Abstract: A negative pressure wound therapy system includes at least one sensor coupled to a wound dressing for a wound of a patient, and a control circuit. The at least one sensor is configured to output an indication of a displacement of the wound dressing. The control circuit is configured to receive the indication of the displacement of the wound dressing, calculate a therapy parameter corresponding to the indication of the displacement, and output the therapy parameter.

Abstract: Devices and methods for improving voltage handling and/or bi-directionality of stacks of elements when connected between terminals are described. Such devices and method include use of symmetrical compensation capacitances, symmetrical series capacitors, or symmetrical sizing of the elements of the stack.

Abstract: Systems, methods, and apparatuses for treating a tissue site are described. In some embodiments, the system may include a pouch having an upstream layer, a downstream layer, and an absorbent member enclosed between the upstream layer and the downstream layer. The upstream layer and the downstream layer may each include a hydrophobic side and a hydrophilic side. The hydrophilic side of both the upstream layer and the downstream layer may be positioned facing the absorbent member. The hydrophobic side of both the upstream layer and the downstream layer may form a portion of an exterior surface of the pouch such that fluid incident on the pouch is distributed laterally along the exterior surface of the pouch before being absorbed by the absorbent member.

Abstract: An encapsulation method is disclosed for the capture of natural flavors within a clean-label derived from a malt comprising at least partially germinated whole grain seed, pulses, legumes, false grains or flour derived therefrom. Moreover, a spray dryable malted rice composition is disclosed that has rice present at an amount that is at least about 30% by weight.

Abstract: In some embodiments, a dressing assembly may include a dressing bolster, an interface seal, and a base layer. The dressing bolster may include a first side, a second side, and a periphery. The interface seal may be coupled at the periphery of the dressing bolster. The base layer may include a base layer flange configured to be coupled to the dressing and to extend beyond the periphery of the dressing bolster. The dressing assembly may be suitable for treating a tissue site with reduced pressure and for creating an apposition force between a first portion of the tissue site and a second portion of the tissue site. Other systems, apparatus, and methods are disclosed.

Abstract: Bias circuits and methods for silicon-based amplifier architectures that are tolerant of supply and bias voltage variations, bias current variations, and transistor stack height, and compensate for poor output resistance characteristics. Embodiments include power amplifiers and low-noise amplifiers that utilize a cascode reference circuit to bias the final stages of a cascode amplifier under the control of a closed loop bias control circuit. The closed loop bias control circuit ensures that the current in the cascode reference circuit is approximately equal to a selected multiple of a known current value by adjusting the gate bias voltage to the final stage of the cascode amplifier. The final current through the cascode amplifier is a multiple of the current in the cascode reference circuit, based on a device scaling factor representing the relative sizes of the transistor devices in the cascode amplifier and in the cascode reference circuit.

Abstract: A treatment apparatus which uses thermal or non-thermal plasma to treat urinary tract infections (UTIs) by destroying bacteria. The apparatus comprises an elongate probe that includes a coaxial cable for conveying radiofrequency (RF) electromagnetic (EM) energy and/or microwave EM energy, a probe tip connected at the distal end of the coaxial cable for receiving the RF and/or microwave EM energy, and a gas conduit for conveying gas to the probe tip. The probe tip comprises a first electrode connected to the inner conductor of the coaxial cable, and a second electrode connected to the outer conductor of the coaxial cable, and wherein the first electrode and second electrode are arranged to produce an electric field from the received RF and/or microwave EM energy across a flow path of gas received from the gas conduit to produce a thermal or a non-thermal plasma.

Abstract: Systems, methods, and apparatuses for debriding a tissue site are described. The system includes a manifold and a cover adapted to form a sealed space over the tissue site for providing negative pressure. The system also includes a debridement tool positioned between the manifold and the tissue site. The debridement tool having a tissue-facing surface and a plurality of holes separated from each other by walls. The walls have transverse surfaces extending between the tissue-facing surface and an opposite surface that form cutting edges. The holes have a perforation shape factor that allows the holes to collapse from a relaxed position to a contracted position in response to the application and removal of negative pressure from the sealed space. The cutting edges debride the tissue site in response to movement between the relaxed position and the contracted position.

Abstract: A vertical door latch assembly includes a housing and a bolt movably attached to the housing having a catch portion. A drive motor is located within the housing and is configured to selectively move a lock assembly between a locked position preventing movement of the bolt and an unlocked position allowing movement of the bolt. A controller is in electrical communication with the drive motor and is configured to direct the actuator lock assembly between the locked position and the unlocked position. A force sensor is in electrical communication with the controller configured to measured when a force exceeds a predetermined threshold.

Abstract: Integrated circuits (ICs) that avoid or mitigate creation of changes in accumulated charge in a silicon-on-insulator (SOI) substrate, particularly an SOI substrate having a trap rich layer. In one embodiment, a FET is configured such that, in a standby mode, the FET is turned OFF while maintaining essentially the same VDS as during an active mode. In another embodiment, a FET is configured such that, in a standby mode, current flow through the FET is interrupted while maintaining essentially the same VGS as during the active mode. In another embodiment, a FET is configured such that, in a standby mode, the FET is switched into a very low current state (a “trickle current” state) that keeps both VGS and VDS close to their respective active mode operational voltages. Optionally, S-contacts may be formed in an IC substrate to create protected areas that encompass FETs that are sensitive to accumulated charge effects.

Abstract: Systems, kits, methods of manufacturing, and a sealing member for creating a sealed space are described. The sealing member can include a film layer and a first adhesive layer coupled to the film layer. The sealing member can also include a second adhesive layer coupled to the first adhesive layer. A plurality of apertures may extend through the second adhesive layer. Each aperture can expose at least a portion of the first adhesive layer through the second adhesive layer. A plurality of polymer particles may be disposed in the first adhesive layer. The polymer particles can be configured to dissolve in response to interaction with a switching solution.

Abstract: Raw sensor data from a device of a user is collected. Trips from the sensor data are identified as raw trip data. Metadata for the trips is identified, linked to the trips, and maintained separately from the trip data. The trips are staged, and the corresponding trip data normalized when obtained from a storage or memory location. Normalized trip data is piped or made accessible to feature enhancing applications (apps), each app associating one or more features and events with a given trip. The features and events are maintained for the trips in event and feature level of detail tables. The tables are processed by consuming apps for purposes of updating user-level attributes associated with the user. In an embodiment, custom apps process the raw trip data to add additional features and events, which are directly integrated and updated in the tables for access by the consuming apps.

Abstract: In some illustrative examples, a bridge suitable for treating a tissue site may include a bridge sealing member and one or more bridge wicking layers. The bridge sealing member may extend along a length of the bridge, and may define an internal passageway in fluid communication between a receiving end of the bridge and a transmitting end of the bridge. The one or more bridge wicking layers may be disposed within the internal passageway of the bridge sealing member. Other apparatus, systems, and methods are disclosed.

Abstract: Provided are computing systems, methods, and platforms that automatically produce production-ready machine learning models and deployment pipelines from minimal input information such as a raw training dataset. In particular, one example computing system can import a training dataset associated with a user. The computing system can execute an origination machine learning pipeline to perform a model architecture search that selects and trains a machine learning model for the training dataset. Execution of the origination machine learning pipeline can also result in generation of a deployment machine learning pipeline configured to enable deployment of the machine learning model (e.g., running the machine learning model to produce inferences and/or optionally other tasks such as re-training and/or re-tuning the model).

Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.

Abstract: Increasing the chromium content of an electrical steel substrate to a level greater than or equal to about 0.45 weight percent (wt %) produced a much improved forsterite coating having superior and more uniform coloration, thickness and adhesion. Moreover, the so-formed forsterite coating provides greater tension potentially reducing the relative importance of any secondary coating.

Abstract: The technology disclosed herein enables detection of domain hijacking when a DNS resolver is performing a DNS lookup. In a particular embodiment, a method provides, in response to a request to resolve a network address corresponding to a domain name, determining that a nameserver for the domain name is suspect based on satisfaction of nameserver criteria associated with the domain name. The method further includes preventing the nameserver from being used to resolve the request in response to determining that the nameserver is suspect.

Abstract: Provided herein is a system and method for mitigating premature light deactivation of light deactivated adhesive drapes. One aspect provides a system comprising a drape, a photosensitive adhesive layer, a release agent, and an optical fiber mesh layer configured as a light pipe, where the system is adapted to be coupled to a tissue site and released therefrom upon or after exposure to an external stimulus such as certain wavelengths of light. Another aspect includes a pipe light pipe, as an alternative to the optical fiber mesh layer. The systems may have a removable blocking layer to prevent the photosensitive adhesive from being exposed to deactivation wavelengths prematurely. Another aspect provides a method for application and removal of a drape using the light pipe to transport or route light to the drape to deactivate the photosensitive adhesive layer and promote easy, clean, and less painful removal of the drape.

Abstract: A controllable temperature coefficient bias (CTCB) circuit is disclosed. The CTCB circuit can provide a bias to an amplifier. The CTCB circuit includes a variable with temperature (VWT) circuit having a reference circuit and a control circuit. The control circuit has a control output, a first current control element and a second current control element. Each current control element has a “controllable” resistance. One of the two current control elements may have a relatively high temperature coefficient and another a relatively low temperature coefficient. A controllable resistance of one of the current control elements increases when the controllable resistance of the other current control element decreases. However, the “total resistance” of the current control circuit remains constant with a constant temperature. The VWT circuit has an output with a temperature coefficient that is determined by the relative amount of current that flows through each current control element of the control circuit.