Abstract: Composite door systems are provided for use in a protective barrier structure. The composite door systems provide for quick assembly, safety, security, and resistance to physical impacts or threats. The composite door systems may include a shell and a core that can be factory completed or finished on site. The shell may be shipped to the assembly location of the barrier structure, and the core may be formed on site by pouring liquid fill material into a cavity of the shell, which is allowed to cure into a solid fill material. Hardware housings may be operatively coupled to the shell that are made to receive door hardware but resist the liquid full material from filling the hardware housings. The shell, core, and/or hardware housings may provide resistance to damage, such as projectiles to provide enhanced security protection to the occupants or contents of the building structure.

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, pharmaceutical compositions comprising the same, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

Abstract: A frame may comprise three or more portions comprising an upper portion disposed adjacent an upper end of an opening and two side portions disposed along either edge of the opening, and in some cases a lower portion adjacent a lower end of an opening. A first frame segment and the second frame segment are adjustable with respect to each other in order to extend around the thickness of the opening. A third segment, such as a soffit segment may be utilized to cover at least a portion of the segments. The first frame segment, the second frame segment, and/or the soffit segment may have one or more barriers located between portions of the segments. The first frame segment may be adjusted with respect to the second frame segment, and the adjustment may be made before or after activation of the one or more barriers.

Abstract: A frame may include three or more portions having an upper portion disposed adjacent an upper end of an opening and two side portions disposed along either edge of the opening, and in some cases a lower portion when the opening is for a window or some doors. A first frame segment and the second frame segment are adjustable with respect to each other in order to extend around the thickness of the door opening. The segments may have one or more thermal barriers, such as a seal (e.g., u-shaped, v-shaped, or the like seal) located between portions of the segments. The first frame segment may be adjusted with respect to the second frame segment. The adjustment of the segments may be made before or after the one or more thermal barriers are installed.

Abstract: A sliding door system having one or more sliding doors, door frames (e.g., static frames of different sizes for different wall thicknesses or adjustable frames that can be used to fit different wall thicknesses), sliding door hardware (e.g., tracks, wheels, soft closers, stops, or the like), header, door receiver, a plurality of seals, or the like. The sliding door system utilizes improvements to the components in order to provide security features, such as electromagnetic (EMC—EMI/RFI) shielding, sound resistance, blast resistance, forced entry and/or ballistic resistance, privacy features, light reduction, fire and/or smoke resistance, or the like to the sliding door system. In particular, the sliding door system allows for the use of the security features with the static or adjustable door frames described herein.

Abstract: A door frame for a sliding door system may include three (3) portions having an upper portion disposed adjacent an upper end of a door opening and two side portions disposed along either edge of the door opening. A first frame segment and the second frame segment are adjustable with respect to each other in order to extend around different thickness of different door openings. The first frame segment and/or the second frame segment may have one or more caps, retainers, headers or the like coupled to the frame segments. The caps, retainers, or headers may have portions that are trimmed in order to allow them to mate with portions of the first frame segment or the second frame segment. The adjustment of the segments may be made before or after being installed.

Abstract: An implanted article physical referencing apparatus comprises a guide body, a first guide shaft and a second guide shaft. The guide body includes a plurality of guide shaft receptacles therein. A longitudinal axis of each of the guide shaft receptacles extends substantially parallel to a longitudinal reference axis of the guide body. The first and second guide shafts each have a proximate end portion and a distal end portion. The proximate end portion of the first guide shaft includes an exterior surface adapted for being engaged with a corresponding interior surface of a selected one of the guide shaft receptacles to constrain unrestricted relative movement between the first guide shaft and the guide body. The proximate end portion of the second guide shaft is attached to the guide body. A longitudinal axis of the second guide shaft extends substantially parallel to the longitudinal reference axis of the guide body.

Abstract: A method of storing a communication path between neighboring home-control networks is provided. Each home-control network includes a network controller and a plurality of network devices. Each network device is configured to transmit and receive messages using at least one of powerline signaling and radio frequency signaling. A server receives a notification from a first network controller indicating that a first network device within a first home-control network received a message transmitted from a second network device within a second home-control network. The server stores an indication of a communication path from the server to the first network device via the second home-control network in a memory of the server.

Abstract: A content distribution facilitation system is described comprising configured servers and a network interface configured to interface with a plurality of terminals in a client server relationship and optionally with a cloud-based storage system. A request from a first source for content comprising content criteria is received, the content criteria comprising content subject matter. At least a portion of the content request content criteria is transmitted to a selected content contributor. If recorded content is received from the first content contributor, the first source is provided with access to the received recorded content. The recorded content may be transmitted via one or more networks to one or more destination devices. Optionally, a voice analysis and/or facial recognition engine are utilized to determine if the recorded content is from the first content contributor.

Abstract: A group definition is received via a network interface. Communications are transmitted to destinations, the communications comprising an invitation to associate with the a content sharing group. Authentication data associated with users that accept the invention is encrypted. The accepting users are associated with the content sharing group. A content gallery definition is received. A communication is received that the content gallery is to be shared with the content sharing group. The content gallery is caused to be instantiated on devices of users associated with the group. A content request for the content sharing group is received and the content request is transmitted accordingly to users associated with the group. A content item is received in response the request and the content item is transmitted to user devices associated with the group and enabled to appear in instantiations of the content gallery on the user devices.

Abstract: Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, pharmaceutical compositions comprising the same, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

Abstract: A group definition is received via a network interface. Communications are transmitted to destinations, the communications comprising an invitation to associate with the a content sharing group. Authentication data associated with users that accept the invention is encrypted. The accepting users are associated with the content sharing group. A content gallery definition is received. A communication is received that the content gallery is to be shared with the content sharing group. The content gallery is caused to be instantiated on devices of users associated with the group. A content request for the content sharing group is received and the content request is transmitted accordingly to users associated with the group. A content item is received in response the request and the content item is transmitted to user devices associated with the group and enabled to appear in instantiations of the content gallery on the user devices.

Abstract: A content distribution facilitation system is described comprising configured servers and a network interface configured to interface with a plurality of terminals in a client server relationship and optionally with a cloud-based storage system. A request from a first source for content comprising content criteria is received, the content criteria comprising content subject matter. At least a portion of the content request content criteria is transmitted to a selected content contributor. If recorded content is received from the first content contributor, the first source is provided with access to the received recorded content. The recorded content may be transmitted via one or more networks to one or more destination devices. Optionally, a voice analysis and/or facial recognition engine are utilized to determine if the recorded content is from the first content contributor.

Abstract: A system includes at least one hardware processor and a memory storing instructions that, when executed by the at least one hardware processor, cause the at least one hardware processor to perform operations including identifying an estate management protocol associated with an estate of a focal subject, the estate management protocol includes an activation event and a plurality of management activities, the activation event defining a triggering event after which the system performs the plurality of management activities to manage the estate of the focal subject, determining that the activation event has occurred, based on the determining, initiating the plurality of estate management activities to manage aspects of the estate of the focal subject using one or more connected devices of the estate, and transmitting management commands to the one or more connected devices to complete the plurality of management activities.

Abstract: A content distribution facilitation system is described comprising configured servers and a network interface configured to interface with a plurality of terminals in a client server relationship and optionally with a cloud-based storage system. A request from a first source for content comprising content criteria is received, the content criteria comprising content subject matter. At least a portion of the content request content criteria is transmitted to a selected content contributor. If recorded content is received from the first content contributor, the first source is provided with access to the received recorded content. The recorded content may be transmitted via one or more networks to one or more destination devices. Optionally, a voice analysis and/or facial recognition engine are utilized to determine if the recorded content is from the first content contributor.

Abstract: Composite door systems are provided for use in a protective barrier structure. The composite door systems provide for quick assembly, safety, security, and resistance to physical impacts or threats. The composite door systems may include a shell and a core that can be factory completed or finished on site. The shell may be shipped to the assembly location of the barrier structure, and the core may be formed on site by pouring liquid fill material into a cavity of the shell, which is allowed to cure into a solid fill material. Hardware housings may be operatively coupled to the shell that are made to receive door hardware but resist the liquid full material from filling the hardware housings. The shell, core, and/or hardware housings may provide resistance to damage, such as projectiles to provide enhanced security protection to the occupants or contents of the building structure.

Abstract: A group definition is received via a network interface. Communications are transmitted to destinations, the communications comprising an invitation to associate with the a content sharing group. Authentication data associated with users that accept the invention is encrypted. The accepting users are associated with the content sharing group. A content gallery definition is received. A communication is received that the content gallery is to be shared with the content sharing group. The content gallery is caused to be instantiated on devices of users associated with the group. A content request for the content sharing group is received and the content request is transmitted accordingly to users associated with the group. A content item is received in response the request and the content item is transmitted to user devices associated with the group and enabled to appear in instantiations of the content gallery on the user devices.

Abstract: Aspects of the disclosure relate to enhanced telematics processing systems with improved third party source data integration features and enhanced customized driving output determinations. A computing platform may receive telematics data and third party source data. The computing platform may enrich the telematics data using the third party source data. After generating the enriched telematics data, the computing platform may use machine learning algorithms and datasets to validate the enriched telematics data. The computing platform may ingest, via a batch ingestion process, the enriched telematics data. For example, the computing platform may store the enriched telematics data and generate additional enriched telematics data until expiration of a predetermined period of time. The computing platform may ingest the enriched telematics data associated with each trip. Once the enriched telematics data has been ingested, the computing platform may generate a standardized common trip format output for each trip.

Abstract: An arc detection method includes classifying whether an arc fault is present in the power system by, for each of a plurality of bins of a current frame of a signal, marking the bin as a candidate bin if a magnitude spectrum of the bin meets first criteria; determining a number of candidate bins in the current frame; marking the number of candidate bins as candidate cluster bins if the number of candidate bins exceeds a minimum cluster size; for each of the candidate cluster bins, determining whether the candidate cluster bin is also a candidate cluster bin of a previous frame of the first signal and if so, identifying the current frame as a candidate frame and incrementing a candidate frame count; and if the candidate frame count exceeds a candidate frame count threshold, determining that an arc fault is present in the power system.