Abstract: Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2.

Abstract: The present invention relates to neutralizing antibodies of the human pituitary adenylate cyclase activating polypeptide type I receptor (PAC1) and pharmaceutical compositions comprising such antibodies. Methods of treating or preventing headache conditions, such as migraine and cluster headache, using the neutralizing antibodies are also described.

Abstract: Disclosed are embodiments of battery stacker machines, including z-fold stacker machines, configured to provide a rolling transfer of a battery layer so as to reduce scrubbing. In some embodiments, the layer is flexed onto an arcuate surface using a vacuum or other force. The arcuate surface is then rotated to release the layer at a desired transfer location. For instance, the desired transfer location may be on top of a stack or onto another arcuate gripper surface.

Abstract: An audio session management method may involve: determining, by an audio session manager, one or more first media engine capabilities of a first media engine of a first smart audio device, the first media engine being configured for managing one or more audio media streams received by the first smart audio device and for performing first smart audio device signal processing for the one or more audio media streams according to a first media engine sample clock; receiving, by the audio session manager and via a first application communication link, first application control signals from the first application; and controlling the first smart audio device according to the first media engine capabilities, by the audio session manager, via first audio session management control signals transmitted to the first smart audio device via a first smart audio device communication link and without reference to the first media engine sample clock.

Abstract: Coronavirus S ectodomain trimers stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the coronavirus S ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to coronavirus in a subject. In additional embodiments, the therapeutically effective amount of the coronavirus S ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing coronavirus infection.

Abstract: Systems, computer program products, and methods are described herein for implementing dynamic network channel switching for secure communication. The present invention is configured to receive, from a first user input device, a resource transfer request via a first communication channel; determine, using a secure channel monitoring engine, that the first communication channel does not meet one or more preset channel requirements for secure communication; determine a second communication channel associated with a second user input device, wherein the second user input device is within a preset geographic radius of the first user input device, wherein the second user input device is associated with the resource distribution platform; trigger, via the second communication channel, the second user input device to establish a communication link with the first user input device to form an alternate communication channel; and execute, via the alternate communication channel, the resource transfer request.

Abstract: Systems, computer program products, and methods are described herein for the parallel testing of multiple data processing channels. The present invention may be configured to generate a data packet, send the data packet to a processing channel for processing at a send time, receive the processed data from the processing channel at a return time, determine the percent accuracy for the processed data from the processing channel, and record the send time, return time, and percent accuracy in an analytics system. The present invention may also be configured to determine the security of the processing channel and record the security in the analytics system.

Abstract: Systems, computer program products, and methods are described herein for dynamic communication channel switching based on preconfigured network security protocols.

Abstract: A tunnel is established between a first edge server of a distributed edge compute and routing service and a tunnel client residing on an origin server. Routing rules are installed in the edge servers of the distributed edge compute and routing service to reach the first edge server. The routing rules are based at least in part on traffic information gathered from processing other traffic that traverses the distributed edge compute and routing service. A request for content served by the origin server through the tunnel is received at a second edge server of the distributed edge compute and routing service. A path from the second edge server to the first edge server is determined based on the routing rules. The request is transmitted on the determined path. The first edge server receives the request and transmits the request to the origin server over the tunnel.

Abstract: An attenuation or “gap” may be inserted into at least a first frequency range of at least first and second audio playback signals of a content stream during at least a first time interval to generate at least first and second modified audio playback signals. Corresponding audio device playback sound may be provided by at least first and second audio devices. At least one microphone may detect at least the first audio device playback sound and the second audio device playback sound and may generate corresponding microphone signals. Audio data may be extracted from the microphone signals in at least the first frequency range, to produce extracted audio data. A far-field audio environment impulse response and/or audio environment noise may be estimated based, at least in part, on the extracted audio data.

Abstract: A microfluidic cartridge is provided. The microfluidic cartridge has an interior and an exterior. The microfluidic cartridge includes a reservoir disposed in the interior of the microfluidic cartridge and configured to contain a fluid composition. The microfluidic cartridge includes an electric circuit disposed on the exterior of the microfluidic cartridge. The electric circuit comprises a first end portion having electrical contacts and a second end portion opposing the first end portion. The microfluidic cartridge includes a microfluidic die disposed on the exterior of the microfluidic cartridge, wherein the microfluidic die is electrically connected with the second end portion of the electric circuit and in fluid communication with the reservoir. A silicone pressure-sensitive adhesive is used to join the electric circuit with the exterior of the microfluidic cartridge.

Abstract: Systems and methods for adaptively adjusting a slew rate of a dejitter buffer in a remote device in a distributed access architecture. The slew rate may be adjusted based on measurements of a fullness state of a buffer made over time. The measurements may be used to calculate a frequency offset value between the rate at which data leaves the buffer relative to the rate at which data enters the buffer and/or used to calculate a current working depth of the buffer. The adaptive slew rate adjustments may be based on the frequency offset value and/or the current working depth.

Abstract: A hybrid electric vehicle charging station (EVCS) is provided. The EVCS includes a charging chassis that is configured to support a charging circuitry for providing a charge current to an electric vehicle and a multi-conductor cable that is attached to the charging chassis and that receives the charging current from the charging circuitry and that transmits the charging current to the electric vehicle. The EVCS further includes a user interface that is attached to the charging chassis and that is configured to provide digital content to a vehicle operator during a charging event of the electric vehicle. The charging chassis includes multiple user interface attachment structures that are each configured to support the user interface.

Abstract: Software systems and methods convert algorithms and software codes into time affecting linear pathways (TALPs) via decomposition and convert paired Input/Output (I/O) datasets into TALPs via Value Complexity polynomials. Generated TALPs can be enhanced through merging with other TALPs. TALPs can be grouped by matching the outputs of the TALP-associated prediction polynomials with some set of given criteria into families and cross-families that are useful in a new type of software optimization that allows for output values of grouped TALPs to be modeled, pooled, discretized and optimized to enhance goals or meet user goals.

Abstract: Some methods may involve receiving a first content stream that includes first audio signals, rendering the first audio signals to produce first audio playback signals, generating first direct sequence spread spectrum (DSSS) signals, generating first modified audio playback signals by inserting the first DSSS signals into the first audio playback signals, and causing a loudspeaker system to play back the first modified audio playback signals, to generate first audio device playback sound. The method(s) may involve receiving microphone signals corresponding to at least the first audio device playback sound and to second through Nth audio device playback sound corresponding to second through Nth modified audio playback signals (including second through Nth DSSS signals) played back by second through Nth audio devices, extracting second through Nth DSSS signals from the microphone signals and estimating at least one acoustic scene metric based, at least partly, on the second through Nth DSSS signals.

Abstract: Some methods may involve receiving a first content stream that includes first audio signals, rendering the first audio signals to produce first audio playback signals, generating first direct sequence spread spectrum (DSSS) signals, generating first modified audio playback signals by inserting the first DSSS signals into the first audio playback signals, and causing a loudspeaker system to play back the first modified audio playback signals, to generate first audio device playback sound. The method(s) may involve receiving microphone signals corresponding to at least the first audio device playback sound and to second through Nth audio device playback sound corresponding to second through Nth modified audio playback signals (including second through Nth DSSS signals) played back by second through Nth audio devices, extracting second through Nth DSSS signals from the microphone signals and estimating at least one acoustic scene metric based, at least partly, on the second through Nth DSSS signals.

Abstract: The present disclosure relates to methods and apparatus for processing media content having video content and associated audio content. A method of processing media content having video content and associated audio content comprises the method includes receiving the video content and the associated audio content, analyzing the associated audio content, determining one or more navigation points for enabling navigation of the media content based on the analysis, wherein the one or more navigation points indicate points of interest in the associated audio content for short-term rewinding and/or fast forwarding, embedding the one or more navigation points into metadata for the media content, and outputting the video content, the associated audio content, and the metadata.

Abstract: Software systems and methods convert algorithms and software codes into time affecting linear pathways (TALPs) via decomposition and convert paired Input/Output (I/O) datasets into TALPs via Value Complexity polynomials. Generated TALPs can be enhanced through merging with other TALPs. TALPs can be grouped by matching the outputs of the TALP-associated prediction polynomials with some set of given criteria into families and cross-families that are useful in a new type of software optimization that allows for output values of grouped TALPs to be modeled, pooled, discretized and optimized to enhance goals or meet user goals.

Abstract: Some implementations involve receiving, from a first subband domain acoustic echo canceller (AEC) of a first audio device in an audio environment, first adaptive filter management data from each of a plurality of first adaptive filter management modules, each first adaptive filter management module corresponding to a subband of the first subband domain AEC, each first adaptive filter management module being configured to control a first plurality of adaptive filters. The first plurality of adaptive filters may include at least a first adaptive filter type and a second adaptive filter type. Some implementations involve extracting, from the first adaptive filter management data, a first plurality of extracted features corresponding to a plurality of subbands of the first subband domain AEC and estimating a current local acoustic state based, at least in part, on the first plurality of extracted features.

Abstract: A sensing apparatus can be configured to detect an edge of a paper that is received by an automated transaction machine (ATM). The paper can move along a path located inside the ATM, the path having opposite first and second sides. The sensing apparatus can include a light emitter and a light detector on the first side of the path, with the light emitter positioned so that it can emit light across the path to the second side. The light detector can be configured to detect light from the light emitter and can emit a signal corresponding to an amount of detected light. The sensing apparatus can also include a control circuit that can control a flow of power to the light emitter, and the control circuit can also receive the signal emitted by the sensor.