Patents by Inventor Dale Ando

Dale Ando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for gene inactivation
    Publication number: 20100111907
    Abstract: Disclosed herein are methods and compositions for inactivating CCR-5 genes, using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding ZFNs, vectors comprising polynucleotides encoding ZFNs, such as adenovirus (Ad) vectors, and cells comprising polynucleotides encoding ZFNs and/or cells comprising ZFNs are also provided.
    Type: Application
    Filed: October 15, 2009
    Publication date: May 6, 2010
    Inventors: Dale Ando, Michael C. Holmes, Gary Ka Leong Lee
  • Cancer-associated antigens and methods of their identification and use
    Patent number: 7645587
    Abstract: The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.
    Type: Grant
    Filed: May 2, 2007
    Date of Patent: January 12, 2010
    Assignees: BioSante Pharmaceuticals, Inc., John Hopkins University
    Inventors: James McArthur, Ju-Fay Chang, Dale Ando, Margo Roberts, Jonathan Simons, William Nelson
  • Methods and compositions for modification of the human glucocorticoid receptor locus
    Publication number: 20080188000
    Abstract: Disclosed herein are methods and compositions for inactivation of the human glucocorticoid receptor (GR) gene by targeted cleavage of genomic DNA encoding the GR. Such methods and compositions are useful, for example, in therapeutic applications which require retention of immune function during glucocorticoid treatment.
    Type: Application
    Filed: November 13, 2007
    Publication date: August 7, 2008
    Inventors: Andreas Reik, Michael Jensen, Michael C. Holmes, Philip D. Gregory, Dale Ando
  • Methods and compositions for gene inactivation
    Publication number: 20080159996
    Abstract: Disclosed herein are methods and compositions for inactivating CCR-5 genes, using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding ZFNs, vectors comprising polynucleotides encoding ZFNs, such as adenovirus (Ad) vectors, and cells comprising polynucleotides encoding ZFNs and/or cells comprising ZFNs are also provided.
    Type: Application
    Filed: May 23, 2007
    Publication date: July 3, 2008
    Inventors: Dale Ando, Michael C. Holmes, Gary Ka Leong Lee
  • Novel cancer-associated antigens and methods of their identification and use
    Publication number: 20070212739
    Abstract: The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.
    Type: Application
    Filed: May 2, 2007
    Publication date: September 13, 2007
    Applicant: Cell Genesys, Inc.
    Inventors: James McArthur, Ju-Fay Chang, Dale Ando, Margo Roberts, Jonathan Simons, William Nelson
  • Cancer-associated antigens and methods of their identification and use
    Patent number: 7226606
    Abstract: The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.
    Type: Grant
    Filed: November 16, 2005
    Date of Patent: June 5, 2007
    Assignee: Cell Genesys, Inc.
    Inventors: James McArthur, Ju-Fay Chang, Dale Ando, Margo Roberts, Jonathan Simons, William Nelson
  • Cancer-associated antigens and methods of their identification and use
    Patent number: 7217421
    Abstract: The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: May 15, 2007
    Assignee: Cell Genesys, Inc.
    Inventors: James McArthur, Ju-Fay Chang, Dale Ando, Margo Roberts, Jonathan Simons, William Nelson
  • Novel cancer-associated antigens and methods of their identification and use
    Publication number: 20060078544
    Abstract: The present invention provides novel, isolated, tumor-associated antigens, and methods for identifying such antigens in a biological sample, and of screening for the presence of such an antigen in a biological specimen, wherein the tumor antigen identified reacts with serum from a subject treated with a vaccine comprising a cytokine and proliferation-incompetent tumor cells which express the tumor-associated antigen. Also provided are kits for carrying out the methods of the invention.
    Type: Application
    Filed: November 16, 2005
    Publication date: April 13, 2006
    Inventors: James McArthur, Ju-Fay Chang, Dale Ando, Margo Roberts, Jonathan Simons, William Nelson