Patents by Inventor Cornelia Hertel

Cornelia Hertel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole derivatives as H3 inverse agonists
    Publication number: 20050282864
    Abstract: The present invention relates to compounds of formula I: wherein X, R1, R2, R3, R4 and R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof, to the preparation of such compounds and pharmaceutical compositions containing them. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.
    Type: Application
    Filed: June 20, 2005
    Publication date: December 22, 2005
    Inventors: Silvia McArthur, Cornelia Hertel, Matthias Nettekoven, Susanne Raab, Olivier Roche, Rosa Rodriguez-Sarmiento, Franz Schuler, Jean Marc Plancher
  • Fluorescently labeled growth hormone secretagogue
    Publication number: 20050085421
    Abstract: The present invention relates to a fluorescently labeled growth hormone secretagogue which can be used for the identification of compounds capable of binding to growth hormone secretagogue receptors, in particular by high throughput screening.
    Type: Application
    Filed: October 14, 2004
    Publication date: April 21, 2005
    Inventors: Thilo Enderle, Martin Graf, Cornelia Hertel, Sannah Zoffmann, Eric Kitas
  • D-proline derivatives
    Patent number: 6740760
    Abstract: New compounds have the formula: wherein R, R1, X and Y have the meanings described herein. Methods are set forth for synthesizing these compounds and using these compounds to treat diseases associated with amyloidosis, such as Alzheimer's disease, maturity onset diabetes mellitus, familial amyloid polyneuropathy, scrapie, and Kreuzfeld-Jacob disease.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: May 25, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Cornelia Hertel, Torsten Hoffmann, Roland Jakob-Roetne, Roger David Norcross
  • D-proline derivatives
    Publication number: 20030100770
    Abstract: New compounds have the formula: 1
    Type: Application
    Filed: July 1, 2002
    Publication date: May 29, 2003
    Inventors: Cornelia Hertel, Torsten Hoffmann, Roland Jakob-Roetne, Roger D. Norcross
  • D-proline derivatives
    Patent number: 6512001
    Abstract: New compounds have the formula: wherein R, R1, X and Y have the meanings described herein. Methods are set forth for synthesizing these compounds and using these compounds to treat diseases associated with amyloidosis, such as Alzheimer's disease, maturity onset diabetes mellitus, familial amyloid polyneuropathy, scrapie, and Kreuzfeld-Jacob disease.
    Type: Grant
    Filed: August 10, 2000
    Date of Patent: January 28, 2003
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Cornelia Hertel, Torsten Hoffmann, Roland Jakob-Roetne, Roger David Norcross
  • D-proline derivatives
    Patent number: 6262089
    Abstract: New compounds have the formula: wherein R, R1, X and Y have the meanings described herein. Methods are set forth for synthesizing these compounds and using these compounds to treat diseases associated with amyloidosis, such as Alzheimer's disease, maturity onset diabetes mellitus, familial amyloid polyneuropathy, scrapie, and Kreuzfeld-Jacob disease.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: July 17, 2001
    Assignee: Hoffman-La Roche Inc.
    Inventors: Cornelia Hertel, Torsten Hoffmann, Roland Jakob-Roetne, Roger David Norcross
  • D-proline derivatives
    Patent number: 6103910
    Abstract: New compounds have the formula: ##STR1## wherein R, R.sup.1, X and Y have the meanings described herein. Methods are set forth for synthesizing these compounds and using these compounds to treat diseases associated with amyloidosis, such as Alzheimer's disease, maturity onset diabetes mellitus, familial amyloid polyneuropathy, scrapie, and Kreuzfeld-Jacob disease.
    Type: Grant
    Filed: October 27, 1998
    Date of Patent: August 15, 2000
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Cornelia Hertel, Torsten Hoffmann, Roland Jakob-Roetne, Roger David Norcross