Abstract: The present invention describes a self mode locking laser and a method for self mode locking a laser. The laser (1) comprises a resonator terminated by first (3) and second (4) mirrors and folded by a third mirror (5). The third mirror comprises a single distributed Bragg reflector (17) upon which is mounted a multilayer semiconductor gain medium (18) and which includes at least one quantum well layer and an optical Kerr lensing layer (22). Self mode locking may be achieved by configuring the laser resonator such that the lensing effect of the Kerr lensing layer acts to reduce an astigmatism deliberately introduced to the cavity mode. The self mode locking of the laser may be further enhanced by selecting the length of the resonator such that a round trip time of a cavity mode is matched with an upper-state lifetime of one or more semiconductor carriers located within the gain medium.

Abstract: An optical amplifier is described. The optical amplifier (1) comprises a semiconductor disk gain medium (2) including at least one quantum well layer (9) and a pump field source (17) for generating an optical pump field (3) for the semiconductor disk gain medium. The optical amplifier acts to generate an output optical field (5) from an input optical field (4) received by the optical amplifier and arranged to be incident upon the semiconductor disk gain medium. Employing a semiconductor disk gain medium within the optical amplifier allows it to be optically pumped and thus provided for increased stability and beam quality of the output optical field while allowing for the design of optical amplifiers which can operate across a broad range of wavelengths. The optical amplifier may be employed with continuous wave or pulsed input optical fields.

Abstract: A self mode locking laser and corresponding method is described. The laser comprises a resonator (2) terminated by first (3) and second (4) mirrors and folded by a third mirror (5). The third mirror comprises a reflector (15) surmounted by a multilayer semiconductor gain medium (16) that includes at least one quantum well layer and an optical Kerr lensing layer (20). A perturbator is also included that provides a means to induce a perturbation on an intensity of one or more cavity modes of the resonator. The pertubator is employed to induce a small perturbation on the intensity of the cavity modes of the resonator which is sufficient for the optical Kerr lensing layer to induce mode locking on the output field. The second mirror (4) comprises an intensity saturable mirror that provides a means for reducing the pulse widths of the generated output field e.g. to around 100 fs.

Abstract: The present invention describes a self mode locking laser and a method for self mode locking a laser. The laser (1) comprises a resonator terminated by first (3) and second (4) mirrors and folded by a third mirror (5). The third mirror comprises a single distributed Bragg reflector (17) upon which is mounted a multilayer semiconductor gain medium (18) and which includes at least one quantum well layer and an optical Kerr lensing layer (22). Self mode locking may be achieved by configuring the laser resonator such that the lensing effect of the Kerr lensing layer acts to reduce an astigmatism deliberately introduced to the cavity mode. The self mode locking of the laser may be further enhanced by selecting the length of the resonator such that a round trip time of a cavity mode is matched with an upper-state lifetime of one or more semiconductor carriers located within the gain medium.

Abstract: The present invention describes a mode locking semiconductor disk laser (SDL). The laser comprises a resonator terminated by first and second mirrors (6,7) and folded by a third mirror. The third mirror or comprising a semiconductor disk laser (8) suitable for generating a resonator field comprising a predetermined central wavelength A0 while the second mirror comprising an intensity saturable mirror (7) suitable for mode locking the resonator field at the predetermined wavelength. The reflectivity of the of the resonator at the central wavelength A0 is reduced by shifting the reflectivity profiles of the first and or second mirrors to wavelength shorter than the predetermined wavelength so as to suppress gain at wavelengths longer than the central wavelength A0. By mismatching the reflectivity profile (32) of the second mirror (7) to that of the desired output wavelength (3) provides a stable mode locked laser with significantly reduced noise.

Abstract: The present invention describes a method and apparatus for mounting a semiconductor disc laser (SDL). In particular there is described a cooling apparatus assembly (12) for mounting the semiconductor disc laser (1) the cooling apparatus assembly comprising a crystalline heat spreader (8) made of diamond, sapphire or SiC and optically contacted to the SDL (1). The apparatus further comprises a heatsink (13) made of copper and a recess (16) located on a first surface (15) of the heatsink. A pliable filler material (17) which may be In or an In alloy is provided within the recess (16) such that when a sealing plate (19) is fastened to the heatsink the SDL (1) is hermetically sealed within the recess. Hermetically sealing the SDL within the recess is found to significantly increase the lifetime of the device comprising the SDL. The heat sink (13) may be water cooled with pipes (14) delivering the water. In case the sealing plate (19) is made from for example Invar, it has an aperture (20).

Abstract: (S)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinoline carboxylic acid in substantially pure form is described together with its sodium salt and solvates. Methods for preparing the compound, its sodium salt and its solvates and pharmaceutical compositions comprising them are also described.

Abstract: (S)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinoline carboxylic acid in substantially pure form is described together with its sodium salt and solvates. Methods for preparing the compound, its sodium salt and its solvates and pharmaceutical compositions comprising them are also described.

Abstract: The present invention describes a self mode locking laser and a method for self mode locking a laser. The laser (1) comprises a resonator terminated by first (3) and second (4) mirrors and folded by a third mirror (5). The third mirror comprises a single distributed Bragg reflector (17) upon which is mounted a multilayer semiconductor gain medium (18) and which includes at least one quantum well layer and an optical Kerr lensing layer (22). Self mode locking may be achieved by configuring the laser resonator such that the lensing effect of the Kerr lensing layer acts to reduce an astigmatism deliberately introduced to the cavity mode. The self mode locking of the laser may be further enhanced by selecting the length of the resonator such that a round trip time of a cavity mode is matched with an upper-state lifetime of one or more semiconductor carriers located within the gain medium.

Abstract: The present invention describes a self mode locking laser and a method for self mode locking a laser. The laser (1) comprises a resonator terminated by first (3) and second (4) mirrors and folded by a third mirror (5). The third mirror comprises a single distributed Bragg reflector (17) upon which is mounted a multilayer semiconductor gain medium (18) and which includes at least one quantum well layer and an optical Kerr lensing layer (22). Self mode locking may be achieved by configuring the laser resonator such that the lensing effect of the Kerr lensing layer acts to reduce an astigmatism deliberately introduced to the cavity mode. The self mode locking of the laser may be further enhanced by selecting the length of the resonator such that a round trip time of a cavity mode is matched with an upper-state lifetime of one or more semiconductor carriers located within the gain medium.

Abstract: The system of the present disclosure enables a filter cartridge having an array of filter media tubes to be remotely selectively back flushed during service by sequentially flushing the tubes with the rotary valving element to permit removal of trapped filtered material in service without disrupting the filtering flow in the balance of the filter array.

Abstract: (S)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinoline carboxylic acid in substantially pure form is described together with its sodium salt and solvates. Methods for preparing the compound, its sodium salt and its solvates and pharmaceutical compositions comprising them are also described.

Abstract: Described is a device for inducing crystal nucleation in a crystalliser. The device comprises a vessel for fluid and a surface abrader, wherein the surface abrader is configured to abrade a surface within the vessel to induce crystal nucleation. The friction of the abrader against the surface within the vessel creates nano-sized particulates which induce crystal nucleation. Crystal growth can then take place in the crystalliser. Also described is a crystallisation apparatus comprising the device and a crystallisation process using the device or similar. The device is significantly cheaper and more reliable than known ultrasound devices and facilitates the separation of crystal nucleation and crystal growth. The device also enables the avoidance of the use of seeding as a source of secondary nucleation.

Abstract: The system of the present disclosure enables a filter cartridge having an array of filter media tubes to be remotely selectively back flushed during service by sequentially flushing the tubes with the rotary valving element to permit removal of trapped filtered material in service without disrupting the filtering flow in the balance of the filter array.

Abstract: A filtration unit contains a plurality of filter housings, each filter housing having a cylindrical shell with a lower port, an upper port, and a filter element. The lower and upper ports direct fluid through the filter housing in a first direction during a filtering cycle and direct fluid through the filter housing in a second direction during a backwashing cycle. The unit also includes a diverter and a servomechanism that rotates the diverter to selectively connect the filter housing to a drain port for the backwashing cycle.

Abstract: (S)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinoline carboxylic acid in substantially pure form is described together with its sodium salt and solvates. Methods for preparing the compound, its sodium salt and its solvates and pharmaceutical compositions comprising them are also described.

Abstract: A system and method for displaying a graphical context menu on a display screen of a mobile communication device. The method includes receiving a menu request, determining the number of menu items based on the context of the menu request, generating a graphical context menu based on the determined number of the determined number of menu items, inserting the menu items into the generated graphical context menu, and displaying the generated graphical context menu on the display screen with the inserted menu items. The graphical context menu can include menu items displayed in a 3×3 grid, a 2×3 grid or a 1×3 grid. The graphical context menu can include a default menu item in the center of the grid and a full menu option in the bottom most right slot of the grid.

Abstract: (S)-2-(Diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinoline carboxylic acid in substantially pure form is described together with its sodium salt and solvates. Methods for preparing the compound, its sodium salt and its solvates and pharmaceutical compositions comprising them are also described.

Abstract: The present invention relates to viral polymerase inhibitors of formula (I), salts, N-oxides, solvates, hydrates, racemates, enantiomers or isomers thereof, processes for their preparation and their use in the treatment of Flaviviridae viral infections such as Hepatitis C virus (HCV) infections:

Abstract: The present invention relates to viral polymerase inhibitors of formula (I), salts, N-oxides, solvates, hydrates, racemates, enantiomers or isomers thereof, processes for their preparation and their use in the treatment of Flaviviridae viral infections such as Hepatitis C virus (HCV) infections: