Abstract: Processes to make intermediates to produce mesoionic pesticides are disclosed. Processes to produce N-(pyrimidin-5-ylmethyl)pyridin-2-amine, an important intermediate, are disclosed.

Abstract: Methods for preparing 5-fluoro-6-(bromo or chloro)picloram analogs, or derivatives thereof, from picloram acid, picloram ester, or the nitrile analog of picloram are provided. The methods include chemical process steps that: (1) introduce a phthaloyl group onto the 4-amino substituent of picloram acid, picloram ester, or the nitrile analog of picloram, (2) add 2 fluorine atoms at the 5,6-positions of the pyridine ring using halex fluorination chemistry, (3) remove the phthaloyl group, hydrolyze the ester or nitrile substituent, and add chlorine or bromine to the 6-position by treatment with an acid and water, and finally, (4) esterify the 5-fluoro-6-(bromo or chloro)picloram acid produced in step (3) to a 5-fluoro-6-(bromo or chloro)picloram ester.

Abstract: Addition curing electrically conductive liquid silicone rubber (LSR) compositions, their methods of preparation, and cured elastomeric products made from the compositions are provided. The compositions are cured to form elastomeric products suitable for high voltage applications such as cable joints, cable terminal applications, cable accessories and connectors. In general, the composition comprises: (a) at least one polydiorganosiloxane having at least two alkenyl groups per molecule: (b) at least one organohydrogenpolysiloxane: (c) at least one reinforcing filler: (d) at least one hydrosilylation catalyst: and (e) an electrically conductive filler. Component (e) comprises: (i) extra conductive carbon black: and (ii) single walled carbon nanotubes.

Abstract: The present disclosure relates to improved processes for preparing 4-amino-6-(heterocyclic)picolinates.

Abstract: The present disclosure relates to improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates.

Abstract: Methods for preparing 5-fluoro-6-(bromo or chloro)picloram analogs, or derivatives thereof, from picloram acid, picloram ester, or the nitrile analog of picloram are provided. The methods include chemical process steps that: (1) introduce a phthaloyl group onto the 4-amino substituent of picloram acid, picloram ester, or the nitrile analog of picloram, (2) add 2 fluorine atoms at the 5,6-positions of the pyridine ring using halex fluorination chemistry, (3) remove the phthaloyl group, hydrolyze the ester or nitrile substituent, and add chlorine or bromine to the 6-position by treatment with an acid and water, and finally, (4) esterify the 5-fluoro-6-(bromo or chloro)picloram acid produced in step (3) to a 5-fluoro-6-(bromo or chloro)picloram ester.

Abstract: A method for obtaining an intracellular deterministic event, and an electronic device. The method includes: an electronic device obtaining several pieces of mutant gene information of a tested sample extracted from a target object; and the electronic device obtaining, according to the several pieces of mutant gene information, comprehensive influence parameter data of several mutant genes regarding the expression activity of each gene in a predetermined genome.

Abstract: A disease type automatic determination method and an electronic device, wherein the method includes: the electronic device obtains comprehensive influence parameter data of several mutant genes of a tested sample on expression activity of each gene in a predetermined genome (S81); and the electronic device determines a disease type label corresponding to the tested sample on the basis of the comprehensive influence parameter data of the several mutant genes of the tested sample on expression activity of each gene in the predetermined genome.

Abstract: The present application disclosed a method for automatically predicting treatment management factor characteristics and an electronic apparatus, the method includes: acquiring, by the electronic apparatus, concerted effect burden parameter data of several mutant genes of a tested sample of a target object on expression activity of each gene in a predetermined genome, wherein the predetermined genome corresponds to the disease; and outputting, by the electronic apparatus, predictive data of at least one treatment management factor characteristic of the target object relative to the disease based on the concerted effect burden parameter data.

Abstract: Methods for preparing a catalyst precursor material from dihalo-substituted metalloids are provided. The methods In include mixing a first solution of a halogenated alkane, at least one solvent, and a first component selected from a dihalo-substituted-group-14 metalloid or an organolithium reagent in a first reaction zone. Continuously adding the first solution to a second reaction zone, and continuously adding a second solution to the second reaction zone. The second solution including at least one solvent and a second component of either the dihalo-substituted-group-14 metalloid or the organolithium reagent, the second component is different from the first component. Mixing the first solution and the second solution in the second reaction zone.

Abstract: Methods for preparing 5-fluoro-6-(bromo or chloro)picloram analogs, or derivatives thereof, from picloram acid, picloram ester, or the nitrile analog of picloram are provided. The methods include chemical process steps that: (1) introduce a phthaloyl group onto the 4-amino substituent of picloram acid, picloram ester, or the nitrile analog of picloram, (2) add 2 fluorine atoms at the 5,6-positions of the pyridine ring using halex fluorination chemistry, (3) remove the phthaloyl group, hydrolyze the ester or nitrile substituent, and add chlorine or bromine to the 6-position by treatment with an acid and water, and finally, (4) esterify the 5-fluoro-6-(bromo or chloro)picloram acid produced in step (3) to a 5-fluoro-6-(bromo or chloro)picloram ester.

Abstract: The present application discloses a method for acquiring intracellular deterministic event, an electronic device and a storage medium, the method includes: acquiring several mutant genes of a detected object; acquiring driving force information of each of the several mutant genes for changes of each gene in a predetermined genome; acquiring driving force information of the several mutant genes for changes of each gene in the predetermined genome according to the acquiring driving force information of each of the several mutant genes for changes of each gene in the predetermined genome; and determining at least onepredetermined type of intracellular deterministic event information of the detected object according to the driving force information of the several mutant genes for changes of each gene in the predetermined genome.

Abstract: A method for predicting a risk of suffering from a disease, includes: acquiring driving force information of mutant genes belonging to a pre-determined genome of a detected object for changes in activity of a plurality of pre-determined signaling pathways; acquiring driving force information of mutant genes belonging to a pre-determined genome of each reference object in first and second reference object groups for the changes in the activity of the plurality of pre-determined signaling pathways; where each reference object in the first reference object group belongs to a healthy object, and each reference object in the second reference object group belongs to an object suffering from a specific disease; performing a first clustering on the detected object, and each reference object in the first and second reference object groups; and outputting a risk of the detected object suffering from the specific disease.

Abstract: Embodiments are directed to a catalyst system comprising metal ligand complexes and processes for polyolefin polymerization using the metal ligand complex having the following structure: Formula I.

Abstract: Addition curing electrically conductive liquid silicone rubber (LSR) compositions, their methods of preparation, and cured elastomeric products made from the compositions are provided. The compositions are cured to form elastomeric products suitable for high voltage applications such as cable joints, cable terminal applications, cable accessories and connectors. In general, the composition comprises: (a) at least one polydiorganosiloxane having at least two alkenyl groups per molecule: (b) at least one organohydrogenpolysiloxane: (c) at least one reinforcing filler: (d) at least one hydrosilylation catalyst: and (e) an electrically conductive filler. Component (e) comprises: (i) extra conductive carbon black: and (ii) single walled carbon nanotubes.

Abstract: Methods for preparing 5-fluoro-6-(bromo or chloro)picloram analogs, or derivatives thereof, from picloram acid, picloram ester, or the nitrile analog of picloram are provided. The methods include chemical process steps that: (1) introduce a phthaloyl group onto the 4-amino substituent of picloram acid, picloram ester, or the nitrile analog of picloram, (2) add 2 fluorine atoms at the 5,6-positions of the pyridine ring using halex fluorination chemistry, (3) remove the phthaloyl group, hydrolyze the ester or nitrile substituent, and add chlorine or bromine to the 6-position by treatment with an acid and water, and finally, (4) esterify the 5-fluoro-6-(bromo or chloro)picloram acid produced in step (3) to a 5-fluoro-6-(bromo or chloro)picloram ester.

Abstract: Embodiments are directed to a metal complex formed, wherein the metal complexes are used as pro-catalyst in polyolefin polymerization and comprise the following structure (Formula (I)).

Abstract: The present invention discloses a tapping shank which mainly consists of axial, radial and deflection comprehensive floating mechanisms and a high-sensitivity rolling clutch safety mechanism. The present invention has an actual safety guarantee in tapping an M1 thread, solves the problems of axial pressure and tension of a main shaft on a screw tap, and eccentric and deflection errors between the screw tap and a bottom hole, ensures the precision of a hole diameter and a longest service life of the screw tap, and is also a high-precision hole machining floating reamer shank.

Abstract: Embodiments are directed to a metal complex formed, wherein the metal complexes are used as pro-catalyst in polyolefin polymerization and comprise the following structure (Formula (I)).

Abstract: The disclosure provides a procatalyst for the polymerization of ethylene and optionally one or more alpha-olefins having the structure shown in formula (I) below: wherein at least two of Y1-Y3 and at least two of Y4-Y6 are fluorine atoms and when only two of Y1-Y3 and only two of Y4-Y6 are fluorine atoms, the non-fluorine Y1-Y6 are selected from the group consisting of H atom, alkyl groups, aryl groups, heteroaryl groups, and alkoxy groups. Also provided is a polymerization process using the procatalyst.