Abstract: Examples of password integrity scoring are described. In an example, an integrity score for a password may be determined based on a comparison of the password with a set of passwords for multiple users stored in a database. In some examples, the set of passwords may include in-use passwords and previously-used passwords for the multiple users. In some examples, the password may be stored into the database for scoring future passwords.

Abstract: Methods and compositions for treating retinoblastoma are disclosed. The methods comprise administering a composition comprising two or more chemotherapeutic agents and a fibrin sealant material to a patient in need thereof. The compositions comprise two or more chemotherapeutic agents and a fibrin sealant material. Also disclosed are dual-compartment syringes comprising two or more chemotherapeutic agents, fibrinogen, and thrombin.

Abstract: An application-centric modernization and migration (AMM) architecture delivers AMM as a service to enterprises to automate migrating applications to new environments. In this regard, the architecture implements data migration functionality in concert with application code migration, environment provisioning, and post-migration configuration. The joint migration of application data and application code effectively provides a complete migration of an application. The architecture may also define and deliver a GUI portal through which an application owner provides application-specific metadata to drive the AMM.

Abstract: In an illustrative embodiment, an aircraft galley ducting assembly provides airflow to at least one compartment of an aircraft galley monument. The ducting assembly may include a supply air duct that provides a supply airflow path to a compartment that includes an inlet port mounted to a compartment surface. A return air duct may provide an exit airflow path for return air that has circulated throughout the compartment and includes an outlet port mounted to the compartment surface. An airflow adjustment apparatus with an airflow adjustment surface is positioned within the supply airflow path of the supply air duct or the exit airflow path of the return air duct to cause a modification of airflow properties for air passing across or through the airflow adjustment surface.

Abstract: The inventions relates to compounds of (I) and therapeutic uses thereof: (I) The terms Z, Y, and R1 are as defined in the claims.

Abstract: Embodiments of the disclosure are drawn to apparatuses and methods for a rotating optical reflector. Optical systems may have a limited field of view, and so in order to expand the area that the optical system collects data from, the field of view of the optical system may be scanned across a target area. The present disclosure is directed to a rotating optical reflector, which includes a transmissive layer which refracts light onto a reflective layer, which has a normal which is not parallel to the axis about which the optical reflector is rotated. The optical reflector may be both statically and dynamically balanced, which may allow an increased size of the optical reflector, which in turn may increase the aperture of an optical system (e.g., a lidar system) using the rotating optical reflector.

Abstract: An exemplary paddle includes a central shaft having a first end and a second end. One or more lateral blades extend laterally from the central shaft, and each lateral blade including a geared end positioned adjacent the central shaft and a distal end opposite the geared end. Each lateral blade provides a blade gear at the geared end. A drive shaft is movably positioned within the central shaft and operatively coupled to the one or more lateral blades such that rotation of the drive shaft about a central axis rotates the one or more lateral blades about a corresponding one or more blade axes. The one or more lateral blades are able to move between a horizontal position and a vertical position via independent actuation.

Abstract: The inventions relates to compounds of (I) and therapeutic uses thereof: (I) The terms Z, Y, and R1 are as defined in the claims.

Abstract: Unicondylar tibia implant devices having a bone-facing, distal side that can be detailed with cement fixation features and may include any of or a plurality of grooves, pegs, fins, rails, cavities, and/or coating whereby the geometry of the implant device improves implant-to-cement or cement-to-bone fixation characteristics exceeding that of a traditional flat surface. The implant device may also include a proximal side facing away from the bone-facing, distal side and having a geometry that provides either articulation with (cartilage and meniscal substituting) or receipt of a secondary device coupleable to the implant device on the distal side of the secondary device that features an away-from-bone facing articulating feature. Additionally, the geometry of the implant device in anterior-posterior and medial-lateral directions, among other directions, provides a variety of improvements relative to currently available devices.

Abstract: Unicondylar tibia implant devices having a bone-facing, distal side that can be detailed with cement fixation features and may include any of or a plurality of grooves, pegs, fins, rails, cavities, and/or coating whereby the geometry of the implant device improves implant-to-cement or cement-to-bone fixation characteristics exceeding that of a traditional flat surface. The implant device may also include a proximal side facing away from the bone-facing, distal side and having a geometry that provides either articulation with (cartilage and meniscal substituting) or receipt of a secondary device coupleable to the implant device on the distal side of the secondary device that features an away-from-bone facing articulating feature. Additionally, the geometry of the implant device in anterior-posterior and medial-lateral directions, among other directions, provides a variety of improvements relative to currently available devices.

Abstract: In accordance with some embodiments of the present disclosure, a loading tool for a multi-well chromatography filter plate is disclosed. The loading tool may include a top plate and a bottom plate slidably coupled to the top plate. The top plate may include a plurality of wells for holding a material, a rail located along a side of the top plate, and a notch formed in the rail. The bottom plate may include a plurality of funnels extending from the bottom plate, each of the plurality of funnels corresponding to one of the plurality of wells, a track located along a side of the bottom plate to receive the rail located on the top plate, and a pathway formed in the track to receive the notch such that the notch and the pathway limit movement of the top plate relative to the bottom plate.

Abstract: An application-centric continuous delivery (ACCID) architecture provides a service that automates the configuration and management of end-to-end application lifecycle management (ALM) tools, through an innovative application-centric metadata model that can be customized through a self-service portal. With the ACCID architecture, IT organizations can provide version management, build automation, test automation, artifact management, infrastructure build, and automated application deployment that is consistent with global IT policy and governance and delivered as a service to organizations. The ACCID architecture references customized application metadata models that describe the application services, ALM requirements, and target infrastructure, to employ end-to-end automation of: the software deployment lifecycle and promotion across application environments, e.g., Development, Test, Pre-Production, and Production environments, using private, public, or hybrid cloud deployment models.

Abstract: A microwave heater and a method of heating are provided. The microwave heater includes a non-modal interplate microwave applicator and may include a nonresonant enclosure. The non-modal interplate microwave applicator is configured to receive therein a load to be heated by microwaves radiated from the non-modal interplate microwave applicator.

Abstract: Unicondylar tibia implant devices having a bone-facing, distal side that can be detailed with cement fixation features and may include any of or a plurality of grooves, pegs, fins, rails, cavities, and/or coating whereby the geometry of the implant device improves implant-to-cement or cement-to-bone fixation characteristics exceeding that of a traditional flat surface. The implant device may also include a proximal side facing away from the bone-facing, distal side and having a geometry that provides either articulation with (cartilage and meniscal substituting) or receipt of a secondary device coupleable to the implant device on the distal side of the secondary device that features an away-from-bone facing articulating feature. Additionally, the geometry of the implant device in anterior-posterior and medial-lateral directions, among other directions, provides a variety of improvements relative to currently available devices.

Abstract: Methods and systems for managing pricing guarantees for prescription drugs are described. In one embodiment, a designation of a pharmacy within a pharmacy network may be received as a preferred pharmacy designation. The preferred pharmacy designation may be associated with a member. A set of preferred pharmacy benefits may be associated with the member and the preferred pharmacy designation. A pharmacy claim associated with the preferred pharmacy designation for a prescription for the member may be adjudicated based on the set of preferred pharmacy benefits. Other methods and systems are described.

Abstract: Techniques disclosed herein provide a geolocation-based two-factor authentication process. An authentication service receives a first authentication factor associated with an account. Upon validating the first authentication factor, the authentication service requests a second authentication factor from an application executing on a mobile device associated with the account. The second authentication factor identifies at least a location of the mobile device. The authentication service determines a location of the client device. Upon determining that the locations of the mobile device and of the client device are within a specified proximity of one another, the authentication service grants access to the account.

Abstract: The inventions relates to compounds of (I) and therapeutic uses thereof: (I) The terms Z, Y, and R1 are as defined in the claims.

Abstract: A monitoring system for monitoring an offshore construction is presented. The offshore construction to be monitored comprises mutually mechanically coupled marine assets. The monitoring system comprises a data storage unit, an intrusion detection service, an input device, and an update service. The data storage unit stores data specifying a spatial range of at least one warning zone pertaining to the offshore construction. The intrusion detection service is provided to detecting an intrusion of the spatial range and for issuing an alert message upon such detection. The input device receives position information for one or more of the marine assets. The update service updates the spatial range of the at least one warning zone based on the received position information. Additionally a monitoring method and a computer program product are provided.

Abstract: The inventions relates to compounds of (I) and therapeutic uses thereof: (I) The terms Z, Y, and R1 are as defined in the claims.

Abstract: An application-centric modernization and migration (AMM) architecture delivers AMM as a service to enterprises to automate migrating applications to new environments. In this regard, the architecture implements data migration functionality in concert with application code migration, environment provisioning, and post-migration configuration. The joint migration of application data and application code effectively provides a complete migration of an application. The architecture may also define and deliver a GUI portal through which an application owner provides application-specific metadata to drive the AMM.