Patents by Inventor Christopher A. Voigt

Christopher A. Voigt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12209245
    Abstract: Methods for making synthetic gene clusters are described.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: January 28, 2025
    Assignee: The Regents of the University of California
    Inventors: Ethan Mirsky, Karsten Temme, Christopher A. Voigt, Dehua Zhao
  • Patent number: 12209965
    Abstract: A method and apparatus are provided for detecting respective potential presences of respective different cellular fluorescence pattern types on a biological cellular substrate including human epithelioma cells (HEp cells), wherein the fluorescence pattern types include different antinuclear antibody fluorescence pattern types. A method is also provided for detecting potential presences of different cellular fluorescence pattern types on a biological cellular substrate including human epithelioma cells by means of digital image processing, as well as a computing unit, a data network device, a computer program product and a data carrier signal therefor.
    Type: Grant
    Filed: January 19, 2022
    Date of Patent: January 28, 2025
    Assignee: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Christopher Krause, Jens Krauth, Stefan Gerlach, Christian Marzahl, Melanie Hahn, Joern Voigt
  • Publication number: 20250027228
    Abstract: The invention relates to methods and products for generating diverse libraries of genetic material. The products include libraries and constructed nucleic acids as well as kits and databases and systems thereof.
    Type: Application
    Filed: February 7, 2024
    Publication date: January 23, 2025
    Applicant: Massachusetts Institute of Technology
    Inventors: Dehua Zhao, Christopher A. Voigt, Michael Joseph Smanski
  • Publication number: 20240321267
    Abstract: A system and method are described for dialogue management by determining a transition from a domain or a use case to another and initiating a switch suggestion in a human-computer conversation for rendering services to a user based on the updated domain or use case for a dialogue. The method comprises determining a first use-case in the human-computer conversation and assigning a first use-case score to the said first use-case. The method then comprises determining a second use-case in the human-computer conversation and assigning a second use-case score to the said second use-case. Further, the method comprises determining whether to make the use-case switch suggestion to the said second use-case based on the said first use-case score and the said second use-case score. The invention aligns the system to extract intended information from/for the user thereby making the system more efficient, approachable and user-friendly by saving time and cost.
    Type: Application
    Filed: June 23, 2022
    Publication date: September 26, 2024
    Inventors: Christopher VOIGT, Alam Aseequl KHAN, Kai Samuel David Erik KARREN, Michael SCHMITS, Mohammad Fayadan HOSSAIN
  • Patent number: 11976270
    Abstract: Provided herein, in some aspects, are methods and compositions for producing single-stranded DNA (ssDNA) having uniform length.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: May 7, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Angela Belcher, Christopher A. Voigt, Uyanga Tsedev, Tae-Gon Cha
  • Patent number: 11946162
    Abstract: The invention relates to methods and products for generating diverse libraries of genetic material. The products include libraries and constructed nucleic acids as well as kits and databases and systems thereof.
    Type: Grant
    Filed: March 17, 2021
    Date of Patent: April 2, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Dehua Zhao, Christopher A. Voigt, Michael Joseph Smanski
  • Patent number: 11898141
    Abstract: Disclosed is a method of generating a set of sequence-verified nucleic acid elements for the combinatorial construction of genetic elements. The method includes: providing a plurality of nucleic acid parts; assembling nucleic acid parts to form a one or more nucleic acid elements, wherein the nucleic acid elements include at least two sequences selected from the plurality of parts; and determining the sequence of the nucleic acid elements. Further disclosed is a pool of higher-order nucleic acid constructs or amplification products thereof, comprising one or more nucleic acid elements as well as kits including a pool of sequence-verified nucleic acid elements of claims and/or a pool of higher-order nucleic acid constructs; and a plurality of primers for retrieving one or more sequence-verified nucleic acid elements and/or higher-order nucleic acid constructs.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: February 13, 2024
    Assignees: The Broad Institute, Inc., Massachusetts Institute of Technology
    Inventors: Robert Nicol, Lauren Andrews, Tarjei Mikkelsen, Christopher Voigt
  • Publication number: 20230227508
    Abstract: Disclosed herein, in some embodiments, non-naturally occurring proteins (e.g., non-naturally occurring modified proteins) that may be useful in the treatment of bacterial and viral infections, including SARS-CoV-2 infection, host cells comprising the same, and methods of treating bacterial and viral infections including SARS-CoV-2 infection. Also provided herein are host cells comprising fusion proteins for split intein-based selection of peptides that bind a target protein, methods of using the same, and methods of identifying peptides that bind a target protein.
    Type: Application
    Filed: June 11, 2021
    Publication date: July 20, 2023
    Applicant: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Andrew King, Emerson Glassey
  • Publication number: 20230183677
    Abstract: Disclosed herein are biosensors that are hyperspectral reporters. The biosensors are useful for detecting information about the environment and environmental conditions in a number of fields including agriculture. Also provided are methods of making and using the biosensors.
    Type: Application
    Filed: October 7, 2022
    Publication date: June 15, 2023
    Applicant: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Yonatan Chemla, Itai Levin
  • Publication number: 20230141310
    Abstract: Disclosed herein, in some embodiments, are vectors encoding biosynthetic enzymes from gut microbiome-derived bacterium (e.g., Clostridia enzymes), engineered cells comprising the vectors, and methods of using biosynthetic enzymes from gut microbiome-derived bacterium (e.g., Clostridia enzymes) to produce fatty acid amides.
    Type: Application
    Filed: July 12, 2022
    Publication date: May 11, 2023
    Applicant: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Fang-Yuan Chang
  • Patent number: 11591604
    Abstract: Provided herein, in some aspects, are tools (e.g., methods, compositions and nucleic acids) for building genetic circuits in Bacteroides and Parabacteroides bacteria, as well as the bacteria containing the genetic circuits.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: February 28, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy Kuan-Ta Lu, Mark K. Mimee, Christopher Voigt, Alex C. Tucker
  • Publication number: 20220411344
    Abstract: The invention relates to methods for promoting fixed nitrogen from atmospheric nitrogen, and related products. Endophytic bacteria having an exogenous nif cluster promote fixed nitrogen for cereal plants.
    Type: Application
    Filed: August 26, 2022
    Publication date: December 29, 2022
    Applicant: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Min-Hyung Ryu, Mi Ryoung Song
  • Patent number: 11479516
    Abstract: The invention relates to methods for promoting fixed nitrogen from atmospheric nitrogen, and related products. Endophytic bacteria having an exogenous nif cluster promote fixed nitrogen for cereal plants.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: October 25, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Min-Hyung Ryu, Mi Ryoung Song
  • Patent number: 11441162
    Abstract: Disclosed herein, in some embodiments, are vectors encoding biosynthetic enzymes from gut microbiome-derived bacterium (e.g., Clostridia enzymes), engineered cells comprising the vectors, and methods of using biosynthetic enzymes from gut microbiome-derived bacterium (e.g., Clostridia enzymes) to produce fatty acid amides.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: September 13, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Fang-Yuan Chang
  • Publication number: 20220162544
    Abstract: Disclosed herein are engineered rhizobia having nif clusters that enable the fixation of nitrogen under free-living conditions, as well as ammonium and oxygen tolerant nitrogen fixation under free-living conditions. Also provided are methods for producing nitrogen for consumption by a cereal crop using these engineered rhizobia.
    Type: Application
    Filed: March 19, 2020
    Publication date: May 26, 2022
    Applicant: Massachusetts Institute of Technology
    Inventors: Christopher A. Voigt, Min-Hyung Ryu
  • Patent number: 11208664
    Abstract: The present disclosure relates, in some aspects, to bile acid sensors.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: December 28, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Christopher Voigt, Mao Taketani
  • Patent number: 11124498
    Abstract: Disclosed herein, inter alia, are compositions for modulating protease activity and treating cancer.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: September 21, 2021
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Michael A. Fischbach, Chun-Jun Guo, Christopher A. Voigt, Fang-Yuan Chang, Jon Clardy, Thomas Wyche
  • Publication number: 20210284995
    Abstract: The invention relates to methods and products for generating diverse libraries of genetic material. The products include libraries and constructed nucleic acids as well as kits and databases and systems thereof.
    Type: Application
    Filed: March 17, 2021
    Publication date: September 16, 2021
    Applicant: Massachusetts Institute of Technology
    Inventors: Dehua Zhao, Christopher A. Voigt, Michael Joseph Smanski
  • Publication number: 20210163969
    Abstract: Disclosed are compositions, methods, and kits for performing cell-free protein synthesis (CFPS). The disclosed compositions, methods, and kits include or utilize components prepared from plant plastids or extracts thereof. The compositions, methods, and kits may be used for in vitro protein synthesis and prototyping of genetic expression in plants and are suitable for automation.
    Type: Application
    Filed: February 8, 2021
    Publication date: June 3, 2021
    Inventors: Michael Christopher Jewett, Lauren Clark, Christopher A. Voigt, Eszter Majer
  • Patent number: 10968446
    Abstract: The invention relates to methods and products for generating diverse libraries of genetic material. The products include libraries and constructed nucleic acids as well as kits and databases and systems thereof.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: April 6, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Dehua Zhao, Christopher Voigt, Michael Joseph Smanski