Patents by Inventor Cynthia A. Maryanoff

Cynthia A. Maryanoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing retinoyl chlorides
    Patent number: 4743400
    Abstract: A process to prepare retinoyl chlorides, e.g., of the following formula (I): ##STR1## under very mild chlorinating conditions by the action of a reagent amount of dimethylchloroformamidinium chloride on a corresponding retinoic acid.
    Type: Grant
    Filed: September 22, 1986
    Date of Patent: May 10, 1988
    Assignee: McNeilab, Inc.
    Inventor: Cynthia A. Maryanoff
  • Methane sulfonic acid derivatives
    Patent number: 4693850
    Abstract: Novel synthetic steps and intermediates leading to guanidines such as the anti-diabetic compound linogliride.
    Type: Grant
    Filed: November 26, 1986
    Date of Patent: September 15, 1987
    Assignee: McNeilab, Inc.
    Inventors: Cynthia A. Maryanoff, James N. Plampin, Robin C. Stanzione
  • Process for producing amidine sulfonic acids
    Patent number: 4656291
    Abstract: An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): ##STR1## with H.sub.2 O.sub.2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps.
    Type: Grant
    Filed: May 28, 1986
    Date of Patent: April 7, 1987
    Assignee: McNeilab, Inc.
    Inventors: Cynthia A. Maryanoff, James N. Plampin, Robin C. Stanzione
  • Process for producing guanidines such as linogliride
    Patent number: 4656270
    Abstract: Novel synthetic steps and intermediates leading to guanidines such as the anti-diabetic compound linogliride.
    Type: Grant
    Filed: March 15, 1985
    Date of Patent: April 7, 1987
    Assignee: McNeilab, Inc.
    Inventors: Cynthia A. Maryanoff, James N. Plampin, Robin C. Stanzione
  • Process for production of methyl 2-tetradecylgycidate
    Patent number: 4499294
    Abstract: An improved process for producing the hypoglycemic compound, methyl 2-tetradecylglycidate, by reacting methyl .alpha.-chloropalmitate with lithium methoxide in the presence of formaldehyde in a dipolar aprotic solvent such as DMF or DMSO.
    Type: Grant
    Filed: January 21, 1983
    Date of Patent: February 12, 1985
    Assignee: McNeilab, Inc.
    Inventor: Cynthia A. Maryanoff