Patents by Inventor Dan Lu
Dan Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260176362Abstract: Provided herein are recombinant antibodies, antigen-binding fragments, and fusion proteins thereof useful for binding to and inhibiting programmed death 1 (PD-1), nucleic acid molecules encoding the same and therapeutic compositions thereof, as well as methods of using such antibodies, including the methods for enhancing T cell and NK cell function to increase cell and cytokine mediated immunity and methods of treatment of various immune dysfunction related disorders including cancer and infectious diseases.Type: ApplicationFiled: January 2, 2026Publication date: June 25, 2026Applicant: Kadmon Corporation, LLCInventors: Dan Lu, Zhanna Polonskaya, Tzu-Pei Chang, Stella Aviaty Martomo, Jeegar P. Patel, Faical Miyara
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Patent number: 12636362Abstract: The invention relates to antibodies that bind to VEGFR-2. The antibodies are used for treating neoplastic diseases, hyperproliferative disorders, and angiogenic disorders and can be used alone or in combination with other agents.Type: GrantFiled: March 10, 2023Date of Patent: May 26, 2026Assignee: Kadmon Corporation, LLCInventors: Dan Lu, Zhenping Zhu
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Publication number: 20260119008Abstract: A display control method includes: obtaining a content to be displayed in an external screen of an electronic device in a folded state, wherein a display area of the external screen is divided into a first display area and a second display area; and displaying the content to be displayed through the first display area and the second display area, wherein a display window of the first display area is larger than a display window of the second display area, and a camera is arranged in the second display area.Type: ApplicationFiled: December 27, 2024Publication date: April 30, 2026Inventors: Lu Cheng, Jingjing Wu, Ruxin Zhang, Dan Lu, Han Tang, Jin Gao, Zhe Liang, Leilei Zhang
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Patent number: 12612460Abstract: Provided herein are recombinant antibodies, antigen-binding fragments, and fusion proteins thereof useful for binding to and inhibiting programmed death 1 (PD-1), nucleic acid molecules encoding the same and therapeutic compositions thereof, as well as methods of using such antibodies, including the methods for enhancing T cell and NK cell function to increase cell and cytokine mediated immunity and methods of treatment of various immune dysfunction related disorders including cancer and infectious diseases.Type: GrantFiled: December 20, 2024Date of Patent: April 28, 2026Assignee: Kadmon Corporation, LLCInventors: Dan Lu, Zhanna Polonskaya, Tzu-Pei Chang, Stella Aviaty Martomo, Jeegar P. Patel, Faical Miyara
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Patent number: 12492548Abstract: A reconsolidated bamboo beam-column joint connected by a subassembly and a design method thereof are provided. Rectangular shear steel plates and vertical steel plates in embedded steel plates form an H-shaped section, and left and right ends of the vertical steel plates are embedded in mortises of a reconsolidated bamboo column and a reconsolidated bamboo beam respectively, thereby effectively improving bearing capacity of the joint. A half tenon is provided with an elliptical bolt hole in a penetrating manner and connected to the reconsolidated bamboo column by a bolt, and the half tenon is rotatable along a center of the elliptical bolt hole and movable along a long axis of the elliptical bolt hole, so that the energy is dissipated through friction between the reconsolidated bamboo half tenon and mortises, excellent energy consumption ability of the half tenon structure is exerted, and the anti-pulling resistance of the tenon is improved.Type: GrantFiled: August 16, 2023Date of Patent: December 9, 2025Assignee: Sichuan Provincial Architectural Design And Research Institute Co., Ltd.Inventors: Shixing Zhao, Qiaoling Zhou, Shuheng Yang, Yuanxu Tang, Ziqin Zhong, Jing Xia, Fei He, Qirui Luo, Dan Lu, Feng Xiong, Ming Zhang, Shuwei Chen, Zhixiang Yu, Jinqiu Qi, Yu Yao
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Publication number: 20250147783Abstract: According to one aspect of the present disclosure, a computer-executed method is provided. The method may include receiving a first request sent from a first virtual machine. The first virtual machine may be configured to emulate a host. The method may include establishing communication between the first virtual machine and a second virtual machine in response to the first request. The second virtual machine may be configured to emulate a memory system.Type: ApplicationFiled: November 7, 2023Publication date: May 8, 2025Inventors: Dan Lu, Yi Luo, Yaping Zhang
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Publication number: 20250138765Abstract: A method for displaying an application, includes: determining, in response to receiving by the electronic device a first operation on a target application, a first display window for the target application; determining a first display window parameter of the first display window, and determining, based on the first display window parameter, a target layout framework corresponding to the target application; and displaying the target application in the first display window based on the target layout framework.Type: ApplicationFiled: April 30, 2024Publication date: May 1, 2025Inventors: Xiaodong LI, Jiayan LI, Dan LU, Ruiyao LUO, Siqi LI
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Publication number: 20250136693Abstract: Provided herein are recombinant antibodies, antigen-binding fragments, and fusion proteins thereof useful for binding to and inhibiting programmed death 1 (PD-1), nucleic acid molecules encoding the same and therapeutic compositions thereof, as well as methods of using such antibodies, including the methods for enhancing T cell and NK cell function to increase cell and cytokine mediated immunity and methods of treatment of various immune dysfunction related disorders including cancer and infectious diseases.Type: ApplicationFiled: December 20, 2024Publication date: May 1, 2025Applicant: Kadmon Corporation, LLCInventors: Dan Lu, Zhanna Polonskaya, Tzu-Pei Chang, Stella Aviaty Martomo, Jeegar P. Patel, Faical Miyara
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Publication number: 20250073212Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.Type: ApplicationFiled: May 10, 2024Publication date: March 6, 2025Applicant: Genentech, Inc.Inventors: Andrew POLSON, Shang-Fan YU, Yu-Waye CHU, Michael WENGER, Jamie Harue HIRATA, Dan LU
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Publication number: 20250029303Abstract: The present disclosure provides an animation effect generation method and apparatus, a medium, and a device, and the method includes: in response to determining that an inertial movement of a target element after an end event of a two-dimensional touch movement involves a region outside a first elastic boundary of a display interface, determining collision information for occurrence of a collision rebound according to the first elastic boundary, a motion state of the target element when the end event occurs, and an assumed end-point position; and according to a preset target easing function and the collision information, generating a first animation from the motion state to the occurrence of the collision rebound, and a second animation from the occurrence of the collision rebound to a case where a first boundary of the target element is aligned with the first elastic boundary.Type: ApplicationFiled: May 9, 2023Publication date: January 23, 2025Inventor: Dan LU
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Publication number: 20240320773Abstract: A student occupational ideal-based online and offline hybrid education method and system, an electronic device and a storage medium. The education method includes: acquiring a target career role and first personalized characteristic of a student user; according to the target career role and the first personalized characteristic, matching a first personalized course system and a teacher user corresponding to the student user from within a pre-established career role course module library and a teacher information library; and according to the first personalized course system, providing to the student user online or offline teaching of corresponding course taught by the corresponding teacher user. A personalized education solution is implemented for the career aspirations of each student user by providing the student users with abilities and knowledge curriculum teaching taught by a matching teacher user and corresponding to the career aspirations thereof.Type: ApplicationFiled: April 7, 2022Publication date: September 26, 2024Applicant: Zhejiang Geely Holding Group Co., LtdInventors: Shufu LI, Dan LU
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Patent number: 12016842Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.Type: GrantFiled: April 14, 2021Date of Patent: June 25, 2024Assignee: Genentech, Inc.Inventors: Andrew Polson, Shang-Fan Yu, Yu-Waye Chu, Michael Wenger, Jamie Harue Hirata, Dan Lu
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Publication number: 20240183147Abstract: A reconsolidated bamboo beam-column joint connected by a subassembly and a design method thereof are provided. Rectangular shear steel plates and vertical steel plates in embedded steel plates form an H-shaped section, and left and right ends of the vertical steel plates are embedded in mortises of a reconsolidated bamboo column and a reconsolidated bamboo beam respectively, thereby effectively improving bearing capacity of the joint. A half tenon is provided with an elliptical bolt hole in a penetrating manner and connected to the reconsolidated bamboo column by a bolt, and the half tenon is rotatable along a center of the elliptical bolt hole and movable along a long axis of the elliptical bolt hole, so that the energy is dissipated through friction between the reconsolidated bamboo half tenon and mortises, excellent energy consumption ability of the half tenon structure is exerted, and the anti-pulling resistance of the tenon is improved.Type: ApplicationFiled: August 16, 2023Publication date: June 6, 2024Applicant: Sichuan Provincial Architectural Design And Research Institute Co., Ltd.Inventors: Shixing ZHAO, Qiaoling ZHOU, Shuheng YANG, Yuanxu Tang, Ziqin ZHONG, Jing XIA, Fei HE, Qirui LUO, Dan LU, Feng XIONG, Ming ZHANG, Shuwei CHEN, Zhixiang YU, Jinqiu Qi, Yu YAO
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Publication number: 20240143898Abstract: Provided are a content typesetting method and apparatus, a computer device, and a storage medium. The method includes: acquiring each text element in content to be typeset as well as the element type of each text element (S101); determining rendering size information of each text element on the basis of the element type of each text element and a preset rendering size relationship between element types indicated by a movable character template (S102); and on the basis of the rendering size information of each text element and typesetting style setting information, typesetting the content to be typed (S103). The rendering size of each text element can be determined according to the element type, which avoids a process where the rendering size of each text element needs to be separately measured each time typesetting is performed, thereby improving the computation efficiency of rendering size, and improving typesetting efficiency.Type: ApplicationFiled: June 29, 2022Publication date: May 2, 2024Inventors: Yiyue TAO, Dan LU
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Publication number: 20240144838Abstract: A career aspiration-based educational method and system. The educational method includes: according to the user information, determining and recommending an ideal occupational role for the user to select a target occupational role (S102); searching in a ability and knowledge system library of career roles so as to determine a ability and knowledge system required for the target career role, and pre-establishing a ability and knowledge system library of the career role by means of collecting occupational qualification data (S104); customizing a personalized course system for the user according to the capability and knowledge system required for the target occupational role (S106); and providing the teaching of a corresponding course to the user according to the personalized course system (S108).Type: ApplicationFiled: April 7, 2022Publication date: May 2, 2024Applicant: Zhejiang Geely Holding Group Co., Ltd.Inventors: Shufu LI, Dan LU
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Publication number: 20240059775Abstract: The invention provides antibodies that specifically bind to PD-L1 and fusion molecules comprising PD-L1 binding proteins constructed with an IL 15 receptor-binding domain, nucleic acid molecules encoding the same, and therapeutic compositions thereof. The agents inhibit PD-L1-mediated immunosuppression and enhance cell and cytokine mediated immunity for the treatment of neoplastic and infectious diseases.Type: ApplicationFiled: March 9, 2020Publication date: February 22, 2024Inventors: Samuel D. Waksal, Zhenping Zhu, Yan Wu, Stella A. Martomo, Zhaojing Zhong, Dan Lu
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Publication number: 20240033355Abstract: Provided are methods and compositions for obtaining functionally enhanced derivative effector cells obtained from directed differentiation of genomically engineered iPSCs. The iPSC-derived cells provided herein have stable and functional genome editing that delivers improved or enhanced therapeutic effects. Also provided are therapeutic compositions and the use thereof comprising the functionally enhanced derivative effector cells alone, or with antibodies or checkpoint inhibitors in combination therapies.Type: ApplicationFiled: October 8, 2021Publication date: February 1, 2024Inventors: Dan LU, Bahram VALAMEHR, Eigen PERALTA, Tom LEE, Alec WITTY
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Patent number: 11868783Abstract: Disclosed are a method of underlying drive forwarding and a multi-core system implemented based on a UEFI, which can increase a running speed of the multi-core system implemented based on a UEFI. The underlying drive forwarding method is configured for underlying drive forwarding of a multi-core system. The multi-core system is implemented based on a UEFI and includes an application processor and a bootstrap processor. The bootstrap processor is provided with an execution interface configured to call underlying hardware. The application processor is configured with an instruction interface corresponding to the execution interface.Type: GrantFiled: August 25, 2021Date of Patent: January 9, 2024Assignee: CHANGXIN MEMORY TECHNOLOGIES, INC.Inventors: Yang Wang, Dan Lu, Hao He
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Patent number: 11862278Abstract: The present disclosure relates to a memory test system and a memory test method. The memory test system comprises: a plurality of test devices, a host computer, and driving modules. Each of the test devices is provided with a test interface used for connecting a memory to be tested. The host computer is respectively connected to the plurality of test devices and configured to control the test devices to test the memory to be tested. The driving modules are connected to the test devices and configured to output, to the test devices, driving signals used for driving the test devices to perform data interaction with the host computer.Type: GrantFiled: March 12, 2021Date of Patent: January 2, 2024Assignee: CHANGXIN MEMORY TECHNOLOGIES, INC.Inventors: Hao He, Dan Lu, Yang Wang
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Publication number: 20230416363Abstract: Provided herein are recombinant antibodies, antigen-binding fragments, and fusion proteins thereof useful for binding to and inhibiting programmed death 1 (PD-1), nucleic acid molecules encoding the same and therapeutic compositions thereof, as well as methods of using such antibodies, including the methods for enhancing T cell and NK cell function to increase cell and cytokine mediated immunity and methods of treatment of various immune dysfunction related disorders including cancer and infectious diseases.Type: ApplicationFiled: June 23, 2021Publication date: December 28, 2023Applicant: Kadmon Corporation, LLCInventors: Dan Lu, Zhanna Polonskaya, Tzu-Pei Chang, Stella Aviaty Martomo, Jeegar P. Patel, Faical Miyara