Abstract: The sale of a vehicle may involve many cost and profit components. It is generally impossible for a potential buyer to know all of these components. For example, dealers may be paid by original equipment manufacturers (OEMs) on their Customer Satisfaction Index (CSI) and volume bonus. Embodiments disclosed herein may determine and present to a user an accurate estimate of dealer cost, taking into consideration an aggregate of dealer cost components. For each component, a predictive model may be built to determine an expected value at a particular level. An average of the expected value of the component is then calculated for the most recent month. From that, an average bonus payout per vehicle for the most recent month may be determined. A base dealer cost is adjusted to account for these payouts to produce an accurate estimate of actual dealer cost.

Abstract: The present invention relates to novel muteins of human fibroblast growth factor 21 with reduced deamidation compared to wild-type human FGF-21. Both protein and the respective encoding nucleic acid species are disclosed. The invention also embodies vectors and host cells for the propagation of said nucleic acid sequences and the production of said muteins. Also disclosed are methods for treating type 2 diabetes, obesity, or metabolic syndrome.

Abstract: Several implementations of a fan folding mechanism for folding flaps of a case into a fan fold arrangement are disclosed and described. In one implementation, the fan folding mechanism comprises four shoes, arranged to allow one shoe to contact a flap on each of four sides of the case. A finger, carried by each of the four shoes is configured for movement between a retracted position and an extended position, such that in the retracted position, each finger is in contact with a leading corner of a different flap of the case and the flaps are in an open position and in the extended position, each finger is in contact with the same leading corner of the same flap, and the flap is in the closed position. Four suction cups, each configured for releasable attachment to a trailing corner of a flap, may inhibit contention between flaps.

Abstract: The present invention relates to novel muteins of human fibroblast growth factor-21 with reduced susceptibility for proteolytic degradation when expressed in yeast. Both protein and the respective encoding nucleic acid species are disclosed. The invention also embodies vectors and host cells for the propagation of said nucleic acid sequences and the production of said muteins. Also disclosed are methods for treating type 2 diabetes, obesity, or metabolic syndrome.

Abstract: Several implementations of a fan folding mechanism for folding flaps of a case into a fan fold arrangement are disclosed and described. In one implementation, the fan folding mechanism comprises four shoes, arranged to allow one shoe to contact a flap on each of four sides of the case. A finger, carried by each of the four shoes is configured for movement between a retracted position and an extended position, such that in the retracted position, each finger is in contact with a leading corner of a different flap of the case and the flaps are in an open position and in the extended position, each finger is in contact with the same leading corner of the same flap, and the flap is in the closed position. Four suction cups, each configured for releasable attachment to a trailing corner of a flap, may inhibit contention between flaps.

Abstract: The present invention relates to novel muteins of human fibroblast growth factor 21 with reduced capacity of O-glycosylation when expressed in yeast compared to wild-type human FGF-21. Both protein and the respective encoding nucleic acid species are disclosed. The invention also embodies vectors and host cells for the propagation of said nucleic acid sequences and the production of said muteins. Also disclosed are methods for treating type 2 diabetes, obesity, or metabolic syndrome.

Abstract: A dishwasher with both a single use dispenser and a bulk dispenser, where wash aid can be selectively dispensed into a wash chamber of the dishwasher directly from the single use dispenser or indirectly from the bulk dispenser through the single use dispenser.

Abstract: A personal wearable communication and speaker entertainment system which provides improved quality audio response and which does not interfere with the wearer's activities or block environmental sounds is disclosed. The speaker system is connected to or in communication with a conventional source of audio signals, such as radio, tape player, CD player, cellular telephone or the like.