Abstract: A biostimulator, such as a leadless cardiac pacemaker, including a fixation element to engage tissue and one or more backstop elements to resist back-out from the tissue, is described. The fixation element can be mounted on a housing of the biostimulator such that a helix of the fixation element extends distally to a leading point. The leading point can be located on a distal face of the helix at a position that is proximal from a center of the distal face. The backstop elements can include non-metallic filaments, such as sutures, or can include a pinch point of the biostimulator. The backstop features can grip the tissue to prevent unscrewing of the fixation element. Other embodiments are also described and claimed.

Abstract: A method, a device, and a non-transitory storage medium are described in which an blocking delivery service is provided. The service may use an identifier of a source end device, destination address information associated with a destination end device, and configurable criteria as a basis to block delivery of application service layer data. The service may be configured to apply to end devices based on an addressing scheme of the service. The service may be configured on a network device that provides an application service. The service may block delivery without the use of class of service or subscriber provisioning.

Abstract: Techniques described herein are directed to analyzing intellectual-property data according to provide various intellectual property related services to organizations. In particular implementations, information related to products and/or services may be obtained from a number of data sources. Additionally, information related to intellectual-property assets, such as patents, trademarks, copyrights, trade secrets, and know-how, may be obtained. In various situations, the intellectual-property assets may be mapped to respective products and/or services. The mappings between the products and/or services and intellectual-property assets may be used to provide intellectual property related services that correspond to the intellectual-property assets, such as valuation services, strategy-related services, or risk-related services.

Abstract: Metering dispensers include a body configured to hold a flowable composition in a chamber, a drive screw coupled to the body, and a plunger threadingly coupled to the drive screw. The plunger includes at least two annular lips that form a fluid seal with the chamber as the plunger travels along the drive screw through the chamber. A base is rotationally coupled to the body with a cam that contacts at least one tab extending externally from the body so that the tab enters at least one low point on the cam by traveling over a trailing edge of the low point, and the trailing edge then prevents the tab from exiting the low point in the direction of the trailing edge.

Abstract: The present discussion relates to structures and devices to facilitate application of an ultrasound therapy beam to a target anatomic region in a replicable manner. In certain aspects, adjustable positioning structures are described that allow a general probe positioning structure to be configured for a specific patient in a manner that allows the device to be used repeatedly to target the anatomic region, even when in non-clinical settings. In other aspects, a probe positioning structure is fabricated that is specific to a respective patient anatomy, such that use of the probe positioning structure provides repeatable targeting of the target anatomic region, even when in non-clinical settings.

Abstract: Method and apparatus are described for a system that employs a change management algorithm to drive transfusion “appropriateness” by factoring evidenced-based knowledge and input from practitioners, where said algorithm may also ensure that a blood or blood product transfusion is provided to the right patient, that the blood/blood product is transfused at the right time, and that the procedure is completed for the right reason.

Abstract: Systems and methods for digital property authentication and management are disclosed. A document representing a trade secret may be requested to be registered with a trade secret registry. A document obfuscation value corresponding to the document may be generated and may be registered with a blockchain. A record of the registration may be generated for the trade secret registry. The registry may be searchable and/or offer functionality such as valuation, insurance provision, and/or verification, among other benefits and functionalities.

Abstract: Method and apparatus are described for a system that employs a change management algorithm to drive transfusion “appropriateness” by factoring evidenced-based knowledge and input from practitioners, where said algorithm may also ensure that a blood or blood product transfusion is provided to the right patient, that the blood/blood product is transfused at the right time, and that the procedure is completed for the right reason.

Abstract: Embodiments herein relate to hollow profiles and methods of preparing the same for joining operations. A method herein can include placing a dam within a channel defined by the hollow profile, fitting a die block over an end of the channel, and injecting a flowable composition through an injection port into the channel. Another method can include defining a volume within a first member using at least one flow control device, filling the defined volume with a flowable polymeric composition, allowing the flowable polymeric composition to solidify to form a solid portion in the first member, and mechanically modifying the solid portion to define a joining surface suitable for joining to the second member. Other embodiments are also included herein.

Abstract: A casting core used in the manufacture of a cast engine component for a turbine engine, the cast engine component having a first area, a second area, a fluid passage wall separating the first area and the second area, and a connecting fluid passage extending through the fluid passage wall and interconnecting the first area and the second area. The connecting fluid passage having a turn with a radius (R). The casting core having a first core and a second core. The first core and the second core being defined by a set of geometric characteristics having a first minimum equivalent diameter (D1eqmin) of the first core and a second minimum equivalent diameter (D2eqmin) of the second core. A first flexible geometry factor (FGF1) being equal to: ( D ? 1 eq ? min D ? 2 eq ? min ) ? ( R D ? 2 eq ? min ) .

Abstract: A computer-implemented method for modifying audio-based communications produced during a conference call is disclosed. The computer-implemented method can include monitoring a plurality of utterances transmitted via an audio feed of a device connected to the conference call. The computer-implemented method can identify a first unwanted audio component transmitted via the audio feed. The computer-implemented method can actively modify the audio feed by removing the first unwanted audio component from the audio feed.

Abstract: Provided herein is a system, apparatus, and method for continuous casting of metal, and more particularly, to a mechanism for controlling the shape of a direct chill casting mold to dynamically control a profile of an ingot cast from the mold during the casting process. Embodiments may provide an apparatus for casting material including: first and second opposing side walls; first and second end walls extending between the first and second side walls, where the first and second opposing side walls and the first and second opposing end walls form a generally rectangular shaped mold cavity. At least one of the first and second opposing side walls may include two or more contact regions, where each of the two or more contact regions may be configured to be displaced relative to a straight line along the side wall.

Abstract: An electrical female terminal for mating with a connector assembly generally including a main body, a two-bodied spring, and a wire fastening portion. A protrusion extends from an unattached end portion of the lever member, the protrusion having faces angled relative to each other to efficiently deflect the lever member upwards when the protrusion interacts with an internal protrusion of a housing or a connector assembly. A top portion of the retainer member of the electrical female terminal, located above the two-bodied spring, has a dimple portion. The terminal face or leading end portion of the electrical female terminal is prevented from damaging or cutting a silicone seal. The overstress feature of the tang member of the lever is improved upon by relocating and reshaping the protruding member thereof. The configuration or shape of the cross-section across the upper portion and the support member at the front end portion of the main body of the electrical female terminal is substantially U-shaped.

Abstract: Provided herein are GLP-1 receptor modulator compounds, pharmaceutical compositions, methods of their preparation, and methods of their use in treatment, and/or diagnosis.

Abstract: Provided herein is a system, apparatus, and method for continuous casting of metal, and more particularly, to a mechanism for controlling the shape of a direct chill casting mold to dynamically control a profile of an ingot cast from the mold during the casting process. Embodiments may provide an apparatus for casting material including: first and second opposing side walls; first and second end walls extending between the first and second side walls, where the first and second opposing side walls and the first and second opposing end walls form a generally rectangular shaped mold cavity. At least one of the first and second opposing side walls may include two or more contact regions, where each of the two or more contact regions may be configured to be displaced relative to a straight line along the side wall.

Abstract: Provided herein are GLP-1 receptor modulator compounds, pharmaceutical compositions, methods of their preparation, and methods of their use in treatment, and/or diagnosis.

Abstract: An electrical female terminal for mating with a connector assembly generally including a main body, a two-bodied spring, A protrusion extends from an unattached end portion of the lever member, the protrusion having faces angled relative to each other to efficiently deflect the lever member upwards when the protrusion interacts with an internal protrusion of a housing or a connector assembly, which in turn makes the electrical female terminal more difficult to remove from the housing or the connector assembly to thereby protect the electrical female terminal against the electrical female terminal from falling out during use. A top portion of the retainer member of the electrical female terminal, located above the two-bodied spring, has a dimple portion to increase the number of contacts to an upper spring of the two-bodied spring, so as to increase the stiffness of the two-bodied spring.

Abstract: An electrical female terminal for mating with a connector assembly generally including a main body, a two-bodied spring, and a wire fastening portion. A protrusion extends from an unattached end portion of the lever member, the protrusion having faces angled relative to each other to efficiently deflect the lever member upwards when the protrusion interacts with an internal protrusion of a housing or a connector assembly. A top portion of the retainer member of the electrical female terminal, located above the two-bodied spring, has a dimple portion. The terminal face or leading end portion of the electrical female terminal is prevented from damaging or cutting a silicone seal. The overstress feature of the tang member of the lever is improved upon by relocating and reshaping the protruding member thereof. The configuration or shape of the cross-section across the upper portion and the support member at the front end portion of the main body of the electrical female terminal is substantially U-shaped.

Abstract: An image sensor structure including an image stack disposed over a device stack. The image stack includes a plurality of light detectors. A first optical filter stack is disposed over the image stack. The first optical filter stack includes a light guide layer. Light pipe cavities are disposed in the light guide layer. Each light pipe cavity is associated with a light detector. Each light pipe cavity has an aspect ratio that is greater than about 2.5 to about 1. A nanowell layer is disposed over the first optical filter stack. Nanowells are disposed in the nanowell layer. Each nanowell is associated with a light detector.

Abstract: A method recording in-kind payments from a wireless communication service account. The method comprises building a block-chain associated with a wireless communication service account by an application executing on a computer system, where the block-chain encapsulates logic instructions, building a first block recording a first in-kind payment by the application based on executing the logic instructions encapsulated in the block-chain, where the first block comprises a first plurality of event records, a first nonce value, and a first hash value based on a hash value from a preceding block, on the first plurality of event records, and the first nonce value, and sending an in-kind payment authorization message to a wireless communication service billing system, whereby the first in-kind payment is committed.