Patents by Inventor Christopher Thanos

Christopher Thanos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090291890
    Abstract: Modified factor VII polypeptides and uses thereof are provided. Such modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.
    Type: Application
    Filed: April 10, 2009
    Publication date: November 26, 2009
    Inventors: Edwin L. Madison, Christopher Thanos
  • Publication number: 20090098103
    Abstract: Modified factor VII polypeptides and uses thereof are provided. Such modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.
    Type: Application
    Filed: April 11, 2008
    Publication date: April 16, 2009
    Inventors: Edwin L. Madison, Christopher Thanos, Sandra Waugh Ruggles, Shaun Coughlin
  • Publication number: 20090075375
    Abstract: The present invention is directed to the use of choroids plexus cells and/or choroids plexus conditioned media for enhancing the growth, survival and/or maintenance of function of non-choroid plexus cells grown in long term or short term culture.
    Type: Application
    Filed: September 15, 2008
    Publication date: March 19, 2009
    Applicant: Neurotrophincell Pty Limited
    Inventors: Robert Bartlett Elliott, Stephen John Martin Skinner, Livia Del Carmen Escobar Orellana, Christopher Thanos, Thorsten Gorba
  • Publication number: 20080286864
    Abstract: The present invention is directed to the use of choroid plexus cells and/or choroid plexus conditioned media for enhancing the growth, survival and/or maintenance of function of non-choroid plexus cells grown in long term or short term culture.
    Type: Application
    Filed: April 18, 2006
    Publication date: November 20, 2008
    Applicant: Neurotrophincell Pty Limited
    Inventors: Robert Bartlett Elliott, Stephen John Martin Skinner, Livia Del Carmen Escobar Orellana, Christopher Thanos
  • Publication number: 20080119909
    Abstract: The present invention is directed to the prevention or treatment of sensorineural hearing loss by administering a therapeutically effective amount of an implantable composition comprising encapsulated living choroid plexus cells.
    Type: Application
    Filed: March 6, 2007
    Publication date: May 22, 2008
    Applicants: NEUROTROPHINCELL PTY LIMITED, LIVING CELL TECHNOLOGIES PTY LIMITED
    Inventors: Stephen John Martin Skinner, Marilyn Sandra Geaney, Paul Lip Jin Tan, Robert Keith Shepherd, Lisa Narelle Pettingill, Jacqueline Kate Andrew, Christopher Thanos, Dwaine Emerich
  • Publication number: 20070093443
    Abstract: Provided are methods for and compounds for modulating the complement system. In particular, compounds are provided that inhibit complement activation and compounds are provided that promote complement activation. The compounds are therapeutics by virtue of their effects on the complement system. Hence, the compounds that inhibit complement activation can be used for treatment of ischemic and reperfusion disorders, including myocardial infarction and stroke, sepsis, autoimmune diseases, inflammatory diseases and diseases with an inflammatory component, including Alzheimer's Disease and other neurodegenerative disorder.
    Type: Application
    Filed: October 20, 2006
    Publication date: April 26, 2007
    Inventors: Edwin Madison, Jack Nguyen, Sandra Ruggles, Christopher Thanos
  • Publication number: 20060029590
    Abstract: Administration of recombinant, truncated mammalian NEP or certain bacterial homologues of this protein is therapeutically effective in the treatment of inflammatory bowel disease.
    Type: Application
    Filed: June 10, 2005
    Publication date: February 9, 2006
    Inventors: Christopher Thanos, Edwin Madison
  • Publication number: 20050100595
    Abstract: The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.
    Type: Application
    Filed: November 30, 2004
    Publication date: May 12, 2005
    Applicant: Brown University Research Foundation
    Inventors: Edith Mathiowitz, Christopher Thanos, Zhi Liu
  • Patent number: 6824791
    Abstract: The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.
    Type: Grant
    Filed: January 16, 2004
    Date of Patent: November 30, 2004
    Assignee: Brown University Research Foundation
    Inventors: Edith Mathiowitz, Christopher Thanos, Zhi Liu
  • Publication number: 20040166168
    Abstract: The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.
    Type: Application
    Filed: January 16, 2004
    Publication date: August 26, 2004
    Applicant: Brown University Research Foundation
    Inventors: Edith Mathiowitz, Christopher Thanos, Zhi Liu
  • Patent number: 6746635
    Abstract: The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.
    Type: Grant
    Filed: August 8, 2002
    Date of Patent: June 8, 2004
    Assignee: Brown University Research Foundation
    Inventors: Edith Mathiowitz, Christopher Thanos, Zhi Liu
  • Publication number: 20030108669
    Abstract: The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.
    Type: Application
    Filed: August 8, 2002
    Publication date: June 12, 2003
    Inventors: Edith Mathiowitz, Christopher Thanos, Zhi Liu