Abstract: The present invention is directed towards systems and methods for providing classification of an encrypted network packet for performing QoS and acceleration techniques. Encrypted packets may be classified by a first classifier at a first portion of a network stack of a device as corresponding to a first predetermined application, and an application identifier may be included with the packet. In some embodiments, the packets may be decrypted in an order dependent on a first classification of the encrypted network packet. After decryption, packets may be reclassified as corresponding to a second predetermined application by a second classifier operating at a second portion of a network stack of the device above the first portion. Thus, network performance may be enhanced and optimized by providing QoS and acceleration engines with packet- or data-specific information corresponding to the application, while avoiding inefficiencies due to a lack of prioritization of decryption.

Abstract: The present invention is concerned with deuterium-enriched pyrimidine compounds of formula I, their derivatives and pharmaceutically acceptable salts and methods of use thereof for the treatment of pulmonary arterial hypertension, pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD), asthma, cystic fibrosis, hypertension, ischemic stroke, angina pectoris, congestive heart failure, arrhythmia, arterial fibrillation, Alzheimer's disease, cognition impairment, memory decline, and schizophrenia, and depression.

Abstract: The present invention relates to deuterium-enriched pyridinone carboxamides and their derivatives of the formula I, and pharmaceutically acceptable salts thereof, are partial or full agonists of serotonin (5-Hydroxytryptamine or 5-HT4) receptor subtype 4, and are useful compounds for the prevention and treatment of Alzheimer's disease, cognitive and memory dysfunction, mild cognition impairment, memory decline, cognitive impairment associated with schizophrenia, cognitive impairment associated with age-related dementia or Alzheimer's disease, cognitive impairment associated with post-coronary bypass surgery, attention deficit hyperactivity disorder, speech improvement in autistic children, sleep apnea in Alzheimer's patients, irritable bowel syndrome, gastroesophageal reflux disease, Crobn's disease, emesis, nausea, vomiting, prokinesia, non-ulcer dyspepcia, anxiety, depression, pain, migraine, urinary incontinence, arterial fibrillation, arrhythmia, ischemic stroke, gastric emptying disorders, gastritis,

Abstract: The present invention is concerned with deuterium-enriched isobutyl and cyclohexylmethyl sulfonamides of formula I and II, and pharmaceutically acceptable salts and methods of use thereof for the treatment of general anxiety disorders, major depressive disorders, attention deficit disorders, attention deficit hyperactivity disorder, Alzheimer's disease, frontotemporal dementia, cognitive impairment associated with age-related dementia, schizophrenia, migraine, sleep disorders, neurodegenerative diseases and obesity.

Abstract: An anti-vortex device for use in a compressor rotor assembly of a gas turbine engine is described. Spaced-apart radial passageways extend from an axially extending passage provided in a central area of the device to an outer peripheral rim surface thereof. The radial passageways channel air from the primary gaspath about the rotor assembly to the axially extending passage where the air is directed into a central axial passage of the rotor assembly.

Abstract: The present invention is concerned with deuterium-enriched pyrimidine compounds of formula I, their derivatives, enantiomers, diastereomers, solvates and pharmaceutical salts thereof, and their uses in the treatment, prevention and modulation of various diseases including chronic liver diseases, liver cirrhosis, liver fibrosis, hepatocellular carcinoma, liver cancer, renal cell carcinoma, kidney cancer, colorectal cancer, brain cancer, breast cancer, blood cancer, lung cancer, thyroid cancer, ovarian cancer, pancreas cancer, prostate cancer, stomach cancer, testicular cancer, uterus cancer, intestinal cancer, skin cancer, and other forms of cancer, carcinoid tumors, teratocarcinoma, tumor progression, metastasis and fibrosis in the neuroendocrine neoplasia, fibrotic processes as well as a disease state modulated directly or indirectly with 5-HT receptors, 5-HT1, 5-HT1A, 5-HT2 receptors, 5-HT2A and 5-HT2B receptors, dopamine receptors and multiple kinase pathways.

Abstract: The present invention is directed towards systems and methods for providing discovery of applications for classification of a network packet for performing QoS and acceleration techniques. Remote display protocol traffic associated with a new application not previously included in a list of predetermined applications may be parsed for application information, and the new application may be added to the application list. The remote display protocol traffic may then be classified according to the new application, and network performance may be enhanced and optimized by providing QoS and acceleration engines with packet- or data-specific information corresponding to the newly identified application.

Abstract: The present invention is directed towards systems and methods for providing classification of an encrypted network packet for performing QoS and acceleration techniques. Encrypted packets may be classified by a first classifier at a first portion of a network stack of a device as corresponding to a first predetermined application, and an application identifier may be included with the packet. In some embodiments, the packets may be decrypted in an order dependent on a first classification of the encrypted network packet. After decryption, packets may be reclassified as corresponding to a second predetermined application by a second classifier operating at a second portion of a network stack of the device above the first portion. Thus, network performance may be enhanced and optimized by providing QoS and acceleration engines with packet- or data-specific information corresponding to the application, while avoiding inefficiencies due to a lack of prioritization of decryption.

Abstract: The present invention is directed towards systems and methods for providing multi-level classification of a network packet. In some embodiments, network performance may be enhanced and optimized by providing QoS and acceleration engines with packet- or data-specific information. In addition to source and destination IP addresses and port numbers, packet- or data-specific information can include direction of traffic (client to host or server; server or host to client; or both), Virtual LAN (VLAN) ID, source or destination application or associated application, service class, ICA priority, type of service, differentiated service code point (DSCP), or other information. Some or all of this information may be used to classify the network packet at a plurality of layers of a network stack, allowing for deep inspection of the packet and multiple levels of granularity of classification.

Abstract: The present invention is concerned with deuterium-enriched pyrimidine compounds of formula I, their derivatives and pharmaceutically acceptable salts and methods of use thereof for the prevention and treatment of cancer including brain cancer, breast cancer, blood cancer, colorectal cancer, lung cancer, liver cancer, ovarian cancer, pancreas cancer, prostate cancer, stomach cancer, testicular cancer, uterus cancer, intestinal cancer, skin cancer, and other forms of cancer; tumor progression, metastasis and fibrosis in the neuroendocrine neoplasia, fibrotic processes associated with neuroendocrine cell dysregulation for example Crohn's disease, pulmonary arterial hypertension, pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD), right ventricular hypertrophy, pulmonary vascular remodeling, asthma, cystic fibrosis, hypertension, ischemic stroke, angina pectoris, congestive heart failure, arrhythmia, arterial fibrillation, neurodenerative diseases, Alzheimer's disease, dementi

Abstract: The present invention is concerned with deuterium-enriched isobutyl and cyclohexylmethyl sulfonamides of formula I and II, and pharmaceutically acceptable salts and methods of use thereof for the treatment of general anxiety disorders, major depressive disorders, attention deficit disorders, attention deficit hyperactivity disorder, Alzheimer's disease, frontotemporal dementia, cognitive impairment associated with age-related dementia, schizophrenia, migraine, sleep disorders, neurodegenerative diseases and obesity.

Abstract: The present invention is concerned with deuterium-enriched pyrimidine compounds of formula I, their derivatives and pharmaceutically acceptable salts and methods of use thereof for the treatment of pulmonary arterial hypertension, pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD), asthma, cystic fibrosis, hypertension, ischemic stroke, angina pectoris, congestive heart failure, arrhythmia, arterial fibrillation, Alzheimer's disease, cognition impairment, memory decline, and schizophrenia, and depression.

Abstract: The present invention relates to deuterium-enriched pyridinone carboxamides and their derivatives of the formula I, and pharmaceutically acceptable salts thereof, are partial or full agonists of serotonin (5-Hydroxytryptamine or 5-HT4) receptor subtype 4, and are useful compounds for the prevention and treatment of Alzheimer's disease, cognitive and memory dysfunction, mild cognition impairment, memory decline, cognitive impairment associated with schizophrenia, cognitive impairment associated with age-related dementia or Alzheimer's disease, cognitive impairment associated with post-coronary bypass surgery, attention deficit hyperactivity disorder, speech improvement in autistic children, sleep apnea in Alzheimer's patients, irritable bowel syndrome, gastroesophageal reflux disease, Crobn's disease, emesis, nausea, vomiting, prokinesia, non-ulcer dyspepcia, anxiety, depression, pain, migraine, urinary incontinence, arterial fibrillation, arrhythmia, ischemic stroke, gastric emptying disorders, gastritis,

Abstract: An anti-vortex device for use in a compressor rotor assembly of a gas turbine engine is described. Spaced-apart radial passageways extend from an axially extending passage provided in a central area of the device to an outer peripheral rim surface thereof. The radial passageways channel air from the primary gaspath about the rotor assembly to the axially extending passage where the air is directed into a central axial passage of the rotor assembly.

Abstract: A container or vial (1) for a fluid, the container (1) comprising a casing defining an interior for storage of the fluid and a closure member (2). The closure member (2) comprises a body and at least one resilient projection (7) to seal in a storage condition an outlet of the casing, wherein upon an increase in the pressure of the interior of the container (1) the at least one resilient projection (7) is deflected to accommodate outflow of fluid through the outlet. The pressure in the interior of the container (1) may be increased by displacing the closure member (2) into the container (1) or by displacing some other element such as a bung (61, 82) into the container (1). The container (1) and closure member (2) may be used in a dispenser (90) and the closure element may be used in a valve (110).

Abstract: The present invention provides a beverage bottle comprising an outer bottle (2) and an inner container (4). The inner container holds a first liquid (such an alcoholic spirit or a flavoured concentrate) and the space between the outer container and the inner container holds a second liquid (such as a still or carbonated mixer). The inner container (4) is twisted along its length to resist the flow of the first liquid to ensure that if the contents are consumed directly from the beverage bottle, every mouthful contains substantially the same ratio of first and second liquids.

Abstract: An exhaust driven turbofan to operates a generator, for generating electrical energy, which is stored in a battery until needed. An air blower is powered by energy from the battery, to generate pressurized air. The pressurized air passes into the piston chamber when the gas pedal is depressed, independent of the rotation of the crank shaft. An exhaust blower powered by the battery, sucks air from the piston chamber during the exhaust stroke, ensuring complete removal of the exhaust gasses. Valve overlap timing is no longer needed, eliminating the dwell time between intake and exhaust gasses. A non-ferrous wheel having ferrous portions is anchored in spaced relation about the outer periphery of the non-ferrous wheel, to assist the rotation of the crank shaft. At least one electromagnet is selectively energized to aid rotation of the non ferrous wheel.

Abstract: The invention relates to a method of creating a casing in a borehole formed in an underground formation. The method comprises the steps of (a) installing a tubular liner in the borehole, the liner being radially expandable in the borehole whereby the liner in its radially expanded position has a plurality of openings which are overlapping in the longitudinal direction of the liner, (b) radially expanding the liner in the borehole, and (c) either before or after step (b), installing a body of hardenable fluidic sealing material in the borehole so that the sealing material fills said openings and thereby substantially closes said openings. The sealing material is selected so as to harden in said openings and thereby to increase the compressive strength of the liner.

Abstract: Highly reliable and consistent starting is achieved by first initializing the rotor position, namely establishing the rotor in a known starting position. This is accomplished by gating on two pairs of SCRs in sequence and supplying current pulses through the gated SCRs to the stator of the motor to rotate the rotor to a first position and then to a second position, the rotor coming to a complete stop in each of those positions. The rotor aligns itself with the magnetic field created by the stator in each position and any ambiguity in the rotor position is eliminated. Thereafter, the inverter is operated asynchronously in a second mode with predetermined pairs of the inverter SCRs being sequentially gated into conduction at an increasing frequency to current pulse energize the motor to effect step-by-step rotation of the rotor at a faster and faster rate, the motor current being reduced to zero at the termination of each energizing pulse to force commutate the conducting pair of SCRs.

Abstract: In order to produce an optical cable core composed of a plurality of optical cable elements stranded together, each element is produced by longitudinally slitting a stable tube, inserting at least one optical fiber into the tube through the slit, and causing the slit to close behind the fiber so that the fiber lies loosely in the tube, and the resulting elements are then stranded together to form the core.