Patents by Inventor Christopher D. Wilsey

Christopher D. Wilsey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10408784
    Abstract: The concentration of glucose in a blood sample is determined by methods utilizing test strips having a sample receiving cavity having a volume from about 0.3 ?l to less than 1 ?l and determining the glucose concentration within a time period from about 3.5 seconds to about 8 seconds.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: September 10, 2019
    Assignees: Roche Diabetes Care, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Patent number: 10386322
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes from about 0.3 ?l to less than 1 ?l and test times from about 3.5 to about 6 seconds after detection of the sample. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: August 20, 2019
    Assignee: ROCHE DIABETES CARE, INC.
    Inventor: Christopher D. Wilsey
  • Publication number: 20170328858
    Abstract: The concentration of glucose in a blood sample is determined by methods utilizing test strips having a sample receiving cavity having a volume from about 0.3 ?l to less than 1 ?l and determining the glucose concentration within a time period from about 3.5 seconds to about 8 seconds.
    Type: Application
    Filed: May 2, 2017
    Publication date: November 16, 2017
    Applicants: Roche Diabetes Care, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Publication number: 20170248538
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes from about 0.3 ?l to less than 1 ?l and test times from about 3.5 to about 6 seconds after detection of the sample. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: May 17, 2017
    Publication date: August 31, 2017
    Applicants: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Patent number: 9658183
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes from about 0.3 ?l to less than 1 ?l and test times from about 3.5 to about 6 seconds after detection of the sample. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: May 23, 2017
    Assignees: Roche Diabetes Care, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Patent number: 9638658
    Abstract: The concentration of glucose in a blood sample is determined by methods utilizing test strips having a sample receiving cavity having a volume from about 0.3 ?l to less than 1 ?l and determining the glucose concentration within a time period from about 3.5 seconds to about 8 seconds.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: May 2, 2017
    Assignees: Roche Diabetes Care, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Patent number: 9416397
    Abstract: Reagent materials and associated test elements are provided. In one embodiment, a test element having dual functionality includes a first coenzyme-dependent enzyme or a substrate for the first enzyme, a second coenzyme-dependent enzyme or a substrate for the second enzyme, and a coenzyme selected from the group consisting of thio-NAD, thio-NADP, and a compound according to formula (I). In one aspect, the first analyte is hydroxybutyrate and the first enzyme is a hydroxybutyrate dehydrogenase, and the second analyte is glucose and the second enzyme is a glucose dehydrogenase or a glucose oxidase. Other aspects of the subject application are directed to unique reagent materials. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description and drawings.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: August 16, 2016
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Christopher D. Wilsey
  • Publication number: 20150226694
    Abstract: The concentration of glucose in a blood sample is determined by methods utilizing test strips having a sample receiving cavity having a volume from about 0.3 ?l to less than 1 ?l and determining the glucose concentration within a time period from about 3.5 seconds to about 8 seconds.
    Type: Application
    Filed: April 24, 2015
    Publication date: August 13, 2015
    Inventor: Christopher D. Wilsey
  • Publication number: 20150226693
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes from about 0.3 ?l to less than 1 ?l and test times from about 3.5 to about 6 seconds after detection of the sample. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: April 24, 2015
    Publication date: August 13, 2015
    Inventor: Christopher D. Wilsey
  • Publication number: 20150140584
    Abstract: Reagent materials and associated test elements are provided. In one embodiment, a test element having dual functionality includes a first coenzyme-dependent enzyme or a substrate for the first enzyme, a second coenzyme-dependent enzyme or a substrate for the second enzyme, and a coenzyme selected from the group consisting of thio-NAD, thio-NADP, and a compound according to formula (I). In one aspect, the first analyte is hydroxybutyrate and the first enzyme is a hydroxybutyrate dehydrogenase, and the second analyte is glucose and the second enzyme is a glucose dehydrogenase or a glucose oxidase. Other aspects of the subject application are directed to unique reagent materials. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description and drawings.
    Type: Application
    Filed: November 21, 2014
    Publication date: May 21, 2015
    Inventor: Christopher D. Wilsey
  • Patent number: 9017544
    Abstract: The concentration of glucose in a blood sample is determined by methods utilizing test strips having a sample receiving cavity having a volume from about 0.3 ?l to less than 1 ?l and determining the glucose concentration within a time period from about 3.5 seconds to about 8 seconds.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: April 28, 2015
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Patent number: 9017543
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes from about 0.3 ?l to less than 1 ?l and test times from about 3.5 to about 6 seconds after detection of the sample. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: April 28, 2015
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Patent number: 8921061
    Abstract: Reagent materials and associated test elements are provided. In one embodiment, a test element having dual functionality includes a first coenzyme-dependent enzyme or a substrate for the first enzyme, a second coenzyme-dependent enzyme or a substrate for the second enzyme, and a coenzyme selected from the group consisting of thio-NAD, thio-NADP, and a compound according to formula (I). In one aspect, the first analyte is hydroxybutyrate and the first enzyme is a hydroxybutyrate dehydrogenase, and the second analyte is glucose and the second enzyme is a glucose dehydrogenase or a glucose oxidase. Other aspects of the subject application are directed to unique reagent materials. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description and drawings.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: December 30, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Christopher D. Wilsey
  • Patent number: 8771793
    Abstract: Systems, apparatuses, techniques and processes for applying a wet film to a substrate using a slot die are provided. In one form, the air pressure around at least a portion of the discharge end of the slot die is adjustable by the application of a vacuum force in order to control the width and thickness of the wet film being applied to the substrate. In one aspect of this form, the wet film is a narrow, continuous stripe of reagent material applied to a moving web of the substrate from which a plurality of test elements will be obtained. However, different forms and applications are also envisioned.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: July 8, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Christopher D. Wilsey, Abner D. Joseph, Sergio Buccilli
  • Publication number: 20140127728
    Abstract: Reagent materials and associated test elements are provided. In one embodiment, a test element having dual functionality includes a first coenzyme-dependent enzyme or a substrate for the first enzyme, a second coenzyme-dependent enzyme or a substrate for the second enzyme, and a coenzyme selected from the group consisting of thio-NAD, thio-NADP, and a compound according to formula (I). In one aspect, the first analyte is hydroxybutyrate and the first enzyme is a hydroxybutyrate dehydrogenase, and the second analyte is glucose and the second enzyme is a glucose dehydrogenase or a glucose oxidase. Other aspects of the subject application are directed to unique reagent materials. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description and drawings.
    Type: Application
    Filed: November 2, 2012
    Publication date: May 8, 2014
    Applicant: Roche Diagnostics Operations, Inc.
    Inventor: Christopher D. Wilsey
  • Publication number: 20140008245
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.0 ?l and test times within about eight seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: December 19, 2012
    Publication date: January 9, 2014
    Inventor: Christopher D. Wilsey
  • Publication number: 20130284610
    Abstract: The concentration of glucose in a blood sample is determined by methods utilizing test strips having a sample receiving cavity having a volume of less than 1 ?l and determining the glucose concentration within a time period of less than 10 seconds.
    Type: Application
    Filed: June 27, 2013
    Publication date: October 31, 2013
    Inventor: Christopher D. Wilsey
  • Patent number: 8535511
    Abstract: A chemistry matrix for use in determining the concentration of an analyte in a biological fluid includes a glucose dehydrogenase, nicotinamide adenine dinucleotide, an alkylphenazine quaternary salt, and/or a nitrosoaniline. The chemistry matrix is used with an electrochemical biosensor to determine the concentration of an analyte after a reaction occurs within the biosensor, at which time an analysis is completed to determine the concentration. A method of determining the concentration of an analyte using the chemistry matrix of glucose dehydrogenase, nicotinamide adenine dinucleotide, an alkylphenazine quaternary salt, and/or a nitrosoaniline is another aspect that is described. The method also further features test times of five seconds or less. Methods utilizing the new chemistry matrix can readily determine an analyte such as blood glucose at concentrations of from about 20-600 mg/dL at a pH of from about 6.5 to about 8.5.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: September 17, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Christopher D. Wilsey, Mitali Ghoshal, Herbert Wieder
  • Publication number: 20130228473
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of up to 1.0 ?l and test times from about 4 to about 9 seconds after detection of the sample. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: April 4, 2013
    Publication date: September 5, 2013
    Inventor: Christopher D. Wilsey
  • Patent number: 8425759
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of up to 1.0 ?l and test times from about 4 to about 9 seconds after detection of the sample. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: April 23, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventor: Christopher D. Wilsey