Abstract: Systems and methods interconnect cell culture devices and/or fluidic devices by transferring discrete volumes of fluid between devices. A liquid-handling system collects a volume of fluid from at least one source device and deposits the fluid into at least one destination device. In some embodiments, a liquid-handling robot actuates the movement and operation of a fluid collection device in an automated manner to transfer the fluid between the at least one source device and the at least one destination device. In some cases, the at least one source device and the at least one destination device are cell culture devices. The at least one source device and the at least one destination device may be microfluidic or non-microfluidic devices. In some cases, the cell culture devices may be microfluidic cell culture devices. In further cases, the microfluidic cell culture devices may include organ-chips.

Abstract: A defect prediction method for a device manufacturing process involving processing a portion of a design layout onto a substrate, the method including: identifying a hot spot from the portion of the design layout; determining a range of values of a processing parameter of the device manufacturing process for the hot spot, wherein when the processing parameter has a value outside the range, a defect is produced from the hot spot with the device manufacturing process; determining an actual value of the processing parameter; determining or predicting, using the actual value, existence, probability of existence, a characteristic, or a combination thereof, of a defect produced from the hot spot with the device manufacturing process.

Abstract: A method and apparatus for forming an apex or an apex in combination with a bead, the method comprising the steps of: winding a strip of rubber onto a rotatable platen to form an apex, wherein the rotatable platen may further include a radially expandable bead chuck for supporting a bead. The rotatable platen may optionally include a nonstick coating such as titanium nitride and optionally include one or more radially oriented bars. The optional one or more radially oriented bars may be movable into a first position flush with the outer surface of the platen, and movable into a second position that preferably is nonflush and protrudes from the outer surface of the platen. The rotatable platen is further optionally retractable from the bead chuck to facilitate removal of the apex from the apparatus.

Abstract: An additive manufacturing apparatus can include a stage configured to hold one or more cured layers of resin that form a component. A radiant energy device can be operable to generate and project radiant energy in a patterned image. An actuator can be configured to change a relative position of the stage relative to the radiant energy device. A reclamation system can be downstream of the stage and can be configured to remove at least a portion of the resin from a resin support. The reclamation system can include a first collection structure configured to accept a resin support along a resin support movement direction. A first scraper is positioned within the first collection structure. The first scraper has an elongation axis that is offset from the resin support movement direction by an offset angle that is less than 90 degrees.

Abstract: A method includes providing, via a user interface (UI) of a first application on a first screen device, a UI element prompting a user to connect the first screen device with a second screen device that is presenting a video to the user. The method further includes receiving, via the UI element, an indication of a user request to connect the first screen device with the second screen device. In response to receiving the indication of the user request to connect the first screen device with the second screen device, the method further includes causing the first screen device to be paired with the second screen device. The method further includes providing, for presentation in the UI of the first application of the first screen device, on or more comments provided by one or more other users for the video that is concurrently presented on the second screen device.

Abstract: Organs-on-chips are microfluidic devices for culturing living cells in micrometer sized chambers in order to model physiological functions of tissues and organs. Engineered patterning and continuous fluid flow in these devices has allowed culturing of intestinal cells bearing physiologically relevant features and sustained exposure to bacteria while maintaining cellular viability, thereby allowing study of inflammatory bowl diseases. However, existing intestinal cells do not possess all physiologically relevant subtypes, do not possess the repertoire of genetic variations, or allow for study of other important cellular actors such as immune cells. Use of iPSC-derived epithelium, including IBD patient-specific cells, allows for superior disease modeling by capturing the multi-faceted nature of the disease.

Abstract: A reclamation system for an additive manufacturing apparatus can include a collection structure configured to remove at least a portion of the resin from a foil. A containment vessel can be configured to retain the resin removed from the foil. A drain can direct the resin from the containment vessel to a reservoir.

Abstract: A pluggable module includes a housing having a top wall including an opening above a module cavity. The pluggable module includes a heat exchange assembly separate and discrete from the housing extending into the module cavity through the opening. The heat exchange assembly includes a thermal bridge having an upper thermal interface and a lower thermal interface. The thermal bridge includes a plurality of interleaved plates arranged in a plate stack with the plates being movable relative to each other in the plate stack. The lower thermal interface is in thermal communication with the electrical component to dissipate heat from the electrical component. The thermal bridge extends through the opening with the upper thermal interface exposed from above for dissipating heat from the heat exchange assembly.

Abstract: A tonneau cover for use on a cargo box of a pick-up truck is provided. The tonneau cover may include at least one panel and a latching assembly located on the at least one panel. The latching assembly selectively secures and releases the at least one panel. The latching assembly includes at least one shoe. The at least one shoe is configured for moving at least a portion of the latching assembly to release the at least one panel. The at least one shoe is movable between an extended use position and a retracted stowed position with respect to the at least one panel. And the at least one shoe is spring biased to its extended use position.

Abstract: The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.

Abstract: A trailer towable compact telehandler having an operator cab with an internal width greater than 700 mm and a curbside weight less than 2950 kg. Also included is a telehandler having a side-mounted engine which extends through a side wall of the chassis and under a lifting arm of the telehandler. Also included is a compact tool carrier having a reduced fore-aft dimension between an attachment plane and a principal pivot member.

Abstract: Described herein are systems and methods for generating a computing network from natural language descriptions of the computing network are provided. In one or more examples, the systems and methods described below can be used harvest publically available (or even privately available) natural language descriptions of a computing network, and convert those descriptions into an operational replica of the described computing network. By harvesting both publically available data, as well as other resources, the systems and methods described herein can allow for an analyst tasked with analyzing a given computing network to generate a fully operational replica of the computing network without having to have direct access to the network. In one or more examples, the analyst can recreate a fully-functional replica of the network to be analyzed based on partial descriptions of the computing network, thereby greatly improving the level of analysis capable of being performed.

Abstract: Various aspects described herein relate to presenting drug dispensing information. Data related to a plurality of dispensing events initiated by one or more employees, of an electronic drug dispensing system can be received. A set of dispensing events of the plurality of dispensing events can be determined as constituting possible misappropriation of drugs by the one or more employees. An alert related to the set of dispensing events can be provided based on determining that the set of dispensing events constitute possible misappropriation of drugs.

Abstract: A system including a steerable mirror, a waveguide, first optics, intermediate optics, and final optics. The system includes a first light path for a foveal image element, the first light path including the first optics, the steerable mirror to steer a position of the foveal image element to a particular orientation, intermediate optics, and the final optics to direct the foveal image element to an in-coupling region of the waveguide. The system further includes a second light path for a field image element, the second light path including final optics.

Abstract: A vent assembly, including a vent flapper and one or more air intake openings formed within the vent flapper, wherein the air intake openings allow air to flow both in and out. The assembly may include a removable cover attachable to the vent flapper, or a tube opening and a vent flapper area, wherein the vent flapper area is at least 65 percent larger than the tube opening. The assembly may have air intake openings hexagonal. The assembly may include a tube configured to attach to one of the concentric cylinders, and the backplate may have a plurality of concentric cylinders arranged in decreasing diameter. The cylinders may be separated by dual-sided score lines and at least one of the cylinders is recessed from the backplate. The assembly may have a removable cover configured to block the openings for air intake formed within the vent flapper.

Abstract: A vent assembly, including a backplate having plurality of concentric cylinders arranged in an order of decreasing diameter, such that the concentric cylinders are separated by score lines and at least one of the cylinders is recessed from the backplate, and a vent flapper. The assembly may include a tube configured to attach to one of the cylinders and one or more tube stoppers to prevent the tube from being over inserted. The assembly may include a face plate, a tooth formed on the backplate, and a tooth receiver is formed on the face plate. The score lines may be dual-sided score lines. The assembly may include the vent flapper having one or more air intake openings formed within the vent flapper, such that the air intake openings allow air to flow both in and out.

Abstract: The present invention is related to the field of microfluidics and compound distribution within microfluidic devices and their associated systems. In one embodiment, present invention aims to solve the problem of molecule and compound absorbency into the materials making up laboratory equipment, microfluidic devices and their related infrastructure, without unduly restricting gas transport within microfluidic devices.

Abstract: A light-emitting user input device can include a touch sensitive portion configured to accept user input (e.g., from a user's thumb) and a light-emitting portion configured to output a light pattern. The light pattern can be used to assist the user in interacting with the user input device. Examples include emulating a multi-degree-of-freedom controller, indicating scrolling or swiping actions, indicating presence of objects nearby the device, indicating receipt of notifications, assisting pairing the user input device with another device, or assisting calibrating the user input device. The light-emitting user input device can be used to provide user input to a wearable device, such as, e.g., a head mounted display device.