Abstract: A hinge mechanism being used for a foldable electronic device is provided. The foldable electronic device comprises a first panel body and a second panel body, which are pivotable with respect to each other The hinge mechanism comprises a central plate, a first pivoting element and a second pivoting element. The central plate comprises a first curved section and a second curved section. The first pivoting element is fixed to the first panel body and grips the first curved section. The second pivoting element is fixed to the second panel body and grips the second curved section. When the first pivoting element and the second pivoting element switch between a retracted position and a stretched position, the first panel body and the second panel body change between an unfolded status and a folded status correspondingly.

Abstract: A supporting stand is provided. The supporting stand includes an upright, a slidable clipping unit, a slider, an elastic element, and a bearing board. The upright includes a column body. The slidable clipping unit clamps the column body, and includes a structural sleeve element and a contact element. The contact element has a first contact body and a second contact body being rollable relative to the column body. The elastic element is connected to the column body and the structural sleeve element. The slider is configured to the structural sleeve element. The bearing board is disposed on the slider and bears the display. When an external force is applied, the structural sleeve element makes the slider move between a highest position and a lowest position, and when the external force is removed, the slider stops at any position between the highest position and the lowest position.

Abstract: The present disclosure provides methods for testing whether a target protein regulates viral RNA translation. The methods comprise a) introducing into a test host cell (where the test host cell comprises a catalytically inactive or a catalytically active CRISPR/Cas effector polypeptide): i) a reporter nucleic acid comprising a nucleotide sequence encoding a bicistronic translation monitor; and ii) a regulatory nucleic acid comprising a nucleotide sequence encoding a single guide RNA (sgRNA) that comprises a targeting sequence that specifically binds to a target sequence within a nucleic acid encoding the target protein; and b) detecting expression of the reporter proteins to determine whether a target protein regulates viral RNA translation via a Cap-dependent element or a Cap-independent element based on the expression of the reporter proteins in the test host cell as compared to the expression in the control host cell. Kits for conducting the methods disclosed herein are also provided.

Abstract: The present disclosure provides CDK9 inhibitors. Also provided are methods of treating a disease or a disorder comprising administering to a subject in need of treatment one of the CDK9 inhibitors disclosed herein. In some embodiments, the disease or disorder to be treated is cancer. In some embodiments, the disease or disorder is liver cancer.

Abstract: In one aspect, the present disclosure provides a method for identifying treatment targets relating to tumors. In another aspect, the present disclosure provides a method for identifying biomarkers and molecular features of normal and cancer cells.

Abstract: A touch electronic paper display device includes an electronic paper display module, a lighting module, a touch sensing unit and a cover plate. The lighting module is disposed on the electronic paper display module and adhered to the electronic paper display module with a UV-curing solid optical clear adhesive. The lighting module includes a light strip and a light guide plate whose one side is adjacent to the light strip. The touch sensing unit is located on the lighting module. The cover plate is located on the touch sensing unit. A top surface of the cover plate is disposed with a UV-reflecting coating, and a periphery of a bottom surface thereof is disposed with a decorative bezel formed by an opaque or low light transmittance material.

Abstract: An image processing method applied to a display device having a processing circuit and a screen and includes: receiving a first image from one of a plurality of electronic devices; detecting whether the first image has a black border area; and if the first image has the black border area, performing a first display operation, wherein performing the first display operation includes: removing the black border area of the first image, to generate a second image; adjusting the size of the second image according to the size of a display area of the screen; calculating a first blank area of the screen based on the adjusted second image; requesting a third image from another one of the electronic devices according to the size of the first blank area; and filling the display area of the screen with the adjusted second image and the third image.

Abstract: A hinge includes a bearing plate, a linkage mechanism, a shell element, and an elastic element. The linkage mechanism is linked to the bearing plate. The shell element is disposed on the support, is connected to the linkage mechanism and includes a receiving space. The elastic element is disposed in the receiving space and abuts against between the linkage mechanism and the shell element to provide an elastic force. When an external force is applied, the display device and the bearing plate rotate relative to the support between a first position and a second position. The bearing plate is linked to the linkage mechanism to compress or loosen the elastic element, and then the elastic force is changed. When the external force is removed, the display device and the bearing plate can be stopped at once at any position between the first position and the second position.

Abstract: A foldable electronic device is provided. The foldable electronic device includes a central body, a linkage unit, a plurality of operating mechanisms, and a plurality of panel bodies. The linkage unit includes a plurality of driving shafts. Each of the operating mechanism has a wing rod, a lifting plate, and a connecting rod. The wing rod is fixed to the lifting plate. The wing rod and the connecting rod pivotally connecting to the central body and the driving shaft respectively. When the panel bodies are in a folded status, a flexible screen is bent, and the wing rod, the lifting plate, and the central body collectively define a yielding space for accommodating a flexible section of the flexible section.

Abstract: A display panel control chip including a processor and a signal processing circuit is provided. The processor controls a display panel to display first and second images corresponding to first and second video signals. The first image is adjacent to the second image by a border extending in perpendicular to a first direction at a first coordinate. The signal processing circuit stores the first coordinate, determines whether a first cursor is in the first image or the second image according to a cursor control signal and the first coordinate, and transmits, according to the determination, the cursor control signal to either a signal source of the first video signal or a signal source of the second video signal. When an area ratio of the first image to the second image is changed, the processor controls the signal processing circuit to update the first coordinate.

Abstract: A golf club head includes a main body and a plate member disposed on the main body. The plate member includes a plurality of carbon fiber layers which are stacked on each other and are impregnated with a thermoset carbon fiber resin containing carbon nanotubes. The carbon nanotubes are present in an amount ranging from 0.01 wt% to 5 wt%, based on the total weight of the thermoset carbon fiber resin.

Abstract: A supporting device is provided and includes: a base; an upright column disposed on the base; a lifting module disposed on the upright column; a constant force arm unit including: a first rotating member rotatably disposed on the upright column and defining a constant first effective force arm; and a first wire wound on the first rotating member; a variable force arm unit including: a second rotating member linked with the first rotating member and defining a variable second effective force arm; and a second wire wound on the second rotating member; and an elastic force module connected to the first wire; where the torques respectively generated in the first wire and the second wire are balanced with each other.

Abstract: An elevatable supporting device for bearing a display is provided. The elevatable supporting device comprises an upright, an energy storage element, and a bearing module. The upright includes a first surface and a second surface which is non-parallel to the first surface. The energy storage element abuts against the first surface and the second surface and includes a first arm providing a first resistance and a second arm providing a second resistance. A first included angle is defined between the first arm and the second arm. When the energy storage element moves from the highest position to the lowest position, the first included angle decreases so that one of the first resistance and the second resistance may increase in order to maintain a total effective resistance along the first axis. Accordingly, the display may be able to stop at any position between the highest position and the lowest position.

Abstract: A scaler integrated circuit (IC) applicable to performing multi-picture processing in a display device includes multiple terminals, multiple Extended Display Identification Data (EDID) circuits and a control circuit. The control circuit receives a Multi-Stream Transport (MST) video stream from a video source through a first video input terminal, analyzes the MST video stream to generate a first Single Stream Transport (SST) video stream and a second SST video stream, sends the second SST video stream through a video output terminal to be a video output signal, and receives the video output signal through a second video input terminal, to allow the scaler IC to generate a combination picture according to the first SST video stream and the second SST video stream, for being displayed by a display output module within the display device.

Abstract: A portable electronic device is provided. The portable electronic device comprises a main body, a flexible display, two pivoting modules and a central shaft. The flexible display is pivotably disposed on the main body. The pivoting modules are connected between the flexible display and the main body for pivotally connecting the flexible display to the main body. The central shaft penetrates through the pivoting modules along an axis. The flexible display gradually bends inward to form a curved surface along with the flexible display pivoting from a close status to an open status with respect to the main body about the axis.

Abstract: A control device includes a signal-output device, a signal modulation device, a storage device, and a processing device. The signal-output device outputs a plurality of data signals. The signal modulation device outputs a plurality of modulation signals. The storage device is coupled to the signal-output device and stores a large amount of display data. The processing device is coupled to the signal-output device and the signal modulation device. The processing device controls the signal-output device so that the signal-output device divides the display data and transforms the display data into the data signals according to the repeat performing number and the moving position region, so as to sequentially output the data signals. The processing device controls the signal modulation device, so that the signal modulation device sequentially outputs the modulation signals according to the pulse wave counting number and the pixel unit number.

Abstract: The present disclosure provides CDK9 inhibitors. Also provided are methods of treating a disease or a disorder comprising administering to a subject in need of treatment one of the CDK9 inhibitors disclosed herein. In some embodiments, the disease or disorder to be treated is cancer. In some embodiments, the disease or disorder is liver cancer.

Abstract: A golf club head includes a club head main body and a crown. The club head main body includes a main portion, and a receiving portion connected to the main portion. The main portion has an outer shell surface, and an upright side wall surface interconnecting the outer shell surface and the receiving portion. The crown includes a covering portion, and a protrusion protruding upwardly from an outer periphery of the covering portion, adjoining the side wall surface, and having a to-be-ground surface flushing with the outer shell surface. A height difference between the protrusion and the covering portion prevents the covering portion from being ground.

Abstract: An elevatable supporting device for bearing a display is provided. The elevatable supporting device comprises an upright, an energy storage element, and a bearing module. The upright includes a first surface and a second surface which is non-parallel to the first surface. The energy storage element abuts against the first surface and the second surface and includes a first arm providing a first resistance and a second arm providing a second resistance. A first included angle is defined between the first arm and the second arm. When the energy storage element moves from the highest position to the lowest position, the first included angle decreases so that one of the first resistance and the second resistance may increase in order to maintain a total effective resistance along the first axis. Accordingly, the display may be able to stop at any position between the highest position and the lowest position.

Abstract: The present disclosure provides methods and systems for identification of genomic regions for therapeutic targeting. A method for identifying one or more genomic regions for therapeutic targeting, which may facilitate re-programming of a cell from one phenotypic state to another, may comprise: providing single-cell RNA-seq data for a plurality of diseased cells and a plurality of normal cells of a cell type; mapping the single-cell RNA-seq data for the plurality of diseased cells and the plurality of normal cells into a latent space corresponding to a plurality of phenotypic states of the cell type; identifying, based at least in part on a topology of the latent space, the one or more genomic regions for therapeutic targeting; and electronically outputting the one or more genomic regions for therapeutic targeting.