Abstract: A system and method are provided for guiding surgery using MR images and radioactive markers. The method comprises reconstructing the surface of an anatomical structure and a gamma probe orientated to optimize a radioactivity reading from a radioactive seed placed at a target location in the anatomic structure for each of one or more positions of the gamma probe. The position and orientation of the gamma probe is detected in each reconstructed surface to estimate a position of the radioactive seed relative to the reconstructed surface.

Abstract: An image registration apparatus (118) includes an image quality driven image registration determiner (202) that determines an image quality driven image registration for a set of images to register based on a non-rigid registration (204), which includes an optimization of an image similarity term and a regularization term, and a registration steering factor, and a registration component (206) that registers the set of images using the image quality driven image registration. A method determining an image quality driven image registration for a set of images to register based on a non-rigid registration, which includes an optimization of an image similarity term and a regularization term, and a registration steering factor, and registering the set of images using the fidelity driven image registration, generating a set of registered images.

Abstract: An object motion parameter determiner (122) includes a deformation vector field determiner (210) that determines deformation vector fields for a 4D image set, which includes three or more images corresponding to three or more different motion phases of motion of a moving object. The object motion parameter determiner further includes a volume curve determiner (212) that generates a volume curve for the voxel based on the deformation vector fields. The object motion parameter determiner further includes a model fitter (214) that fits a predetermined motion model to the volume curve. The object motion parameter determiner further includes a parameter determiner (218) that estimates at least one object motion parameter based on the fitted model.

Abstract: A system for visualizing an object in image data using a first cross-section surface coupled to a model of the object, the system comprising a model unit for adapting a model to the object in the image data, a surface unit for adapting the first cross-section surface to the adapted model on the basis of the coupling between the first cross-section surface and the model, and a visualization unit for computing an image from the image data on the basis of the adapted first cross-section surface. The first cross-section surface may be used to define a slice of the image data for visualizing useful features of the object. Advantageously, adapting the model to the object in the image data and the coupling between the first cross-section surface and the model enable the first cross-section surface to be adapted to the image data. Thus, the shape, orientation and/or position of the adapted first cross-section surface is/are based on the shape, orientation and/or position of the adapted model.

Abstract: A double focal spot X-ray tube (104) is used to acquire a set of two images PI?, PI? for a given gantry position from slightly different view positions. The stereo or binocular disparity (BD) of imaged structures is used to estimate the object depth in view direction, which in turn is used to discriminate between objects inside IO and outside EO the body. Respective structures are virtually removed from the images PI?, PI?.

Abstract: The invention relates to a system for segmenting an object in image data using model-based image segmentation. The system comprises a feature unit for identifying features in the image data for computing an external energy of a mesh on the basis of a current position of the mesh. The feature unit further comprises a candidate feature unit for selecting a plurality of candidate features in the image data. The feature unit further comprises a position unit for determining a position of each candidate feature of the plurality of the candidate features relative to a region of the image data. The feature unit further comprises a feature function unit for computing a strength of each candidate feature. The feature unit further comprises an evaluation unit for evaluating each candidate feature of the plurality of candidate features and for identifying the feature among the plurality of candidate features based on this evaluation.

Abstract: An imaging method for identifying abnormal tissue in the lung is provided, comprising the recording of slice images of the lung by means of X-ray radiation, recording of blood vessels, differentiation of blood vessels and abnormal tissue, segmentation of the abnormal tissue and display of the segmented abnormal tissue on an output device. In addition, a computer tomograph for identifying abnormal tissue in the lung is provided, having a radiation source for recording slice images of the lung and blood vessels by means of X-ray radiation, a computer unit for differentiating the blood vessels from the abnormal tissue and for segmenting the abnormal tissue, as well as an output device for displaying the segmented abnormal tissue.

Abstract: An imaging method for identifying abnormal tissue in the lung is provided, comprising the recording of slice images of the lung by means of X-ray radiation, recording of blood vessels, differentiation of blood vessels and abnormal tissue, segmentation of the abnormal tissue and display of the segmented abnormal tissue on an output device. In addition, a computer tomograph for identifying abnormal tissue in the lung is provided, having a radiation source for recording slice images of the lung and blood vessels by means of X-ray radiation, a computer unit for differentiating the blood vessels from the abnormal tissue and for segmenting the abnormal tissue, as well as an output device for displaying the segmented abnormal tissue.

Abstract: An apparatus and a method for post processing 2D image slices (110a-c) defining a 3D image volume. The apparatus comprises a graphical user interface controller (160), a 2D segmenter (170) and a 3D segmenter (180). The apparatus allows a user to effect calculation and display of a 2D segmentation of a cross section of an object shown in a slice (110a) and calculation and display of a 3D segmentation of the object across the 3D image volume, the 3D segmentation based on the object's previously calculated 2D segmentation.

Abstract: A system for displaying lung ventilation information, the system comprising an input (12) and a processing unit (15). The input being provided for receiving multiple CT images (71) of a lung, each CT image (71) corresponding to one phase of at least two different phases in a respiratory cycle. The processing unit (15) being configured to compare CT images (71) corresponding to different phases in the respiratory cycle for determining a deformation vector field for each phase, to generate for each phase a ventilation image (72) based on the corresponding deformation vector field, to spatially align the ventilation images (72), and to generate for at least one common position (62) in each one of the aligned ventilation images (72), a function (81) of a time course of a ventilation value for said common position (62), each ventilation value in the function (81) being based on the deformation vector fields corresponding to the aligned ventilation images (73).

Abstract: The invention relates to a respiratory motion determination apparatus for determining respiratory motion of a living being (3). A raw data providing unit (2) provides raw data assigned to different times, wherein the raw data are indicative of a structure like the apex of the heart muscle, which is influenced by cardiac motion and by respiratory motion, and a reconstruction unit (6) reconstructs intermediate images of the structure from the provided raw data. A structure detection unit (7) detects the structure in the reconstructed intermediate images, and a respiratory motion determination unit (10) determines the respiratory motion of the living being based on the structure detected in the reconstructed intermediate images. This allows determining respiratory motion with high accuracy, without relying on, for example, a stable correlation between a tracking signal of an external respiratory gating device and respiratory phases.

Abstract: A system is provided for obtaining a nuclear image of a moving object. The system comprises an input (14), a processing unit (15) and an output (17). The input (14) is provided for receiving a nuclear image and morphological images of the object. The processing unit (15) is configured to process the morphological images to obtain sparse motion information of the object, to use the sparse motion information and a motion model for obtaining estimated motion information about the object, and to generate a motion-corrected nuclear image based on the estimated motion information and the acquired nuclear image. The output (17) provides the corrected nuclear image.

Abstract: The invention relates to a system (100) for segmenting a plurality of objects in image data using simultaneous model-based image segmentation. A surface mesh is adapted to each object to be segmented. To avoid or reduce the possibility of mesh collision, a plurality of connecting edges for connecting two proximal meshes are used. A connection energy defined for the plurality of connecting edges allows controlling the spatial relationship between the first and second mesh. This is achieved by including in the connection energy expression terms that will increase the connection energy when the lengths of edges of the plurality of connecting edges connecting the first and second mesh decrease. Using the reference configuration of the plurality of connecting edges defined based on the pre-positioned first and second mesh allows taking into account prior knowledge about a typical spatial relationship between the first and second object of the plurality of objects.

Abstract: The invention relates to a system (100) for segmenting an object in an image, comprising a first adapter (110) for adapting a first model for segmenting the object to the image, an analyzer (115) for extracting a feature from the image based on the adapted first model, a selector (120) for selecting a second model for segmenting the object from a plurality of models for segmenting the object, based on the feature extracted from the image, wherein the second model comprises additional detail of the object, an initializer (125) for initializing the second model based on the adapted first model and/or the feature extracted from the image, and a second adapter (130) for adapting the initialized second model to the image. The features extracted from the image based on the adapted first model help the system (100) to select the second model for segmenting the object from a plurality of models for segmenting the object.

Abstract: The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.

Abstract: A system for validating motion estimation comprising a field unit (110) for obtaining a deformation vector field (DVF) estimating the motion by transforming a first image at a first phase of the motion into a second image at a second phase of the motion, a metric unit (120) for computing a metric of a local volume change at a plurality of locations, and a conformity unit (130) for computing a conformity measure based on the computed metric of the local volume change at the plurality of locations and a local property of the first or second image defined at the plurality of locations. Based on the value of the conformity measure, the DFV estimating the motion is validated. Experiments show that the conformity measure based on the computed metric of a local volume change at a plurality of locations and the local property of the first or second image, defined at the plurality of locations, does not necessarily favor a large weight for the outer force to provide a more accurate registration.

Abstract: The invention relates to a system (100) for propagating a model mesh based on a first mean model mesh and on a second mean model mesh, the system comprising: a registration unit (110) for computing a registration transformation for registering the first model mesh with the first mean model mesh; a forward transformation unit (120) for transforming the model mesh into a registered model mesh using the registration transformation; a computation unit (130) for computing a propagation field for propagating the registered model mesh, the propagation field comprising vectors of displacements of vertices of the second mean model mesh relative to respective vertices of the first mean model mesh; a propagation unit (140) for transforming the registered model mesh into the propagated registered model mesh based on applying the vertex displacement vectors comprised in the propagation field to respective vertices of the registered model mesh; and an inverse transformation unit (150) for transforming the propagated regist

Abstract: The invention relates to a system for adapting a plurality of model meshes to a plurality of image data. The system has a registration unit for registering the plurality of model meshes with the plurality of image data on the basis of a computation of a registration transformation for transforming the plurality of model meshes, and an adaptation unit for adapting the plurality of registered model meshes to the plurality of image data on the basis of a computation of locations of mesh vertices of the plurality of model meshes. The described system is capable of reducing motion artifacts in tomographic images computed from data acquired at a plurality of different cardiac cycle phases.

Abstract: A system including a display and a processor and a corresponding method for identifying a tumor in a patient image, classifying the tumor based on a predetermined classification system and determining a recommendation regarding a lymph node biopsy based on the tumor identified in the patient image, the classification of the tumor and a predetermined rule.

Abstract: The invention relates to a system (100) for registering a vessel model with an image data set based on a joined model comprising a reference object model and the vessel model, the system comprising: a placement unit (110) for placing the joined model in a space of the image data set, thereby creating a placed joined model comprising a placed reference object model and a placed vessel model; a computation unit (120) for computing a deformation field based on a landmark displacement field comprising displacements of landmarks of the placed reference object model relative to corresponding landmarks in the image data set; a transformation unit (130) for transforming the placed joined model using the deformation field, thereby creating a transformed joined model comprising a transformed reference object model and a transformed vessel model; and a registration unit (140) for registering the transformed vessel model with the image data set based on modifying the transformed vessel model and optimizing an objective f