Patents by Inventor Dan Kramer

Dan Kramer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9862974
    Abstract: A genetically enhanced cyanobacterial host cell, Cyanobacterium sp. ABICyanoI, is disclosed. The enhanced Cyanobacterium sp. ABICyanoI produces a compound or compounds of interest.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: January 9, 2018
    Assignee: Algenol Biotech LLC
    Inventors: Kui Wang, Tuo Shi, Irina Piven, Masami Inaba, Frank Uliczka, Dan Kramer, Heike Enke, Kerstin Baier, Alexandra Friedrich, Ulf Duehring
  • Patent number: 9765364
    Abstract: This invention provides a method for the prolonged production of ethanol using a metabolically enhanced cyanobacterium.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: September 19, 2017
    Assignee: Algenol Biotech LLC
    Inventors: Ulf Dühring, Alexandra Friedrich, Kerstin Baier, Heike Enke, Dan Kramer
  • Publication number: 20170175148
    Abstract: A non-naturally occurring cyanobacterial cell for the production of a chemical compound of interest is provided which contains at least one genetic modification that alters expression of at least one phosphate uptake regulating gene encoding a protein involved in regulation of phosphate metabolism, so that cellular uptake and/or intracellular storage of a phosphate compound is increased in comparison to a native form of the cyanobacterial cell. Related methods and uses involving the cyanobacterial cell are also provided.
    Type: Application
    Filed: December 22, 2016
    Publication date: June 22, 2017
    Applicant: Algenol Biotech LLC
    Inventors: Dan Kramer, Christian Weissert, John Coleman, Heike Enke, Eva Schunder, Charles Ryan Budinoff, William Patrick Porubsky, Laura Belicka
  • Patent number: 9650642
    Abstract: The invention provides novel compositions of matter for the production of ethanol from carbon dioxide and water. Particularly, the invention provides photoautotrophic organisms having a first and second genetic modification, wherein the first genetic modification improves the ethanol production from organisms having the second genetic modification.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: May 16, 2017
    Assignee: Algenol Biotech LLC
    Inventors: R. Paul Woods, Craig R. Smith, Dan Kramer, Heike Enke, Ulf Duhring, Kerstin Baier, Marianne Grundel, Wolfgang Lockau, Karl Ziegler, Christine Oesterhelt, John Coleman
  • Publication number: 20160265004
    Abstract: This invention provides a method for the prolonged production of ethanol using a metabolically enhanced cyanobacterium.
    Type: Application
    Filed: April 14, 2016
    Publication date: September 15, 2016
    Applicant: Algenol Biotech LLC
    Inventors: Ulf DÜHRING, Alexandra FRIEDRICH, Kerstin BAIER, Heike ENKE, Dan KRAMER
  • Patent number: 9315820
    Abstract: This invention provides a metabolically enhanced cyanobacterium for the production of a chemical compound of interest, having at least two first production genes encoding first biocatalysts for the production of the first chemical compound. One of the two first production genes is under the transcriptional control of a first promoter for the first production gene, whereas the other of the two first production genes is under the transcriptional control of a second promoter for the first production gene. The first promoter and second promoter are separately inducible under different conditions and the at least two first biocatalysts catalyze the same chemical reaction. Metabolically enhanced cyanobacteria according to the present invention allow prolonged production of first chemical compounds.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: April 19, 2016
    Assignee: Algenol Biotech LLC
    Inventors: Ulf Dühring, Alexandra Friedrich, Kerstin Baier, Heike Enke, Dan Kramer
  • Patent number: 9315832
    Abstract: A cyanobacterial host cell, Cyanobacterium sp., that harbors at least one recombinant gene for the production of a chemical compounds is provided, as well as vectors derived from an endogenous plasmid isolated from the cell.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: April 19, 2016
    Assignee: Algenol Biotech LLC
    Inventors: Irina Piven, Alexandra Friedrich, Ulf Dühring, Frank Uliczka, Kerstin Baier, Masami Inaba, Tuo Shi, Kui Wang, Heike Enke, Dan Kramer
  • Publication number: 20160053284
    Abstract: A genetically enhanced cyanobacterial host cell, Cyanobacterium sp. ABICyanoI, is disclosed. The enhanced Cyanobacterium sp. ABICyanoI produces a compound or compounds of interest.
    Type: Application
    Filed: December 23, 2013
    Publication date: February 25, 2016
    Inventors: Kui WANG, Tuo SHI, Irina PIVEN, Masami INABA, Frank ULICZKA, Dan KRAMER, Heike ENKE, Kerstin BAIER, Alexandra FRIEDRICH, Ulf DUEHRING
  • Patent number: 9157101
    Abstract: A genetically enhanced cyanobacterial host cell, Cyanobacterium sp. ABICyano1, is disclosed. The enhanced Cyanobacterium sp. ABICyano1 produces a compound or compounds of interest.
    Type: Grant
    Filed: December 22, 2013
    Date of Patent: October 13, 2015
    Assignee: Algenol Biotech LLC
    Inventors: Irina Piven, Alexandra Friedrich, Ulf Dühring, Frank Uliczka, Kerstin Baier, Masami Inaba, Tuo Shi, Kui Wang, Heike Enke, Dan Kramer
  • Publication number: 20150017704
    Abstract: A cyanobacterial host cell, Cyanobacterium sp., that harbors at least one recombinant gene for the production of a chemical compounds is provided, as well as vectors derived from an endogenous plasmid isolated from the cell.
    Type: Application
    Filed: June 5, 2014
    Publication date: January 15, 2015
    Applicant: ALGENOL BIOFUELS INC.
    Inventors: Irina Piven, Alexandra Friedrich, Ulf Dühring, Frank Uliczka, Kerstin Baier, Masami Inaba, Tuo Shi, Kui Wang, Heike Enke, Dan Kramer
  • Publication number: 20140322799
    Abstract: This invention provides a metabolically enhanced cyanobacterium for the production of a chemical compound of interest, having at least two first production genes encoding first biocatalysts for the production of the first chemical compound. One of the two first production genes is under the transcriptional control of a first promoter for the first production gene, whereas the other of the two first production genes is under the transcriptional control of a second promoter for the first production gene. The first promoter and second promoter are separately inducible under different conditions and the at least two first biocatalysts catalyze the same chemical reaction. Metabolically enhanced cyanobacteria according to the present invention allow prolonged production of first chemical compounds.
    Type: Application
    Filed: June 30, 2014
    Publication date: October 30, 2014
    Applicant: Algenol Biofuels Inc.
    Inventors: Ulf Dühring, Alexandra FRIEDRICH, Kerstin BAIER, Heike ENKE, Dan KRAMER
  • Patent number: 8846369
    Abstract: A cyanobacterial host cell, Cyanobacterium sp., that harbors at least one recombinant gene for the production of a chemical compounds is provided, as well as vectors derived from an endogenous plasmid isolated from the cell.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: September 30, 2014
    Assignee: Algenol Biofuels Inc.
    Inventors: Irina Piven, Alexandra Friedrich, Ulf Dühring, Frank Uliczka, Kerstin Baier, Masami Inaba, Tuo Shi, Kui Wang, Heike Enke, Dan Kramer
  • Publication number: 20140178973
    Abstract: A cyanobacterial host cell, Cyanobacterium sp., that harbors at least one recombinant gene for the production of a chemical compounds is provided, as well as vectors derived from an endogenous plasmid isolated from the cell.
    Type: Application
    Filed: September 30, 2013
    Publication date: June 26, 2014
    Applicant: ALGENOL BIOFUELS INC.
    Inventors: Irina Piven, Alexandra Friedrich, Ulf Dühring, Frank Uliczka, Kerstin Baier, Masami Inaba, Tuo Shi, Kui Wang, Heike Enke, Dan Kramer
  • Publication number: 20140178958
    Abstract: A genetically enhanced cyanobacterial host cell, Cyanobacterium sp. ABICyano1, is disclosed. The enhanced Cyanobacterium sp. ABICyano1 produces a compound or compounds of interest.
    Type: Application
    Filed: December 22, 2013
    Publication date: June 26, 2014
    Applicant: ALGENOL BIOFUELS INC.
    Inventors: Irina Piven, Alexandra Friedrich, Ulf Dühring, Frank Uliczka, Kerstin Baier, Masami Inaba, Tuo Shi, Kui Wang, Heike Enke, Dan Kramer
  • Publication number: 20140011264
    Abstract: The invention provides genetically modified photoautotrophic ethanol producing host cells. Ethanol production is controlled by an inducible promoter. Promoters utilized may be endogenous or heterologous, and genetic modification may be obtained by extrachromosomal means or chromosomal insertion.
    Type: Application
    Filed: July 12, 2013
    Publication date: January 9, 2014
    Applicant: Algenol Biofuels Inc.
    Inventors: Ulf Duhring, Heike Enke, Dan Kramer, Craig Smith, Robert Paul Woods, Kerstin Baier, Christine Oesterhelt
  • Patent number: 8163516
    Abstract: The present invention discloses genetically-modified cyanobacteria with ethanol-production capabilities enhanced over the currently-reported art, and methods of making such cyanobacteria. The invention provides a genetically modified photoautotrophic, ethanol producing host cell comprising an overexpressed pyruvate decarboxylase enzyme converting pyruvate to acetaldehyde and an overexpressed Zn2+ dependent alcohol dehydrogenase enzyme converting acetaldehyde to ethanol.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: April 24, 2012
    Assignee: Algenol Biofuels Inc.
    Inventors: Ulf Dehring, Dan Kramer, Karl Ziegler
  • Publication number: 20110034680
    Abstract: The invention provides for nucleic acid molecules enabling the synthesis of microginin and microginin analogues. The invention also provides for methods for identifying microginins as well creating microginins which may not be found in nature.
    Type: Application
    Filed: October 22, 2010
    Publication date: February 10, 2011
    Applicants: CYANO BIOTECH GMBH, HUMBOLDT-UNIVERSITAET ZU BERLIN
    Inventor: Dan KRAMER
  • Patent number: 7846686
    Abstract: The invention provides for nucleic acid molecules enabling the synthesis of microginin and microginin analogues. The invention also provides for methods for identifying microginins as well creating microginins which may not be found in nature.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: December 7, 2010
    Assignees: Cyano Biotech GmbH, Humboldt-Universitaet zu Berlin
    Inventor: Dan Kramer
  • Publication number: 20100297736
    Abstract: The invention provides genetically modified photoautotrophic ethanol producing host cells. Ethanol production is controlled by an inducible promoter. Promoters utilized may be endogenous or heterologous, and genetic modification may be obtained by extrachromosomal means or chromosomal insertion.
    Type: Application
    Filed: August 6, 2010
    Publication date: November 25, 2010
    Applicant: ALGENOL BIOFUELS, INC.
    Inventors: ULF DUHRING, HEIKE ENKE, DAN KRAMER, CRAIG R. SMITH, R. PAUL WOODS, KERSTIN BAIER, CHRISTINE OESTERHELT
  • Publication number: 20100068776
    Abstract: The invention provides novel compositions of matter for the production of ethanol from carbon dioxide and water. Particularly, the invention provides photoautotrophic organisms having a first and second genetic modification, wherein the first genetic modification improves the ethanol production from organisms having the second genetic modification.
    Type: Application
    Filed: February 9, 2009
    Publication date: March 18, 2010
    Inventors: R. Paul Woods, Craig R. Smith, Dan Kramer, Heike Enke, Kerstin Baier, Ulf Duhring, Karl Ziegler, Wolfgang Lockau, Marianne Grundel, John Coleman, Christine Oesterhelt