Abstract: In an auto vibrancy mode, a vibrancy value for a lighting load may be automatically determined based on a selected color setting for the lighting load. The automatically determined vibrancy value may also be configured to emit light from the lighting load at or above a target CRI value for the selected color setting. The selected color setting may be a CCT value on the black-body curve or an x-y chromaticity value. If the selected color setting is CCT value on the black-body curve, the automatically determined vibrancy value may be a pre-defined vibrancy value that is configured to emit light from the lighting load at or above the target CRI value for the selected CCT value. If the selected color setting is an x-y chromaticity value, the automatically determined vibrancy value may be based on the distance between the selected x-y chromaticity value and the black-body curve.

Abstract: The lighting device may be configured to perform black body curve fading. For example, the control circuit may be configured to control the drive circuit such that the light emitted by the lighting load is adjusted (e.g., faded) along a black body curve. The control circuit may be configured to determine whether to fade from an initial color to a destination color in a Correlated Color Temperature (CCT) chromaticity space or an XY chromaticity space. The control circuit may be configured to determine whether the initial color and/or the destination color are on the black body curve. When the initial color and the destination color are determined to be on the black body curve, the control circuit may be configured to control the drive circuit such that the light emitted by the lighting device is adjusted from the initial color to the destination color along the black body curve.

Abstract: Quantum dots (QDs) and nanoplatelets (NPLs) are two types of nanoparticles used as scaffolds for enzymes operating in enzymatic cascades. Combinations of QDs and NPLs were surprisingly found to operate synergistically to create a greater enhancement than either alone when operating as scaffolds for enzymatic cascade reactions. A process involves providing an enzymatic cascade including a cluster of nanoparticles including both QDs and NPLs and having a plurality of enzymes bound thereto, the enzymes configured as an enzymatic cascade, such that the product of a first enzyme is a substrate of a second enzyme; contacting the cascade cluster with a substrate of the first enzyme; and allowing a reaction to proceed so that each of the plurality of enzymes acts in succession to produce an end product. The enzymes are bound to the nanoparticles via metal affinity coordination between histidine tags on the enzymes and zinc-containing surfaces of the nanoparticles.

Abstract: A system includes an aqueous solution containing a positively charged peptide, a molecular counterion thereto, and a molecular beacon. The molecular beacon includes a DNA construct including single-stranded DNA tending to form a hairpin (HP) configuration and having (1) a central loop region complementary to a target sequence, (2) regions at opposing ends complementary to one another, and (3) a fluorophore and a quencher thereof at the opposing ends, such that binding with the target sequence results in dissociation of the DNA regions at the opposing ends, thereby separating the fluorophore and quencher with a resulting increase in fluorescence. The system may be useful in nucleotide detection methods.

Abstract: In an auto vibrancy mode, a vibrancy value for a lighting load may be automatically determined based on a selected color setting for the lighting load. The automatically determined vibrancy value may also be configured to emit light from the lighting load at or above a target CRI value for the selected color setting. The selected color setting may be a CCT value on the black-body curve or an x-y chromaticity value. If the selected color setting is CCT value on the black-body curve, the automatically determined vibrancy value may be a pre-defined vibrancy value that is configured to emit light from the lighting load at or above the target CRI value for the selected CCT value. If the selected color setting is an x-y chromaticity value, the automatically determined vibrancy value may be based on the distance between the selected x-y chromaticity value and the black-body curve.

Abstract: A lighting device may include an elongated housing that defines a cavity. The lighting device may include plurality of emitter printed circuit boards configured to be received within the cavity. Each of the plurality of emitter printed circuit boards may include a plurality of emitter modules mounted thereto. Each of the plurality of emitter printed circuit boards may include a control circuit configured to control the plurality of emitter modules mounted to the respective emitter printed circuit board based on receipt of one or more messages. The lighting device may include a total internal reflection lens for each of the plurality of emitter printed circuit boards. The total internal reflection lens may be configured to diffuse light emitted by the emitter modules of the plurality of emitter printed circuit boards.

Abstract: A linear lighting device may include an elongated housing that defines a cavity. The linear lighting device may include plurality of emitter printed circuit boards configured to be received within the cavity. Each of the plurality of emitter printed circuit boards may include a plurality of emitter modules mounted thereto. Each of the plurality of emitter printed circuit boards may include a control circuit configured to control the plurality of emitter modules mounted to the respective emitter printed circuit board based on receipt of one or more messages. The linear lighting device may include a total internal reflection lens for each of the plurality of emitter printed circuit boards. The total internal reflection lens may be configured to diffuse light emitted by the emitter modules of the plurality of emitter printed circuit boards.

Abstract: A lighting device may include an elongated housing that defines a cavity. The lighting device may include plurality of emitter printed circuit boards configured to be received within the cavity. Each of the plurality of emitter printed circuit boards may include a plurality of emitter modules mounted thereto. Each of the plurality of emitter printed circuit boards may include a control circuit configured to control the plurality of emitter modules mounted to the respective emitter printed circuit board based on receipt of one or more messages. The lighting device may include a total internal reflection lens for each of the plurality of emitter printed circuit boards. The total internal reflection lens may be configured to diffuse light emitted by the emitter modules of the plurality of emitter printed circuit boards.

Abstract: A linear lighting device may include an elongated housing that defines a cavity. The linear lighting device may include plurality of emitter printed circuit boards configured to be received within the cavity. Each of the plurality of emitter printed circuit boards may include a plurality of emitter modules mounted thereto. Each of the plurality of emitter printed circuit boards may include a control circuit configured to control the plurality of emitter modules mounted to the respective emitter printed circuit board based on receipt of one or more messages. The linear lighting device may include a total internal reflection lens for each of the plurality of emitter printed circuit boards. The total internal reflection lens may be configured to diffuse light emitted by the emitter modules of the plurality of emitter printed circuit boards.

Abstract: One can enrich nucleic acid (RNA or DNA) from within a complex mixture in a sequence-specific manner by using a mutant of a Cas enzyme lacking nuclease activity, for example a mutant of Cas13a (dCas) from Leptotrichia wadeii. The nucleic acid is bound by the mutant protein as directed by guide RNA molecules (crRNA) and purified after association with an appropriate surface, such as quantum dots or functionalized beads. The nucleic acid is separated from the Cas and purified after precipitation or interaction with another surface. The resulting product can be directly processed via long-read sequencing.

Abstract: Systems and methods are disclosed for communicating via a communications network with a load control system of a respective user environment, receiving information on the load control system via the communications network, displaying graphical user interfaces based on the received information, and controlling and configuring the load control system via graphical user interfaces by communicating via the communications network messages the load control system.

Abstract: A system may include a plurality of master lighting modules and a fixture controller. The fixture control may include a power converter circuit that is configured to generate a bus voltage on a power bus. The plurality of master lighting modules may be serially-coupled on the power bus. The fixture controller may include a control circuit that is configured to receive an indication of a magnitude of an end bus voltage at an end master lighting module. The end master lighting module may be the master lighting module that is located furthest from the fixture controller along the power bus. The control circuit may be configured to generate a target bus voltage control signal based on the magnitude of the end bus voltage. The power converter circuit may be configured to control a magnitude of the bus voltage based on the target bus voltage control signal.

Abstract: Systems and methods are disclosed for communicating via a communications network with a load control system of a respective user environment, receiving information on the load control system via the communications network, displaying graphical user interfaces based on the received information, and controlling and configuring the load control system via graphical user interfaces by communicating via the communications network messages the load control system.

Abstract: A flexible strategy for assembling luminescent and colorimetric quantum dot/nucleic acid hairpin (QD-HP) molecular beacons for use in CRISPR/Cas diagnostics uses chimeric peptide/peptide nucleic acid (PNA) to conjugate fluorescently labeled DNA or RNA hairpins to ZnS-coated QDs.