Abstract: A walking vehicle including a chassis and a plurality of wheel-leg components is described. The plurality of wheel-leg components are collectively operable to provide wheeled locomotion and walking locomotion.

Abstract: A walking vehicle including a chassis and a plurality of wheel-leg components is described. The plurality of wheel-leg components are collectively operable to provide wheeled locomotion and walking locomotion.

Abstract: An exercise bicycle having various enhanced or updated features or components is described. For example, the exercise bicycle may include various enhanced brake or braking structures, such as brake locks and brakes having thermal sensing components. The brake, or resistance mechanism, may perform thermal sensing (e.g., measuring a temperature at or around the brake) when the bicycle in being used during an exercise activity, and adjust or modify certain captured parameters (e.g., a resistance applied to a flywheel of the brake and/or a performance output or power level) based on the measured temperature.

Abstract: Systems and methods for operating a hybrid vehicle are provided. The hybrid vehicle may comprise a processor, a chassis, and a plurality of leg-wheel components coupled to the chassis. The plurality of leg-wheel components may be configured to be collectively operable to provide wheeled locomotion and walking locomotion. The processor may be configured to cause the hybrid vehicle to function in one or more of a plurality of modes of operation.

Abstract: A platform-based strength machine enables users to perform strength or lifting activities or exercises via moveable or configurable pull points. The strength machine can include tracks that facilitate the configuring of the positions of the pull points, handles that control operation of the strength machine and/or measure movements performed by a user, compact motors that facilitate various platform or load application configurations, safety systems for the strength machine, and other enhancements.

Abstract: A walking vehicle including a chassis and a plurality of wheel-leg components is described. The plurality of wheel-leg components are collectively operable to provide wheeled locomotion and walking locomotion.

Abstract: In one aspect, a vehicle is provided that includes i) a plurality of wheel-leg components and ii) a surround view imaging system for generating a surround view image of the vehicle. The plurality of wheel-leg components can operate to provide locomotion to the vehicle. The surround view image comprising a 360-degree, three-dimensional view of an environment surrounding the vehicle. The vehicle is configured to operate autonomously using the surround image view to control the locomotion of the plurality of the wheel-leg components.

Abstract: The present disclosure relates generally to methods of treating (i) a tumor (e.g., a solid tumor, an advanced solid tumor, a cancer), (ii) tumor-related weight loss, or (iii) tumor-related cachexia in a human patient, the method comprising administering to the human patient an anti-GDNF family receptor alpha-like (GFRAL) antibody, wherein the antibody inhibits GFRAL binding to Ret proto-oncogene (RET). The present disclosure also relates generally to methods of treating pancreatic cancer (e.g., an advanced pancreatic cancer, a metastatic pancreatic cancer, a pancreatic adenocarcinoma, a metastatic pancreatic adenocarcinoma, an MSI-H pancreatic cancer, a pancreatic ductal adenocarcinoma, a metastatic pancreatic ductal adenocarcinoma) in a human patient, comprising administering to the human patient (i) an anti-GFRAL antibody, wherein the antibody inhibits GFRAL binding to RET; (ii) paclitaxel; and (iii) gemcitabine.

Abstract: An apparatus (1100) for generating an itinerary a travelling object has travelled comprising an input unit configured to receive location information data (3001 . . . 300n) from a mobile computer (1200) of said travelling object; an itinerary generation unit (1113) which is configured to generate itinerary history data (1105) including a plurality of itinerary subsection information data 6001 . . . 600n); and an output unit (1115) which is configured to output at least one itinerary of the travelling object based on the itinerary subsection information data (6001 . . . 600n) and based on a weight value to the mobile computer (1200).

Abstract: Various implementations include an external fixation device for posterior pelvic compression that allows a pin engaged into one iliac bone to be pivoted relative to the pin engaged into the other iliac bone, allowing compression of the iliac bones toward each other and the interposed sacrum and for the relative positions of the pins to be held fixed relative to each other after the compression is set. The pin to be pivoted is engaged into the iliac bone closest to the source of the injury. And, the pins and bars of the fixation device are anteriorly coupled together, which gives the patient greater transportability, as well as maintenance of reduction that will assist in the definitive surgical intervention.

Abstract: In various implementations, a fracture fixation system includes a plate, at least two distal screws, at least one fastener, and at least one wire. The plate has a proximal end, a distal end, and a longitudinal axis that extends between the proximal and distal ends. The plate also includes a distal end portion adjacent the distal end that defines at least two circular openings and an intermediate portion disposed between the proximal end portion and distal end portion. The intermediate portion defines at least one axially oriented elongated slot. The distal screws engage the respective circular openings and a distal end of the bone below a fracture of the bone. The fastener is slidably coupled to the axially oriented elongated slot to prevent movement laterally, rotationally, or angularly of the bone relative to the plate while allowing the proximal and distal portions of the bone to compress the fracture.

Abstract: Various implementations include an external fixation device for posterior pelvic compression that allows a pin engaged into one iliac bone to be pivoted relative to the pin engaged into the other iliac bone, allowing compression of the iliac bones toward each other and the interposed sacrum and for the relative positions of the pins to be held fixed relative to each other after the compression is set. The pin to be pivoted is engaged into the iliac bone closest to the source of the injury. And, the pins and bars of the fixation device are anteriorly coupled together, which gives the patient greater transportability, as well as maintenance of reduction that will assist in the definitive surgical intervention.

Abstract: A system includes one or more processors to request access tokens from a token service computer, cache the access tokens and related information in a token cache, transmit the access tokens with a resource request to a resource server, and receive requested resources in response to the resource request. The resource server transmits representations of requested resources to computing devices having valid tokens. The access tokens and related information including credentials information and token metadata are stored in the token cache.

Abstract: A file system is provided with awareness of “streams” on an SSD to enable more efficient storage of files and other data on the SSD. The file system may be configured to receive a first request from an application to associate a file with a particular stream identifier available on a storage device, intercept one or more subsequent requests to write data to the file, associate the one or more subsequent requests with the stream identifier, and instruct a storage driver associated with the storage device to write the requested data to the identified stream.

Abstract: In this system, regarding an conveyance object placed on a rotary table, based on positions temporarily set previously as a taking position of the disk-shaped conveyance object in a storing container and a reference position of the rotary table, information of the taking position of the conveyance object in the storing container and of the reference position of the rotary table is acquired based on information of the deviation of the conveyance object placed on the rotary table with respect to the reference position of the rotary table acquired by a sensor portion so as to teach a conveying operation of the conveyance object from the storing container to the rotary table by the robot based on the acquired position information.

Abstract: In this system, regarding an conveyance object placed on a rotary table, based on positions temporarily set previously as a taking position of the disk-shaped conveyance object in a storing container and a reference position of the rotary table, information of the taking position of the conveyance object in the storing container and of the reference position of the rotary table is acquired based on information of the deviation of the conveyance object placed on the rotary table with respect to the reference position of the rotary table acquired by a sensor portion so as to teach a conveying operation of the conveyance object from the storing container to the rotary table by the robot based on the acquired position information.

Abstract: A thinly provisioned storage system detects whether physical storage capacity is available when there is a request to allocate storage capacity, prior to data being written to the storage system. In particular, at the time when the file system allocates storage, such as when creating a file or performing an extending write (append) operation, allocating storage to an unallocated region of a sparse file, defragmenting a file, and the like, a storage system can verify that actual physical storage capacity is available. Thus, if there is insufficient actual physical capacity at the time when a storage allocation is attempted, then an error message can be sent and remedial action can be taken.

Abstract: A system includes one or more processors to request access tokens from a token service computer, cache the access tokens and related information in a token cache, transmit the access tokens with a resource request to a resource server, and receive requested resources in response to the resource request. The resource server transmits representations of requested resources to computing devices having valid tokens. The access tokens and related information including credentials information and token metadata are stored in the token cache.

Abstract: Aspects of the present disclosure extend to methods and systems for extending services to existing enterprise systems. In various aspects, one or more service clients may be implemented to provide various functionalities for invoking a specific service that may be protocol dependent. The service client defines a set of standard service properties to specify how to access the specific service. An asset of an enterprise system intending to consume the service may integrate with the service client of the specific service and provide the standard service properties to the service client for service invocation.

Abstract: A system includes one or more processors to request access tokens from a token service computer, cache the access tokens and related information in a token cache, transmit the access tokens with a resource request to a resource server, and receive requested resources in response to the resource request. The resource server transmits representations of requested resources to computing devices having valid tokens. The access tokens and related information including credentials information and token metadata are stored in the token cache.