Patents by Inventor Dan Tawfik

Dan Tawfik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Optical sorting method
    Patent number: 6808882
    Abstract: The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; (c) sorting the genetic elements which produce the gene product having the desired activity using a change in the optical properties of the genetic elements. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: October 26, 2004
    Assignee: Medical Research Council
    Inventors: Andrew Griffiths, Dan Tawfik, Armin Sepp
  • In vitro sorting method
    Publication number: 20030124586
    Abstract: The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising of the steps of: (a) compartmentalising genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; (c) sorting the genetic elements which produce the gene product having a desired activity. The invention enables the in vitro evolution of nucleic acids by repeated mutagenesis and iterative applications of the method of the invention.
    Type: Application
    Filed: October 3, 2002
    Publication date: July 3, 2003
    Inventors: Andrew Griffiths, Dan Tawfik
  • In vitro sorting method
    Patent number: 6489103
    Abstract: The invention relates to a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; (b) expressing the genetic elements to produce their respective gene products within the microcapsules; (c) sorting the genetic elements which produce the gene product having a desired activity. The invention permits the in vitro evolution of nucleic acids by repeated mutagenesis and iterative applications of the method of the invention.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: December 3, 2002
    Assignee: Medical Research Council
    Inventors: Andrew Griffiths, Dan Tawfik