Patents by Inventor Clive Svendsen

Clive Svendsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABILIZATION APPARATUSES AND METHODS FOR MEDICAL PROCEDURES
    Publication number: 20160100897
    Abstract: The present invention teaches minimally invasive apparatuses and methods for stabilizing and/or guiding medical instruments used in a variety of medical procedures, including (a) introducing one or more substances into a subject's body, (b) removing one or more substances from a subject's body, (c) manipulating a region of a subject's body, or (d) combinations thereof. Among the many advantages of the inventive apparatuses are their simplicity and adaptability to attach to a variety of retractors.
    Type: Application
    Filed: April 30, 2014
    Publication date: April 14, 2016
    Applicant: Cedars-Sinai Medical Center
    Inventors: Pablo Avalos, Doniel Drazin, Clive Svendsen
  • In Vitro Model Of Spinal Muscular Atrophy
    Publication number: 20120264648
    Abstract: A population of iPS cells derived from somatic cells from a spinal muscular atrophy patient is disclosed. In one embodiment of the invention, the cells have been cultured to produce neural cells. In another embodiment, the invention is a method of testing compounds for their ability to modify cellular SMN levels comprising the steps of obtaining a population of iPS cells derived from a spinal muscular atrophy patient or cells derived from the iPS cells, and examining the effect of a test compound on SMN levels.
    Type: Application
    Filed: April 19, 2012
    Publication date: October 18, 2012
    Inventors: Clive Svendsen, Allison Ebert
  • In vitro model of spinal muscular atrophy
    Patent number: 8211631
    Abstract: A population of iPS cells derived from somatic cells from a spinal muscular atrophy patient is disclosed. In one embodiment of the invention, the cells have been cultured to produce neural cells. In another embodiment, the invention is a method of testing compounds for their ability to modify cellular SMN levels comprising the steps of obtaining a population of iPS cells derived from a spinal muscular atrophy patient or cells derived from the iPS cells, and examining the effect of a test compound on SMN levels.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: July 3, 2012
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Clive Svendsen, Allison Ebert
  • In vitro model of spinal muscular atrophy
    Publication number: 20100279893
    Abstract: A population of iPS cells derived from somatic cells from a spinal muscular atrophy patient is disclosed. In one embodiment of the invention, the cells have been cultured to produce neural cells. In another embodiment, the invention is a method of testing compounds for their ability to modify cellular SMN levels comprising the steps of obtaining a population of iPS cells derived from a spinal muscular atrophy patient or cells derived from the iPS cells, and examining the effect of a test compound on SMN levels.
    Type: Application
    Filed: December 18, 2009
    Publication date: November 4, 2010
    Inventors: Clive Svendsen, Allison Ebert
  • Blood-Brain Barrier Model
    Publication number: 20080044847
    Abstract: A method of creating a multicellular blood-brain barrier model is disclosed. In one embodiment, the method comprises culturing primary brain microvascular endothelial cells or embryonic stem cell-derived endothelial cells upon a permeable support in the presence of neural progenitor cells.
    Type: Application
    Filed: June 21, 2007
    Publication date: February 21, 2008
    Inventors: Eric Shusta, Christian Weidenfeller, Clive Svendsen