Patents by Inventor Dandan Liu
Dandan Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240117043Abstract: The present disclosure provides a bispecific antibody including a binding domain that binds to CD112R and a binding domain that binds to TIGIT, and the binding domain that binds to CD112R includes: HCDR1, HCDR2 and HCDR3 of the amino acid sequence set forth in SEQ ID NO: 1, and/or LCDR1, LCDR2 and LCDR3 of the amino acid sequence set forth in SEQ ID NO: 2; and the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 are defined according to the Kabat, IMGT, Chothia, AbM or Contact numbering system. The present disclosure further provides a polynucleotide encoding the antibody, an expression vector, a host cell and a method for expressing and purifying the antibody, a pharmaceutical composition including the antibody of the present disclosure, and use of the bispecific antibody for treating cancer.Type: ApplicationFiled: August 4, 2023Publication date: April 11, 2024Applicants: SHANGHAI JUNSHI BIOSCIENCES CO., LTD., SUZHOU JUNMENG BIOSCIENCES CO., LTD.Inventors: Dandan LIU, Jinwei ZHOU, Yuehua ZHOU, Jing ZHANG, Sheng YAO, Hui FENG, Hui LIU, Hongchuan LIU, Li LI, Qiang ZHAO
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Publication number: 20240109337Abstract: A label printing and attaching system includes a label printing device and a label attaching device. The label printing device has an ink tape supply mechanism for supplying an ink tape with a label pattern. A label tape supply mechanism of the label printing device is adapted to supply a label tape that includes a carrier tape and blank label paper adhered to the carrier tape. The label printing device further includes a heat transfer machine adapted to heat transfer the label pattern on the ink tape onto the blank label paper of the label tape to obtain a desired label. The label attaching device has a label picker adapted to pick up the label with the printed label pattern from the label tape, and a moving device adapted to move the label picker to place the picked label with the printed label pattern onto a product.Type: ApplicationFiled: September 28, 2023Publication date: April 4, 2024Applicants: Tyco Electronics (Dongguan) Ltd., TE Connectivity Solutions GmbH, Tyco Electronics (Shanghai) Co., Ltd.Inventors: Zongjie (Jason) Tao, Hongzhou (Andy) Shen, Dandan (Emily) Zhang, Roberto Francisco-Yi Lu, Guoqiang Liu, Ziqiang Xiong, Kai Fu, Xueyun Zhu, Yi Li, Xuyan Yu
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Publication number: 20240105933Abstract: The present disclosure discloses a high-safety ternary positive electrode material and a method for preparing the same; wherein the ternary positive electrode material has a chemical composition of Lia(NixCoyMn1-x-y)1-bMbO2-cAc, wherein 0.75?a?1.2, 0.75?x<1, 0<y?0.15, 1?x?y>0, 0?b?0.01, 0?c?0.2, M is one or more selected from the group consisting of Al, Zr, Ti, Y, Sr, W and Mg, and A is one or more selected from the group consisting of S, F and N; and CMn?(1?x?y)?0.07; CCo?y?0.05; 0?[CMn?(1?x?y)]/(CCo?y)?2.0. The ternary positive electrode material of the present disclosure is a high-nickel single crystal material with gradient concentration; it has the advantages of high capacity and high thermal stability, and the preparation method is simple, and is suitable for large-scale production.Type: ApplicationFiled: May 18, 2023Publication date: March 28, 2024Inventors: Hui CAO, Yi YAO, Min HOU, Chan LIU, Yingying GUO, Dandan CHEN
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Patent number: 11943170Abstract: A method includes: An access point generates an NDPA frame, where the NDPA frame includes a station information field, and the station information field includes an AID subfield indicating an association identifier AID of a station; the station information field further includes a partial bandwidth information subfield; the partial bandwidth information subfield indicates an RU that is in a bandwidth corresponding to the NDPA frame and for which the station needs to feed back channel state information; and the bandwidth corresponding to the NDPA frame is greater than 160 MHz. The access point transmits the NDPA frame.Type: GrantFiled: August 4, 2023Date of Patent: March 26, 2024Assignee: Huawei Technologies Co., Ltd.Inventors: Jian Yu, Yuchen Guo, Chenchen Liu, Yunbo Li, Ming Gan, Dandan Liang
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Publication number: 20230287462Abstract: The invention is directed to a process to convert carbon dioxide to methane by contacting an aqueous solution comprising dissolved carbon dioxide with an electron charged packed bed comprising of a carrier, suitably activated carbon granules, and a biofilm of microorganisms under anaerobic conditions, wherein more than 90 mol % of the dissolved carbon dioxide in the aqueous solution is present as a bicarbonate ion and/or as a carbonate ion.Type: ApplicationFiled: October 13, 2021Publication date: September 14, 2023Applicant: PAQELL B.V.Inventors: Dandan LIU, Frederikus DE RINK, Johannes Bernardus Maria KLOK
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Patent number: 11655296Abstract: The present invention relates to novel antibodies and antibody fragments thereof that specifically bind to integrin-associated proteins (IAP, or CD47), and a composition comprising the antibodies or the antibody fragments. The present invention also relates to a nucleic acid encoding the antibodies or the antibody fragments thereof, a host cell comprising the nucleic acid, and related use. Furthermore, the present invention also relates to therapeutic and diagnostic use of the antibodies and the antibody fragments.Type: GrantFiled: March 26, 2019Date of Patent: May 23, 2023Assignee: INNOVENT BIOLOGICS (SUZHOU) CO., LTD.Inventors: Dandan Liu, Weifeng Huang, Bingliang Chen, Junjian Liu
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Patent number: 11292836Abstract: The present invention is directed to a novel antibody against CD47 and the antibody fragments thereof and a composition comprising the antibody or antibody fragments thereof. The present invention relates further to a nucleic acid encoding the antibodies or antibody fragments thereof and host cells comprise the same, as well as the relevant use of the same. In addition, the present invention is also directed to the use of these antibodies and antibody fragments in the therapy and diagnosis.Type: GrantFiled: August 28, 2018Date of Patent: April 5, 2022Assignee: INNOVENT BIOLOGICS (SUZHOU) CO., LTD.Inventors: Andy Tsun, Dandan Liu, Bingliang Chen, Junjian Liu
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Publication number: 20210326408Abstract: An ecological flow determination method for considering a lifting amount a belongs to a technical field of environmental engineering and includes the following steps: collecting, by a collecting device, data needed to calculate an ecological flow; determining, by a calculating device, an ecological base flow; selecting an upper limit and a lower limit of the ecological base flow so as to determine a range of the ecological base flow; verifying the lower limit of the ecological base flow; calculating water demands of landscape wetland, sediment discharge and dilution self purification of three service objects; comparing the water demands of the three service objects so as to determine the lifting amount, and finding out a minimum value and a maximum value to determine a lower limit and an upper limit of the lifting amount in the range; combining the ecological base flow and the lifting amount to determine the ecological flow.Type: ApplicationFiled: June 29, 2021Publication date: October 21, 2021Inventors: Jungang Luo, Dandan Liu
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Patent number: 11031455Abstract: The OLED tiled display includes front and back lighting display units that emitting lights toward each other. The front lighting display unit includes a first substrate and a first organic light emitting device. The back lighting display unit includes a second substrate and a second organic light emitting device. The first and second light emitting devices neighbor laterally on each other, but are vertically aligned to a second extended section of the second substrate and a first extended section of the first substrate, respectively. The present invention achieves small gaps and resolves the problem of obvious gaps in an OLED tiled display by piecing together the front and back lighting display units, where the substrate of the front lighting display unit functions as encapsulation layer to the back lighting display unit, and the substrate of the back lighting display unit functions as encapsulation layer to the front lighting display unit.Type: GrantFiled: April 4, 2018Date of Patent: June 8, 2021Assignee: WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Yuejun Tang, Yang Chen, Dandan Liu, Xiaohui Jiang, Tsungying Yang, Dejiun Li
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Publication number: 20210083040Abstract: The OLED tiled display includes front and back lighting display units that emitting lights toward each other. The front lighting display unit includes a first substrate and a first organic light emitting device. The back lighting display unit includes a second substrate and a second organic light emitting device. The first and second light emitting devices neighbor laterally on each other, but are vertically aligned to a second extended section of the second substrate and a first extended section of the first substrate, respectively. The present invention achieves small gaps and resolves the problem of obvious gaps in an OLED tiled display by piecing together the front and back lighting display units, where the substrate of the front lighting display unit functions as encapsulation layer to the back lighting display unit, and the substrate of the back lighting display unit functions as encapsulation layer to the front lighting display unit.Type: ApplicationFiled: April 4, 2018Publication date: March 18, 2021Inventors: Yuejun TANG, Yang CHEN, Dandan LIU, Xiaohui JIANG, Tsungying YANG, Dejiun LI
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Publication number: 20200377593Abstract: The present invention relates to novel antibodies and antibody fragments thereof that specifically bind to integrin-associated proteins (IAP, or CD47), and a composition comprising the antibodies or the antibody fragments. The present invention also relates to a nucleic acid encoding the antibodies or the antibody fragments thereof, a host cell comprising the nucleic acid, and related use. Furthermore, the present invention also relates to therapeutic and diagnostic use of the antibodies and the antibody fragments.Type: ApplicationFiled: March 26, 2019Publication date: December 3, 2020Inventors: Dandan LIU, Weifeng HUANG, Bingliang CHEN, Junjian LIU
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Patent number: 10682421Abstract: There is disclosed a composition in the form of a nanoparticle. The nanoparticle composition has a diameter from 5 to 500 nanometers. The nanoparticle composition has i) a central core portion including magnetic Fe3O4 nanoparticles adapted to act as a heat source when subjected to a magnetic field and a chemotherapeutic agent configured to treat cancer tissues, ii)—a shell portion including a shell member encapsulating said core portion, and iii)—antibodies configured to target cancer stem cells and adhered to surface of said shell member. The chemotherapeutic agent is a heat shock protein inhibitor and is releasable on activation of the heat source due to the magnetic field, and the shell member is made of silica or a silica based material.Type: GrantFiled: March 8, 2018Date of Patent: June 16, 2020Assignee: CITY UNIVERSITY OF HONG KONGInventors: Mengsu Yang, Dandan Liu
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Publication number: 20200181259Abstract: The present invention is directed to a novel antibody against CD47 and the antibody fragments thereof and a composition comprising the antibody or antibody fragments thereof. The present invention relates further to a nucleic acid encoding the antibodies or antibody fragments thereof and host cells comprise the same, as well as the relevant use of the same. In addition, the present invention is also directed to the use of these antibodies and antibody fragments in the therapy and diagnosis.Type: ApplicationFiled: August 28, 2018Publication date: June 11, 2020Inventors: Andy TSUN, Dandan LIU, Bingliang CHEN, Junjian LIU
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Publication number: 20200035196Abstract: A method for adjusting a luminance of a RGBW liquid crystal display is provided by the disclosure. The liquid crystal display includes a RGBW sub-pixel, wherein the luminance of the W sub-pixel is achieved by adjusting one or more of width, spacing, thickness of liquid crystal cell, and number of branch of a sub-pixel electrode corresponding to the W sub-pixel, channel region at the sub-pixel electrode corresponding to the W sub-pixel, and aperture ratio at the sub-pixel electrode corresponding to the W sub-pixel. A liquid crystal display is also provided by the disclosure, and the method for adjusting the luminance of the RGBW liquid crystal display is applicable for the luminance of the W sub-pixel for achieving the adjustment of the luminance of the W sub-pixel.Type: ApplicationFiled: December 14, 2017Publication date: January 30, 2020Inventors: Yuejun TANG, Yang CHEN, Xiaohui JIANG, Dandan LIU
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Patent number: 10416503Abstract: A blue phase liquid crystal display module and device, and a method for manufacturing the same are disclosed. The module includes an upper substrate, a lower substrate disposed oppositely, multiple blue phase liquid crystal molecules disposed between the upper substrate and the lower substrate, multiple upper common electrodes disposed in parallel and spaced at intervals on the upper substrate, multiple lower common electrodes disposed in parallel and spaced at intervals on the lower substrate, wherein the lower common electrodes are staggered with the upper common electrodes, and a pixel electrode disposed on the lower substrate, wherein, the pixel electrode is a hollow concave-convex structure, the pixel electrode has alternating projections and depressions such that multiple oblique electric fields are generated among the pixel electrode, the upper common electrodes and the lower common electrodes in order to drive the blue phase liquid crystal molecules.Type: GrantFiled: April 3, 2018Date of Patent: September 17, 2019Assignee: Wuhan China Star Optoelectronics Technology Co., LtdInventors: Yuejun Tang, Hongqing Cui, De-Jiun Li, Haiyan Sun, Dandan Liu
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Publication number: 20180224703Abstract: A blue phase liquid crystal display module and device, and a method for manufacturing the same are disclosed. The module includes an upper substrate, a lower substrate disposed oppositely, multiple blue phase liquid crystal molecules disposed between the upper substrate and the lower substrate, multiple upper common electrodes disposed in parallel and spaced at intervals on the upper substrate, multiple lower common electrodes disposed in parallel and spaced at intervals on the lower substrate, wherein the lower common electrodes are staggered with the upper common electrodes, and a pixel electrode disposed on the lower substrate, wherein, the pixel electrode is a hollow concave-convex structure, the pixel electrode has alternating projections and depressions such that multiple oblique electric fields are generated among the pixel electrode, the upper common electrodes and the lower common electrodes in order to drive the blue phase liquid crystal molecules.Type: ApplicationFiled: April 3, 2018Publication date: August 9, 2018Applicant: Wuhan China Star Optoelectronics Technology Co., Ltd.Inventors: Yuejun TANG, Hongqing CUI, De-Jiun LI, Haiyan SUN, Dandan LIU
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Publication number: 20180193485Abstract: There is disclosed a composition in the form of a nanoparticle. The nanoparticle composition has a diameter from 5 to 500 nanometers. The nanoparticle composition has i) a central core portion including magnetic Fe3O4 nanoparticles adapted to act as a heat source when subjected to a magnetic field and a chemotherapeutic agent configured to treat cancer tissues, ii)—a shell portion including a shell member encapsulating said core portion, and iii)—antibodies configured to target cancer stem cells and adhered to surface of said shell member. The chemotherapeutic agent is a heat shock protein inhibitor and is releasable on activation of the heat source due to the magnetic field, and the shell member is made of silica or a silica based material.Type: ApplicationFiled: March 8, 2018Publication date: July 12, 2018Applicant: City University of Hong KongInventors: Mengsu YANG, Dandan LIU
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Patent number: 10012860Abstract: A polarizer includes a polarizer base and a plurality of protrusive microstructures being arranged on the polarizer base. The microstructure includes at least two layers of curing-light or thermosetting resin materials. The manufacturing method of the curing-light or thermosetting resin materials includes: providing a polarizer base and coating at least two layers of curing-light or thermosetting resin materials on the polarizer base; and arranging a plurality of lighting dots or heating dots on the curing-light or thermosetting resin materials such that the curing-light or thermosetting resin materials shrink and the lighting dots or heating dots are centers of the shrinkage to form a plurality of protrusive microstructures. In addition, a liquid crystal panel includes the above-mentioned polarizer.Type: GrantFiled: May 21, 2015Date of Patent: July 3, 2018Assignee: Shenzhen China Star Optoelectronics Technology Co., LtdInventors: Dandan Liu, Dejiun Li
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Patent number: 10000047Abstract: The present invention provides a method for manufacturing a curved liquid crystal display panel, which comprises coating a sealing gum on a first or a second frame sealing region; filing liquid crystals between the two substrates and adhering the two substrates together; performing a first curing on partial sealing gum on a first set or a third set of frame bodies; bending the first set and the third set of frame bodies obtained after the first curing along the extension direction of the first set of frame bodies; performing a second curing on uncured sealing gum on the two bended substrates.Type: GrantFiled: May 15, 2015Date of Patent: June 19, 2018Assignee: WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO. LTD.Inventors: Haiyan Sun, Dejiun Li, Tsungying Yang, Dandan Liu
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Patent number: 9964813Abstract: A blue phase liquid crystal display module and device, and a method for manufacturing the same are disclosed. The module includes an upper substrate, a lower substrate disposed oppositely, multiple blue phase liquid crystal molecules disposed between the upper substrate and the lower substrate, multiple upper common electrodes disposed in parallel and spaced at intervals on the upper substrate, multiple lower common electrodes disposed in parallel and spaced at intervals on the lower substrate, wherein the lower common electrodes are staggered with the upper common electrodes, and a pixel electrode disposed on the lower substrate, wherein, the pixel electrode is a hollow concave-convex structure, the pixel electrode has alternating projections and depressions such that multiple oblique electric fields are generated among the pixel electrode, the upper common electrodes and the lower common electrodes in order to drive the blue phase liquid crystal molecules.Type: GrantFiled: August 13, 2015Date of Patent: May 8, 2018Assignee: Wuhan China Star Optoelectronics Technology Co., Ltd.Inventors: Yuejun Tang, Hongqing Cui, De-Jiun Li, Haiyan Sun, Dandan Liu