Abstract: An example of a flow cell includes a substrate; a plurality of reactive regions extending along the substrate; and a non-reactive region separating one of the plurality of reactive regions from an adjacent one of the plurality of reactive regions. Each of the plurality of reactive regions includes alternating first and second areas positioned along the reactive region. Each of the first areas includes a first primer set and each of the second areas includes a second primer set that is different than the first primer set. Either adjacent first and second areas directly abut each other, or) the first areas are positioned on protrusions and the second areas are positioned in depressions adjacent to the protrusions.

Abstract: A range of technique for investigating a sample such as obtaining images and/or spectral information are described. The techniques include a method for deriving structural information about a sample as a continuous function of the depth below the surface of the sample, a method for evaluating a part of the structure of a sample located between two interfaces within the sample, and a contrast enhancing method and apparatus which has a quick image acquisition time.

Abstract: A user interface system for a device that includes a first deformable layer that with a first sheet that defines a first surface, a first fluid vessel arranged underneath the first surface, and a first volume of fluid contained within the first fluid vessel that is manipulated to deform a first particular region of the first surface to receive a user input; a second deformable layer with a second sheet that defines a second surface, a second fluid vessel arranged underneath the second surface, and a second volume of fluid contained within the second fluid vessel that is manipulated to deform a second particular region of the second surface to change the shape of the device; and a displacement device a displacement device coupled to at least one of the first and second fluid vessels and configured to manipulate the volumes of fluid to deform particular regions of the surface.

Abstract: One embodiment of the user interface system comprises: A tactile layer defining a tactile surface touchable by a user and plurality of deformable regions operable between a retracted state, wherein the deformable regions are flush with an undeformable region of the tactile layer; and an expanded state, wherein the deformable regions are proud of the undeformable region. A substrate joined to the undeformable region and defining a fluid port per deformable region and a fluid channel. A displacement device displacing the fluid through the fluid channel and the fluid ports to transition the deformable regions from the retracted state to the expanded state. A first and a second pressure sensor detecting changes in fluid pressure within the fluid due to a force applied to a particular deformable region. A processor determining the particular deformable region to be location of the input force based upon the detected fluid pressure changes.

Abstract: The user interface system of the preferred embodiments includes a layer defining a tactile surface and including a first region and a particular region adjacent the first region; a substrate defining a fluid channel, cooperating with the layer at the particular region to define a cavity fluidly coupled to the fluid channel, coupled to the layer at the first region; a displacement device displacing fluid into the fluid channel into the cavity to transition the particular region from a retracted volume setting into an expanded volume setting, the particular region substantially level with the first region in the retracted volume setting and elevated above the first region in the expanded volume setting; and a sensor including a first conductor and a second conductor coupled to the substrate and adjacent the cavity, the first conductor offset from the second conductor and capacitively coupled to the second conductor.

Abstract: A user interface system including a sheet that defines a surface and at least partially defines a first level fluid vessel arranged at a first level within the sheet and a second level fluid vessel arranged at a second level within the sheet, wherein both the first and second level fluid vessels are arranged underneath the surface; a first volume of fluid contained within the first level fluid vessel; a second volume of fluid contained within the second level fluid vessel; and a displacement device coupled to the first and second level fluid vessels that selectively manipulates the first and second volumes of fluid, thereby deforming a particular region of the surface to a first and second stage, respectively or deforming a first particular region and a second particular region of the surface, respectively.

Abstract: The user interface system of the preferred embodiments includes a layer defining a tactile surface and including a first region and a particular region adjacent the first region; a substrate defining a fluid channel, cooperating with the layer at the particular region to define a cavity fluidly coupled to the fluid channel, coupled to the layer at the first region; a displacement device displacing fluid into the fluid channel into the cavity to transition the particular region from a retracted volume setting into an expanded volume setting, the particular region substantially level with the first region in the retracted volume setting and elevated above the first region in the expanded volume setting; and a sensor including a first conductor and a second conductor coupled to the substrate and adjacent the cavity, the first conductor offset from the second conductor and capacitively coupled to the second conductor.

Abstract: A user interface system including a sheet that defines a surface and at least partially defines a first level fluid vessel arranged at a first level within the sheet and a second level fluid vessel arranged at a second level within the sheet, wherein both the first and second level fluid vessels are arranged underneath the surface; a first volume of fluid contained within the first level fluid vessel; a second volume of fluid contained within the second level fluid vessel; and a displacement device coupled to the first and second level fluid vessels that selectively manipulates the first and second volumes of fluid, thereby deforming a particular region of the surface to a first and second stage, respectively or deforming a first particular region and a second particular region of the surface, respectively.

Abstract: A user interface system for a device that includes a first deformable layer that with a first sheet that defines a first surface, a first fluid vessel arranged underneath the first surface, and a first volume of fluid contained within the first fluid vessel that is manipulated to deform a first particular region of the first surface to receive a user input; a second deformable layer with a second sheet that defines a second surface, a second fluid vessel arranged underneath the second surface, and a second volume of fluid contained within the second fluid vessel that is manipulated to deform a second particular region of the second surface to change the shape of the device; and a displacement device a displacement device coupled to at least one of the first and second fluid vessels and configured to manipulate the volumes of fluid to deform particular regions of the surface.

Abstract: A user interface system for a device that includes a first deformable layer that with a first sheet that defines a first surface, a first fluid vessel arranged underneath the first surface, and a first volume of fluid contained within the first fluid vessel that is manipulated to deform a first particular region of the first surface to receive a user input; a second deformable layer with a second sheet that defines a second surface, a second fluid vessel arranged underneath the second surface, and a second volume of fluid contained within the second fluid vessel that is manipulated to deform a second particular region of the second surface to change the shape of the device; and a displacement device a displacement device coupled to at least one of the first and second fluid vessels and configured to manipulate the volumes of fluid to deform particular regions of the surface.

Abstract: The user interface system of the preferred embodiment includes: a layer defining a surface, a substrate supporting the layer and at least partially defining a cavity, a displacement device coupled to the cavity and adapted to expand the cavity thereby deforming a particular region of the surface, a touch sensor coupled to the substrate and adapted to sense a user touch proximate the particular region of the surface, and a display coupled to the substrate and adapted to output images to the user. The user interface system of the preferred embodiments has been specifically designed to be incorporated into an electronic device, such as the display of a mobile phone, but may be incorporated in any suitable device that interfaces with a user in both a visual and tactile manner.

Abstract: Disclosed is a user interface system that includes a sheet that defines a surface and at least partially defines a fluid vessel arranged underneath the surface, a volume of fluid within the fluid vessel, a displacement device that influences the volume of the fluid within the fluid vessel to expand and contract at least a portion of the fluid vessel, thereby deforming a particular region of the surface, and a sensor system that is configured to receive a user input on the surface with a first sensitivity and configured to receive a user input substantially proximal to the particular region of the surface at with second sensitivity higher than the first sensitivity.

Abstract: One embodiment of the user interface system comprises: A tactile layer defining a tactile surface touchable by a user and plurality of deformable regions operable between a retracted state, wherein the deformable regions are flush with an undeformable region of the tactile layer; and an expanded state, wherein the deformable regions are proud of the undeformable region. A substrate joined to the undeformable region and defining a fluid port per deformable region and a fluid channel. A displacement device displacing the fluid through the fluid channel and the fluid ports to transition the deformable regions from the retracted state to the expanded state. A first and a second pressure sensor detecting changes in fluid pressure within the fluid due to a force applied to a particular deformable region. A processor determining the particular deformable region to be location of the input force based upon the detected fluid pressure changes.

Abstract: Disclosed is a user interface system that includes a sheet that defines a surface and at least partially defines a fluid vessel arranged underneath the surface, a volume of fluid within the fluid vessel, a displacement device that influences the volume of the fluid within the fluid vessel to expand and contract at least a portion of the fluid vessel, thereby deforming a particular region of the surface, and a sensor system that is configured to receive a user input on the surface with a first sensitivity and configured to receive a user input substantially proximal to the particular region of the surface at with second sensitivity higher than the first sensitivity.

Abstract: A user interface enhancement system that includes a sheet that defines a surface and at least partially defines a fluid vessel arranged underneath the surface, a volume of fluid contained within the fluid vessel that cooperates with the sheet to transmit an image through the sheet without substantial obstruction, a displacement device that influences the volume of fluid within the fluid vessel to expand and retract at least a portion of the fluid vessel, thereby deforming a particular region of the surface, and an attachment component that couples the sheet to the device is disclosed.

Abstract: The user interface system of the preferred embodiment includes: a layer defining a surface, a substrate supporting the layer and at least partially defining a cavity, a displacement device coupled to the cavity and adapted to expand the cavity thereby deforming a particular region of the surface, a touch sensor coupled to the substrate and adapted to sense a user touch proximate the particular region of the surface, and a display coupled to the substrate and adapted to output images to the user. The user interface system of the preferred embodiments has been specifically designed to be incorporated into an electronic device, such as the display of a mobile phone, but may be incorporated in any suitable device that interfaces with a user in both a visual and tactile manner.

Abstract: A user interface enhancement system that includes a sheet that defines a surface and at least partially defines a fluid vessel arranged underneath the surface, a volume of fluid contained within the fluid vessel that cooperates with the sheet to transmit an image through the sheet without substantial obstruction, a displacement device that influences the volume of fluid within the fluid vessel to expand and retract at least a portion of the fluid vessel, thereby deforming a particular region of the surface, and an attachment component that couples the sheet to the device is disclosed.

Abstract: A user interface system including a sheet that defines a surface and at least partially defines a first level fluid vessel arranged at a first level within the sheet and a second level fluid vessel arranged at a second level within the sheet, wherein both the first and second level fluid vessels are arranged underneath the surface; a first volume of fluid contained within the first level fluid vessel; a second volume of fluid contained within the second level fluid vessel; and a displacement device coupled to the first and second level fluid vessels that selectively manipulates the first and second volumes of fluid, thereby deforming a particular region of the surface to a first and second stage, respectively or deforming a first particular region and a second particular region of the surface, respectively.

Abstract: The user interface system of the preferred embodiment includes: a layer defining a surface, a substrate supporting the layer and at least partially defining a cavity, a displacement device coupled to the cavity and adapted to expand the cavity thereby deforming a particular region of the surface, a touch sensor coupled to the substrate and adapted to sense a user touch proximate the particular region of the surface, and a display coupled to the substrate and adapted to output images to the user. The user interface system of the preferred embodiments has been specifically designed to be incorporated into an electronic device, such as the display of a mobile phone, but may be incorporated in any suitable device that interfaces with a user in both a visual and tactile manner.

Abstract: The user interface system of one embodiment of the invention includes a sheet that defines a surface on one side and at least partially defines a first cavity and a second cavity on an opposite side; a fluid network coupled to the first and second cavities; a displacement device coupled to the fluid network that displaces fluid within the fluid network and expands both the first and second cavities concurrently, thereby deforming a first and a second particular region of the surface; and a touch sensor coupled to the sheet and adapted to sense a user touch proximate the first and second particular regions of the surface. The user interface system of another embodiment of the invention includes a displacement device coupled to the fluid network that displaces fluid within the fluid network and selectively expands one of the first and second cavities.