Patents by Inventor Dandan Liu

Dandan Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12210584
    Abstract: An ecological flow determination method for considering a lifting amount a belongs to a technical field of environmental engineering and includes the following steps: collecting, by a collecting device, data needed to calculate an ecological flow; determining, by a calculating device, an ecological base flow; selecting an upper limit and a lower limit of the ecological base flow so as to determine a range of the ecological base flow; verifying the lower limit of the ecological base flow; calculating water demands of landscape wetland, sediment discharge and dilution self purification of three service objects; comparing the water demands of the three service objects so as to determine the lifting amount, and finding out a minimum value and a maximum value to determine a lower limit and an upper limit of the lifting amount in the range; combining the ecological base flow and the lifting amount to determine the ecological flow.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: January 28, 2025
    Assignee: Xi'an University of Technology
    Inventors: Jungang Luo, Dandan Liu
  • Publication number: 20250019726
    Abstract: The invention is directed to a process to convert carbon dioxide to methane by contacting an aqueous solution comprising dissolved carbon dioxide with an electron charged packed bed comprising of a carrier and a biofilm of microorganisms under anaerobic conditions wherein the pH of the aqueous solution is above 7.5 and wherein the aqueous solution comprises between 0.3 and 4 M sodium cations or between 0.3 and 4 M sodium and potassium cations and more than 20 mM phosphate ions.
    Type: Application
    Filed: November 24, 2022
    Publication date: January 16, 2025
    Applicant: PAQELL B.V.
    Inventors: Dandan LIU, Frederikus DE RINK, Johannes Bernardus Maria KLOK
  • Publication number: 20240309087
    Abstract: An antibody specifically binding to CD112R or an antigen binding fragment thereof, a composition comprising same, a nucleic acid molecule encoding the antibody or the antigen binding fragment thereof, a vector and a host cell for expressing the antibody or the antigen binding fragment thereof, a treatment and diagnostic method using the antibody or the antigen binding fragment thereof, and use of the antibody or the antigen binding fragment thereof.
    Type: Application
    Filed: February 8, 2022
    Publication date: September 19, 2024
    Applicants: SHANGHAI JUNSHI BIOSCIENCES CO., LTD., SUZHOU JUNMENG BIOSCIENCES CO., LTD.
    Inventors: Dandan LIU, Jing ZHANG, Yuehua ZHOU, Jian YAO, Qiang ZHAO, Hui LIU, Hui FENG
  • Publication number: 20240117043
    Abstract: The present disclosure provides a bispecific antibody including a binding domain that binds to CD112R and a binding domain that binds to TIGIT, and the binding domain that binds to CD112R includes: HCDR1, HCDR2 and HCDR3 of the amino acid sequence set forth in SEQ ID NO: 1, and/or LCDR1, LCDR2 and LCDR3 of the amino acid sequence set forth in SEQ ID NO: 2; and the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 are defined according to the Kabat, IMGT, Chothia, AbM or Contact numbering system. The present disclosure further provides a polynucleotide encoding the antibody, an expression vector, a host cell and a method for expressing and purifying the antibody, a pharmaceutical composition including the antibody of the present disclosure, and use of the bispecific antibody for treating cancer.
    Type: Application
    Filed: August 4, 2023
    Publication date: April 11, 2024
    Applicants: SHANGHAI JUNSHI BIOSCIENCES CO., LTD., SUZHOU JUNMENG BIOSCIENCES CO., LTD.
    Inventors: Dandan LIU, Jinwei ZHOU, Yuehua ZHOU, Jing ZHANG, Sheng YAO, Hui FENG, Hui LIU, Hongchuan LIU, Li LI, Qiang ZHAO
  • Publication number: 20230287462
    Abstract: The invention is directed to a process to convert carbon dioxide to methane by contacting an aqueous solution comprising dissolved carbon dioxide with an electron charged packed bed comprising of a carrier, suitably activated carbon granules, and a biofilm of microorganisms under anaerobic conditions, wherein more than 90 mol % of the dissolved carbon dioxide in the aqueous solution is present as a bicarbonate ion and/or as a carbonate ion.
    Type: Application
    Filed: October 13, 2021
    Publication date: September 14, 2023
    Applicant: PAQELL B.V.
    Inventors: Dandan LIU, Frederikus DE RINK, Johannes Bernardus Maria KLOK
  • Patent number: 11655296
    Abstract: The present invention relates to novel antibodies and antibody fragments thereof that specifically bind to integrin-associated proteins (IAP, or CD47), and a composition comprising the antibodies or the antibody fragments. The present invention also relates to a nucleic acid encoding the antibodies or the antibody fragments thereof, a host cell comprising the nucleic acid, and related use. Furthermore, the present invention also relates to therapeutic and diagnostic use of the antibodies and the antibody fragments.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: May 23, 2023
    Assignee: INNOVENT BIOLOGICS (SUZHOU) CO., LTD.
    Inventors: Dandan Liu, Weifeng Huang, Bingliang Chen, Junjian Liu
  • Patent number: 11292836
    Abstract: The present invention is directed to a novel antibody against CD47 and the antibody fragments thereof and a composition comprising the antibody or antibody fragments thereof. The present invention relates further to a nucleic acid encoding the antibodies or antibody fragments thereof and host cells comprise the same, as well as the relevant use of the same. In addition, the present invention is also directed to the use of these antibodies and antibody fragments in the therapy and diagnosis.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: April 5, 2022
    Assignee: INNOVENT BIOLOGICS (SUZHOU) CO., LTD.
    Inventors: Andy Tsun, Dandan Liu, Bingliang Chen, Junjian Liu
  • Publication number: 20210326408
    Abstract: An ecological flow determination method for considering a lifting amount a belongs to a technical field of environmental engineering and includes the following steps: collecting, by a collecting device, data needed to calculate an ecological flow; determining, by a calculating device, an ecological base flow; selecting an upper limit and a lower limit of the ecological base flow so as to determine a range of the ecological base flow; verifying the lower limit of the ecological base flow; calculating water demands of landscape wetland, sediment discharge and dilution self purification of three service objects; comparing the water demands of the three service objects so as to determine the lifting amount, and finding out a minimum value and a maximum value to determine a lower limit and an upper limit of the lifting amount in the range; combining the ecological base flow and the lifting amount to determine the ecological flow.
    Type: Application
    Filed: June 29, 2021
    Publication date: October 21, 2021
    Inventors: Jungang Luo, Dandan Liu
  • Patent number: 11031455
    Abstract: The OLED tiled display includes front and back lighting display units that emitting lights toward each other. The front lighting display unit includes a first substrate and a first organic light emitting device. The back lighting display unit includes a second substrate and a second organic light emitting device. The first and second light emitting devices neighbor laterally on each other, but are vertically aligned to a second extended section of the second substrate and a first extended section of the first substrate, respectively. The present invention achieves small gaps and resolves the problem of obvious gaps in an OLED tiled display by piecing together the front and back lighting display units, where the substrate of the front lighting display unit functions as encapsulation layer to the back lighting display unit, and the substrate of the back lighting display unit functions as encapsulation layer to the front lighting display unit.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: June 8, 2021
    Assignee: WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.
    Inventors: Yuejun Tang, Yang Chen, Dandan Liu, Xiaohui Jiang, Tsungying Yang, Dejiun Li
  • Publication number: 20210083040
    Abstract: The OLED tiled display includes front and back lighting display units that emitting lights toward each other. The front lighting display unit includes a first substrate and a first organic light emitting device. The back lighting display unit includes a second substrate and a second organic light emitting device. The first and second light emitting devices neighbor laterally on each other, but are vertically aligned to a second extended section of the second substrate and a first extended section of the first substrate, respectively. The present invention achieves small gaps and resolves the problem of obvious gaps in an OLED tiled display by piecing together the front and back lighting display units, where the substrate of the front lighting display unit functions as encapsulation layer to the back lighting display unit, and the substrate of the back lighting display unit functions as encapsulation layer to the front lighting display unit.
    Type: Application
    Filed: April 4, 2018
    Publication date: March 18, 2021
    Inventors: Yuejun TANG, Yang CHEN, Dandan LIU, Xiaohui JIANG, Tsungying YANG, Dejiun LI
  • Publication number: 20200377593
    Abstract: The present invention relates to novel antibodies and antibody fragments thereof that specifically bind to integrin-associated proteins (IAP, or CD47), and a composition comprising the antibodies or the antibody fragments. The present invention also relates to a nucleic acid encoding the antibodies or the antibody fragments thereof, a host cell comprising the nucleic acid, and related use. Furthermore, the present invention also relates to therapeutic and diagnostic use of the antibodies and the antibody fragments.
    Type: Application
    Filed: March 26, 2019
    Publication date: December 3, 2020
    Inventors: Dandan LIU, Weifeng HUANG, Bingliang CHEN, Junjian LIU
  • Patent number: 10682421
    Abstract: There is disclosed a composition in the form of a nanoparticle. The nanoparticle composition has a diameter from 5 to 500 nanometers. The nanoparticle composition has i) a central core portion including magnetic Fe3O4 nanoparticles adapted to act as a heat source when subjected to a magnetic field and a chemotherapeutic agent configured to treat cancer tissues, ii)—a shell portion including a shell member encapsulating said core portion, and iii)—antibodies configured to target cancer stem cells and adhered to surface of said shell member. The chemotherapeutic agent is a heat shock protein inhibitor and is releasable on activation of the heat source due to the magnetic field, and the shell member is made of silica or a silica based material.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: June 16, 2020
    Assignee: CITY UNIVERSITY OF HONG KONG
    Inventors: Mengsu Yang, Dandan Liu
  • Publication number: 20200181259
    Abstract: The present invention is directed to a novel antibody against CD47 and the antibody fragments thereof and a composition comprising the antibody or antibody fragments thereof. The present invention relates further to a nucleic acid encoding the antibodies or antibody fragments thereof and host cells comprise the same, as well as the relevant use of the same. In addition, the present invention is also directed to the use of these antibodies and antibody fragments in the therapy and diagnosis.
    Type: Application
    Filed: August 28, 2018
    Publication date: June 11, 2020
    Inventors: Andy TSUN, Dandan LIU, Bingliang CHEN, Junjian LIU
  • Publication number: 20200035196
    Abstract: A method for adjusting a luminance of a RGBW liquid crystal display is provided by the disclosure. The liquid crystal display includes a RGBW sub-pixel, wherein the luminance of the W sub-pixel is achieved by adjusting one or more of width, spacing, thickness of liquid crystal cell, and number of branch of a sub-pixel electrode corresponding to the W sub-pixel, channel region at the sub-pixel electrode corresponding to the W sub-pixel, and aperture ratio at the sub-pixel electrode corresponding to the W sub-pixel. A liquid crystal display is also provided by the disclosure, and the method for adjusting the luminance of the RGBW liquid crystal display is applicable for the luminance of the W sub-pixel for achieving the adjustment of the luminance of the W sub-pixel.
    Type: Application
    Filed: December 14, 2017
    Publication date: January 30, 2020
    Inventors: Yuejun TANG, Yang CHEN, Xiaohui JIANG, Dandan LIU
  • Patent number: 10416503
    Abstract: A blue phase liquid crystal display module and device, and a method for manufacturing the same are disclosed. The module includes an upper substrate, a lower substrate disposed oppositely, multiple blue phase liquid crystal molecules disposed between the upper substrate and the lower substrate, multiple upper common electrodes disposed in parallel and spaced at intervals on the upper substrate, multiple lower common electrodes disposed in parallel and spaced at intervals on the lower substrate, wherein the lower common electrodes are staggered with the upper common electrodes, and a pixel electrode disposed on the lower substrate, wherein, the pixel electrode is a hollow concave-convex structure, the pixel electrode has alternating projections and depressions such that multiple oblique electric fields are generated among the pixel electrode, the upper common electrodes and the lower common electrodes in order to drive the blue phase liquid crystal molecules.
    Type: Grant
    Filed: April 3, 2018
    Date of Patent: September 17, 2019
    Assignee: Wuhan China Star Optoelectronics Technology Co., Ltd
    Inventors: Yuejun Tang, Hongqing Cui, De-Jiun Li, Haiyan Sun, Dandan Liu
  • Publication number: 20180224703
    Abstract: A blue phase liquid crystal display module and device, and a method for manufacturing the same are disclosed. The module includes an upper substrate, a lower substrate disposed oppositely, multiple blue phase liquid crystal molecules disposed between the upper substrate and the lower substrate, multiple upper common electrodes disposed in parallel and spaced at intervals on the upper substrate, multiple lower common electrodes disposed in parallel and spaced at intervals on the lower substrate, wherein the lower common electrodes are staggered with the upper common electrodes, and a pixel electrode disposed on the lower substrate, wherein, the pixel electrode is a hollow concave-convex structure, the pixel electrode has alternating projections and depressions such that multiple oblique electric fields are generated among the pixel electrode, the upper common electrodes and the lower common electrodes in order to drive the blue phase liquid crystal molecules.
    Type: Application
    Filed: April 3, 2018
    Publication date: August 9, 2018
    Applicant: Wuhan China Star Optoelectronics Technology Co., Ltd.
    Inventors: Yuejun TANG, Hongqing CUI, De-Jiun LI, Haiyan SUN, Dandan LIU
  • Publication number: 20180193485
    Abstract: There is disclosed a composition in the form of a nanoparticle. The nanoparticle composition has a diameter from 5 to 500 nanometers. The nanoparticle composition has i) a central core portion including magnetic Fe3O4 nanoparticles adapted to act as a heat source when subjected to a magnetic field and a chemotherapeutic agent configured to treat cancer tissues, ii)—a shell portion including a shell member encapsulating said core portion, and iii)—antibodies configured to target cancer stem cells and adhered to surface of said shell member. The chemotherapeutic agent is a heat shock protein inhibitor and is releasable on activation of the heat source due to the magnetic field, and the shell member is made of silica or a silica based material.
    Type: Application
    Filed: March 8, 2018
    Publication date: July 12, 2018
    Applicant: City University of Hong Kong
    Inventors: Mengsu YANG, Dandan LIU
  • Patent number: 10012860
    Abstract: A polarizer includes a polarizer base and a plurality of protrusive microstructures being arranged on the polarizer base. The microstructure includes at least two layers of curing-light or thermosetting resin materials. The manufacturing method of the curing-light or thermosetting resin materials includes: providing a polarizer base and coating at least two layers of curing-light or thermosetting resin materials on the polarizer base; and arranging a plurality of lighting dots or heating dots on the curing-light or thermosetting resin materials such that the curing-light or thermosetting resin materials shrink and the lighting dots or heating dots are centers of the shrinkage to form a plurality of protrusive microstructures. In addition, a liquid crystal panel includes the above-mentioned polarizer.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: July 3, 2018
    Assignee: Shenzhen China Star Optoelectronics Technology Co., Ltd
    Inventors: Dandan Liu, Dejiun Li
  • Patent number: 10000047
    Abstract: The present invention provides a method for manufacturing a curved liquid crystal display panel, which comprises coating a sealing gum on a first or a second frame sealing region; filing liquid crystals between the two substrates and adhering the two substrates together; performing a first curing on partial sealing gum on a first set or a third set of frame bodies; bending the first set and the third set of frame bodies obtained after the first curing along the extension direction of the first set of frame bodies; performing a second curing on uncured sealing gum on the two bended substrates.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: June 19, 2018
    Assignee: WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO. LTD.
    Inventors: Haiyan Sun, Dejiun Li, Tsungying Yang, Dandan Liu
  • Patent number: 9964813
    Abstract: A blue phase liquid crystal display module and device, and a method for manufacturing the same are disclosed. The module includes an upper substrate, a lower substrate disposed oppositely, multiple blue phase liquid crystal molecules disposed between the upper substrate and the lower substrate, multiple upper common electrodes disposed in parallel and spaced at intervals on the upper substrate, multiple lower common electrodes disposed in parallel and spaced at intervals on the lower substrate, wherein the lower common electrodes are staggered with the upper common electrodes, and a pixel electrode disposed on the lower substrate, wherein, the pixel electrode is a hollow concave-convex structure, the pixel electrode has alternating projections and depressions such that multiple oblique electric fields are generated among the pixel electrode, the upper common electrodes and the lower common electrodes in order to drive the blue phase liquid crystal molecules.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: May 8, 2018
    Assignee: Wuhan China Star Optoelectronics Technology Co., Ltd.
    Inventors: Yuejun Tang, Hongqing Cui, De-Jiun Li, Haiyan Sun, Dandan Liu