Patents by Inventor Christopher D. Wilsey

Christopher D. Wilsey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8349168
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.0 ?l and test times within about eight seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: January 8, 2013
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Patent number: 8329026
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.0 ?l and test times within about eight seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: December 11, 2012
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Patent number: 8303801
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.0 ?l and test times within about nine seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: November 6, 2012
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Patent number: 8298401
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.0 ?l and test times within about six seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: October 30, 2012
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventor: Christopher D. Wilsey
  • Publication number: 20120263879
    Abstract: Systems, apparatuses, techniques and processes for applying a wet film to a substrate using a slot die are provided. In one form, the air pressure around at least a portion of the discharge end of the slot die is adjustable by the application of a vacuum force in order to control the width and thickness of the wet film being applied to the substrate. In one aspect of this form, the wet film is a narrow, continuous stripe of reagent material applied to a moving web of the substrate from which a plurality of test elements will be obtained. However, different forms and applications are also envisioned.
    Type: Application
    Filed: April 15, 2011
    Publication date: October 18, 2012
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Christopher D. Wilsey, Abner D. Joseph, Sergio Buccilli
  • Publication number: 20120186996
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.0 ?l and test times within about eight seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: March 29, 2012
    Publication date: July 26, 2012
    Inventor: Christopher D. Wilsey
  • Publication number: 20120181187
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.0 ?l and test times within about six seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: March 28, 2012
    Publication date: July 19, 2012
    Inventor: Christopher D. Wilsey
  • Publication number: 20120181188
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.0 ?l and test times within about eight seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: March 29, 2012
    Publication date: July 19, 2012
    Inventor: Christopher D. Wilsey
  • Publication number: 20120103833
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.0 ?l and test times within about nine seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: December 29, 2011
    Publication date: May 3, 2012
    Inventor: Christopher D. Wilsey
  • Publication number: 20120103834
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of up to 1.0 ?l and test times from about 4 to about 9 seconds after detection of the sample. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: January 11, 2012
    Publication date: May 3, 2012
    Inventor: Christopher D. Wilsey
  • Publication number: 20110290670
    Abstract: A chemistry matrix for use in determining the concentration of an analyte in a biological fluid includes a glucose dehydrogenase, nicotinamide adenine dinucleotide, an alkylphenazine quaternary salt, and/or a nitrosoaniline. The chemistry matrix is used with an electrochemical biosensor to determine the concentration of an analyte after a reaction occurs within the biosensor, at which time an analysis is completed to determine the concentration. A method of determining the concentration of an analyte using the chemistry matrix of glucose dehydrogenase, nicotinamide adenine dinucleotide, an alkylphenazine quaternary salt, and/or a nitrosoaniline is another aspect that is described. The method also further features test times of five seconds or less. Methods utilizing the new chemistry matrix can readily determine an analyte such as blood glucose at concentrations of from about 20-600 mg/dL at a pH of from about 6.5 to about 8.5.
    Type: Application
    Filed: August 12, 2011
    Publication date: December 1, 2011
    Inventors: Christopher D. Wilsey, Mitali Ghoshal, Herbert Wieder
  • Patent number: 8008037
    Abstract: A chemistry matrix for use in determining the concentration of an analyte in a biological fluid includes a glucose dehydrogenase, nicotinamide adenine dinucleotide, an alkylphenazine quaternary salt, and/or a nitrosoaniline. The chemistry matrix is used with an electrochemical biosensor to determine the concentration of an analyte after a reaction occurs within the biosensor, at which time an analysis is completed to determine the concentration. A method of determining the concentration of an analyte using the chemistry matrix of glucose dehydrogenase, nicotinamide adenine dinucleotide, an alkylphenazine quaternary salt, and/or a nitrosoaniline is another aspect that is described. The method also further features test times of five seconds or less. Methods utilizing the new chemistry matrix can readily determine an analyte such as blood glucose at concentrations of from about 20-600 mg/dL at a pH of from about 6.5 to about 8.5.
    Type: Grant
    Filed: March 27, 2008
    Date of Patent: August 30, 2011
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Christopher D. Wilsey, Mitali Ghoshal, Herbert Wieder
  • Patent number: 7879618
    Abstract: The present invention concerns a reagent coating mass which can be used in slot-die-coating of flat support materials in the manufacturing processes of test strips. Advantageously, the reagent mass of the invention exhibits certain superior rheological properties such as viscosity, surface tension and thixotropy. The reagent mass is preferably used to coat thin, narrow and homogeneous stripes of reagent material onto flat web material.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: February 1, 2011
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.
    Inventors: Dan Mosoiu, Christopher D. Wilsey
  • Patent number: 7749437
    Abstract: The present invention concerns a reagent coating mass which can be used in slot-die-coating of flat support materials in the manufacturing processes of test strips. Advantageously, the reagent mass of the invention exhibits certain superior rheological properties such as viscosity, surface tension and thixotropy. The reagent mass is preferably used to coat thin, narrow and homogeneous stripes of reagent material onto flat web material.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: July 6, 2010
    Assignees: Roche Diagnostics Operations, Inc., Roche Operations, Ltd.
    Inventors: Dan Mosoiu, Christopher D. Wilsey
  • Publication number: 20090242428
    Abstract: Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.5 ?l and test times within ten seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.
    Type: Application
    Filed: June 3, 2009
    Publication date: October 1, 2009
    Inventor: Christopher D. Wilsey
  • Publication number: 20090246808
    Abstract: A chemistry matrix for use in determining the concentration of an analyte in a biological fluid includes a glucose dehydrogenase, nicotinamide adenine dinucleotide, an alkylphenazine quaternary salt, and/or a nitrosoaniline. The chemistry matrix is used with an electrochemical biosensor to determine the concentration of an analyte after a reaction occurs within the biosensor, at which time an analysis is completed to determine the concentration. A method of determining the concentration of an analyte using the chemistry matrix of glucose dehydrogenase, nicotinamide adenine dinucleotide, an alkylphenazine quaternary salt, and/or a nitrosoaniline is another aspect that is described. The method also further features test times of five seconds or less. Methods utilizing the new chemistry matrix can readily determine an analyte such as blood glucose at concentrations of from about 20-600 mg/dL at a pH of from about 6.5 to about 8.5.
    Type: Application
    Filed: March 27, 2008
    Publication date: October 1, 2009
    Inventors: Christopher D. Wilsey, Mitali Ghoshal, Herbert Wieder
  • Publication number: 20090162532
    Abstract: The present invention concerns a reagent coating mass which can be used in slot-die-coating of flat support materials in the manufacturing processes of test strips. Advantageously, the reagent mass of the invention exhibits certain superior rheological properties such as viscosity, surface tension and thixotropy. The reagent mass is preferably used to coat thin, narrow and homogeneous stripes of reagent material onto flat web material.
    Type: Application
    Filed: January 29, 2009
    Publication date: June 25, 2009
    Inventors: Dan Mosoiu, Christopher D. Wilsey
  • Patent number: 7479211
    Abstract: A method of forming a biosensor is provided in accordance with the present invention. The method includes providing a metallized electrode support substrate and a sensor support, ablating the electrode support substrate to form electrodes, coupling the sensor support substrate to the electrode support substrate, and positioning spaced-apart electrically conductive tracks across the sensor support substrate so that each track is in electrical communication with one electrode.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: January 20, 2009
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Raghbir S. Bhullar, John T. Austera, Brian S. Hill, Christopher D. Wilsey
  • Patent number: 7473398
    Abstract: The present invention relates to a biosensor. The biosensor includes a support substrate having first and second ends, electrodes positioned on the support substrate, the electrodes cooperating with one another to define electrode arrays situated adjacent to the first end, a spacer substrate positioned on the support substrate, and a cover positioned on the spacer substrate. The cover cooperates with the support substrate to define a channel. The channel includes an inlet adjacent to the first end and opposite ends. Each electrode array is positioned in the channel adjacent to one of the ends.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: January 6, 2009
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Raghbir S. Bhullar, Christopher D. Wilsey, John T. Austera, Wolfgang O. L. Reiser
  • Patent number: 7287318
    Abstract: A biosensor is provided that comprises a plate element with a pre-determined reaction zone and a recess positioned adjacent to the reaction zone. The biosensor also comprises a reagent that is positioned on the reaction zone. In preferred embodiments, the recess circumscribes at least a portion of the reaction zone.
    Type: Grant
    Filed: November 7, 2003
    Date of Patent: October 30, 2007
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Raghbir S. Bhullar, Christopher D. Wilsey, Brian S. Hill