Patents by Inventor Dan Zhao

Dan Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250001368
    Abstract: This disclosure concerns a method of forming a covalent organic framework (COF) membrane, comprising forming a membrane substrate by impregnating a porous polymer with a pore-forming agent in order to form an impregnated polymer, at least partially carbonising the impregnated polymer at a temperature of about 150° C. to about 500° C. in order to form the membrane substrate, and interfacially polymerising amino monomers and acyl monomers on a surface of the membrane substrate in order to form the COF membrane. The membrane substrate is characterised by a crystallinity of about 10% to about 70% relative to the porous polymer. The disclosure also concerns the COF membrane thereof, and the use of the COF membrane in catalyst recovery.
    Type: Application
    Filed: July 27, 2022
    Publication date: January 2, 2025
    Inventors: DAN ZHAO, Hao YANG, Jie WU, Jinhui XU
  • Publication number: 20240417410
    Abstract: The present invention relates to compounds of formula (Ib), wherein R1 to R3, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: August 22, 2024
    Publication date: December 19, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jianguo CHEN, Lei GUO, Haixia LIU, Hong SHEN, Junwei XI, Weixing ZHANG, Dan ZHAO, Wei ZHU
  • Publication number: 20240409654
    Abstract: The present application provides single-domain antibodies targeting BCMA, and chimeric antigen receptors (such as monovalent CAR, and multivalent CAR including bi-epitope CAR) comprising one or more anti-BCMA single-domain antibodies. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating cancer are also provided.
    Type: Application
    Filed: August 28, 2024
    Publication date: December 12, 2024
    Applicant: LEGEND BIOTECH USA INC.
    Inventors: Xiaohu FAN, Qiuchuan ZHUANG, Pingyan WANG, Lin WANG, Lei YANG, Jiaying HAO, Dan ZHAO, Xian HE
  • Publication number: 20240391844
    Abstract: The application provides a preparation method and use of a diatom-bacterium symbiotic organic liquid fertilizer, and belongs to the technical field of biological fertilizers. The preparation method of the diatom-bacterium symbiotic organic liquid fertilizer includes the following steps: (1) mixing a compound bacterial powder with a waste liquid organic matter to allow first fermentation to obtain a small-molecule organic liquid fertilizer; (2) mixing diatom with the small-molecule organic liquid fertilizer to allow second fermentation to obtain a bio-organic fertilizer; and (3) mixing a microbial inoculant with the bio-organic fertilizer to allow third fermentation to obtain the diatom-bacterium symbiotic organic liquid fertilizer. In the application, the diatom-bacterium symbiotic organic liquid fertilizer prepared by the preparation method is used for soil improvement.
    Type: Application
    Filed: May 24, 2024
    Publication date: November 28, 2024
    Inventors: Hui Ding, Xiangci Wu, Chenglong Dai, Dan Zhao
  • Publication number: 20240342663
    Abstract: This disclosure concerns a method of forming a porous material, comprising impregnating a porous polymer with a pore-forming agent in order to form an impregnated polymer, and at least partially carbonising the impregnated polymer at a temperature of about 150° C. to about 500° C. in order to form the porous material. The porous material is characterised by a crystallinity of about 10% to about 70% relative to the porous polymer. This disclosure also concerns the porous material thereof.
    Type: Application
    Filed: July 27, 2022
    Publication date: October 17, 2024
    Inventors: DAN ZHAO, Hao YANG
  • Publication number: 20240278207
    Abstract: Discloses herein is an activated metal-organic framework of formula as defined in the application, and the metal organic framework has a BET surface area of from 250 to 1,000 m2/g as obtained from a 298 K CO2 sorption isotherm. In a particular embodiment, the activated metal-organic framework is aluminium formate (Al(HCOO)3) or vanadium formate (V(HCOO)3).
    Type: Application
    Filed: June 6, 2022
    Publication date: August 22, 2024
    Applicants: c/o National University of Singapore, Agency for Science, Technology and Research
    Inventors: Dinesh Mullangi, Zeyu Deng, Yuxiang Wang, John Wang, Pieremanuele Canepa, Dan Zhao, Anthony Kevin Cheetham, Fengxia Wei
  • Patent number: 12061036
    Abstract: A unit load device, which includes: a box, which is configured to carry cargos and provide heat insulation for the cargos; an optional phase change energy storage material, which is disposed on an inner side face of the box and configured to maintain the temperature of the cargos in the box; and a temperature adjustment module, which is detachably connected to the box to provide cold and/or heat to the box. Different combinations of the box, the temperature adjustment module and the phase change material meet different needs in the cargo transportation process and ensure the transportation efficiency and quality of the cargos.
    Type: Grant
    Filed: October 28, 2020
    Date of Patent: August 13, 2024
    Assignee: CARRIER CORPORATION
    Inventors: Dan Zhao, Zidu Ma
  • Publication number: 20240190802
    Abstract: Disclosed herein are metal organic framework (MOF) suspensions, and sols and compositions comprising MOF nanosheets. Also disclosed herein are their methods of preparation.
    Type: Application
    Filed: April 7, 2022
    Publication date: June 13, 2024
    Applicant: National University of Singapore
    Inventors: Dan Zhao, Hongye Yuan
  • Publication number: 20240109025
    Abstract: Disclosed herein is a composite material comprising: a plurality of water-stable metal-organic frameworks, each having a plurality of porous cavities; and a temperature-sensitive polymeric material in the form of polymer chains, wherein the polymer chains of the temperature-sensitive polymeric material are formed at least partly within the porous cavities of the plurality of water-stable metal-organic frameworks. Also disclosed herein is the use of said composite material for adsorption and release of water.
    Type: Application
    Filed: October 9, 2020
    Publication date: April 4, 2024
    Inventors: Dan Zhao, Avishek Karmakar, Shing Bo Peh
  • Patent number: 11896951
    Abstract: Disclosed herein is a metal organic framework (MOF) having a UTSA-16 structure, where the composition comprises: from 0 to 80 mol % of the total metal in the MOF is a first metal selected from one or more of the group consisting of Cr, Mn, Fe, Ni, Cu, and Co; and from 20 to 100 mol % of the total metal in the MOF is a second metal selected from one or more of the group consisting of Cd, Mn, and Zn.
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: February 13, 2024
    Assignee: National University of Singapore
    Inventors: Dan Zhao, Shing Bo Peh, Avishek Karmakar
  • Publication number: 20230407093
    Abstract: A composition contains: (a) a first polyorganosiloxane; (b) 50-80 volume percent, based on composition volume, of conductive fillers; and (c) 0.1 to 2.0 weight-percent, based on composition weight, of a second polyorganosiloxane different from the first polyorganosiloxane, the second polyorganosiloxane having an average of 0.5 to 1.5 anhydride groups per molecule.
    Type: Application
    Filed: January 13, 2022
    Publication date: December 21, 2023
    Inventors: Dan Zhao, Shane Mangold, Richard Cooper, Dongchan Ahn, Kyle McDonald, Joseph Sootsman, Darren Hansen
  • Publication number: 20230402846
    Abstract: A system generates a first tree structure representing a relation of a plurality of measurement data sets, and generates goodness-of-fit data based on at least a part of attribute data regarding one or more branch portions included in the first tree structure. The attribute data includes one or more attribute values at one or more points in time regarding each of one or more attribute items. The goodness-of-fit data includes goodness-of-fit for each attribute item regarding each branch portion. With regard to each attribute item for each branch portion, goodness-of-fit is a value calculated based on a parent node and two or more child nodes belonging to the relevant branch portion, and one or more attribute values corresponding to the relevant attribute item, and represents a degree that the relevant attribute item will fit as a base of a branch condition.
    Type: Application
    Filed: September 8, 2021
    Publication date: December 14, 2023
    Inventors: Kazuki NAMBA, Masato UTSUMI, Tohru WATANABE, Ikuo SHIGEMORI, Hiroshi IIMURA, Daisuke HAMABA, Dan ZHAO, Hiroaki OGAWA, Jun YAMAZAKI
  • Patent number: 11839869
    Abstract: The present disclosure discloses a method of preparing a Ni active site-loaded C—Si aerogel catalyst, and a product and use thereof, belonging to the technical field of catalyst preparation. The method includes the following steps: (1) dissolving absolute ethanol, trimethoxymethylsilane, cetyltrimethylammonium bromide and HCl in deionized water, conducting hydrolysis to obtain a hydrolyzate, followed by adjusting a pH value of the hydrolyzate to 7 to 8.5, and drying to obtain a C—Si aerogel; and (2) in the absolute ethanol, mixing NiCl2.6H2O with the C—Si aerogel obtained in step (1) uniformly, and conducting ultrasonication, impregnation and drying, followed by calcination to obtain the Ni active site-loaded C—Si aerogel catalyst. In the present disclosure, the prepared Ni active site-loaded C—Si aerogel catalyst is capable of conducting catalytic degradation of aromatic volatile organic compounds (VOCs) at room temperature.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: December 12, 2023
    Assignee: TIANJIN UNIVERSITY
    Inventors: Hui Ding, Dan Zhao, Rui Liu
  • Patent number: 11757723
    Abstract: The present disclosure discloses a distributed secure state reconstruction method based on a double-layer dynamic switching observer.
    Type: Grant
    Filed: March 23, 2022
    Date of Patent: September 12, 2023
    Assignee: SOUTHEAST UNIVERSITY
    Inventors: Guanghui Wen, Xuqiang Lei, Yuezu Lv, Dan Zhao, Jialing Zhou
  • Publication number: 20230208719
    Abstract: The present disclosure discloses a distributed secure state reconstruction method based on a double-layer dynamic switching observer.
    Type: Application
    Filed: March 23, 2022
    Publication date: June 29, 2023
    Inventors: Guanghui WEN, Xuqiang LEI, Yuezu LV, Dan ZHAO, Jialing ZHOU
  • Publication number: 20230191365
    Abstract: Disclosed herein is a metal organic framework (MOF) having a UTSA-16 structure, where the composition comprises: from 0 to 80 mol % of the total metal in the MOF is a first metal selected from one or more of the group consisting of Cr, Mn, Fe, Ni, Cu, and Co; and from 20 to 100 mol % of the total metal in the MOF is a second metal selected from one or more of the group consisting of Cd, Mn, and Zn.
    Type: Application
    Filed: April 19, 2021
    Publication date: June 22, 2023
    Inventors: Dan Zhao, Shing Bo Peh, Avishek Karmakar
  • Patent number: 11655110
    Abstract: The present disclosure relates to a unit load device and a method for storing and transporting articles. The unit load device includes: a housing defining an internal space and an opening to the internal space; and a cover configured to operably open or hermetically close the opening; wherein the housing is provided with a housing temperature control layer containing at least a first phase change material, and/or the cover is provided with a cover temperature control layer containing at least a second phase change material, so that during storage of articles in the internal space hermetically closed by the cover, a temperature of the internal space is within a preset temperature range after a preset period of time has elapsed.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: May 23, 2023
    Assignee: CARRIER CORPORATION
    Inventors: Dan Zhao, Zidu Ma
  • Publication number: 20230086610
    Abstract: A curable composition is disclosed. The curable composition comprises (I) an epoxide-functional silicone-acrylate polymer, (II) an aminosiloxane, and (III) a conductive filler. The epoxide-functional silicone-acrylate polymer comprises acrylate-derived monomeric units comprising siloxane moieties, epoxide-functional moieties, and optionally, hydrocarbyl moieties, and the aminosiloxane comprises an average of at least two amine functional groups per molecule. Methods of preparing the curable composition, and a cured product thereof, are also disclosed. A method of forming a composite article comprising a conductive layer with the curable composition is disclosed is also disclosed. The method comprises disposing the curable composition on a substrate, and curing the curable composition to give a conductive layer on the substrate, thereby forming the composite article.
    Type: Application
    Filed: January 21, 2021
    Publication date: March 23, 2023
    Inventors: Richard COOPER, Jodi M. MECCA, Kangsang LEE, Dongchan AHN, Shane MANGOLD, Dan ZHAO, Kyle MCDONALD, Joseph SOOTSMAN
  • Publication number: 20230076533
    Abstract: The present disclosure discloses a method of preparing a Ni active site-loaded C—Si aerogel catalyst, and a product and use thereof, belonging to the technical field of catalyst preparation. The method includes the following steps: (1) dissolving absolute ethanol, trimethoxymethylsilane, cetyltrimethylammonium bromide and HCl in deionized water, conducting hydrolysis to obtain a hydrolyzate, followed by adjusting a pH value of the hydrolyzate to 7 to 8.5, and drying to obtain a C—Si aerogel; and (2) in the absolute ethanol, mixing NiCl2.6H2O with the C—Si aerogel obtained in step (1) uniformly, and conducting ultrasonication, impregnation and drying, followed by calcination to obtain the Ni active site-loaded C—Si aerogel catalyst. In the present disclosure, the prepared Ni active site-loaded C—Si aerogel catalyst is capable of conducting catalytic degradation of aromatic volatile organic compounds (VOCs) at room temperature.
    Type: Application
    Filed: March 21, 2022
    Publication date: March 9, 2023
    Applicant: TIANJIN UNIVERSITY
    Inventors: Hui DING, Dan ZHAO, Rui LIU
  • Publication number: 20230001379
    Abstract: Disclosed herein is a polycrystalline metal-organic framework membrane comprising a substrate material having a surface and a polycrystalline metal-organic framework attached to the surface of the substrate material, wherein the polycrystalline metal-organic framework is formed from a secondary building unit having the formula Ia or IIb and a ligand as defined in the application.
    Type: Application
    Filed: September 17, 2020
    Publication date: January 5, 2023
    Inventors: Dan Zhao, Linzhi Zhai, Yahui Cai