Abstract: A laser system may include a laser array comprising a plurality of laser array emitters and a seed laser. The seed laser may be positioned on and directed toward an emitting side of the laser array or may be optically coupled to the plurality of laser array emitters by a waveguide bordering the laser array. The seed laser may be configured to emit a seed beam that interferes with one or more array beams emitted by one or more of the laser array emitters and locks the one or more array beams to a phase of the seed beam. An adjustable micro-lens array positioned on an emitting side of the laser array may enable laser array beams to be steered to a target location.

Abstract: A composition and a use of the composition in the preparation of a medicament for treating eye diseases. The composition includes 0.5-1.5% by weight of a muscarinic acetylcholine receptor M3 agonist; 0.005-0.5% by weight of naphazoline, a pharmaceutically acceptable salt thereof or a combination thereof; and 0.1-1% by weight of ketorolac tromethamine. While enhancing the effect of a muscarinic acetylcholine receptor M3 agonist such as a pilocarpine active ingredient in treating presbyopia, the composition effectively significantly reduces or even eliminates side effects caused by the pilocarpine active ingredient.

Abstract: Provided is a desalination device using a solvent extraction method, comprising: a first mixing tank composed of a feed water inlet into which feed water comprising salt ions and water molecules flows, a first solvent inlet into which a first solvent selectively reacting more with the water molecules than with the salt ions flows, a first mixing tank body in which the feed water and the first solvent are mixed so as to form a mixed water, and a mixed water outlet through which the mixed water is discharged; a first separation tank composed of a mixed water inlet which communicates with the mixed water outlet so that the mixed water flows therein, a first separation tank body in which brine containing salt ions of the feed water and first treatment water formed from mixing the water molecules of the feed water and the first solvent of the mixed water are separated by layer, and a first treatment water outlet through which the first treatment water is discharged; a second mixing tank composed of a first treatme

Abstract: A hybridoma cell line secreting an ActA monoclonal antibody and a use thereof. The hybridoma cell line was deposited on Jul. 8, 2021, at the China Center for Type Culture Collection (CCTCC) with the depository accession number of CCTCC NO: C2021174. The present invention also discloses the ActA monoclonal antibody secreted by this hybridoma cell line or its progeny cell line, a detection kit containing this ActA monoclonal antibody, immunomagnetic beads, the preparation method and use of immunomagnetic beads, and competitive ELISA and indirect ELISA detection methods. The ActA monoclonal antibody of the present invention has the advantages of high titer, good specificity, and strong affinity with the natural antigen. The Listeria competitive ELISA detection kit and immunomagnetic beads developed based on this antibody have high sensitivity and good stability, effectively monitoring the level of ActA antibodies in clinical serum samples, and can be used for labeling Listeria monocytogenes.

Abstract: A method for preparing high-density magnesia-alumina spinel ceramic by low-temperature pressureless sintering, comprises: using MgAl2O4 powder as a raw material powder, adding calcium phosphate as a sintering aid and controlling the calcium element of the calcium phosphate to not exceed 500 ppm of the total mass of the raw material powder; and then performing pressureless sintering, thereby preparing a high-density magnesia-alumina spinel ceramic; the pressureless sintering includes normal pressure sintering or vacuum sintering.

Abstract: Provided is a method for calibrating a deformation pressure of a large-volume press. The method for calibrating the deformation pressure of the large-volume press includes: depositing a conductive layer onto a surface of a bevel plug to obtain a conductive bevel plug; assembling the conductive bevel plug, a molybdenum pillar, a magnesium oxide tube, a magnesium oxide sample chamber, a magnesium oxide octahedron and a calibration standard material, placing a resulting system in the large-volume press, and subjecting the resulting system to a large-volume press pressure correction experiment.

Abstract: Described herein are binding moieties, such as antibodies, that specifically bind Claudin18.2, and chimeric antigen receptors comprising such binding moieties. Further provided are engineered immune cells (such as T cells) comprising anti-Claudin 18.2 chimeric antigen receptors. Also disclosed are methods of treating Claudin18.2-expressing tumor or cancers using the binding moieties, chimeric antigen receptors and engineered immune cells.

Abstract: Aiming at the problem of slow crystallization rate of poly(ethylene furandicarboxylate) (PEF), a preparation method for a bio-based nucleating agent for PEF and an application thereof are disclosed. In a technical solution, glycine having a bio-based source is subjected to an amidation reaction with furoic acid under the catalysis of p-toluenesulfonic acid, followed by an acid-base neutralization reaction with sodium hydroxide to obtain a bio-based nucleating agent for PEF. The bio-based nucleating agent prepared by the present disclosure can significantly accelerate a crystallization rate of PEF. Most importantly, the bio-based nucleating agent has no effect on the bio-based properties of PEF.

Abstract: Display panels are provided according to embodiments of the present disclosure. The display panel includes: a substrate, anodes disposed on the substrate, an inorganic barrier layer, and a pixel definition layer. The inorganic barrier layer includes barrier parts, and the anodes are arranged at intervals between the barrier parts. The pixel definition layer includes pixel definition parts each covering the barrier part and a part of the anode. An orthographic projection of a side of the barrier part adjacent to the substrate on the substrate is located within an orthographic projection of a side of the barrier part away from the substrate on the substrate.

Abstract: The present invention relates to compounds of formula (Ib), wherein R1 to R3, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds.

Abstract: The present disclosure relates to systems and methods for an intelligent assistant (e.g., a chatbot) that can be used to enable a user to generate a machine learning system. Techniques can be used to automatically generate a machine learning system to assist a user. In some cases, the user may not be a software developer and may have little or no experience in either machine learning techniques or software programming. In some embodiments, a user can interact with an intelligent assistant. The interaction can be aural, textual, or through a graphical user interface. The chatbot can translate natural language inputs into a structural representation of a machine learning solution using an ontology. In this way, a user can work with artificial intelligence without being a data scientist to develop, train, refine, and compile machine learning models as stand-alone executable code.

Abstract: Provided in the invention are a catalyst for preparing phosgene and a preparation method therefor, and a method for the preparation of phosgene and the comprehensive utilization of energy thereof. The preparation method comprises the following steps: 1) stirring and soaking activated carbon in a modifying solution, then adding dimethyltin dichloride and chromium oxide powders and carrying out a reaction, and then adding a nickel oxide fine powder and ultrasonically oscillating same to prepare a pre-modified activated carbon; 2) drying the pre-modified activated carbon; and 3) heating and calcinating the dried pre-modified activated carbon from step 2) to prepare the catalyst.

Abstract: A differential-pressure sliding sleeve has an outer cylinder with a flow guiding hole being provided in a wall of the outer cylinder, an inner cylinder arranged in an inner cavity of the outer cylinder, an upper joint extending into the outer cylinder and fixedly connected to an upper end of the outer cylinder, a lower joint extending into the outer cylinder and fixedly connected to a lower end of the outer cylinder, and a dissolvable carrier ring arranged between the lower joint and the inner cylinder. An area of the axial upper end surface of the inner cylinder is greater than that of an axial lower end surface thereof, so that the working fluid generates a pressure difference to provide downward pressure for the inner cylinder, which moves downward under the pressure after the carrier ring is dissolved to open the flow guiding hole.

Abstract: A method of interfacing a discrete digital workshop information system is provided, where the information system includes mutual integration among product lifecycle management (PLM), enterprise resource planning (ERP), a manufacturing execution system (MES), an energy management system (EMS), and a warehouse management system (WMS) of a finished product. A method of interfacing based on a data dictionary fusing different function datasets is proposed to solve the problems of a current discrete industry information system, such as single in function, a small amount of integrated information, a large number of “information islands” existing, incapable of achieving full-process informatization management and control, difficulty in product quality tracing and the like. By the method, it is possible to realize flexible production in a discrete manufacturing industry, precise management and control of a production process, significant improvement in product quality and significant reduction in operating costs.

Abstract: Provided are a 15-PGDH inhibitor and the use thereof. The 15-PGDH inhibitor is a heterocyclic compound as represented by formula I, a solvate thereof, a pharmaceutically acceptable salt thereof, a solvate of a pharmaceutically acceptable salt thereof, or a prodrug thereof. The compound has a good inhibitory effect on 15-PGDH.

Abstract: The present disclosure provides a method, apparatus, medium and device for extracting a river drying-up region and frequency, and belongs to the technical field of remote sensing. The method for extracting a river drying-up region and frequency can be applied to efficiently acquiring river drying-up information for a long time within the large spatial region. With the inverse normalized difference water index (iNDWI) and the maximum value composite (MVC) method for the remote sensing images, the present disclosure omits the troublesome step of separately extracting a river range for each image in the conventional method. In addition, the present disclosure quickly obtains the drying-up frequency by counting the total number of available images and the number of non-water images at the same pixel position, and yields a greater efficiency for extracting the river drying-up region and frequency.

Abstract: Provided is a memory. The memory includes at least one memory array and at least one control circuit, wherein the memory array comprises a plurality of memory cells arranged in an array as well as read wordlines and read bitlines for read operations, wherein each of the memory cells comprises a first transistor and a second transistor. The control circuit is configured to transmit, during a pre-processing stage, a first voltage to the read wordline and the read bitline; transmit, during a pre-charging stage, a second voltage to the read bitline; and transmit, during a read-sensing stage, a third voltage to the read wordline.

Abstract: The present invention provides a mono-p-toluenesulfonate of (S)-(2-((5-chloro-2-((7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)-5-(methoxymethyl)phenyl)dimethyl phosphine oxide, and a hydrate and a crystal form thereof. The crystal form of p-toluenesulfonate has a good stability, is easy to process, and has a high solubility.

Abstract: A composition contains filler particles dispersed in a matrix material, wherein the matrix material contains: (a) 0.01 to 1.50 weight-percent of a first polyorganosiloxane, wherein first polyorganosiloxane is a linear polyorganosiloxane with an average of 2 or more carboxylic acid groups per molecule; and (b) 5 to 30 weight-percent of a second polyorganosiloxane that is free of carboxylic acid groups, wherein the second polyorganosiloxane is a liquid at 25 degrees Celsius and 101 megaPascals pressure; wherein the filler particles are present at a concentration in a range of 15 to less than 78 volume-percent based on composition volume and weight-percent values are relative to weight of the composition and wherein the composition is free of at least one of aliphatic diols and silicone polyethers.

Abstract: Methods, compositions, and kits are provided for the detection of Influenza A in a test sample. The presence or absence of Influenza A in the sample is determined by nucleic acid based assays using primers and/or probes with excellent sensitivity, specificity and inclusivity for detecting Influenza A strains and/or subtypes Detection strategies may utilize loop mediated isothermal amplification (LAMP) and molecular beacon hybridization.