Patents by Inventor Clark A. Sehon

Clark A. Sehon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210253532
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: January 22, 2021
    Publication date: August 19, 2021
    Inventors: Niall Andrew Anderson, Deepak Bandyopadhyay, Alain Claude-Marie Daugan, Frederic G. Donche, Patrick M. Eidam, Nicolas Eric Faucher, Nicolas S. George, Philip Anthony Harris, Jae U. Jeong, Bryan W. King, Clark A. Sehon, Gemma Victoria White, David Duff Wisnoski
  • Patent number: 10940154
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: March 9, 2021
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jae U. Jeong, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, Jr., Daohua Zhang
  • Patent number: 10933070
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: March 2, 2021
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jae U. Jeong, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, Jr., Daohua Zhang
  • Patent number: 10899716
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: January 26, 2021
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Niall Andrew Anderson, Deepak Bandyopadhyay, Alain Claude-Marie Daugan, Frederic G. Donche, Patrick M. Eidam, Nicolas Eric Faucher, Nicolas S. George, Philip Anthony Harris, Jae U. Jeong, Bryan W. King, Clark A. Sehon, Gemma Victoria White, David Duff Wisnoski
  • Publication number: 20200165205
    Abstract: Disclosed are compounds having the formula: wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: January 31, 2020
    Publication date: May 28, 2020
    Inventors: Niall Andrew ANDERSON, Deepak BANDYOPADHYAY, Alain Claude-Marie DAUGAN, Frederic G. DONCHE, Patrick M. EIDAM, Nicolas Eric FAUCHER, Nicolas S. GEORGE, Philip Anthony HARRIS, Jae U. JEONG, Bryan W. KING, Clark A. SEHON, Gemma Victoria WHITE, David Duff WISNOSKI
  • Patent number: 10590085
    Abstract: Disclosed are compounds having the formula (I): wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: March 17, 2020
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Niall Andrew Anderson, Deepak Bandyopadhyay, Alain Claude-Marie Daugan, Frederic G. Donche, Patrick M. Eidam, Nicolas Eric Faucher, Nicolas S. George, Philip Anthony Harris, Jae U. Jeong, Bryan W. King, Clark A. Sehon, Gemma Victoria White, David Duff Wisnoski
  • Publication number: 20190262356
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 10, 2019
    Publication date: August 29, 2019
    Inventors: Jae U. JEONG, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, JR., Daohua Zhang
  • Publication number: 20190201413
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 4, 2019
    Inventors: Jae U. JEONG, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, JR., Daohua Zhang
  • Patent number: 10292987
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: May 21, 2019
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Jae U. Jeong, Deepak Bandyopadhyay, Patrick M. Eidam, Philip Anthony Harris, Jianxing Kang, Bryan Wayne King, Ami Lakdawala Shah, Lara Kathryn Leister, Attiq Rahman, Joshi M. Ramanjulu, Clark A. Sehon, Robert Singhaus, Jr., Daohua Zhang
  • Publication number: 20180134665
    Abstract: Disclosed are compounds having the formula (I): wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 19, 2016
    Publication date: May 17, 2018
    Inventors: Niall Andrew ANDERSON, Deepak BANDYOPADHYAY, Alain Claude-Marie DAUGAN, Frederic G. DONCHE, Patrick M. EIDAM, Nicolas Eric FAUCHER, Nicolas S. GEORGE, Philip Anthony HARRIS, Jae U. JEONG, Bryan W. KING, Clark A. SEHON, Gemma Victoria WHITE, David Duff WISNOSKI
  • Publication number: 20170008878
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A. L, and B are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: September 21, 2016
    Publication date: January 12, 2017
    Inventors: Deepak BANDYOPADHYAY, Patrick M. EIDAM, Peter J. GOUGH, Philip Anthony HARRIS, Jae U. JEONG, Jianxing KANG, Bryan Wayne KING, Ami LAKDAWALA SHAH, Lara Kathryn LEISTER, Robert W. MARQUIS, JR., Attiq RAHMAN, Joshi M. RAMANJULU, Clark A. SEHON, Robert SINGHAUS, JR., Daohua ZHANG
  • Publication number: 20160060222
    Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: November 6, 2015
    Publication date: March 3, 2016
    Inventors: Michael Jonathan BURY, Linda N. CASILLAS, Adam Kenneth CHARNLEY, Michael P. DeMARTINO, Xiaoyang DONG, Patrick EIDAM, Pamela A. HAILE, Philip Anthony HARRIS, Ami Lakdawala SHAH, Bryan W. KING, Robert W. MARQUIS, JR., John F. MEHLMANN, Joseph J. ROMANO, Clark A. SEHON
  • Publication number: 20150353533
    Abstract: Disclosed are compounds having the formula: wherein X, Y, Z1, Z2, Z3, Z4, R5, RA, m, A, L, and B are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: February 14, 2014
    Publication date: December 10, 2015
    Inventors: Deepak BANDYOPADHYAY, Patrick M. EIDAM, Peter J. GOUGH, Philip Anthony HARRIS, Jae U. JEONG, Jianxing KANG, Bryan Wayne KING, Ami LAKDAWALA SHAH, Lara Kathryn LEISTER, Robert W. MARQUIS, JR., Attiq RAHMAN, Joshi M. RAMANJULU, Clark A. SEHON, Robert SINGHAUS, JR., Daohua ZHANG
  • Patent number: 8563722
    Abstract: The present invention relates to a method comprising reducing a ketone of formula I: with an enantioselective hydrogenating agent to form substantially enantiomerically pure alcohol of formula II: where R—R4 and m are as defined herein. The method of the present invention is useful for making CCR2 modulators as wells as precursors CCR2 modulators.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: October 22, 2013
    Assignee: Glaxo Group Limited
    Inventors: Pamela A. Haile, Clark A. Sehon, Huan Wang
  • Patent number: 8431590
    Abstract: The present invention relates to a compound of the following formula: where R1-R6, R10, Y, n, m, p, and q are as defined herein. Compounds and compositions of the present invention are useful for the treatment of diseases associated with the overexpression of CCR2.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: April 30, 2013
    Assignee: Glaxo Group Limited
    Inventors: Brian W. Budzik, Hilary Schenck Eidam, Ryan Michael Fox, Krista B. Goodman, Dimitar B. Gotchev, Pamela A. Haile, Terry Vincent Hughes, Ronggang Liu, Nathan A. Miller, Tamara Ann Miskowski, Clark A. Sehon, Andrew Q. Viet, Gren Z. Wang, Jing Zhang
  • Publication number: 20130053375
    Abstract: Disclosed are quinoline compounds having the formula: wherein R1, R2 and A are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: May 6, 2011
    Publication date: February 28, 2013
    Inventors: Michael Jonathan Bury, Linda N. Casillas, Adam Kenneth Charnley, Michael P. DeMartino, Xiaoyang Dong, Patrick Eidam, Pamela A. Haile, Philip Anthony Harris, Ami Lakdawala Shah, Bryan W. King, Robert W. Marquis, JR., John F. Mehlmann, Joseph J. Romano, Clark A. Sehon
  • Publication number: 20130023532
    Abstract: Disclosed are compounds having the formula: or a salt thereof, wherein A, n, R1, R1A, and R2 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: March 26, 2011
    Publication date: January 24, 2013
    Inventors: Linda N. Casillas, Subhas J. Chakravorty, Adam Kenneth Charnley, Pamela A. Haile, Terry Vincent Hughes, Jae U. Jeong, Jianxing Kang, Ami Lakdawala Shah, Lara Kathryn Leister, Robert W. Marquis, JR., Nathan Andrew Miller, Daniel J. Price, Clark A. Sehon, Gren Z. Wang, Daohua Zhang, Patrick Eidam
  • Publication number: 20130023534
    Abstract: Disclosed are compounds having the formula (I): wherein Z, n, R1, R1A, R3, R4, and R5 are as defined herein, and methods of making and using the same.
    Type: Application
    Filed: March 26, 2011
    Publication date: January 24, 2013
    Inventors: Linda N. Casillas, Subhas J. Chakravorty, Patrick Eidam, Pamela A. Haile, Terry Vincent Hughes, Ami Lakdawala Shah, Lara Kathryn Leister, Nathan Andrew Miller, Attiq Rahman, Clark A. Sehon, Gren Z. Wang, Daohua Zhang
  • Publication number: 20110306765
    Abstract: The present invention relates to a method comprising reducing a ketone of formula I: with an enantioselective hydrogenating agent to form substantially enantiomerically pure alcohol of formula II: where R—R4 and m are as defined herein. The method of the present invention is useful for making CCR2 modulators as wells as precursors CCR2 modulators.
    Type: Application
    Filed: February 23, 2010
    Publication date: December 15, 2011
    Inventors: Pamela A. Haile, Clark A. Sehon, Huan Wang
  • Publication number: 20110124671
    Abstract: The present invention relates to a compound of the following formula: or a pharmaceutically acceptable salt thereof; where R1-R5, Y, m, n, and p are defined herein. Compounds and compositions of the present invention are useful the treatment of atherosclerosis.
    Type: Application
    Filed: August 14, 2008
    Publication date: May 26, 2011
    Inventors: Brian W. Budzik, Michael Jonathan Bury, Minghua Gu, Ronggang Liu, Feng Ren, Clark A. Sehon, Gren Z. Wang, Jing Zhang