Patents by Inventor Craig E. Masse

Craig E. Masse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TYK2 INHIBITORS, USES, AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20180258086
    Abstract: The present invention provides compounds useful as inhibitors of Tyrosine Kinase 2 (Tyk2), solid forms and compositions thereof, methods of producing the same, and methods of using the same in the treatment of Tyk2-mediated diseases.
    Type: Application
    Filed: March 7, 2018
    Publication date: September 13, 2018
    Inventors: Jeremy Robert Greenwood, Craig E. Masse, Jon P. Lawson, Jean-Baptiste Arlin, David Pearson, Jonathan James Loughrey
  • TYK2 inhibitors and uses thereof
    Patent number: 10023571
    Abstract: The present invention provides compounds of formula I, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: July 17, 2018
    Assignee: Nimbus Lakshimi, Inc.
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Donna L. Romero, Geraldine C. Harriman, Ronald T. Wester, Mee Shelley, Joshua Jahmil Kennedy-Smith, Markus Dahlgren, Sayan Mondal, Shaughnessy Robinson
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20180155349
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: October 13, 2017
    Publication date: June 7, 2018
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • Bicyclic compounds as ACC inhibitors and uses thereof
    Patent number: 9988399
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: June 5, 2018
    Assignee: Gilead Apollo, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20180134700
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: October 20, 2017
    Publication date: May 17, 2018
    Inventors: Jeremy Robert Greenwood, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • ACC inhibitors and uses thereof
    Patent number: 9944655
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: April 17, 2018
    Assignee: Gilead Apollo, LLC
    Inventors: Geraldine C. Harriman, Craig E. Masse, H. James Harwood, Sathesh Bhat, Jeremy Robert Greenwood
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20170305933
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: May 9, 2017
    Publication date: October 26, 2017
    Inventors: Markus Dahlgren, Jeremy Robert Greenwood, Geraldine C. Harriman, Joshua Jahmil Kennedy-Smith, Craig E. Masse, Donna L. Romero, Mee Shelley, Ronald T. Wester
  • ACC inhibitors and uses thereof
    Patent number: 9765089
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: September 19, 2017
    Assignee: Gilead Apollo, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • IRAK inhibitors and uses thereof
    Patent number: 9751892
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: September 5, 2017
    Assignee: Nimbus Iris, Inc.
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, Rosana Kapeller-Libermann, Craig E. Masse, Shaughnessy Robinson, Donna L. Romero, Mee Shelley, Ronald T. Wester
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20170247373
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: March 13, 2017
    Publication date: August 31, 2017
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Donna L. Romero, Geraldine C. Harriman, Ronald T. Wester, Mee Shelley, Joshua Jahmil Kennedy-Smith, Markus Dahlgren
  • Derivatives of pyrazole-substituted amino-heteroaryl compounds
    Patent number: 9707218
    Abstract: This invention relates to novel pyrazole-substituted amino-heteroaryl compounds of Formula I: and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering an inhibitor of anaplastic lymphoma kinase (ALK).
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: July 18, 2017
    Assignee: Concert Pharmaceuticals, Inc.
    Inventors: Bhaumik A. Pandya, Craig E. Masse, Ian Robert Silverman, Roger D. Tung
  • TYK2 inhibitors and uses thereof
    Patent number: 9630970
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: April 25, 2017
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Donna L. Romero, Geraldine C. Harriman, Ronald T. Wester, Mee Shelley, Joshua Jahmil Kennedy-Smith, Markus Dahlgren
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20170066763
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: September 1, 2016
    Publication date: March 9, 2017
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Donna L. Romero, Geraldine C. Harriman, Ronald T. Wester, Mee Shelley, Joshua Jahmil Kennedy-Smith, Markus Dahlgren, Sayan Mondal
  • IRAK INHIBITORS AND USES THEREOF
    Publication number: 20170035766
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: August 11, 2016
    Publication date: February 9, 2017
    Inventors: Donna Romero, Craig E. Masse, Shaughnessy Robinson, Jeremy Robert Greenwood, Geraldine C. Harriman
  • IRAK inhibitors and uses thereof
    Patent number: 9518065
    Abstract: The present invention provides compounds of the general formula I: or a pharmaceutically acceptable salt thereof, wherein each variable is as defined and described herein, as inhibitors of one or more interleukin-1 receptor-associated kinases (“IRAK”).
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: December 13, 2016
    Assignee: Nimbus Iris, Inc.
    Inventors: Donna Romero, Craig E. Masse, Shaughnessy Robinson, Jeremy Robert Greenwood, Geraldine C. Harriman
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20160297826
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: April 13, 2016
    Publication date: October 13, 2016
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Donna L. Romero, Geraldine C. Harriman, Ronald T. Wester, Mee Shelley, Joshua Jahmil Kennedy-Smith, Markus Dahlgren
  • ACC INHIBITORS AND USES THEREOF
    Publication number: 20160297834
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: March 11, 2016
    Publication date: October 13, 2016
    Inventors: Geraldine C. Harriman, Craig E. Masse, James Harwood, Sathesh Bhat, Jeremy Robert Greenwood
  • IRAK INHIBITORS AND USES THEREOF
    Publication number: 20160296524
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: April 13, 2016
    Publication date: October 13, 2016
    Inventors: Donna L. Romero, Matthew David Wessel, Shaughnessy Robinson, Jeremy Robert Greenwood, Karl Shawn Watts, Leah Lynn Frye, Geraldine C. Harriman, Alan Franklin Corin, Craig E. Masse, Mee Shelley
  • ACC inhibitors and uses thereof
    Patent number: 9453026
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: September 27, 2016
    Assignee: Gilead Apollo, Inc.
    Inventors: Geraldine C. Harriman, Craig E. Masse, James Harwood, Sathesh Bhat, Jeremy Robert Greenwood
  • Synthesis of deuterated morpholine derivatives
    Patent number: 9453009
    Abstract: The present invention is directed to a process for preparing a 2,26,6-d4-morpholine derivative represented by Structural Formula (I): or a salt thereof.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: September 27, 2016
    Assignee: Concert Pharmaceuticals, Inc.
    Inventors: Julie F. Liu, Xuejun Tang, Scott L. Harbeson, Craig E. Masse