Abstract: A laser probe includes a cannula, at least one optical fiber positioned within the cannula, and a lens positioned within the cannula at a distal end of the fiber. The lens is adapted to receive a laser beam from the optical fiber at a proximal end of the lens and to transmit the laser beam towards a distal end of the lens. The laser probe includes an optical element configured coupled to the cannula by a brazed joint and to receive the laser beam from the distal end of the lens and emit the laser beam from the probe. The brazed joint may form a hermetic or liquid-tight seal between the optical element and the cannula.

Abstract: A catheter system (100) for placement within a treatment site (106) at a vessel wall (208A) or a heart valve includes an energy source (124), a balloon (104), an energy guide (122A), and a tissue identification system (142). The energy source (124) generates energy. The balloon (104) is positionable substantially adjacent to the treatment site (106). The balloon (104) has a balloon wall (130) that defines a balloon interior (146). The balloon (104) is configured to retain a balloon fluid (132) within the balloon interior (146). The energy guide (122A) is configured to receive energy from the energy source (124) and guide the energy into the balloon interior (146) so that plasma is formed in the balloon fluid (132) within the balloon interior (146). The tissue identification system (142) is configured to spectroscopically analyze tissue within the treatment site (106).

Abstract: A catheter system for treating a vascular lesion within or adjacent to a vessel wall within a body of a patient includes a single light source that generates light energy, a first light guide and a second light guide, and a multiplexer. The first light guide and the second light guide are each configured to selectively receive light energy from the light source. The multiplexer receives the light energy from the light source in the form of a source beam and selectively directs the light energy from the light source in the form of individual guide beams to each of the first light guide and the second light guide. The multiplexer includes a system of optical valves arranged in a linear sequence within the multiplexer. The system of optical valves includes an individual valve that receives the light energy from the light source.

Abstract: A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108) or heart valve includes a first light source (124), a plurality of light guides (122A), a multiplexer (128) and a multiplexer alignment system (142). The first light source (124) generates light energy. The plurality of light guides (122A) are each configured to alternatingly receive light energy from the first light source (124). Each light guide (122A) has a guide proximal end (122P). The multiplexer (128) receives the light energy from the first light source (124). The multiplexer (128) alternatingly directs the light energy from the first light source (124) to each of the plurality of light guides (122A). The multiplexer alignment system (142) is operatively coupled to the multiplexer (128). The multiplexer alignment system (142) includes a second light source (270) that generates a probe source beam (270A) that scans the guide proximal end (122P) of each of the plurality of light guides (122A).

Abstract: The present disclosure relates to a multi-core optical fiber cable (MCF). In some embodiments, an MCF comprises a plurality of cores, a cladding surrounding the plurality of cores, wherein a refractive index of one or more of the plurality of cores is greater than a refractive index of the cladding, and a coating surrounding the cladding, a distal end free of the coating and having a reduced diameter. The MCF also comprise an annular gap formed between the distal end of the MCF and the inner surface of the cannula, wherein the concentricity of the distal end of the MCF with the inner passage of the cannula is maintained.

Abstract: A catheter system for treating a vascular lesion within or adjacent to a vessel wall within a body of a patient includes a single light source that generates light energy, a first light guide and a second light guide, and a multiplexer. The first light guide and the second light guide are each configured to selectively receive light energy from the light source. The multiplexer receives the light energy from the light source in the form of a source beam and selectively directs the light energy from the light source in the form of individual guide beams to each of the first light guide and the second light guide.

Abstract: An optical fiber cable having reduced or minimal colorant may include a plurality of optical fiber components and a jacket formed around the plurality of optical fiber components. Each optical fiber component may include at least one optical fiber and a buffer layer surrounding the at least one optical fiber. The respective buffer layers may be free of colorant, and physical indicia may be selectively formed as surface variations on a suitable number of buffer layers to facilitate identification of the plurality of optical fiber components. The jacket may include one or more polymeric materials that are not blended or compounded with any colorant.

Abstract: A catheter system for treating a treatment site within or adjacent to a vessel wall includes a light source, a balloon, a light guide, and an optical analyzer assembly. The light source generates light energy. The balloon is positionable substantially adjacent to the vascular lesion. The balloon has a balloon wall that defines a balloon interior that receives a balloon fluid. The light guide receives light energy from the light source at a guide proximal end and guides the light energy toward a guide distal end and into the balloon interior. The optical analyzer assembly is configured to optically analyze light energy emitted from the guide proximal end of the light guide.

Abstract: A method for treating a treatment site within or adjacent to a vessel wall or a heart valve, includes the steps of (i) generating light energy with a light source; (ii) positioning a balloon substantially adjacent to the treatment site, the balloon having a balloon wall that defines a balloon interior that receives a balloon fluid; (iii) receiving the light energy from the light source with a light guide at a guide proximal end; (iv) guiding the light energy with the light guide in a first direction from the guide proximal end toward a guide distal end that is positioned within the balloon interior; and (v) optically analyzing with an optical analyzer assembly light energy from the light guide, wherein the light energy that is analyzed moves in a second direction that is opposite the first direction.

Abstract: A catheter system for treating a treatment site within or adjacent to a vessel wall or a heart valve within a body of a patient includes an energy source, an inflatable balloon, an energy guide, and an acoustic sensor. The energy source generates energy. The inflatable balloon is positionable substantially adjacent to the treatment site. The inflatable balloon has a balloon wall that defines a balloon interior that receives a balloon fluid. The energy guide receives energy from the energy source and guides the energy into the balloon interior. The acoustic sensor is positioned outside the body of the patient. The acoustic sensor senses acoustic sound waves generated in the balloon fluid within the balloon interior. The acoustic sensor generates a sensor signal based at least in part on the sensed acoustic sound waves. A system controller receives the sensor signal from the acoustic sensor and controls operation of the catheter system based at least in part on the sensor signal.

Abstract: A catheter system includes a power source, a controller, and a light guide. The power source generates a plurality of energy pulses. The controller controls the power source so that the plurality of energy pulses cooperate to produce a composite energy pulse having a composite pulse shape. The light guide receives the composite energy pulse. The light guide emits light energy in a direction away from the light guide to generate a plasma pulse away from the light guide. The power source can be a laser and the light guide can be an optical fiber. Each of the energy pulses has a pulse width, and the energy pulses are added to one another so that the composite energy pulse has a pulse width that is longer than the pulse width of any one of the energy pulses. At least two of the energy pulses can have the same wavelength as or a different wavelength from one another.

Abstract: We provide an imaging system for use in a fluoroscopy procedure carried out on a subject, the imaging system being configured to receive images of a portion of the subject from an image acquisition device, the imaging system comprising an interface module for displaying images received from the image acquisition device to a user, and an optimisation module for determining, based on an image received from the image acquisition device, one or more properties of the image, wherein the optimisation module is configured to output a control routine.

Abstract: A catheter system for treating a vascular lesion within or adjacent to the vessel wall or heart valve includes a balloon and a fluid circulator. The balloon includes a balloon wall that defines a balloon interior. The balloon is configured to retain a catheter fluid within the balloon interior. The fluid circulator is coupled in fluid communication to the balloon interior. The fluid circulator is configured to selectively circulate the catheter fluid out of and back into the balloon interior during use of the catheter system. The fluid circulator is configured so that a temperature of the catheter fluid within the balloon interior is maintained within a predetermined temperature range. Additionally, the fluid circulator can be configured so that a pressure of the catheter fluid within the balloon interior is maintained within a predetermined pressure range. Further, a filtration system can be coupled in fluid communication with the fluid circulator to remove microparticles from the catheter fluid.

Abstract: A multifunctional medical device, apparatus or system that is capable of perforating a surgical procedure or operation and also capable of attracting, collecting, removing or reducing debris generated by the surgical procedure or operation, on a subject. The apparatus comprising a plurality of electrodes, two of which are configured to be in electrical communication with or being electrically connectable to opposite poles of a source of high voltage dc electricity to ionize, attract, collect, and remove or reduce debris. At least one of the electrodes is also configured to be part of a RF circuit to perform a surgical procedure or operation such as tissue cutting, cauterization tissue sealing or coagulating at a surgical site on the subject.

Abstract: Disclosed is a multifunctional medical device, apparatus or system that is capable of performing a surgical procedure or operation and also capable of removing or reducing smoke particles generated by the surgical procedure or operation on a subject, the apparatus comprising a plurality of electrodes, two of which are configured to be in electrical communication with or being electrically connectable to opposite poles of a source of high voltage dc electricity to ionize, and remove or reduce smoke particles, and at least one of which is also configured to be part of a RF circuit to perform a surgical procedure or operation such as tissue cutting, cauterization, tissue sealing or coagulating at a surgical site on the subject. Also disclosed is a method of employing the above disclosed device, apparatus or system or variations thereof to perform a surgical procedure or operation at a surgical site and to remove or reduce smoke particles generated during the surgical procedure or operation.

Abstract: The present specification discloses methods and systems for automatically processing an electronic data structure by receiving the electronic data structure that has categories associated therewith, determining, for a first subset of the categories, to automatically update a first set of states associated with the electronic data structure without routing the electronic data structure to a stakeholder, and determining, for a second subset of the categories, to route the electronic data structure to at least one stakeholder. After routing a portion of the electronic data structure to at least one stakeholder and receiving input from that stakeholder, a second set of states is updated based upon the received input and data is generated that is visually representative of each of the first set of states and second set of states.

Abstract: A catheter system for treating a treatment site includes an energy source, a balloon, an energy guide, and a pressure sensor. The balloon is positionable substantially adjacent to the treatment site. The balloon has a balloon wall that defines a balloon interior that receives a balloon fluid. The energy source generates energy that is received by the energy guide so that the energy guide can guide the light energy into the balloon interior. The pressure sensor senses a balloon pressure of the balloon fluid.

Abstract: Twisted pair communication cables that include reduced or minimal use of colorant may include a plurality of twisted pairs of individually insulated conductors, and the respective insulation formed around each conductor may be free of colorant. Additionally, physical indicia may be selectively formed on the respective insulation of at least two of the plurality of twisted pairs, and the physical indicia may facilitate identification of the plurality of twisted pairs. A jacket may be formed around the plurality of twisted pairs.

Abstract: Twisted pair communication cables that include reduced or minimal use of colorant may include a plurality of twisted pairs of individually insulated conductors, and the respective insulation formed around each conductor may not be blended or compounded with any colorant. A separator may be positioned between at least two of the plurality of twisted pairs, and the separator may include one or more physical indicia that facilitate identification of the plurality of twisted pairs. A jacket may be formed around the plurality of twisted pairs and the separator.

Abstract: Twisted pair communication cables that include reduced or minimal use of colorant may include a plurality of twisted pairs of individually insulated conductors, and the respective insulation formed around each conductor included in the plurality of twisted pairs may include one or more polymeric materials that are not blended or compounded with any colorant. Individual shield layers may be provided for two or more of the plurality of twisted pairs. Physical indicia may be selectively formed on at least two of the shield layers, and the physical indicia may facilitate identification of the plurality of twisted pairs. Additionally, a jacket may be formed around the plurality of twisted pairs and the shield layers.