Patents by Inventor Daan Witters

Daan Witters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMPLIFICATION OLIGONUCLEOTIDES
    Publication number: 20230287492
    Abstract: Disclosed herein, inter alia, are polynucleotides, supports, kits, and methods of use thereof for amplifying, immobilizing, and sequencing polynucleotides.
    Type: Application
    Filed: March 17, 2023
    Publication date: September 14, 2023
    Inventors: Ryan SHULTZABERGER, Allen LIPSON, Daan WITTERS
  • AMPLIFICATION OLIGONUCLEOTIDES
    Publication number: 20230287493
    Abstract: Disclosed herein, inter alia, are polynucleotides, supports, kits, and methods of use thereof for amplifying, immobilizing, and sequencing polynucleotides.
    Type: Application
    Filed: March 17, 2023
    Publication date: September 14, 2023
    Inventors: Ryan SHULTZABERGER, Allen LIPSON, Daan WITTERS
  • NUCLEIC ACID DELIVERY SCAFFOLDS
    Publication number: 20230287491
    Abstract: Disclosed herein, inter alia, are degradable nanoparticles, nanoarrays, and methods of use thereof in nucleic acid sequencing.
    Type: Application
    Filed: March 9, 2023
    Publication date: September 14, 2023
    Inventors: Mark Kalaj, Daan Witters
  • Methods and systems and related compositions for mixtures separation with a solid matrix
    Patent number: 11753635
    Abstract: Methods and systems and related compositions for separating through a solid matrix a mixture comprising a nucleic acid together with a target compound having a water solubility equal to or greater than 0.01 mg per 100 mL, which can be used for managing fluid flow, biochemical reactions and purification of the nucleic acid or other target analytes.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: September 12, 2023
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Rustem Ismagilov, Erik Jue, Daan Witters
  • HIGH DENSITY SEQUENCING AND MULTIPLEXED PRIMING
    Publication number: 20230242904
    Abstract: Disclosed herein, inter alia, are methods and compositions for sequencing a plurality of template nucleic acids.
    Type: Application
    Filed: January 13, 2023
    Publication date: August 3, 2023
    Inventors: Eli N. GLEZER, Daan WITTERS, Niek VAN WIETMARSCHEN
  • METHODS AND COMPOSITIONS FOR SEQUENCING COMPLEMENTARY POLYNUCLEOTIDES
    Publication number: 20230227904
    Abstract: Disclosed herein, inter alia, are substrates, kits, and efficient methods of preparing and sequencing two or more regions of a double-stranded polynucleotide.
    Type: Application
    Filed: January 13, 2023
    Publication date: July 20, 2023
    Inventors: Daan WITTERS, Eli N. GLEZER, Allen LIPSON
  • SEQUENCING COMPLEMENTARY POLYNUCLEOTIDES
    Publication number: 20230227905
    Abstract: Disclosed herein, inter alia, are methods for sequencing both strands of a double stranded nucleic acid fragment. Compositions and kits for use in the methods are also provided.
    Type: Application
    Filed: January 20, 2023
    Publication date: July 20, 2023
    Inventors: Andrew KING, Daan WITTERS
  • AMPLIFICATION OLIGONUCLEOTIDES
    Publication number: 20230212664
    Abstract: Disclosed herein, inter alia, are polynucleotides, supports, kits, and methods of use thereof for amplifying, immobilizing, and sequencing polynucleotides.
    Type: Application
    Filed: March 17, 2023
    Publication date: July 6, 2023
    Inventors: Ryan SHULTZABERGER, Allen LIPSON, Daan WITTERS
  • NANOARRAYS AND METHODS OF USE THEREOF
    Publication number: 20230203579
    Abstract: Disclosed herein, inter alia, are nanoarrays and methods of use thereof.
    Type: Application
    Filed: February 17, 2023
    Publication date: June 29, 2023
    Inventors: Eli N. Glezer, Vahid Karimkhani, Shahed Kay, Mohammad Vatankhah Varnosfaderani, Daan Witters
  • LINKED PAIRED STRAND SEQUENCING
    Publication number: 20230203576
    Abstract: Provided herein are methods for sequencing both strands of a double stranded nucleic acid fragment that improves fidelity and accuracy of a sequence determination compared to traditional next generation sequencing methods. Compositions and kits for use in the methods are also provided.
    Type: Application
    Filed: November 17, 2022
    Publication date: June 29, 2023
    Inventors: Eli N. GLEZER, Martin Maria FABANI, Timothy LOONEY, Sabrina SHORE, Ryan SHULTZABERGER, Daan WITTERS
  • METHODS AND COMPOSITIONS FOR SEQUENCING COMPLEMENTARY POLYNUCLEOTIDES
    Publication number: 20230193377
    Abstract: Disclosed herein, inter alia, are substrates, kits, and efficient methods of preparing and sequencing two or more regions of a double-stranded polynucleotide.
    Type: Application
    Filed: October 21, 2022
    Publication date: June 22, 2023
    Inventors: Daan WITTERS, Eli N. GLEZER, Allen LIPSON
  • CHEMICAL AND THERMAL ASSISTED NUCLEIC ACID AMPLIFICATION METHODS
    Publication number: 20230175049
    Abstract: Disclosed herein, inter alia, are novel methods pertaining to nucleic acid amplification and detection. Devices, compositions, and kits for use in such methods are also provided.
    Type: Application
    Filed: January 27, 2023
    Publication date: June 8, 2023
    Inventors: Allen LIPSON, Daan WITTERS, Eli N. GLEZER
  • High density sequencing and multiplexed priming
    Patent number: 11649452
    Abstract: Disclosed herein, inter alia, are methods and compositions for sequencing a plurality of template nucleic acids.
    Type: Grant
    Filed: October 13, 2022
    Date of Patent: May 16, 2023
    Assignee: SINGULAR GENOMICS SYSTEMS, INC.
    Inventors: Eli N. Glezer, Daan Witters, Niek Van Wietmarschen
  • Nanoarrays and methods of use thereof
    Patent number: 11629380
    Abstract: Disclosed herein, inter alia, are nanoarrays and methods of use thereof.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: April 18, 2023
    Assignee: Singular Genomics Systems, Inc.
    Inventors: Eli N. Glezer, Vahid Karimkhani, Shahed Kay, Mohammad Vatankhah Varnosfaderani, Daan Witters
  • HIGH DENSITY SEQUENCING AND MULTIPLEXED PRIMING
    Publication number: 20230111099
    Abstract: Disclosed herein, inter alia, are methods and compositions for sequencing a plurality of template nucleic acids.
    Type: Application
    Filed: October 13, 2022
    Publication date: April 13, 2023
    Inventors: Eli N. GLEZER, Daan WITTERS, Niek VAN WIETMARSCHEN
  • METHODS OF SEQUENCING CIRCULAR TEMPLATE POLYNUCLEOTIDES
    Publication number: 20230095409
    Abstract: Disclosed herein, inter alia, are complexes, kits, and efficient methods of sequencing two strands of a double stranded polynucleotide.
    Type: Application
    Filed: September 22, 2022
    Publication date: March 30, 2023
    Inventors: Daan WITTERS, Allen Lipson, Eli N. Glezer
  • METHODS AND COMPOSITIONS FOR SEQUENCING COMPLEMENTARY POLYNUCLEOTIDES
    Publication number: 20230086385
    Abstract: Disclosed herein, inter alia, are substrates, kits, and efficient methods of preparing and sequencing two or more regions of a double-stranded polynucleotide.
    Type: Application
    Filed: September 22, 2022
    Publication date: March 23, 2023
    Inventors: Daan WITTERS, Eli N. GLEZER, Allen LIPSON
  • High density sequencing and multiplexed priming
    Patent number: 11578320
    Abstract: Disclosed herein, inter alia, are methods and compositions for sequencing a plurality of template nucleic acids.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: February 14, 2023
    Assignee: SINGULAR GENOMICS SYSTEMS, INC.
    Inventors: Eli N. Glezer, Daan Witters, Niek Van Wietmarschen
  • Methods and compositions for sequencing complementary polynucleotides
    Patent number: 11560590
    Abstract: Disclosed herein, inter alia, are substrates, kits, and efficient methods of preparing and sequencing two or more regions of a double-stranded polynucleotide.
    Type: Grant
    Filed: June 14, 2022
    Date of Patent: January 24, 2023
    Assignee: SINGULAR GENOMICS SYSTEMS, INC.
    Inventors: Daan Witters, Eli N. Glezer, Allen Lipson
  • NANOARRAYS AND METHODS OF USE THEREOF
    Publication number: 20220396834
    Abstract: Disclosed herein, inter alia, are nanoarrays and methods of use thereof.
    Type: Application
    Filed: August 5, 2022
    Publication date: December 15, 2022
    Inventors: Eli N. Glezer, Vahid Karimkhani, Shahed Kay, Mohammad Vatankhah Varnosfaderani, Daan Witters