Patents by Inventor Craig Alan COBURN

Craig Alan COBURN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF
    Publication number: 20190169164
    Abstract: Benzazepine compounds, conjugates, and pharmaceutical compositions for use in the treatment of disease, such as cancer, are disclosed herein. The disclosed benzazepine compounds are useful, among other things, in the treating of cancer and modulating TLR8. Additionally, benzazepine compounds incorporated into a conjugate with an antibody construct are described herein.
    Type: Application
    Filed: February 12, 2019
    Publication date: June 6, 2019
    Inventors: Craig Alan Coburn, Peter Robert Baum, Sean Wesley Smith
  • BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF
    Publication number: 20190169165
    Abstract: Benzazepine compounds, conjugates, and pharmaceutical compositions for use in the treatment of disease, such as cancer, are disclosed herein. The disclosed benzazepine compounds are useful, among other things, in the treating of cancer and modulating TLR8. Additionally, benzazepine compounds incorporated into a conjugate with an antibody construct are described herein.
    Type: Application
    Filed: February 12, 2019
    Publication date: June 6, 2019
    Inventors: Craig Alan COBURN, Peter Robert BAUM, Sean Wesley SMITH
  • Substituted heterocycles as bromodomain inhibitors
    Patent number: 10292968
    Abstract: The present application relates to substituted heterocycles compound of Formula I and pharmaceutical compositions thereof useful for the inhibition of BET protein function by binding to bromodomains (Formula I).
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: May 21, 2019
    Assignee: Zenith Epigenetics Ltd.
    Inventors: Samuel David Brown, Craig Alan Coburn, Olesya Kharenko
  • Benzazepine compounds, conjugates, and uses thereof
    Patent number: 10239862
    Abstract: Benzazepine compounds, conjugates, and pharmaceutical compositions for use in the treatment of disease, such as cancer, are disclosed herein. The disclosed benzazepine compounds are useful, among other things, in the treating of cancer and modulating TLR8. Additionally, benzazepine compounds incorporated into a conjugate with an antibody construct are described herein.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: March 26, 2019
    Assignee: SILVERBACK THERAPEUTICS, INC.
    Inventors: Craig Alan Coburn, Peter Robert Baum, Sean Wesley Smith
  • BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF
    Publication number: 20190062306
    Abstract: Benzazepine compounds, conjugates, and pharmaceutical compositions for use in the treatment of disease, such as cancer, are disclosed herein. The disclosed benzazepine compounds are useful, among other things, in the treating of cancer and modulating TLR8. Additionally, benzazepine compounds incorporated into a conjugate with an antibody construct are described herein.
    Type: Application
    Filed: March 14, 2018
    Publication date: February 28, 2019
    Inventors: Craig Alan Coburn, Peter Robert Baum, Sean Wesley Smith
  • SUBSTITUTED BICYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS
    Publication number: 20190055235
    Abstract: The present disclosure relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Application
    Filed: December 16, 2015
    Publication date: February 21, 2019
    Inventors: Samuel David Brown, Craig Alan COBURN
  • BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF
    Publication number: 20180258048
    Abstract: Benzazepine compounds, conjugates, and pharmaceutical compositions for use in the treatment of disease, such as cancer, are disclosed herein. The disclosed benzazepine compounds are useful, among other things, in the treating of cancer and modulating TLR8. Additionally, benzazepine compounds incorporated into a conjugate with an antibody construct are described herein.
    Type: Application
    Filed: May 7, 2018
    Publication date: September 13, 2018
    Inventors: Craig Alan Coburn, Peter Robert Baum, Sean Wesley Smith
  • SUBSTITUTED HETEROCYCLES AS BROMODOMAIN INHIBITORS
    Publication number: 20170360756
    Abstract: The present application relates to substituted heterocycles compound of Formula I and pharmaceutical compositions thereof useful for the inhibition of BET protein function by binding to bromodomains (Formula I).
    Type: Application
    Filed: December 11, 2015
    Publication date: December 21, 2017
    Inventors: Samuel David BROWN, Craig Alan COBURN, Oiesya KHARENKO