core 15 and an outer covering 10, wherein the sports ball is selected from the group consisting of a football, a basketball, a volleyball and a soccer ball, wherein the sports ball 5 is devoid of an inflatable air bladder. In other aspects, the invention relates to a sports ball having a diameter and comprising a synthetic leather outer covering 10 at least partially covering a polyurethane foam core 15, wherein the foam core further comprises at least one internal compartment and a cylindrical body spanning at least part of the length of the diameter of the sports ball. In other aspects, the invention relates to a sports ball having an outer covering and a foam core, wherein the foam core 15 is not filled with foam entirely throughout its internal volume, but rather includes space for air.

Abstract: The subject matter disclosed herein provides methods for presenting glucose level data. Glucose data for a patient may be received. A current glucose level and a rate of change of the current glucose level may be determined based on the received glucose data. A first interface may be displayed on a screen of a device. The first interface may include a unitary icon. The unitary icon may display the current glucose level and a visualization of the rate of change. Related apparatus, systems, techniques, and articles are also described.

Abstract: Disclosed are compounds of Formula 1, or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, and R4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating Type I hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with BTK.

Abstract: Various approaches to touch sensing systems are disclosed As an example, a touch sensing system is disclosed that includes: an optical beam source to provide an optical beam; a pair of controllable beam deflectors comprising at least first and second beam deflectors, wherein the first beam deflector is configured to deflect the optical beam through a first angle towards a touch sensing region, and wherein the second beam deflector is configured to deflect scattered light from an object in the touch sensing region through a second angle; a detector, in particular a detector array; and an imaging system to image the deflected scattered light from the second beam deflector onto the detector array. The first and second beam deflectors are controlled in tandem to scan the touch sensing region.

Abstract: Embodiments of the present disclosure include methods and compositions for functionalizing molecules, such as oligonucleotides, with functional groups, including polyhistidine tags useful in affinity methods. Some embodiments include methods for modifying and purifying complex mixtures of molecules by exchange of functional tags.

Abstract: A junction box assembly may include a junction box base and a junction box cover. The junction box base may define a junction box internal recess. The junction box cover may include a mounting flange, a cover barrier spaced from the mounting flange, and a wall extending between the mounting flange and the cover barrier and defining a junction box cover recess. The junction box cover may be configured to be alternatively coupled to a backing panel to form a junction box, such that either (1) the cover barrier of the junction box cover is received in the junction box internal recess and defines a first junction box space, or (2) the cover barrier is spaced from the backing panel and on a side of the backing panel opposite the junction box base and defines a second junction box space larger than the first junction box space.

Abstract: The subject matter disclosed herein provides methods for presenting glucose level data. Glucose data for a patient may be received. A current glucose level and a rate of change of the current glucose level may be determined based on the received glucose data. A first interface may be displayed on a screen of a device. The first interface may include a unitary icon. The unitary icon may display the current glucose level and a visualization of the rate of change. Related apparatus, systems, techniques, and articles are also described.

Abstract: There is disclosed in one example a data exchange layer (DXL) broker, including: a network interface to communicatively couple to a data exchange layer (DXL), the DXL including an enterprise service bus (ESB) configured to provide one-to-one device communications over a publish-subscribe fabric; hardware including at least a processor; and instructions encoded on one or more computer-readable mediums to instruct the processor to provide DXL broker software configured to: receive a DXL request message via the DXL, the request message directed to a DXL service; determine that the DXL service is available; and forward the request message to a DXL endpoint via the DXL.

Abstract: A continuous glucose monitor for wirelessly transmitting data relating to glucose value to a plurality of displays is disclosed, as well as systems and methods for limiting the number of display devices that can connect to a continuous glucose transmitter. In addition, security, including hashing techniques and a changing application key, can be used to provide secure communications between the continuous glucose transmitter and the displays. Also provided is a continuous glucose monitor and techniques for authenticating multiple displays, providing secure data transmissions to multiple displays, and coordinating the interaction of commands and data updates between multiple displays.

Abstract: Systems and methods for a continuous monitoring of analyte values received from an analyte sensor system are provided. One method for a wireless data communication between an analyte sensor system and a mobile device involves storing identification information associated with a transceiver of the analyte sensor system, the identification information entered by a user of the mobile device via a custom application running on the mobile device; causing the custom application to enter a background mode; searching for advertisement signals; receiving an advertisement signal from the transceiver; authenticating the transceiver based on the identification information; prompting the user to bring the custom application to a foreground mode; causing the custom application to request a confirmation from the user that a data connection with the transceiver is desired; receiving the confirmation from the user; and completing the data connection with the transceiver.

Abstract: Disclosed is an in-the-bowl dispensing device designed to dispense two liquid compositions into a toilet bowl at two separate time intervals. One dispensing action takes place during the flush of the toilet bowl and a second separate dispensing action takes place after the flush of the toilet bowl is complete. In this manner the second liquid composition is retained in the toilet bowl until the toilet bowl is flushed by the next user.

Abstract: A screen assembly including a flexible screen having a first edge and a second edge, a substantially vertical supporting member about which the screen can be wound/unwound and to which the first edge of the screen is mounted, a drum associated with at least one end of the supporting member, at least one line member that can be wound onto and off the drum, and a first removable clip. The first removable clip including: a body portion defining an opening for receiving a portion of a supporting member and drum assembly, and an upwardly extending portion, wherein the upwardly extending portion is configured to hold the at least one line member relative to an external surface of the drum during transportation of the screen assembly or prior to operation of the screen assembly.