Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g.

Abstract: A display device and a method of manufacturing a display device are provided. An embodiment of a display device includes a substrate; a first conductive layer disposed on the substrate; a first insulating layer disposed on the first conductive layer; a second conductive layer connected to the first conductive layer through a first contact hole in the first insulating layer; a second insulating layer filling an inside of the first contact hole; and a third insulating layer disposed on the second conductive layer and the second insulating layer. The first insulating layer includes a first region that overlaps the second conductive layer and a second region that does not overlap the second conductive layer, and a top surface of the first region of the first insulating layer is positioned higher than a top surface of the second region of the first insulating layer.

Abstract: A paste for a reference electrode according to an embodiment of the present disclosure includes silver chloride powder and a carbon-based conductive material. The carbon-based conductive material may include at least one compound selected from the group consisting of carbon nanotubes, graphite, graphene, and carbon black. The reference electrode formed of the paste for a reference electrode according to an exemplary embodiment may provide improved mechanical properties and electrochemical properties.

Abstract: A switching fabric role assignment system includes a plurality of switch devices coupled together in a switching fabric. A first switch device included in the plurality of switch devices receives an endhost device identification communication from an endhost device when the endhost device is connected to the first switch device. The first switch device uses the endhost device identification communication to identify an endhost device type of the endhost device and determines, based on the endhost device type, a first switch device role for the first switch device. The first switch device then transmits a first switch device role communication that identifies the first switch device role to a second switch device included in the plurality of switch devices and connected to the first switch device. The second switch device may then determine, based on the first switch device role, a second switch device role for the second switch device.

Abstract: A paste for a reference electrode according to an embodiment of the present disclosure includes silver chloride powder and a carbon-based conductive material. The carbon-based conductive material may include at least one compound selected from the group consisting of carbon nanotubes, graphite, graphene, and carbon black. The reference electrode formed of the paste for a reference electrode according to an exemplary embodiment may provide improved mechanical properties and electrochemical properties.

Abstract: A switching fabric role assignment system includes a plurality of switch devices coupled together in a switching fabric. A first switch device included in the plurality of switch devices receives an endhost device identification communication from an endhost device when the endhost device is connected to the first switch device. The first switch device uses the endhost device identification communication to identify an endhost device type of the endhost device and determines, based on the endhost device type, a first switch device role for the first switch device. The first switch device then transmits a first switch device role communication that identifies the first switch device role to a second switch device included in the plurality of switch devices and connected to the first switch device. The second switch device may then determine, based on the first switch device role, a second switch device role for the second switch device.

Abstract: A switching fabric role assignment system includes a plurality of switch devices coupled together in a switching fabric. A first switch device included in the plurality of switch devices receives an endhost device identification communication from an endhost device when the endhost device is connected to the first switch device. The first switch device uses the endhost device identification communication to identify an endhost device type of the endhost device and determines, based on the endhost device type, a first switch device role for the first switch device. The first switch device then transmits a first switch device role communication that identifies the first switch device role to a second switch device included in the plurality of switch devices and connected to the first switch device. The second switch device may then determine, based on the first switch device role, a second switch device role for the second switch device.

Abstract: A method of a responding entity for creating a secure link with a requesting entity in an embedded universal integrated circuit card (eUICC) environment is provided. The method includes: receiving, from the requesting entity, a secure link creation message including signature information of the requesting entity; verifying the signature information of the requesting entity by using trust information of the requesting entity, the trust information of the requesting entity being generated by a certificate authority (CA) and transferred to the responding entity; generating a shared key used for communication between the responding entity and the requesting entity; and creating the secure link with the requesting entity by using the shared key.

Abstract: A switching fabric loop prevention system includes first slave switch devices in a switching fabric that each automatically determine a first slave switch device role for themselves based on first directly connected device identification information received from a first directly connected device, and second slave switch devices in the switching fabric that each automatically determine a second slave switch device role for themselves based on second directly connected device identification information received from a second directly connected device. A master switch device in the switching fabric then configures each of the first slave switch devices having the first slave switch device role to prevent first type communications that have been received from one of the second slave switch devices having the second slave switch device role from being forwarded to another of the second slave switch devices having the second slave switch device role.

Abstract: A switching fabric role assignment system includes a plurality of switch devices coupled together in a switching fabric. A first switch device included in the plurality of switch devices receives an endhost device identification communication from an endhost device when the endhost device is connected to the first switch device. The first switch device uses the endhost device identification communication to identify an endhost device type of the endhost device and determines, based on the endhost device type, a first switch device role for the first switch device. The first switch device then transmits a first switch device role communication that identifies the first switch device role to a second switch device included in the plurality of switch devices and connected to the first switch device. The second switch device may then determine, based on the first switch device role, a second switch device role for the second switch device.

Abstract: A switching fabric configuration and management system includes switch devices. Each of the switch devices identifies a domain in a switching fabric database in that switch device, and determines others of the switch devices that share the domain. Each of the switch devices may then communicate with the others of the switch devices that share the domain to designate a master switch device and one or more slave switch devices from the switch devices that share the domain. The designation of the master switch device and the one or more slave switch devices configures the master switch device and the one or more slave switch devices as a switching fabric. Each slave switch devices then reports their slave switch device status to the master switch device, and the master switch device performs at least one control operation on the at least one slave switch device.

Abstract: A switching fabric loop prevention system includes first slave switch devices in a switching fabric that each automatically determine a first slave switch device role for themselves based on first directly connected device identification information received from a first directly connected device, and second slave switch devices in the switching fabric that each automatically determine a second slave switch device role for themselves based on second directly connected device identification information received from a second directly connected device. A master switch device in the switching fabric then configures each of the first slave switch devices having the first slave switch device role to prevent first type communications that have been received from one of the second slave switch devices having the second slave switch device role from being forwarded to another of the second slave switch devices having the second slave switch device role.

Abstract: A method and device for managing an identifier of an embedded universal integrated circuit card (eUICC) is disclosed. The eUICC receives an identifier information request, determines whether there is a network carrier profile in an enabled state, and provides a response with identifier information corresponding to the identifier information request based on the results of the determination. According to the method, it is possible to separately manage the unique identifier of the eUICC and a network carrier ICCID and to dynamically manage the identifier of the eUICC according to the state of the network carrier profile of the eUICC.

Abstract: A method for providing mobile communication provider information and a device for performing the same are disclosed. A terminal having an eUICC receives data, in which mobile communication provider information is capsulized and included, and stores the received data in the eUICC. Therefore, the mobile communication provider information can be transferred by applying the highest security scheme, and duplication of the eUICC due to the exposure of an authentication key by external hacking attacks can be prevented.

Abstract: A method for configuring a profile of a subscriber authenticating module embedded and installed in a terminal device, and an apparatus using same, are disclosed. The subscriber authenticating module embedded and installed in the terminal device according to an exemplary embodiment includes one or more network access application related data sets and one or more profiles having unique identifiers. The present invention enables an eco-system provider such as a network service provider, a eUICC manufacturer, or a terminal manufacturer to develop an efficient and rapid eUICC and provide a eUICC service.

Abstract: Provided are a method and device for building a security-based environment that uses an eUICC. A method of building a trust relationship in an eUICC environment includes transmitting, by a trust requesting object, a trust relationship requesting message including identification information and signature information of the trust requesting object to a trust verifying object, delivering, by the trust verifying object, the trust relationship requesting message to a trust relationship relay object and receiving trust information of the trust requesting object corresponding to the trust relationship requesting message from the trust relationship relay object, and verifying, by the trust verifying object, the signature information of the trust requesting object using the trust information of the trust requesting object.

Abstract: A terminal device having a subscriber identity device and a method for selecting a profile thereof, are disclosed. A mobile communication terminal device comprises: a subscriber identity module including a profile, a network authenticator which performs an authentication procedure for a communication network on the basis of a provisioning profile among profiles, and which receives authentication completion information from an operator server of the communication network; and a network access unit which accesses the communication network on the basis of the authentication completion information, and which receives a service from the operator server on the basis of an operational profile corresponding to an operator of the communication network among the profiles.

Abstract: Disclosed is an artificial valved conduit that is a composite valved graft comprising double sewing cuffs, which can be easily used in aortic root replacement. The composite valved graft comprises a valve and a conduit part connected to the valve. The conduit part comprises a sewing cuff positioned on the outer circumference thereof. The sewing cuff comprises a first sewing cuff and a second sewing cuff positioned below the first sewing cuff. Accordingly, a double suture is easily performed, so that it is possible to prevent the loss of blood after a surgery and to reduce surgical time at the same time.

Abstract: A terminal device having a subscriber identity device and a method for selecting a profile thereof, are disclosed. A mobile communication terminal device comprises: a subscriber identity module including a profile, a network authenticator which performs an authentication procedure for a communication network on the basis of a provisioning profile among profiles, and which receives authentication completion information from an operator server of the communication network; and a network access unit which accesses the communication network on the basis of the authentication completion information, and which receives a service from the operator server on the basis of an operational profile corresponding to an operator of the communication network among the profiles.

Abstract: Provided is a method of monitoring a blind spot of stationary monitoring devices in a target monitoring area using at least one moving object. The method may include detecting at least one moving object located near to a blind spot of stationary monitoring devices in a target monitoring area upon generation of a predetermined initiation event, and monitoring the blind spot of the stationary monitoring devices using a monitoring device mounted on the detected at least one moving object.