Abstract: Methods and compositions are provided for reducing intraocular pressure, for example in the treatment of glaucoma or ocular hypertension. The method includes introducing into a suprachoroidal space of an eye of the patient a composition effective to maintain a reduction in IOP for at least 30 days. The composition may include a cross-linked hydrogel or a material configured to crosslink or further crosslink in vivo.

Abstract: Three-dimensional solar power generation systems have a plurality of solar panels configured to include pole and equator facing panels and, in various embodiments additional top and/or side panels that form a segmented and dome-shaped assembly. The systems have improved efficiencies particularly with respect to early morning and evening power generation that enable improved power densities on a given land area as compared to traditional solar panel arrays. Methods of deploying the systems are also described.

Abstract: A system for cutting medical tubing sourced from a spool of tubing uses two actuator groups that each reciprocate along a respective track, which are parallel to each other. Each actuator group has a clamp and a cutting tool which have an operative position along a common axis. The tubing is fed along the common axis to be operated on by the actuator groups. A forward actuator group clamps onto the tubing and is then moved along its track, pulling the tubing. A rearward actuator group then clamps onto the tubing and cuts the tubing. While still clamped onto the tubing, the rearward actuator group is moved forward, pulling more tubing, and the actuator group that was forward is moved to the rearward position and the process is repeated iteratively to produce tubing sections cut to the desired length. The tubing is pressurized and kept under pressure to straighten the tubing.

Abstract: Described herein are methods of for treating and/or preventing Major adverse cardiovascular events (MACE). by administering to a subject in need thereof, a combination of a sodium-glucose transport protein 2 (SGLT2) inhibitor and a compound of Formula I or a stereoisomer, tautomer, pharmaceutically acceptable salt, or hydrate thereof, wherein the variables of Formula I are as defined herein.

Abstract: A fishing line spooling station comprises a spool support having a first side and a second side and a side support extending perpendicularly from the first side of the spool support. The spool support includes an opening with side rails and a threaded central shaft. A brake slider having a brake face oriented toward the side support engages the rails and the central shaft and is positioned relative to the side support with a brake slide adjustment thumbscrew. The side support includes a height adjustment slot and a spool spindle extends perpendicularly from the side support.

Abstract: Three-dimensional solar power generation systems are described. The systems are characterized by a plurality of solar panels configured to include pole and equator facing panels and, in various embodiments additional top and/or side panels that form a segmented and dome-shaped assembly. The systems have improved efficiencies particularly with respect to early morning and evening power generation that enable improved power densities on a given land area as compared to traditional solar panel arrays. Methods of deploying the systems are also described.

Abstract: A positionable connector assembly comprises a base, a connector operatively connected to the base, a friction member positioned between the base and the connector, and a biasing member operatively connected to the connector and configured and arranged to bias the connector toward the friction member.

Abstract: A fraud detection system is disclosed that detects potential fraudulent behavior associated a user account by identifying attributes of the user account that share attributes with one or more known fraudulent user accounts. The set of shared attributes for a user account are identified by constructing a bipartite graph comprising a set of user account nodes and a set of attribute nodes associated with the set of user account nodes. A match score for the user account is computed based on the set of shared attributes. Actions to be taken for the user account are identified based on the match score. The actions may include tagging the user account as potentially fraudulent. The actions can be used by a user (e.g., an administrator) of an organization to more intelligently determine appropriate measures to be taken for the potentially fraudulent user account.

Abstract: A system for cutting medical tubing sourced from a spool of tubing uses two actuator groups that each reciprocate along a respective track, which are parallel to each other. Each actuator group has a clamp and a cutting tool which have an operative position along a common axis. The tubing is fed along the common axis to be operated on by the actuator groups. A forward actuator group clamps onto the tubing and is then moved along its track, pulling the tubing. A rearward actuator group then clamps onto the tubing and cuts the tubing. While still clamped onto the tubing, the rearward actuator group is moved forward, pulling more tubing, and the actuator group that was forward is moved to the rearward position and the process is repeated iteratively to produce tubing sections cut to the desired length. The tubing is pressurized and kept under pressure to straighten the tubing.

Abstract: A method and apparatus for a commerce platform coordinating a purchase of a product sold by a merchant system through a third party application are described. The method may include receiving a notification from the third party application requesting to purchase a product from within the third party application, wherein the notification comprises an identifier for the product and an identifier for the merchant system that sells the product. The method may also include a product checkout interface having an appearance consistent with an appearance of a user interface of the third party application, and transmitting the product checkout interface generated by the commerce platform to a user device executing the third party application causing the third party application to render the product checkout interface within at least a portion of the user interface of the third party application.

Abstract: A system enables digital appliances to be monitored by a device monitoring application. The system includes a plurality of digital appliances, a device monitoring application service configured to communicate with the plurality of digital appliances, and a device regulation/support site. The device regulation/support site is configured to provision the digital appliances for communication with the device monitoring application in response to an authentication token received from one of the digital appliances through the device monitoring application service corresponding to an authentication token stored in a database at the device regulation/support site.

Abstract: Systems and methods are described that include generating a virtual reality experience in a virtual reality environment, detecting, a first gesture from a first user accessing the virtual reality environment, the first gesture being configured as a command to initiate a privacy mode with a second user accessing the virtual reality environment, and generating a prompt for display to the second user, the prompt corresponding to the command. In response to detecting a second gesture from the second user, the second gesture determined to substantially match the first gesture, initiating the privacy mode between the first user and the second user in the virtual reality environment, and sharing communications occurring in the virtual environment from the first user to the second user and from the second user to the first user while modifying, for users other than the first user and the second user, the communications occurring between the first user and the second user.

Abstract: A system enables digital appliances to couple to third party application services directly. The system includes a device regulation/support site configured to generate a script program and a data template, and a digital appliance that selectively couples to the device regulation/support site and receives the script program and data template from the device regulation/support site, the digital appliance executes the script program with reference to the data template to couple directly to a third party application service and query the third party application service for data.

Abstract: A therapeutic pelvic region analyzer and method of use thereof that includes an expandable device sized and shaped for insertion into an opening in a pelvic region of a user and a collapsible reservoir fluidly coupled to the expandable device. The collapsible reservoir is configured to temporarily retain and expel an amount of fluid. A tube defining a fluid-flow path for the amount of fluid is between the expandable device and the collapsible reservoir. The therapeutic pelvic region analyzer also includes fluid-flow control valve disposed between the expandable device and the collapsible reservoir. The fluid-flow control valve is operable to provide a selectively variable level of resistance as the amount fluid passes from the expandable device to the collapsible reservoir.

Abstract: Systems and methods for a volumetric multi-selection interface for selecting multiple entities in three-dimensional (3D) space are provided. An example method includes generating a selection region within a three-dimensional space and receiving a selection path user input to define a selection path. The method also includes defining a selection volume based on the selection region and the selection path and selecting entities within the 3D space based on the selection volume. In some implementations, an alter selection region user input is received while the selection path is being defined. The size or shape of the selection region may be altered in response thereto.

Abstract: A method for processing healthcare information includes: receiving information related to a patient and a plurality of providers involved with caring for the patient; using the information to generate patient centered provider graphs that describe relationships among the patient and the plurality of providers and include an indication of provider availability within a clinical situation; and presenting the graphs to a plurality of uses. An apparatus that is used to practice the method is also provided.

Abstract: An extender for holding boating accessories including at least a first limb and a second limb engaged in elbow relationship such that one can be pivoted with respect to the other about a transverse axis. At least one of the limbs includes a swivel portion that is able to turn about a longitudinal axis. At least one locking part moves longitudinally along a respective one of the limbs between locked and unlocked positions. When the locking part is in the locked position, it prevents the swivel portion turning.

Abstract: According to an example implementation, a method may include receiving, from a non-virtual reality application, a non-virtual reality event notification, and providing, in a virtual environment based on the non-virtual reality event notification, a non-textual indication of a status of the non-virtual reality application, wherein a characteristic of the non-textual indication is adjusted to indicate the status of the non-virtual reality application.