Abstract: This disclosure generally relates to transgenic plants that recombinantly express nucleic acid sequences encoding polypeptides capable of upregulating heme biosynthesis, and methods of producing a heme-loaded heme polypeptide.

Abstract: This document relates to methods of making recombinant target products in transgenic plants in a contained system, and more particularly to separating the production of plant biomass from the production of the target product by selectively expressing the target product during germination in a contained system.

Abstract: Safety-blade dispensers for safely storing surgical blades prior to surgery and optionally for retrieving used surgical blades after surgery. In either case, the safety-blade dispenser is configured to store one or more surgical blades in an orientation that allows a user to simply and safely attach a surgical tool handle to the surgical blades (and optionally remove the handle from the surgical blades) without requiring the user to physically touch or manipulate the surgical blades by hand. The safety-blade dispensers disclosed herein may be used alone or in conjunction with a system and method of preventing wrong-site surgery.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for optimizing transmission of digital components. In one aspect a digital component distribution system performs operations including determining a minimum eligibility value required to maintain the eligibility of a given digital component based on a next highest eligibility value of one of the other digital components. Based on the next highest eligibility value, a baseline transmission value required to be submitted for distribution of the given digital component is determined. A normalized transmission value is determined based on the minimum eligibility value, and transmission of the given digital component to a client device presenting a particular electronic document is triggered based on the normalized transmission value.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for distributing content items. In one aspect, a method includes identifying a content item that is eligible to be provided in response to a content item request and is associated with a bid. It is determined that the identified content item includes two or more different interactive elements that each cause different actions to be initiated in response to user interaction with the different interactive elements. An auction score is determined for the content item based on a function of the bid, a bid modifier for each different interaction, and a probability that each interaction will be invoked. The content item is selected to be provided based on the auction score. Data that cause presentation of the selected content item at a user device are output.

Abstract: An system and a method for the detection and reporting of occupational safety incidents are disclosed. The system receives a set of digital records corresponding to reported occupational safety incidents. The system converts each of the digital records from the set of digital records into a common digital format. The system deconstructs the uniform text structure of each digital recorded by a natural language processing module to lemmatize words, remove punctuation, and remove stop words. The system creates a feature vector based on the received deconstructed uniform text structure. The system inputs each feature vector to an ensemble machine learning data model, returning a determination of a possible class or characteristic of occupational safety incident. The system applies a threshold based on a probability to the determination of a possible class. The system submits a subset of the reported occupational safety incidents to a third party system.

Abstract: Apparatus for use in handling windscreens for example for installation in a vehicle, includes a windscreen anchor assembly comprising a windscreen anchor device and a support arm extending away from the windscreen anchor device. A mount assembly is provided for supporting the windscreen anchor assembly. The mount assembly includes a mount structure for engaging with the support arm such that the support arm can slide bodily in its longitudinal direction with respect to the mount structure.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for optimizing transmission of digital components. In one aspect a digital component distribution system performs operations including determining a minimum eligibility value required to maintain the eligibility of a given digital component based on a next highest eligibility value of one of the other digital components. Based on the next highest eligibility value, a baseline transmission value required to be submitted for distribution of the given digital component is determined. A normalized transmission value is determined based on the minimum eligibility value, and transmission of the given digital component to a client device presenting a particular electronic document is triggered based on the normalized transmission value.

Abstract: Materials and methods for extracting and purifying proteins are provided. For example, the materials and methods provided herein can be used for extracting and purifying proteins that denature at low temperature.

Abstract: Compositions and method are therefore disclosed for treating ARDS. In particular, disclosed a composition that contains one, two, or more cytidine diphosphate (CDP)-conjugated precursors selected from the group consisting of CDP-choline, CDP-ethanolamine, and CDP-diacylglycerol (CDP-DAG) in a pharmaceutically acceptable carrier for use in treating ARDS.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for distributing content items. In one aspect, a method includes identifying a content item that is eligible to be provided in response to a content item request and is associated with a bid. It is determined that the identified content item includes two or more different interactive elements that each cause different actions to be initiated in response to user interaction with the different interactive elements. An auction score is determined for the content item based on a function of the bid, a bid modifier for each different interaction, and a probability that each interaction will be invoked. The content item is selected to be provided based on the auction score. Data that cause presentation of the selected content item at a user device are output.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for evaluating digital content. In one aspect, a system includes a distributed computing system that accesses the third-party corpus database to evaluate the various third-party content and transmit, to a user device, digital data that produce visualizations of at least a portion of a set of the various third-party content in a display of the user device. The digital data include instructions that cause presentation of at least some of the visualizations of the various third-party content at the user device according to respective formatting that was selected by the distributed computing system for each of the at least some of the various third-party content.

Abstract: Apparatus for use in handling windscreens for example for installation in a vehicle, includes a windscreen anchor assembly comprising a windscreen anchor device and a support arm extending away from the windscreen anchor device. A mount assembly is provided for supporting the windscreen anchor assembly. The mount assembly includes a mount structure for engaging with the support arm such that the support arm can slide bodily in its longitudinal direction with respect to the mount structure.

Abstract: A method of depositing dissoluble solid material onto a substrate includes providing a supersaturated solution including the solid material dissolved in a solvent, flowing the supersaturated solution out of an orifice of a handheld device and onto the substrate, and activating the supersaturated solution, at ambient temperature, so that the supersaturated solution solidifies. A handheld device for depositing the dissoluble solid material is also described.

Abstract: Use of a polymer as a secondary suspending agent in a suspension polymerization reaction is provided. The polymer comprising (i) residues of at least one ester-containing monomer, the ester-containing monomer (s) comprising one polymerizable carbon-carbon double bond per monomer and an ester group, and (ii) residues of at least one monomer comprising a sulfonate, sulfonic acid, sulfonic ester, sulfonamide or sulfonyl halide group the monomer (s) comprising a sulfonate, sulfonic acid, sulfonic ester group, sulfonamide or sulfonyl halide group comprising one polymerizable carbon-carbon double bond per monomer and a sulfonate, sulfonic acid, sulfonic ester, sulfonamide or sulfonyl halide group, the polymer optionally being partially hydrolyzed such that a proportion of said ester groups form alcohol groups, the degree of hydrolysis of the polymer being from 0 to 30 mol %.

Abstract: The invention provides a method for inhibiting bacterial attachment to a surface, the method comprising forming the surface from a polymer, or applying a polymer to the surface, wherein the polymer is a homopolymer formed from a (meth) acrylate or (meth) acrylamide monomer or a copolymer formed from one or more (meth) acrylate or (meth) acrylamide monomers, wherein the (meth) acrylate or (meth) acrylamide monomers are of formula (I) or (II): [H2C?CR?—C(=0)-0-]n, R (I) [H2C?CR?—C(=0)-NH—]n R (II) wherein n is 1, 2 or 3, R? is independently H or CH3, R is an organic group having a total of from 2 to 24 carbon atoms, wherein the organic group includes an aliphatic or aromatic hydrocarbon moiety and wherein the organic group does not include any hydroxyl groups.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for evaluating digital content. In one aspect, a system includes a distributed computing system that access the third-party corpus database to evaluate the various third-party content, based at least in part on the one or more parameters, and transmit digital data corresponding to a set of the various third-party content to a user device. The evaluation can include a first evaluation process that provides a cost-prominence relationship for various third party content and is used, in part, to select a format for at least some of the third-party content, and a second evaluation process that is used to select locations of an electronic document for at least some of the third-party content. The multiple evaluation processes can be completed in less time than a combinatorial evaluation process.

Abstract: A system and related methods of preventing wrong-site surgeries and blade-related injuries to OR personnel, which includes a computer software system (for use on computers or hand-held devices in the medical environment) in combination with a surgical supply carrier (such as a safety blade-dispenser or other surgical sharps dispenser). The surgical supply carrier comprises at least one component, such as a label, which prevents or impedes a surgeon from accessing one or more surgical instruments stored within until after a “time-out” is performed by the surgeon or authorized OR personnel to confirm various details including but not limited to correct patient, correct procedure, correct equipment, etc, before starting the intended surgical procedure. Data can be captured throughout the medical environment (from “decision-to-incision” and beyond) to assess wrong-site surgery data (including “near miss” data) and enable a host of analytics on wrong-site surgery prevention.

Abstract: Materials and methods for extracting and purifying proteins are provided. For example, the materials and methods provided herein can be used for extracting and purifying proteins that denature at low temperature.

Abstract: Materials and methods for extracting and purifying proteins are provided. For example, the materials and methods provided herein can be used for extracting and purifying proteins that denature at low temperature.