Abstract: An adjustable spinal stabilization system for maintaining preselected spacing and movement between adjacent vertebrae in a spinal column and for providing overall stability thereto. The system includes at least one interlaminar member positioned in the spaces intermediate a first vertebra and the vertebrae positioned immediately above or immediately below and adjacent to the first vertebra. The interlaminar member is operatively connected to an adjustable support structure and cooperates therewith to maintain the preselected spacing between adjacent vertebrae and to provide overall stability to the spinal column.

Abstract: The disclosed technology includes a medical probe including an expandable basket assembly. The basket assembly includes a spine, and the spine includes a deformed region, a spine protrusion, that can be used to deposit an electrode. The electrode can be formed of an electrode assembly that can include an insulative layer and an electrode layer. The electrode assembly is deposed on the spine protrusion so as to avoid the need of separate electrode components that must be positioned along the length of the spine.

Abstract: In one embodiment, a probe apparatus includes a shaft having a distal end, a tube containing separate powder granules of a ferrite, the tube being fixed to the distal end of the shaft, a coil disposed around the tube, and electrical wires connected to the coil so as to read out a signal generated across the coil due to an externally-applied magnetic field.

Abstract: A portable cooler container with active temperature control, comprising: a container body having a chamber configured to receive and hold one or more containers of medicine; a lid operable to access the chamber; and a temperature control system comprising one or more thermoelectric elements configured to actively heat or cool at least a portion of the chamber, circuitry configured to control an operation of the one or more thermoelectric elements to heat or cool at least a portion of the chamber to a predetermined temperature or temperature range; and a display screen disposed on one of the container body and the lid, the display screen configured to selectively display one or more of information associated with the operation of the portable cooler, information associated with the containers of medicine in the portable cooler, information associated with scheduled taking of the containers of medicine, and advertisements.

Abstract: Apparatus, having an insertion tube that is configured to be inserted into a body cavity. The apparatus also includes a distal tip connected to the insertion tube, the distal tip having an external surface and a cavity formed in the external surface, the cavity being surrounded by a region of the external surface having a curvature. The apparatus further includes a microelectrode configured to fit into the cavity so that a surface of the microelectrode is contoured, located and oriented to conform with the curvature of the region.

Abstract: Embodiments of the present invention include a medical probe having an insertion tube, a basket assembly, an axial electrode, and a plurality of radial electrodes. The insertion tube is configured for insertion into a body cavity of a patient. The basket assembly has a proximal end that is connected distally to the insertion tube and includes a plurality of resilient spines, which are configured to bow radially outward from an axis of the basket assembly and are conjoined at a distal end of the basket assembly. The axial electrode is disposed at the distal end of the basket assembly, having a diameter of at least 1.5 millimeters, and is configured to contact tissue in the body cavity. The plurality of radial electrodes are configured to contact the tissue in the body cavity and include radial electrodes disposed on the spines.

Abstract: A vehicle port door includes a housing and an interlocking linkage assembly. The interlocking linkage assembly is pivotably connected to the housing.

Abstract: The disclosed technology includes a spine member for an end effector, the spine member extending along a longitudinal axis from a proximal end to a distal end. The spine member includes a unidirectional proximal stop member to allow an electrode to slide in a direction distally but not proximally and a distal stop member to prevent an electrode from sliding past.

Abstract: A system for performing a minimally invasive interventional fusion procedure on a sacroiliac joint of a patient. The system may include a disposable sterile packed implant and kit including access, bone cutting, accessory and extraction instruments.

Abstract: A medical probe includes a shaft and an expandable flexible distal-end assembly. The shaft is configured for insertion into a cavity of organ of a patient. The expandable flexible distal-end assembly, which is fitted at a distal-end of the shaft, includes a flat flexible backing sheet, including irrigation channels, and two flexible substrates having respective arrays of electrodes disposed thereon, the substrates attached one on either side of the backing sheet.

Abstract: A medical instrument includes a shaft, multiple flexible spines and multiple electrodes. The shaft is configured for insertion into a body of a patient. The multiple flexible spines have respective first ends that are connected to a distal end of the shaft and respective second ends that are free-standing and unanchored. The spines are bent proximally such that the second ends are more proximal than the first ends. Each of the flexible spines includes a tensile layer configured to cause the flexible spine to bend proximally. The multiple electrodes are disposed over the flexible spines.

Abstract: A method and system for monitoring a user's intoxication including receiving a set of signals, derived from a set of samples collected from the user at a set of time points; providing a sobriety task to the user proximal to a time point of the set of time points; generating a performance dataset characterizing performance of the sobriety task by the user; receiving a supplementary dataset characterizing a demographic profile of the user and/or a physiological state of the user; determining a set of values of an intoxication metric, derived from the set of signals; generating a predicted temporal profile of the intoxication metric for the user based upon the set of values, the set of time points, and the supplementary dataset; generating an analysis of the user's sobriety based upon the performance dataset and the predicted temporal profile; and providing a notification to the user based upon the analysis.

Abstract: In one embodiment, a catheter manufacturing method includes forming flexible circuit strips with respective different symbols marked thereon, each strip including at least one respective electrode, attaching one end of each of the flexible circuit strips to a catheter coupler with the flexible circuit strips being ordered around a circumference of the catheter coupler responsively to the respective symbols of respective ones of the flexible circuit strips, and forming a distal end assembly of a catheter, the distal end assembly comprising the flexible circuit strips attached to the catheter coupler.

Abstract: In some embodiments, a wearable device detects a trigger event. The trigger event indicates a type of measurement to take. Based on the trigger event, the wearable device selects an instruction audio message corresponding to the type of measurement to be taken. The instruction audio message includes instructions for how to conduct the type of measurement. The wearable device connects to an appropriate measuring apparatus based on the type of measurement to be taken and the instruction audio message. The wearable device plays the instruction audio message to a patient of the wearable device. The wearable device receives measurements from the appropriate measuring apparatus.

Abstract: A helmet is provided that can include a cage defining a front end, a back end opposite the front end, a first lateral end and a second lateral end opposite the first lateral end. The cage can include multiple longitudinal beams that extend between the back end of the cage and the front end of the cage; and a transverse beam that extends between the first lateral end of the cage and the second lateral end of the cage. The transverse beam can be anchored to the multiple longitudinal beams. The helmet can include a body that fully encapsulates the multiple longitudinal beams of the cage and that partially encapsulates the transverse beam. The body can define multiple vents. Each vent can be situated between two adjacent longitudinal beams. The transverse beam can extend through one of the multiple vents.

Abstract: In one embodiment, a catheter apparatus is configured to be inserted into a body part of a living subject, and including an elongated deflectable element including a distal end, an expandable basket assembly disposed at the distal end and comprising a plurality of splines and a plurality of electrodes disposed on the splines, an irrigation channel disposed in the elongated deflectable element, and an inflatable balloon disposed in the expandable basket assembly and including a plurality of irrigation holes in fluid connection with the irrigation channel.

Abstract: An isolated or purified AON for modifying pre-mRNA splicing in the Receptor for Advanced Glycation End-products (RAGE) to modulate splicing of the RAGE gene transcript or part thereof is provided.

Abstract: A portable cooler container is provided. The temperature control system cools a chamber of the container to transport temperature sensitive contents via the container. An electronic display screen on one of the lid and the container body selectively displays an electronic shipping label for the portable cooler container.

Abstract: A strengthened cover glass or glass-ceramic sheet or article as well as processes and systems for making the strengthened glass or glass-ceramic sheet or article is provided for use in consumer electronic devices. The process comprises cooling the cover glass sheet by non-contact thermal conduction for sufficiently long to fix a surface compression and central tension of the sheet. The process results in thermally strengthened cover glass sheets for use in or on consumer electronic products.

Abstract: A container with active temperature control system is provided. The active temperature control system is operated to heat or cool a chamber sized to receive a beverage therein. The container includes an insulated vessel that has the chamber and a cooling or heating unit. The cooling or heating unit includes a thermoelectric element in thermal communication with the chamber, phase change material in thermal communication with the thermoelectric element, a power storage device, and circuitry to control the operation of the thermoelectric element. The cooling or heating unit is operable to increase or decrease or maintain a temperature of the beverage in the chamber by operating the thermoelectric element to draw heat from the chamber and transfer it to the module of phase change material.